PL3359146T3 - Kompozycje farmaceutyczne i zastosowania ukierunkowane na lizosomalne zaburzenia spichrzeniowe - Google Patents
Kompozycje farmaceutyczne i zastosowania ukierunkowane na lizosomalne zaburzenia spichrzenioweInfo
- Publication number
- PL3359146T3 PL3359146T3 PL17767933T PL17767933T PL3359146T3 PL 3359146 T3 PL3359146 T3 PL 3359146T3 PL 17767933 T PL17767933 T PL 17767933T PL 17767933 T PL17767933 T PL 17767933T PL 3359146 T3 PL3359146 T3 PL 3359146T3
- Authority
- PL
- Poland
- Prior art keywords
- pharmaceutical compositions
- lysosomal storage
- storage disorders
- uses directed
- directed
- Prior art date
Links
- 208000015439 Lysosomal storage disease Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1613828.1A GB201613828D0 (en) | 2016-08-11 | 2016-08-11 | Therapeutic agents for lysosomal storage disorders |
| GBGB1702552.9A GB201702552D0 (en) | 2017-02-16 | 2017-02-16 | Therapeutic agents for lysosomal storage disorders |
| GBGB1705762.1A GB201705762D0 (en) | 2017-04-10 | 2017-04-10 | Therapeutic agents for lysosomal storage disorders |
| GBGB1706854.5A GB201706854D0 (en) | 2017-04-28 | 2017-04-28 | Therapeutic agents for lysosomal storage disorders |
| PCT/IB2017/054928 WO2018029657A1 (en) | 2016-08-11 | 2017-08-11 | Pharmaceutical compositions and uses directed to lysosomal storage disorders |
| EP17767933.9A EP3359146B1 (en) | 2016-08-11 | 2017-08-11 | Pharmaceutical compositions and uses directed to lysosomal storage disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3359146T3 true PL3359146T3 (pl) | 2019-07-31 |
Family
ID=59859423
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18210763T PL3482754T3 (pl) | 2016-08-11 | 2017-08-11 | Kompozycje farmaceutyczne i zastosowania ukierunkowane na lizosomalne zaburzenia spichrzeniowe |
| PL17767933T PL3359146T3 (pl) | 2016-08-11 | 2017-08-11 | Kompozycje farmaceutyczne i zastosowania ukierunkowane na lizosomalne zaburzenia spichrzeniowe |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18210763T PL3482754T3 (pl) | 2016-08-11 | 2017-08-11 | Kompozycje farmaceutyczne i zastosowania ukierunkowane na lizosomalne zaburzenia spichrzeniowe |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US11400067B2 (pl) |
| EP (4) | EP3359146B1 (pl) |
| JP (3) | JP7393943B2 (pl) |
| KR (3) | KR20220154849A (pl) |
| CN (1) | CN109843275A (pl) |
| AU (2) | AU2017308864B2 (pl) |
| BR (1) | BR112019002719A2 (pl) |
| CA (1) | CA3033557A1 (pl) |
| CY (2) | CY1121345T1 (pl) |
| DK (2) | DK3482754T3 (pl) |
| ES (2) | ES2849566T3 (pl) |
| HK (1) | HK1253282B (pl) |
| HR (2) | HRP20190344T1 (pl) |
| HU (2) | HUE041914T2 (pl) |
| IL (1) | IL264610A (pl) |
| LT (2) | LT3482754T (pl) |
| MA (2) | MA55947A (pl) |
| MD (2) | MD3482754T2 (pl) |
| ME (1) | ME03340B (pl) |
| MX (2) | MX2019001577A (pl) |
| PL (2) | PL3482754T3 (pl) |
| PT (2) | PT3482754T (pl) |
| RS (2) | RS61442B1 (pl) |
| RU (2) | RU2021115932A (pl) |
| SG (1) | SG11201901048VA (pl) |
| SI (2) | SI3482754T1 (pl) |
| TN (1) | TN2019000032A1 (pl) |
| WO (1) | WO2018029657A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019001577A (es) * | 2016-08-11 | 2019-08-29 | Intrabio Ltd | Composiciones farmaceuticas y usos dirigidos a los trastornos del almacenamiento lisosomal. |
| GB201709459D0 (en) | 2017-06-14 | 2017-07-26 | Intrabio Ltd | Treatment for migraine |
| KR20210111757A (ko) * | 2018-12-06 | 2021-09-13 | 인트라바이오 리미티드 | 아세틸-류신의 중수소화된 유사체 |
| WO2020178721A1 (en) | 2019-03-02 | 2020-09-10 | Intrabio Ltd. | Leucine, acetyl leucine, and related analogs for treating disease |
| US20220362189A1 (en) | 2019-06-28 | 2022-11-17 | Intrabio Ltd. | Combination therapy with acetyl-leucine and miglustat |
| WO2022264037A1 (en) * | 2021-06-14 | 2022-12-22 | Intrabio Ltd. | Branched-chain amino acid derivatives to treat disease |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2749512B1 (fr) * | 1996-06-10 | 1999-08-13 | Pf Medicament | Utilisation de l'acetyl dl leucine pour le traitement des tremblements |
| US20020095135A1 (en) * | 2000-06-19 | 2002-07-18 | David Meeker | Combination enzyme replacement, gene therapy and small molecule therapy for lysosomal storage diseases |
| FR2883180B1 (fr) * | 2005-03-18 | 2007-05-25 | Pierre Fabre Medicament Sa | Utilisation de l'acetyl-leucine pour la preparation d'un medicament destine au traitement de troubles de l'equilibre |
