SI2849758T1 - Sestavki, ki vsebujejo zoledronsko kislino ali sorodne spojine za lajšanje vnetne bolečine in sorodnih stanj - Google Patents
Sestavki, ki vsebujejo zoledronsko kislino ali sorodne spojine za lajšanje vnetne bolečine in sorodnih stanj Download PDFInfo
- Publication number
- SI2849758T1 SI2849758T1 SI201330993T SI201330993T SI2849758T1 SI 2849758 T1 SI2849758 T1 SI 2849758T1 SI 201330993 T SI201330993 T SI 201330993T SI 201330993 T SI201330993 T SI 201330993T SI 2849758 T1 SI2849758 T1 SI 2849758T1
- Authority
- SI
- Slovenia
- Prior art keywords
- zoledronic acid
- use according
- administered
- mammal
- monthly dose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (7)
- SESTAVKI, KI VSEBUJEJO ZOLEDRONSKO KISLINO ALI SORODNE SPOJINE ZA LAJŠANJE VNETNE BOLEČINE IN SORODNIH STANJ PATENTNI ZAHTEVKI1. Zoledronska kislina za uporabo pri zdravljenju kompleksnega regionalnega sindroma bolečine pri sesalcu, kjer se oralna dozirna oblika, ki vsebuje zoledronsko kislino, daje v skupnem mesečnem odmerku zoledronske kisline, ki je približno 100 mg/m2 do približno 600 mg/m2 glede na telesno površino sesalca.
- 2. Zoledronska kislina za uporabo po zahtevku 1, kjer se mesečni odmerek lahko da kot dva ali več posameznih odmerkov, ki se dajejo v mesecu.
- 3. Zoledronska kislina za uporabo po zahtevku 1 ali zahtevku 2, pri čemer je sesalec človeško bitje in skupni mesečni odmerek zoledronske kisline 100 mg/m2 do 200 mg/m2.
- 4. Zoledronska kislina za uporabo po zahtevku 3, kjer se skupni mesečni odmerek daje v 4 do 5 tedenskih odmerkih.
- 5. Zoledronska kislina za uporabo po zahtevku 3, kjer se skupni mesečni odmerek daje v 28 do 31 dnevnih odmerkih.
- 6. Zoledronska kislina za uporabo po katerem koli od predhodnih zahtevkov, kjer je sesalec človeško bitje, ki prejme skupni tedenski odmerek zoledronske kisline, ki je 10 mg do 300 mg.
- 7. Zoledronska kislina za uporabo po katerem koli od predhodnih zahtevkov, kjer se zoledronska kislina daje kot sol dianion zoledronske kisline.
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261646538P | 2012-05-14 | 2012-05-14 | |
| US201261647478P | 2012-05-15 | 2012-05-15 | |
| US201261654292P | 2012-06-01 | 2012-06-01 | |
| US201261654383P | 2012-06-01 | 2012-06-01 | |
| US201261655527P | 2012-06-05 | 2012-06-05 | |
| US201261655541P | 2012-06-05 | 2012-06-05 | |
| US201361762225P | 2013-02-07 | 2013-02-07 | |
| US201361764563P | 2013-02-14 | 2013-02-14 | |
| US201361767676P | 2013-02-21 | 2013-02-21 | |
| US201361767647P | 2013-02-21 | 2013-02-21 | |
| US201361803721P | 2013-03-20 | 2013-03-20 | |
| EP13791356.2A EP2849758B1 (en) | 2012-05-14 | 2013-05-14 | Compositions comprising zoledronic acid or related compounds for relieving inflammatory pain and related conditions |
| PCT/US2013/040939 WO2013173330A1 (en) | 2012-05-14 | 2013-05-14 | Compositions comprising zoledronic acid or related compounds for relieving inflammatory pain and related conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2849758T1 true SI2849758T1 (sl) | 2018-07-31 |
Family
ID=49549077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201330993T SI2849758T1 (sl) | 2012-05-14 | 2013-05-14 | Sestavki, ki vsebujejo zoledronsko kislino ali sorodne spojine za lajšanje vnetne bolečine in sorodnih stanj |
Country Status (20)
| Country | Link |
|---|---|
| US (5) | US20130303488A1 (sl) |
| EP (2) | EP3323418A1 (sl) |
| JP (2) | JP2015518828A (sl) |
| KR (3) | KR20150035597A (sl) |
| CN (2) | CN104349781A (sl) |
| AU (3) | AU2013262995B2 (sl) |
| CA (2) | CA2873742C (sl) |
| CY (1) | CY1120503T1 (sl) |
| DK (1) | DK2849758T3 (sl) |
| ES (1) | ES2667535T3 (sl) |
| HK (1) | HK1255373A1 (sl) |
| HR (1) | HRP20180606T1 (sl) |
| HU (1) | HUE038905T2 (sl) |
| LT (1) | LT2849758T (sl) |
| NZ (1) | NZ702414A (sl) |
| PL (1) | PL2849758T3 (sl) |
| PT (1) | PT2849758T (sl) |
| RS (1) | RS57294B1 (sl) |
| SI (1) | SI2849758T1 (sl) |
| WO (1) | WO2013173330A1 (sl) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| SI2459176T1 (sl) | 2009-07-31 | 2018-01-31 | Gruenenthal Gmbh | Kristalizacijski postopek in biološka uporabnost |
| US9340565B2 (en) | 2010-11-24 | 2016-05-17 | Thar Pharmaceuticals, Inc. | Crystalline forms |
| US9925203B2 (en) | 2012-05-14 | 2018-03-27 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US9616078B2 (en) | 2012-05-14 | 2017-04-11 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
| US9867839B2 (en) | 2012-05-14 | 2018-01-16 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
