SI3129492T1 - Kemijsko encimski proces za pripravo laktonov in makrocikličnih ketonov - Google Patents

Kemijsko encimski proces za pripravo laktonov in makrocikličnih ketonov

Info

Publication number
SI3129492T1
SI3129492T1 SI201531310T SI201531310T SI3129492T1 SI 3129492 T1 SI3129492 T1 SI 3129492T1 SI 201531310 T SI201531310 T SI 201531310T SI 201531310 T SI201531310 T SI 201531310T SI 3129492 T1 SI3129492 T1 SI 3129492T1
Authority
SI
Slovenia
Prior art keywords
chemo
lactones
preparation
enzymatic process
macrocyclic ketones
Prior art date
Application number
SI201531310T
Other languages
English (en)
Inventor
Cardayre Stephen B. Del
Andreas W. Schirmer
Myong Ko
Haibo Wang
Original Assignee
Genomatica, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica, Inc. filed Critical Genomatica, Inc.
Publication of SI3129492T1 publication Critical patent/SI3129492T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
SI201531310T 2014-04-10 2015-04-10 Kemijsko encimski proces za pripravo laktonov in makrocikličnih ketonov SI3129492T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461978176P 2014-04-10 2014-04-10
PCT/US2015/025452 WO2015157719A1 (en) 2014-04-10 2015-04-10 Semisynthetic routes to organic compounds
EP15718726.1A EP3129492B1 (en) 2014-04-10 2015-04-10 Chemo-enzymatic process for the preparation of lactones and macrocyclic ketones

Publications (1)

Publication Number Publication Date
SI3129492T1 true SI3129492T1 (sl) 2020-11-30

Family

ID=53005703

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201531310T SI3129492T1 (sl) 2014-04-10 2015-04-10 Kemijsko encimski proces za pripravo laktonov in makrocikličnih ketonov

Country Status (13)

Country Link
US (2) US11008597B2 (sl)
EP (2) EP3739057A1 (sl)
JP (3) JP6680690B2 (sl)
KR (1) KR102493892B1 (sl)
CN (1) CN106164282A (sl)
AU (3) AU2015243186C1 (sl)
BR (1) BR112016023232B1 (sl)
CA (1) CA2944558A1 (sl)
ES (1) ES2811083T3 (sl)
MX (2) MX2016013240A (sl)
MY (1) MY198279A (sl)
SI (1) SI3129492T1 (sl)
WO (1) WO2015157719A1 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2016013240A (es) * 2014-04-10 2017-05-03 Reg Life Sciences Llc Rutas semi-sinteticas para compuestos organicos.
US10676763B2 (en) 2014-07-18 2020-06-09 Genomatica, Inc. Microbial production of fatty diols
WO2019050990A1 (en) * 2017-09-05 2019-03-14 The Regents Of The University Of California HOST CELLS AND METHODS FOR PRODUCING ALKYL LACTONE BY CYCLING HYDROXYL FATTY ACID
WO2019086583A1 (en) * 2017-11-01 2019-05-09 Evolva Sa Production of macrocyclic ketones in recombinant hosts
EP3844269A4 (en) * 2018-08-31 2022-07-27 Genomatica, Inc. PRODUCTION OF NON-NATIVE MONO-UNSATURATED FATTY ACIDS IN BACTERIA
WO2020150362A1 (en) * 2019-01-18 2020-07-23 Genomatica, Inc. Enzymatic biosynthesis of lactones
US11952609B2 (en) 2021-03-01 2024-04-09 Battelle Energy Alliance, Llc Methods of producing succinic acid from a biomass

