SI2866797T1 - Stabilni injekcijski farmacevtski sestavek antagonista neurokinin 1 receptorja in postopek za njegovo pripravo - Google Patents
Stabilni injekcijski farmacevtski sestavek antagonista neurokinin 1 receptorja in postopek za njegovo pripravoInfo
- Publication number
- SI2866797T1 SI2866797T1 SI201231807T SI201231807T SI2866797T1 SI 2866797 T1 SI2866797 T1 SI 2866797T1 SI 201231807 T SI201231807 T SI 201231807T SI 201231807 T SI201231807 T SI 201231807T SI 2866797 T1 SI2866797 T1 SI 2866797T1
- Authority
- SI
- Slovenia
- Prior art keywords
- neurokinin
- preparation
- pharmaceutical composition
- receptor antagonist
- injectable pharmaceutical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12756353.4A EP2866797B1 (en) | 2012-07-06 | 2012-07-06 | Stable injectable pharmaceutical composition of neurokinin 1 receptor antagonist and process for preparation thereof |
| PCT/EP2012/002854 WO2014005606A1 (en) | 2012-07-06 | 2012-07-06 | Stable injectable pharmaceutical composition of neurokinin 1 receptor antagonist and process for preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2866797T1 true SI2866797T1 (sl) | 2020-08-31 |
Family
ID=46826407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201231807T SI2866797T1 (sl) | 2012-07-06 | 2012-07-06 | Stabilni injekcijski farmacevtski sestavek antagonista neurokinin 1 receptorja in postopek za njegovo pripravo |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20150165045A1 (sl) |
| EP (1) | EP2866797B1 (sl) |
| CY (1) | CY1123370T1 (sl) |
| DK (1) | DK2866797T3 (sl) |
| ES (1) | ES2798103T3 (sl) |
| HR (1) | HRP20201138T1 (sl) |
| HU (1) | HUE051147T2 (sl) |
| LT (1) | LT2866797T (sl) |
| PL (1) | PL2866797T3 (sl) |
| PT (1) | PT2866797T (sl) |
| RS (1) | RS60599B1 (sl) |
| SI (1) | SI2866797T1 (sl) |
| WO (1) | WO2014005606A1 (sl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2750246T3 (es) | 2013-10-08 | 2020-03-25 | Innopharma Inc | Formulaciones liquidas orales de aprepitant |
| US20160324881A1 (en) * | 2013-12-30 | 2016-11-10 | Oncoprevent Gmbh | Neurokinin-1 Receptor Antagonists For Use In A Method Of Prevention Of Cancer |
| EP3171894B1 (en) * | 2014-07-24 | 2021-03-24 | Plus Vitech, S.L. | Neurokinin-1 receptor antagonist composition for treatment of diseases and conditions of the respiratory tract |
| US9808465B2 (en) | 2014-09-19 | 2017-11-07 | Heron Therapeutics, Inc. | Emulsion formulations of aprepitant |
| WO2017021880A1 (en) * | 2015-08-03 | 2017-02-09 | Leiutis Pharmaceuticals Pvt Ltd | Liquid formulations of fosaprepitant |
| US9913853B2 (en) | 2015-11-03 | 2018-03-13 | Cipla Limited | Stabilized liquid fosaprepitant formulations |
| US9974742B2 (en) | 2016-02-01 | 2018-05-22 | Heron Therapeutics, Inc. | Emulsion formulations of an NK-1 receptor antagonist and uses thereof |
| KR20180118136A (ko) * | 2016-02-01 | 2018-10-30 | 헤론 테라퓨틱스 인코포레이티드 | Nk-1 수용체 길항제를 포함하는 에멀젼 |
| MD3435980T2 (ro) * | 2016-06-06 | 2020-03-31 | Helsinn Healthcare Sa | Formulări injectabile de fosnetupitant echilibrate fiziologic |
| CN109789154B (zh) * | 2016-08-03 | 2021-05-14 | 珠海贝海生物技术有限公司 | 福沙吡坦和阿瑞吡坦的制剂 |
| US20190231688A1 (en) * | 2018-01-30 | 2019-08-01 | Heron Therapeutics, Inc. | Method of administering emulsion formulations of an nk-1 receptor antagonist |
| US11654154B2 (en) | 2019-01-29 | 2023-05-23 | Navinta Iii Inc | Process for preparing injectable Fosaprepitant Dimeglumine compositions having improved storage stability |
