SI3359146T1 - Farmacevtski sestavki in uporabe, usmerjene na motnje lisosomalnega skladiščenja - Google Patents
Farmacevtski sestavki in uporabe, usmerjene na motnje lisosomalnega skladiščenjaInfo
- Publication number
- SI3359146T1 SI3359146T1 SI201730032T SI201730032T SI3359146T1 SI 3359146 T1 SI3359146 T1 SI 3359146T1 SI 201730032 T SI201730032 T SI 201730032T SI 201730032 T SI201730032 T SI 201730032T SI 3359146 T1 SI3359146 T1 SI 3359146T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pharmaceutical compositions
- lysosomal storage
- storage disorders
- uses directed
- directed
- Prior art date
Links
- 208000015439 Lysosomal storage disease Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1613828.1A GB201613828D0 (en) | 2016-08-11 | 2016-08-11 | Therapeutic agents for lysosomal storage disorders |
GBGB1702552.9A GB201702552D0 (en) | 2017-02-16 | 2017-02-16 | Therapeutic agents for lysosomal storage disorders |
GBGB1705762.1A GB201705762D0 (en) | 2017-04-10 | 2017-04-10 | Therapeutic agents for lysosomal storage disorders |
GBGB1706854.5A GB201706854D0 (en) | 2017-04-28 | 2017-04-28 | Therapeutic agents for lysosomal storage disorders |
EP17767933.9A EP3359146B1 (en) | 2016-08-11 | 2017-08-11 | Pharmaceutical compositions and uses directed to lysosomal storage disorders |
PCT/IB2017/054928 WO2018029657A1 (en) | 2016-08-11 | 2017-08-11 | Pharmaceutical compositions and uses directed to lysosomal storage disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3359146T1 true SI3359146T1 (sl) | 2019-05-31 |
Family
ID=59859423
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201730032T SI3359146T1 (sl) | 2016-08-11 | 2017-08-11 | Farmacevtski sestavki in uporabe, usmerjene na motnje lisosomalnega skladiščenja |
SI201730613T SI3482754T1 (sl) | 2016-08-11 | 2017-08-11 | Farmacevtski sestavki in uporabe usmerjene v motnje lizosomalnega shranjevanja |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201730613T SI3482754T1 (sl) | 2016-08-11 | 2017-08-11 | Farmacevtski sestavki in uporabe usmerjene v motnje lizosomalnega shranjevanja |
Country Status (28)
Country | Link |
---|---|
US (3) | US11400067B2 (sl) |
EP (4) | EP3865126A1 (sl) |
JP (3) | JP7393943B2 (sl) |
KR (3) | KR102412724B1 (sl) |
CN (1) | CN109843275A (sl) |
AU (2) | AU2017308864B2 (sl) |
BR (1) | BR112019002719A2 (sl) |
CA (1) | CA3033557A1 (sl) |
CY (2) | CY1121345T1 (sl) |
DK (2) | DK3482754T3 (sl) |
ES (2) | ES2849566T3 (sl) |
HK (1) | HK1253282B (sl) |
HR (2) | HRP20190344T1 (sl) |
HU (2) | HUE041914T2 (sl) |
IL (1) | IL264610A (sl) |
LT (2) | LT3482754T (sl) |
MA (2) | MA43876B1 (sl) |
MD (2) | MD3482754T2 (sl) |
ME (1) | ME03340B (sl) |
MX (2) | MX2019001577A (sl) |
PL (2) | PL3359146T3 (sl) |
PT (2) | PT3359146T (sl) |
RS (2) | RS61442B1 (sl) |
RU (2) | RU2021115932A (sl) |
SG (1) | SG11201901048VA (sl) |
SI (2) | SI3359146T1 (sl) |
TN (1) | TN2019000032A1 (sl) |
WO (1) | WO2018029657A1 (sl) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD3482754T2 (ro) * | 2016-08-11 | 2021-05-31 | Intrabio Ltd | Compoziții farmaceutice și utilizări direcționate spre tulburări de stocare lizozomale |
GB201709459D0 (en) | 2017-06-14 | 2017-07-26 | Intrabio Ltd | Treatment for migraine |
MX2021006559A (es) * | 2018-12-06 | 2021-08-16 | Intrabio Ltd | Analogos deuterados de acetil-leucina. |
CN114040757A (zh) | 2019-03-02 | 2022-02-11 | 内在生物技术有限公司 | 用于治疗疾病的亮氨酸、乙酰基亮氨酸和相关类似物 |
EP3989962A1 (en) | 2019-06-28 | 2022-05-04 | IntraBio Ltd | Combination therapy with acetyl-leucine and miglustat |
WO2022264037A1 (en) * | 2021-06-14 | 2022-12-22 | Intrabio Ltd. | Branched-chain amino acid derivatives to treat disease |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2749512B1 (fr) * | 1996-06-10 | 1999-08-13 | Pf Medicament | Utilisation de l'acetyl dl leucine pour le traitement des tremblements |
WO2001097829A2 (en) | 2000-06-19 | 2001-12-27 | Genzyme Corporation | Combination enzyme replacement, gene therapy and small molecule therapy for lysosomal storage diseases |
FR2883180B1 (fr) | 2005-03-18 | 2007-05-25 | Pierre Fabre Medicament Sa | Utilisation de l'acetyl-leucine pour la preparation d'un medicament destine au traitement de troubles de l'equilibre |
FR2905600B1 (fr) | 2006-09-13 | 2010-01-15 | Pf Medicament | Traitement des vertiges par l'acetyl-l-leucine. |
WO2009114729A2 (en) * | 2008-03-14 | 2009-09-17 | Irm Llc | Compounds, compositions and methods for treating lysosomal storage diseases and disorders |