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2234551A (en) 1941-03-11 Preparation of lactones
US3681395A (en) * 1970-03-11 1972-08-01 Int Flavors & Fragrances Inc Preparation of ambrettolide
US3963571A (en) 1974-04-10 1976-06-15 Phillips Petroleum Company Oxidation of hydroxy acids produced from bacterial oxidation of paraffins
US4014902A (en) 1976-06-09 1977-03-29 International Flavors & Fragrances Inc. Intermediate in the process for the preparation of trans-Δ9 -isoambrettolide
US4709058A (en) 1986-09-19 1987-11-24 National Distillers And Chemical Corporation Process for the production of macrocyclic esters by the depolymerization of polyesters
US5424202A (en) 1988-08-31 1995-06-13 The University Of Florida Ethanol production by recombinant hosts
US5000000A (en) 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
US5482846A (en) 1988-08-31 1996-01-09 University Of Florida Ethanol production in Gram-positive microbes
US5028539A (en) 1988-08-31 1991-07-02 The University Of Florida Ethanol production using engineered mutant E. coli
JPH03219886A (ja) * 1989-07-20 1991-09-27 Quest Internatl Bv デルタ―ラクトンの製造方法
US5215901A (en) * 1989-07-20 1993-06-01 Unilever Patent Holdings B.V. Process for producing delta-lactones from 11-hydroxy fatty acids
US5602030A (en) 1994-03-28 1997-02-11 University Of Florida Research Foundation Recombinant glucose uptake system
DE19515888A1 (de) 1995-04-29 1996-10-31 Huels Chemische Werke Ag Verfahren zur kontinuierlichen Herstellung von macrocyclischen Verbindungen
FR2775285B1 (fr) * 1998-02-20 2000-04-14 Synarome H Fraysse Et Cie Procede de fabrication de la cis-isoambrettolide et son application
DE10232750A1 (de) 2002-07-18 2004-02-05 Basf Ag Verfahren zur Herstellung von macrocyclischen Ketonen durch Dieckmann-Kondensation in der Gasphase
ITMI20040717A1 (it) * 2004-04-09 2004-07-09 Adorkem Technology Spa Procedimento chemo-enzimatico per la preparazione dell'escitalopram
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
US8110093B2 (en) 2007-03-14 2012-02-07 Ls9, Inc. Process for producing low molecular weight hydrocarbons from renewable resources
WO2008119735A1 (en) * 2007-04-02 2008-10-09 Georg-August-Universität Göttingen Method of producing hydroxy fatty acids
CA2692266C (en) 2007-09-27 2019-04-16 Ls9, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
WO2009085278A1 (en) 2007-12-21 2009-07-09 Ls9, Inc. Methods and compositions for producing olefins
WO2009140695A1 (en) 2008-05-16 2009-11-19 Ls9, Inc. Methods and compositions for producing hydrocarbons
US8232924B2 (en) 2008-05-23 2012-07-31 Alliant Techsystems Inc. Broadband patch antenna and antenna system
JP2012504963A (ja) 2008-10-07 2012-03-01 エルエス９・インコーポレイテッド 脂肪アルデヒドを生産するための方法および組成物
US9175234B2 (en) 2008-12-23 2015-11-03 REG Life Sciences, LLC Methods and compositions related to thioesterase enzymes
CN102482676A (zh) 2009-05-01 2012-05-30 加州大学评议会 来源于生物质聚合物的脂肪酸脂产物
US20110162259A1 (en) 2009-09-25 2011-07-07 Ls9, Inc. Production of fatty acid derivatives
US8530221B2 (en) 2010-01-14 2013-09-10 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
US8372610B2 (en) 2010-09-15 2013-02-12 Ls9, Inc. Production of odd chain fatty acid derivatives in recombinant microbial cells
WO2012071439A1 (en) * 2010-11-22 2012-05-31 The Regents Of The University Of California Host cells and methods for producing diacid compounds
WO2013019647A1 (en) * 2011-08-03 2013-02-07 Ls9, Inc. Production of fatty acids and derivatives thereof having improved aliphatic chain length and saturation characteristics
US20130177951A1 (en) * 2012-01-06 2013-07-11 Eastman Chemical Company Chemo-enzymatic process for preparing quaternary ammonium esters
EP2984490B1 (en) * 2013-06-14 2020-05-20 Genomatica, Inc. Methods of producing omega-hydroxylated fatty acid derivatives
MX2016013240A (es) * 2014-04-10 2017-05-03 Reg Life Sciences Llc Rutas semi-sinteticas para compuestos organicos.