| CN112168788B (zh) * | 2019-07-01 | 2022-07-19 | 中国医学科学院药物研究所 | 静脉注射用阿瑞匹坦胶束无菌冻干制剂及其制备方法 |
| CN110559255B (zh) * | 2019-09-06 | 2022-08-19 | 南京医科大学 | Zl006温敏凝胶及其制备方法 |
| JP2024518225A (ja) * | 2022-04-14 | 2024-05-01 | ウィズダム・ファーマスーティカル・カンパニー・リミテッド | 医薬組成物及びアプレピタント注射液並びに凍結乾燥粉末注射剤 |
| CN115944745B (zh) * | 2022-12-01 | 2024-03-22 | 石河子大学 | 一种具有聚集诱导发光性质的活性氧响应型药物控释体系及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0916346A3 (en) | 1991-09-20 | 2000-12-06 | Glaxo Group Limited | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis |
| TW385308B (en) | 1994-03-04 | 2000-03-21 | Merck & Co Inc | Prodrugs of morpholine tachykinin receptor antagonists |
| AU2005299748B2 (en) * | 2004-10-21 | 2009-04-09 | Tgel Bio Co., Ltd | In situ controlled release drug delivery system |
| US9227958B2 (en) * | 2006-02-03 | 2016-01-05 | Glenmark Pharmaceuticals Limited | Amorphous and crystalline forms of aprepitant and processes for the preparation thereof |
| US20090285862A1 (en) * | 2006-05-03 | 2009-11-19 | Cnsbio Pty Ltd. | Methods and composition for treatment of inflammatory pain |
| US20070265329A1 (en) | 2006-05-12 | 2007-11-15 | Devang Shah T | Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) |
| US20100151035A1 (en) * | 2007-03-13 | 2010-06-17 | Sandoz Ag | Pharmaceutical compositions of poorly soluble drugs |
| EP3090743A1 (en) * | 2008-01-09 | 2016-11-09 | Charleston Laboratories, Inc. | Pharmaceutical compositions for treating headache and eliminating nausea |
| NZ588715A (en) * | 2008-05-29 | 2012-11-30 | Albany Molecular Res Inc | 5-ht3 receptor modulators, methods of making, and use thereof |
| CA2767576C (en) * | 2009-07-08 | 2020-03-10 | Charleston Laboratories Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
| HUP1000325A2 (en) * | 2010-06-18 | 2012-01-30 | Druggability Technologies Ip Holdco Jersey Ltd | Nanostructured aprepitant compositions and process for their preparation |
-
2012
- 2012-07-06 HU HUE12756353A patent/HUE051147T2/hu unknown
- 2012-07-06 WO PCT/EP2012/002854 patent/WO2014005606A1/en active Application Filing
- 2012-07-06 SI SI201231807T patent/SI2866797T1/sl unknown
- 2012-07-06 LT LTEP12756353.4T patent/LT2866797T/lt unknown
- 2012-07-06 PT PT127563534T patent/PT2866797T/pt unknown
- 2012-07-06 ES ES12756353T patent/ES2798103T3/es active Active
- 2012-07-06 EP EP12756353.4A patent/EP2866797B1/en active Active
- 2012-07-06 PL PL12756353T patent/PL2866797T3/pl unknown
- 2012-07-06 DK DK12756353.4T patent/DK2866797T3/da active
- 2012-07-06 US US14/412,147 patent/US20150165045A1/en not_active Abandoned
- 2012-07-06 RS RS20200846A patent/RS60599B1/sr unknown
-
2020
- 2020-04-17 US US16/851,779 patent/US20200237920A1/en not_active Abandoned
- 2020-07-07 CY CY20201100624T patent/CY1123370T1/el unknown
- 2020-07-20 HR HRP20201138TT patent/HRP20201138T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LT2866797T (lt) | 2020-06-25 |
| US20150165045A1 (en) | 2015-06-18 |
| WO2014005606A1 (en) | 2014-01-09 |
| HRP20201138T1 (hr) | 2020-10-30 |
| CY1123370T1 (el) | 2021-12-31 |
| HUE051147T2 (hu) | 2021-03-01 |
| EP2866797A1 (en) | 2015-05-06 |
| PL2866797T3 (pl) | 2020-11-02 |
| ES2798103T3 (es) | 2020-12-09 |
| RS60599B1 (sr) | 2020-08-31 |
| EP2866797B1 (en) | 2020-04-29 |
| US20200237920A1 (en) | 2020-07-30 |
| DK2866797T3 (da) | 2020-08-03 |
| PT2866797T (pt) | 2020-07-22 |
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