PL2866797T3 - Stabilna, nadająca się do wstrzykiwania kompozycja farmaceutyczna antagonisty receptora neurokininy-1 i sposób jej wytwarzania - Google Patents
Stabilna, nadająca się do wstrzykiwania kompozycja farmaceutyczna antagonisty receptora neurokininy-1 i sposób jej wytwarzaniaInfo
- Publication number
- PL2866797T3 PL2866797T3 PL12756353T PL12756353T PL2866797T3 PL 2866797 T3 PL2866797 T3 PL 2866797T3 PL 12756353 T PL12756353 T PL 12756353T PL 12756353 T PL12756353 T PL 12756353T PL 2866797 T3 PL2866797 T3 PL 2866797T3
- Authority
- PL
- Poland
- Prior art keywords
- neurokinin
- preparation
- pharmaceutical composition
- receptor antagonist
- injectable pharmaceutical
- Prior art date
Links
- 229940123821 Neurokinin 1 receptor antagonist Drugs 0.000 title 1
- PFPSZGPAQFBVHZ-UHFFFAOYSA-N n-(3-chlorophenyl)-2-[(4-phenyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical group ClC1=CC=CC(NC(=O)CSC=2N(C(C=3C=CN=CC=3)=NN=2)C=2C=CC=CC=2)=C1 PFPSZGPAQFBVHZ-UHFFFAOYSA-N 0.000 title 1
- 239000002742 neurokinin 1 receptor antagonist Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fencing (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2012/002854 WO2014005606A1 (en) | 2012-07-06 | 2012-07-06 | Stable injectable pharmaceutical composition of neurokinin 1 receptor antagonist and process for preparation thereof |
| EP12756353.4A EP2866797B1 (en) | 2012-07-06 | 2012-07-06 | Stable injectable pharmaceutical composition of neurokinin 1 receptor antagonist and process for preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2866797T3 true PL2866797T3 (pl) | 2020-11-02 |
Family
ID=46826407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12756353T PL2866797T3 (pl) | 2012-07-06 | 2012-07-06 | Stabilna, nadająca się do wstrzykiwania kompozycja farmaceutyczna antagonisty receptora neurokininy-1 i sposób jej wytwarzania |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20150165045A1 (pl) |
| EP (1) | EP2866797B1 (pl) |
| CY (1) | CY1123370T1 (pl) |
| DK (1) | DK2866797T3 (pl) |
| ES (1) | ES2798103T3 (pl) |
| HR (1) | HRP20201138T1 (pl) |
| HU (1) | HUE051147T2 (pl) |
| LT (1) | LT2866797T (pl) |
| PL (1) | PL2866797T3 (pl) |
| PT (1) | PT2866797T (pl) |
| RS (1) | RS60599B1 (pl) |
| SI (1) | SI2866797T1 (pl) |
| SM (1) | SMT202000385T1 (pl) |
| WO (1) | WO2014005606A1 (pl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2926424C (en) | 2013-10-08 | 2018-01-09 | Innopharma, Inc. | Aprepitant oral liquid formulations |
| JP2017502973A (ja) * | 2013-12-30 | 2017-01-26 | オンコプレフェント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌を予防する方法において使用するためのニューロキニン−１受容体アンタゴニスト |
| CA2956022A1 (en) * | 2014-07-24 | 2016-01-28 | Plus Vitech,S.L | Neurokinin-1 receptor antagonist composition for treatment of diseases and conditions of the respiratory tract |
| CN106852118A (zh) | 2014-09-19 | 2017-06-13 | 赫伦治疗有限公司 | 阿瑞吡坦乳剂制剂 |
| WO2017021880A1 (en) * | 2015-08-03 | 2017-02-09 | Leiutis Pharmaceuticals Pvt Ltd | Liquid formulations of fosaprepitant |
| US9913853B2 (en) | 2015-11-03 | 2018-03-13 | Cipla Limited | Stabilized liquid fosaprepitant formulations |
| AU2016391046A1 (en) * | 2016-02-01 | 2018-08-16 | Heron Therapeutics, Inc. | Emulsion comprising an NK-1 receptor antagonist |
| US9974742B2 (en) | 2016-02-01 | 2018-05-22 | Heron Therapeutics, Inc. | Emulsion formulations of an NK-1 receptor antagonist and uses thereof |
| PT3435980T (pt) | 2016-06-06 | 2020-02-21 | Helsinn Healthcare Sa | Formulações injetáveis fisiologicamente equilibradas de fosnetupitant |
| CN113288862B (zh) * | 2016-08-03 | 2023-06-02 | 珠海贝海生物技术有限公司 | 含阿瑞吡坦的组合物及其制备方法和应用 |
| JP2021512091A (ja) * | 2018-01-30 | 2021-05-13 | ヘロン セラピューティクス， インコーポレイテッドＨｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ｎｋ−１受容体アンタゴニストのエマルジョン製剤の投与方法 |