| US8802658B2 (en) | 2012-05-14 | 2014-08-12 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
| US20140349974A1 (en) * | 2014-08-12 | 2014-11-27 | Antecip Bioventures Ii Llc | Zoledronic acid dosage forms for the treatment of pain |
| US9700570B2 (en) | 2014-05-27 | 2017-07-11 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9820999B2 (en) | 2012-05-14 | 2017-11-21 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US9211257B2 (en) | 2012-05-14 | 2015-12-15 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US9949993B2 (en) | 2012-05-14 | 2018-04-24 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US10016445B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10092581B2 (en) | 2014-05-15 | 2018-10-09 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
| US9717747B2 (en) | 2012-05-14 | 2017-08-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US9827256B2 (en) | 2014-05-27 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating lower back pain |
| US10413561B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
| US9877977B2 (en) | 2012-05-14 | 2018-01-30 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10493085B2 (en) | 2012-05-14 | 2019-12-03 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
| WO2015184003A1 (en) * | 2014-05-27 | 2015-12-03 | Antecip Bioventures Ii Llp | Osteoclast inhibitors for pain |
| US9694023B2 (en) | 2012-05-14 | 2017-07-04 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
| US9289441B2 (en) | 2014-08-08 | 2016-03-22 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
| US9956234B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
| US9707245B2 (en) | 2012-05-14 | 2017-07-18 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US10028969B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9789128B2 (en) | 2012-05-14 | 2017-10-17 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9827192B2 (en) | 2012-05-14 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9782421B1 (en) | 2012-05-14 | 2017-10-10 | Antecip Bioventures Ii Llc | Neridronic acid molecular complex for treating complex regional pain syndrome |
| US10173986B2 (en) | 2012-05-14 | 2019-01-08 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
| US9675626B2 (en) | 2012-05-14 | 2017-06-13 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10039773B2 (en) | 2012-05-14 | 2018-08-07 | Antecip Bioventures Ii Llc | Neridronic acid for treating arthritis |
| US10111837B2 (en) | 2012-05-14 | 2018-10-30 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds |
| US10028908B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9895383B2 (en) * | 2012-05-14 | 2018-02-20 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10034890B2 (en) | 2012-05-14 | 2018-07-31 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US8865757B1 (en) | 2014-05-28 | 2014-10-21 | Antecip Bioventures Ii Llp | Therapeutic compositions comprising imidazole and imidazolium compounds |
| US9943531B2 (en) | 2014-08-08 | 2018-04-17 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
| US9956238B2 (en) | 2014-05-15 | 2018-05-01 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US9795622B2 (en) | 2012-05-14 | 2017-10-24 | Antecip Bioventures Ii Llc | Neridronic acid for treating pain associated with a joint |
| US9999629B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9901589B2 (en) | 2012-05-14 | 2018-02-27 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9956237B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US10463682B2 (en) | 2012-05-14 | 2019-11-05 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating low back pain |
| US10413560B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
| US10080765B2 (en) | 2012-05-14 | 2018-09-25 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US10016446B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating Paget's disease of bone |
| US10350227B2 (en) | 2012-05-14 | 2019-07-16 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US9669040B2 (en) | 2012-05-14 | 2017-06-06 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9844559B2 (en) | 2012-05-14 | 2017-12-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating bone marrow lesions |
| US9999628B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US9867840B2 (en) | 2014-05-27 | 2018-01-16 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10004756B2 (en) | 2014-05-15 | 2018-06-26 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9662343B2 (en) | 2012-05-14 | 2017-05-30 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US11654152B2 (en) | 2012-05-14 | 2023-05-23 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
