SI3215133T1 - Postopki in sestavki v zvezi z uporabo površinsko aktivnih snovi z nizkim HLB v proizvodnji sintetičnih nanonosilcev, ki vsebujejo rapalog - Google Patents

Postopki in sestavki v zvezi z uporabo površinsko aktivnih snovi z nizkim HLB v proizvodnji sintetičnih nanonosilcev, ki vsebujejo rapalog

Info

Publication number
SI3215133T1
SI3215133T1 SI201531494T SI201531494T SI3215133T1 SI 3215133 T1 SI3215133 T1 SI 3215133T1 SI 201531494 T SI201531494 T SI 201531494T SI 201531494 T SI201531494 T SI 201531494T SI 3215133 T1 SI3215133 T1 SI 3215133T1
Authority
SI
Slovenia
Prior art keywords
rapalog
production
methods
synthetic nanocarriers
low hlb
Prior art date
Application number
SI201531494T
Other languages
English (en)
Inventor
Conlin O'neil
Aaron P. Griset
David H. Altreuter
Original Assignee
Selecta Biosciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Selecta Biosciences, Inc. filed Critical Selecta Biosciences, Inc.
Publication of SI3215133T1 publication Critical patent/SI3215133T1/sl

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0003Invertebrate antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
SI201531494T 2014-11-05 2015-11-05 Postopki in sestavki v zvezi z uporabo površinsko aktivnih snovi z nizkim HLB v proizvodnji sintetičnih nanonosilcev, ki vsebujejo rapalog SI3215133T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462075864P 2014-11-05 2014-11-05
US201462075866P 2014-11-05 2014-11-05
PCT/US2015/059349 WO2016073798A1 (en) 2014-11-05 2015-11-05 Methods and compositions related to the use of low hlb surfactants in the production of synthetic nanocarriers comprising a rapalog
EP15798601.9A EP3215133B1 (en) 2014-11-05 2015-11-05 Methods and compositions related to the use of low hlb surfactants in the production of synthetic nanocarriers comprising a rapalog

Publications (1)

Publication Number Publication Date
SI3215133T1 true SI3215133T1 (sl) 2021-07-30

Family

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Family Applications (1)

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SI201531494T SI3215133T1 (sl) 2014-11-05 2015-11-05 Postopki in sestavki v zvezi z uporabo površinsko aktivnih snovi z nizkim HLB v proizvodnji sintetičnih nanonosilcev, ki vsebujejo rapalog

Country Status (23)

Country Link
US (2) US20160128986A1 (sl)
EP (6) EP3215133B1 (sl)
JP (5) JP7218089B2 (sl)
KR (2) KR102601922B1 (sl)
CN (5) CN113244191A (sl)
AU (4) AU2015342969B2 (sl)
BR (3) BR112017008720A2 (sl)
CA (2) CA2966850C (sl)
CY (1) CY1124418T1 (sl)
DK (4) DK3215192T3 (sl)
EA (2) EA201790978A1 (sl)
ES (2) ES2846809T3 (sl)
FI (2) FI3834823T3 (sl)
HR (1) HRP20210098T1 (sl)
HU (2) HUE053094T2 (sl)
IL (7) IL296246A (sl)
LT (1) LT3215133T (sl)
MX (4) MX2017005904A (sl)
PL (1) PL3215133T3 (sl)
PT (1) PT3215133T (sl)
RS (1) RS61359B1 (sl)
SI (1) SI3215133T1 (sl)
WO (2) WO2016073798A1 (sl)

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ES2846809T3 (es) 2021-07-29
WO2016073798A1 (en) 2016-05-12
IL280518A (en) 2021-03-01
IL251622A0 (en) 2017-06-29
EP3215192A4 (en) 2018-05-02
IL251622B (en) 2021-06-30
EP3215133B1 (en) 2020-10-28
DK3215133T3 (da) 2021-02-01
AU2021209202B2 (en) 2023-11-30
EP3215133A1 (en) 2017-09-13
MX2017005904A (es) 2017-06-27
JP6912377B2 (ja) 2021-08-04
AU2021209204A1 (en) 2021-08-19
BR122021025344B1 (pt) 2024-02-20
EA201790978A1 (ru) 2017-09-29
IL296246A (en) 2022-11-01
MX2017005903A (es) 2017-06-27
CY1124418T1 (el) 2022-07-22
FI3906918T3 (fi) 2024-04-04
KR102656139B1 (ko) 2024-04-11
CN115212186A (zh) 2022-10-21
CA2966852C (en) 2024-01-02
EP4360633A2 (en) 2024-05-01
CN107072965A (zh) 2017-08-18
IL280518B (en) 2022-01-01
US20160128986A1 (en) 2016-05-12
PL3215133T3 (pl) 2021-06-14
EP3906918A1 (en) 2021-11-10
CA2966852A1 (en) 2016-05-12
EP3215192A1 (en) 2017-09-13
EP3906918B1 (en) 2024-01-03
KR102601922B1 (ko) 2023-11-15
RS61359B1 (sr) 2021-02-26
IL295292A (en) 2022-10-01
BR112017008720A2 (pt) 2017-12-19
DK3906918T3 (da) 2024-04-08
JP7218089B2 (ja) 2023-02-06
BR112017008499A2 (pt) 2017-12-26
EP3834823B1 (en) 2024-01-03
EA201790977A1 (ru) 2017-10-31
CN115212187A (zh) 2022-10-21
CN107072965B (zh) 2021-05-11
US20160128987A1 (en) 2016-05-12
JP2021143180A (ja) 2021-09-24
IL251620A0 (en) 2017-06-29
CA2966850C (en) 2024-03-26
MX2021012273A (es) 2021-11-12
IL288609A (en) 2022-02-01
AU2021209202A1 (en) 2021-08-19
MX2021006698A (es) 2021-07-07
JP2017537081A (ja) 2017-12-14
DK3215192T3 (da) 2021-05-03
KR20170081660A (ko) 2017-07-12
BR112017008499B1 (pt) 2023-10-03
EP3215192B1 (en) 2021-02-17
AU2015342969A1 (en) 2017-04-27
WO2016073799A1 (en) 2016-05-12
PT3215133T (pt) 2021-01-29
IL283699B (en) 2022-09-01
JP2022173236A (ja) 2022-11-18
DK3834823T3 (da) 2024-04-08
ES2865375T3 (es) 2021-10-15
CA2966850A1 (en) 2016-05-12
HRP20210098T1 (hr) 2021-03-05
IL288609B (en) 2022-10-01
FI3834823T3 (fi) 2024-04-02
KR20170081659A (ko) 2017-07-12
HUE054894T2 (hu) 2021-10-28
CN113244191A (zh) 2021-08-13
LT3215133T (lt) 2021-02-25
AU2015342968A1 (en) 2017-04-27
AU2015342968B2 (en) 2021-05-27
JP2017533243A (ja) 2017-11-09
IL288609B2 (en) 2023-02-01
CN107072964A (zh) 2017-08-18
EP3834823A1 (en) 2021-06-16
IL283699A (en) 2021-07-29
WO2016073799A9 (en) 2016-12-08
JP2023169893A (ja) 2023-11-30
IL251620B (en) 2021-02-28
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AU2015342969B2 (en) 2021-05-27
HUE053094T2 (hu) 2021-06-28

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