| US11654154B2 (en) | 2019-01-29 | 2023-05-23 | Navinta Iii Inc | Process for preparing injectable Fosaprepitant Dimeglumine compositions having improved storage stability |
| CN112168788B (zh) * | 2019-07-01 | 2022-07-19 | 中国医学科学院药物研究所 | 静脉注射用阿瑞匹坦胶束无菌冻干制剂及其制备方法 |
| CN110559255B (zh) * | 2019-09-06 | 2022-08-19 | 南京医科大学 | Zl006温敏凝胶及其制备方法 |
| EP4288060A4 (en) * | 2022-04-14 | 2024-08-07 | Wisdom Pharmaceutical Co., Ltd. | PHARMACEUTICAL COMPOSITION AND INJECTION OF APREPITANT AND INJECTION OF LYOPHILIZED POWDER |
| CN115944745B (zh) * | 2022-12-01 | 2024-03-22 | 石河子大学 | 一种具有聚集诱导发光性质的活性氧响应型药物控释体系及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1082959A1 (en) | 1991-09-20 | 2001-03-14 | Glaxo Group Limited | NK1 Antagonists for the treatment of depression |
| IL112778A0 (en) | 1994-03-04 | 1995-05-26 | Merck & Co Inc | Substituted heterocycles, their preparation and pharmaceutical compositions containing them |
| EP1807018A4 (en) * | 2004-10-21 | 2012-07-04 | Univ Iowa Res Found | SYSTEM FOR CONTROLLED IN-SITU ADMINISTRATION OF MEDICINAL PRODUCTS |
| US9227958B2 (en) * | 2006-02-03 | 2016-01-05 | Glenmark Pharmaceuticals Limited | Amorphous and crystalline forms of aprepitant and processes for the preparation thereof |
| JP2009535364A (ja) * | 2006-05-03 | 2009-10-01 | シーエヌエスバイオ ピーティーワイ リミテッド | 炎症性疼痛の治療のための方法および組成物 |
| US20070265329A1 (en) | 2006-05-12 | 2007-11-15 | Devang Shah T | Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) |
| US20100151035A1 (en) * | 2007-03-13 | 2010-06-17 | Sandoz Ag | Pharmaceutical compositions of poorly soluble drugs |
| EP3090743A1 (en) * | 2008-01-09 | 2016-11-09 | Charleston Laboratories, Inc. | Pharmaceutical compositions for treating headache and eliminating nausea |
| AU2009260469B2 (en) * | 2008-05-29 | 2014-02-13 | Albany Molecular Research, Inc. | 5-HT3 receptor modulators, methods of making, and use thereof |
| CA2767576C (en) * | 2009-07-08 | 2020-03-10 | Charleston Laboratories Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
| HUP1000325A2 (en) * | 2010-06-18 | 2012-01-30 | Druggability Technologies Ip Holdco Jersey Ltd | Nanostructured aprepitant compositions and process for their preparation |
-
2012
- 2012-07-06 HR HRP20201138TT patent/HRP20201138T1/hr unknown
- 2012-07-06 SM SM20200385T patent/SMT202000385T1/it unknown
- 2012-07-06 ES ES12756353T patent/ES2798103T3/es active Active
- 2012-07-06 HU HUE12756353A patent/HUE051147T2/hu unknown
- 2012-07-06 PL PL12756353T patent/PL2866797T3/pl unknown
- 2012-07-06 DK DK12756353.4T patent/DK2866797T3/da active
- 2012-07-06 SI SI201231807T patent/SI2866797T1/sl unknown
- 2012-07-06 EP EP12756353.4A patent/EP2866797B1/en active Active
- 2012-07-06 US US14/412,147 patent/US20150165045A1/en not_active Abandoned
- 2012-07-06 PT PT127563534T patent/PT2866797T/pt unknown
- 2012-07-06 WO PCT/EP2012/002854 patent/WO2014005606A1/en not_active Ceased
- 2012-07-06 LT LTEP12756353.4T patent/LT2866797T/lt unknown
- 2012-07-06 RS RS20200846A patent/RS60599B1/sr unknown
-
2020
- 2020-04-17 US US16/851,779 patent/US20200237920A1/en not_active Abandoned
- 2020-07-07 CY CY20201100624T patent/CY1123370T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014005606A1 (en) | 2014-01-09 |
| US20200237920A1 (en) | 2020-07-30 |
| LT2866797T (lt) | 2020-06-25 |
| HUE051147T2 (hu) | 2021-03-01 |
| SMT202000385T1 (it) | 2020-11-10 |
| PT2866797T (pt) | 2020-07-22 |
| EP2866797B1 (en) | 2020-04-29 |
| US20150165045A1 (en) | 2015-06-18 |
| HRP20201138T1 (hr) | 2020-10-30 |
| ES2798103T3 (es) | 2020-12-09 |
| CY1123370T1 (el) | 2021-12-31 |
| EP2866797A1 (en) | 2015-05-06 |
| RS60599B1 (sr) | 2020-08-31 |
| SI2866797T1 (sl) | 2020-08-31 |
| DK2866797T3 (da) | 2020-08-03 |
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