| US9861648B2 (en) | 2012-05-14 | 2018-01-09 | Antecip Boiventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US9707247B2 (en) | 2012-05-14 | 2017-07-18 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US9427403B2 (en) | 2012-05-14 | 2016-08-30 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
| US9770457B2 (en) | 2012-05-14 | 2017-09-26 | Antecip Bioventures Ii Llc | Neridronic acid for treating bone marrow lesion |
| US9655908B2 (en) | 2012-05-14 | 2017-05-23 | Antecip Bioventures Ii Llc | Neridronic acid molecular complex for treating complex regional pain syndrome |
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| CN108434154A (zh) * | 2013-10-25 | 2018-08-24 | 安泰赛普生物风投二代有限责任公司 | 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物 |
| CN106456610A (zh) * | 2014-05-27 | 2017-02-22 | 安泰赛普生物风投二代有限责任公司 | 用于疼痛的破骨细胞抑制剂 |
| US20170182072A1 (en) * | 2014-05-27 | 2017-06-29 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| NZ726690A (en) * | 2014-05-27 | 2018-03-23 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for pain |
| US9127069B1 (en) | 2014-06-11 | 2015-09-08 | Antecip Bioventures LLC | Compositions comprising rank/rankl antagonists and related compounds for treating pain |
| CA3114271C (en) * | 2014-05-27 | 2023-06-06 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for pain |
| US9079927B1 (en) | 2014-05-27 | 2015-07-14 | Antecip Bioventures Ii Llc | Substituted imidazolium compounds for treating disease |
| US9688765B2 (en) | 2014-06-11 | 2017-06-27 | Antecip Bioventures Ii Llc | Methods using RANK/RANKL antagonist antibodies for treating pain |
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| WO2017208070A1 (en) | 2016-05-31 | 2017-12-07 | Grünenthal GmbH | Bisphosphonic acid and coformers with lysin, glycin, nicotinamide for treating psoriatic arthritis |
| US20190328755A1 (en) * | 2018-04-30 | 2019-10-31 | Grunenthal Gmbh | Methods of treating complex regional pain syndrome (crps) or symptoms comprising administration of neridronic acid |
| CN109908159B (zh) * | 2019-03-15 | 2021-12-07 | 暨南大学 | 唑来膦酸和有机硒化合物联用在制备抗肿瘤药物中的应用 |
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-
2013
- 2013-05-14 US US13/894,274 patent/US20130303488A1/en not_active Abandoned
- 2013-05-14 HU HUE13791356A patent/HUE038905T2/hu unknown
- 2013-05-14 KR KR1020147034760A patent/KR20150035597A/ko active Application Filing
- 2013-05-14 KR KR1020197000076A patent/KR20190004381A/ko not_active Application Discontinuation
- 2013-05-14 KR KR1020167032879A patent/KR20160139050A/ko not_active Application Discontinuation
- 2013-05-14 PT PT137913562T patent/PT2849758T/pt unknown
- 2013-05-14 LT LTEP13791356.2T patent/LT2849758T/lt unknown
- 2013-05-14 ES ES13791356.2T patent/ES2667535T3/es active Active
- 2013-05-14 WO PCT/US2013/040939 patent/WO2013173330A1/en active Application Filing
- 2013-05-14 EP EP17206293.7A patent/EP3323418A1/en active Pending
- 2013-05-14 US US13/894,252 patent/US20130303486A1/en not_active Abandoned
- 2013-05-14 SI SI201330993T patent/SI2849758T1/sl unknown
- 2013-05-14 CA CA2873742A patent/CA2873742C/en active Active
- 2013-05-14 JP JP2015512753A patent/JP2015518828A/ja active Pending
- 2013-05-14 CA CA2987470A patent/CA2987470A1/en not_active Abandoned
- 2013-05-14 PL PL13791356T patent/PL2849758T3/pl unknown
- 2013-05-14 RS RS20180483A patent/RS57294B1/sr unknown
- 2013-05-14 CN CN201380025570.XA patent/CN104349781A/zh active Pending
- 2013-05-14 US US13/894,244 patent/US20130303485A1/en not_active Abandoned
- 2013-05-14 EP EP13791356.2A patent/EP2849758B1/en active Active
- 2013-05-14 NZ NZ702414A patent/NZ702414A/en unknown
- 2013-05-14 CN CN201811173434.6A patent/CN109331027A/zh active Pending
- 2013-05-14 AU AU2013262995A patent/AU2013262995B2/en active Active
- 2013-05-14 DK DK13791356.2T patent/DK2849758T3/en active
- 2013-05-14 US US13/894,262 patent/US20130303487A1/en not_active Abandoned
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2016
- 2016-02-03 US US15/014,994 patent/US20160151398A1/en not_active Abandoned
- 2016-11-08 AU AU2016256701A patent/AU2016256701B2/en active Active
-
2018
- 2018-04-11 JP JP2018075822A patent/JP2018127477A/ja active Pending
- 2018-04-17 HR HRP20180606TT patent/HRP20180606T1/hr unknown
- 2018-05-03 CY CY20181100458T patent/CY1120503T1/el unknown
- 2018-08-10 AU AU2018214132A patent/AU2018214132B2/en active Active
- 2018-11-14 HK HK18114512.0A patent/HK1255373A1/zh unknown
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