TN2010000251A1 (fr) * | 2010-06-03 | 2011-11-11 | Rekik Raouf | N-acetyl-dl-leucine medicament neuro et retino protecteur |
GB201114017D0 (en) | 2011-08-15 | 2011-09-28 | Univ Dundee | Inhibitors against endosomal/ysosomal enzymes |
CA2915127A1 (en) | 2012-06-06 | 2013-12-12 | Giancarlo PARENTI | Allosteric chaperones and uses thereof |
ES2733677T3 (es) * | 2016-08-11 | 2019-12-02 | Intrabio Ltd | Agentes terapéuticos para enfermedades neurodegenerativas |
MD3482754T2 (ro) * | 2016-08-11 | 2021-05-31 | Intrabio Ltd | Compoziții farmaceutice și utilizări direcționate spre tulburări de stocare lizozomale |
-
2017
- 2017-08-11 MD MDE20190593T patent/MD3482754T2/ro unknown
- 2017-08-11 PL PL17767933T patent/PL3359146T3/pl unknown
- 2017-08-11 AU AU2017308864A patent/AU2017308864B2/en active Active
- 2017-08-11 RU RU2021115932A patent/RU2021115932A/ru unknown
- 2017-08-11 PT PT17767933T patent/PT3359146T/pt unknown
- 2017-08-11 ES ES18210763T patent/ES2849566T3/es active Active
- 2017-08-11 WO PCT/IB2017/054928 patent/WO2018029657A1/en active Application Filing
- 2017-08-11 ME MEP-2019-60A patent/ME03340B/me unknown
- 2017-08-11 EP EP20215877.0A patent/EP3865126A1/en active Pending
- 2017-08-11 RS RS20210064A patent/RS61442B1/sr unknown
- 2017-08-11 MA MA43876A patent/MA43876B1/fr unknown
- 2017-08-11 SI SI201730032T patent/SI3359146T1/sl unknown
- 2017-08-11 US US16/324,301 patent/US11400067B2/en active Active
- 2017-08-11 CA CA3033557A patent/CA3033557A1/en active Pending
- 2017-08-11 MA MA055947A patent/MA55947A/fr unknown
- 2017-08-11 KR KR1020197007024A patent/KR102412724B1/ko active IP Right Grant
- 2017-08-11 MX MX2019001577A patent/MX2019001577A/es unknown
- 2017-08-11 DK DK18210763.1T patent/DK3482754T3/da active
- 2017-08-11 SI SI201730613T patent/SI3482754T1/sl unknown
- 2017-08-11 CN CN201780062740.XA patent/CN109843275A/zh active Pending
- 2017-08-11 RS RS20190334A patent/RS58478B1/sr unknown
- 2017-08-11 KR KR1020227039341A patent/KR20220154849A/ko not_active IP Right Cessation
- 2017-08-11 HU HUE17767933A patent/HUE041914T2/hu unknown
- 2017-08-11 PT PT182107631T patent/PT3482754T/pt unknown
- 2017-08-11 HU HUE18210763A patent/HUE052837T2/hu unknown
- 2017-08-11 EP EP18210763.1A patent/EP3482754B1/en active Active
- 2017-08-11 EP EP24154769.4A patent/EP4342461A3/en active Pending
- 2017-08-11 PL PL18210763T patent/PL3482754T3/pl unknown
- 2017-08-11 TN TNP/2019/000032A patent/TN2019000032A1/en unknown
- 2017-08-11 ES ES17767933T patent/ES2716133T3/es active Active
- 2017-08-11 MD MDE20181131T patent/MD3359146T2/ro unknown
- 2017-08-11 JP JP2019507811A patent/JP7393943B2/ja active Active
- 2017-08-11 KR KR1020227009897A patent/KR102467953B1/ko active IP Right Grant
- 2017-08-11 BR BR112019002719-0A patent/BR112019002719A2/pt active Search and Examination
- 2017-08-11 RU RU2019106493A patent/RU2749515C2/ru active
- 2017-08-11 LT LTEP18210763.1T patent/LT3482754T/lt unknown
- 2017-08-11 LT LTEP17767933.9T patent/LT3359146T/lt unknown
- 2017-08-11 DK DK17767933.9T patent/DK3359146T3/en active
- 2017-08-11 SG SG11201901048VA patent/SG11201901048VA/en unknown
- 2017-08-11 EP EP17767933.9A patent/EP3359146B1/en active Active
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2018
- 2018-10-02 HK HK18112571.2A patent/HK1253282B/zh unknown
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2019
- 2019-02-03 IL IL264610A patent/IL264610A/en unknown
- 2019-02-07 MX MX2021008432A patent/MX2021008432A/es unknown
- 2019-02-21 HR HRP20190344TT patent/HRP20190344T1/hr unknown
- 2019-03-08 CY CY20191100279T patent/CY1121345T1/el unknown
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2021
- 2021-01-12 CY CY20211100017T patent/CY1123844T1/el unknown
- 2021-01-29 HR HRP20210153TT patent/HRP20210153T1/hr unknown
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2022
- 2022-01-07 JP JP2022001694A patent/JP2022050564A/ja active Pending
- 2022-06-30 US US17/854,027 patent/US20220331278A1/en active Pending
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2023
- 2023-05-10 AU AU2023202903A patent/AU2023202903A1/en active Pending
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2024
- 2024-02-02 US US18/430,858 patent/US20240197663A1/en active Pending
- 2024-02-27 JP JP2024027864A patent/JP2024059863A/ja active Pending
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