Also Published As

Publication number Publication date
EP3129492B1 (en) 2020-06-03
CA2944558A1 (en) 2015-10-15
WO2015157719A9 (en) 2016-08-04
WO2015157719A1 (en) 2015-10-15
EP3739057A1 (en) 2020-11-18
KR20160146795A (ko) 2016-12-21
EP3129492A1 (en) 2017-02-15
JP7266646B2 (ja) 2023-04-28
BR112016023232B1 (pt) 2023-03-14
US11008597B2 (en) 2021-05-18
JP2020110174A (ja) 2020-07-27
MY198279A (en) 2023-08-21
ES2811083T3 (es) 2021-03-10
JP2017512485A (ja) 2017-05-25
JP6680690B2 (ja) 2020-04-15
AU2015243186A8 (en) 2017-02-02
AU2021204482A1 (en) 2021-07-29
CN106164282A (zh) 2016-11-23
MX2016013240A (es) 2017-05-03
MX2020013096A (es) 2021-02-17
WO2015157719A8 (en) 2015-12-17
AU2015243186C1 (en) 2020-04-02
US20210310033A1 (en) 2021-10-07
US20170029854A1 (en) 2017-02-02
BR112016023232A2 (pt) 2018-05-15
JP6931107B2 (ja) 2021-09-01
AU2015243186A1 (en) 2016-11-24
AU2015243186B2 (en) 2019-10-03
AU2019232831A1 (en) 2019-10-10
AU2021204482B2 (en) 2023-03-16
KR102493892B1 (ko) 2023-01-31
JP2021180678A (ja) 2021-11-25
AU2019232831B2 (en) 2021-04-29

Similar Documents

Publication Publication Date Title
IL250744A0 (en) A method for preparing flavociclib and its pharmaceutical preparations
EP3262071B8 (en) Method of using anti-cd79b immunoconjugates
EP3137125A4 (en) Structural porous biomaterial and implant formed of same
SI3380530T1 (sl) Izboljšan postopek za pripravo sugamadeksa in njegovih intermediatov
IL247155A0 (en) Rapamycin for the treatment of lymphangioleiomyomatosis
EP3239221A4 (en) Porous silicone object and process for producing same
EP3218005A4 (en) Glycan-interacting compounds and methods of use
SI3129492T1 (sl) Kemijsko encimski proces za pripravo laktonov in makrocikličnih ketonov
EP2951158A4 (en) PROCESS FOR THE PREPARATION OF IVACAFTOR AND SOLVATES THEREOF
EP3107904A4 (en) Substituted delta-lactones and methods of preparing same
EP3180297A4 (en) Process for the manufacture of furural and furfural derivatives
EP3099493A4 (en) Printbars and methods of forming printbars
EP3227298A4 (en) Process for the preparation of baricitinib and an intermediate thereof
EP3137907A4 (en) Methods and compositions for the diagnosis and treatment of kawasaki disease
GB201604110D0 (en) Preparation of macrocyclic lactones
EP3236963A4 (en) Method of treatment
EP3119199A4 (en) Compounds and their methods of use
EP3160412A4 (en) Absorbent articles and methods of making
GB201709604D0 (en) Tea solid composition and process of making the same
HUP1400543A2 (hu) Eljárás és köztitermék apixaban elõállítására
HUP1500647A2 (en) Intermediate of baricitinib and process for its preparation
SG11201608250YA (en) Polymer powder composition and its method of preparation
EP3142999A4 (en) Methods and compositions of dasotraline for treatment of adhd
IL237572A0 (en) Process and intermediates for the preparation of dastinib
HK1232209A1 (zh) 製備 -乙酰氧基丙酸及其衍生物的方法