| FR2905600B1 (fr) * | 2006-09-13 | 2010-01-15 | Pf Medicament | Traitement des vertiges par l'acetyl-l-leucine. |
| WO2009114729A2 (en) * | 2008-03-14 | 2009-09-17 | Irm Llc | Compounds, compositions and methods for treating lysosomal storage diseases and disorders |
| TN2010000251A1 (fr) * | 2010-06-03 | 2011-11-11 | Rekik Raouf | N-acetyl-dl-leucine medicament neuro et retino protecteur |
| GB201114017D0 (en) | 2011-08-15 | 2011-09-28 | Univ Dundee | Inhibitors against endosomal/ysosomal enzymes |
| CA2915127A1 (en) * | 2012-06-06 | 2013-12-12 | Giancarlo PARENTI | Allosteric chaperones and uses thereof |
| MX2019001577A (es) * | 2016-08-11 | 2019-08-29 | Intrabio Ltd | Composiciones farmaceuticas y usos dirigidos a los trastornos del almacenamiento lisosomal. |
| PL3416631T3 (pl) * | 2016-08-11 | 2019-11-29 | Intrabio Ltd | Środki terapeutyczne do leczenia chorób neurodegeneracyjnych |
-
2017
- 2017-08-11 MX MX2019001577A patent/MX2019001577A/es unknown
- 2017-08-11 MA MA055947A patent/MA55947A/fr unknown
- 2017-08-11 ES ES18210763T patent/ES2849566T3/es active Active
- 2017-08-11 KR KR1020227039341A patent/KR20220154849A/ko not_active IP Right Cessation
- 2017-08-11 RS RS20210064A patent/RS61442B1/sr unknown
- 2017-08-11 CA CA3033557A patent/CA3033557A1/en active Pending
- 2017-08-11 SI SI201730613T patent/SI3482754T1/sl unknown
- 2017-08-11 MD MDE20190593T patent/MD3482754T2/ro unknown
- 2017-08-11 JP JP2019507811A patent/JP7393943B2/ja active Active
- 2017-08-11 PT PT182107631T patent/PT3482754T/pt unknown
- 2017-08-11 HU HUE17767933A patent/HUE041914T2/hu unknown
- 2017-08-11 PL PL18210763T patent/PL3482754T3/pl unknown
- 2017-08-11 EP EP17767933.9A patent/EP3359146B1/en active Active
- 2017-08-11 LT LTEP18210763.1T patent/LT3482754T/lt unknown
- 2017-08-11 TN TNP/2019/000032A patent/TN2019000032A1/en unknown
- 2017-08-11 EP EP20215877.0A patent/EP3865126A1/en active Pending
- 2017-08-11 AU AU2017308864A patent/AU2017308864B2/en active Active
- 2017-08-11 RU RU2021115932A patent/RU2021115932A/ru unknown
- 2017-08-11 KR KR1020197007024A patent/KR102412724B1/ko active IP Right Grant
- 2017-08-11 SG SG11201901048VA patent/SG11201901048VA/en unknown
- 2017-08-11 US US16/324,301 patent/US11400067B2/en active Active
- 2017-08-11 BR BR112019002719-0A patent/BR112019002719A2/pt active Search and Examination
- 2017-08-11 EP EP24154769.4A patent/EP4342461A3/en active Pending
- 2017-08-11 RS RS20190334A patent/RS58478B1/sr unknown
- 2017-08-11 HU HUE18210763A patent/HUE052837T2/hu unknown
- 2017-08-11 PT PT17767933T patent/PT3359146T/pt unknown
- 2017-08-11 DK DK18210763.1T patent/DK3482754T3/da active
- 2017-08-11 WO PCT/IB2017/054928 patent/WO2018029657A1/en active Application Filing
- 2017-08-11 MD MDE20181131T patent/MD3359146T2/ro unknown
- 2017-08-11 PL PL17767933T patent/PL3359146T3/pl unknown
- 2017-08-11 SI SI201730032T patent/SI3359146T1/sl unknown
- 2017-08-11 ES ES17767933T patent/ES2716133T3/es active Active
- 2017-08-11 EP EP18210763.1A patent/EP3482754B1/en active Active
- 2017-08-11 LT LTEP17767933.9T patent/LT3359146T/lt unknown
- 2017-08-11 MA MA43876A patent/MA43876B1/fr unknown
- 2017-08-11 ME MEP-2019-60A patent/ME03340B/me unknown
- 2017-08-11 CN CN201780062740.XA patent/CN109843275A/zh active Pending
- 2017-08-11 KR KR1020227009897A patent/KR102467953B1/ko active IP Right Grant
- 2017-08-11 DK DK17767933.9T patent/DK3359146T3/en active
- 2017-08-11 RU RU2019106493A patent/RU2749515C2/ru active
-
2018
- 2018-10-02 HK HK18112571.2A patent/HK1253282B/zh unknown
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2019
- 2019-02-03 IL IL264610A patent/IL264610A/en unknown
- 2019-02-07 MX MX2021008432A patent/MX2021008432A/es unknown
- 2019-02-21 HR HRP20190344TT patent/HRP20190344T1/hr unknown
- 2019-03-08 CY CY20191100279T patent/CY1121345T1/el unknown
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2021
- 2021-01-12 CY CY20211100017T patent/CY1123844T1/el unknown
- 2021-01-29 HR HRP20210153TT patent/HRP20210153T1/hr unknown
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2022
- 2022-01-07 JP JP2022001694A patent/JP2022050564A/ja active Pending
- 2022-06-30 US US17/854,027 patent/US20220331278A1/en active Pending
-
2023
- 2023-05-10 AU AU2023202903A patent/AU2023202903A1/en active Pending
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2024
- 2024-02-27 JP JP2024027864A patent/JP2024059863A/ja active Pending
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