SI2729143T1 - Uporaba biotina za zdravljenje multiple skleroze - Google Patents
Uporaba biotina za zdravljenje multiple sklerozeInfo
- Publication number
- SI2729143T1 SI2729143T1 SI201330023T SI201330023T SI2729143T1 SI 2729143 T1 SI2729143 T1 SI 2729143T1 SI 201330023 T SI201330023 T SI 201330023T SI 201330023 T SI201330023 T SI 201330023T SI 2729143 T1 SI2729143 T1 SI 2729143T1
- Authority
- SI
- Slovenia
- Prior art keywords
- biotin
- treatment
- multiple sclerosis
- sclerosis
- Prior art date
Links
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 title 2
- 229960002685 biotin Drugs 0.000 title 1
- 235000020958 biotin Nutrition 0.000 title 1
- 239000011616 biotin Substances 0.000 title 1
- 201000006417 multiple sclerosis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1257254A FR2993780B1 (fr) | 2012-07-26 | 2012-07-26 | Methode de traitement de la sclerose en plaque |
| US13/644,615 US8835487B2 (en) | 2012-07-26 | 2012-10-04 | Method of treating multiple sclerosis |
| PCT/EP2013/058936 WO2014016003A1 (en) | 2012-07-26 | 2013-04-29 | Use of biotin for the treatment of multiple sclerosis |
| EP13719836.2A EP2729143B1 (en) | 2012-07-26 | 2013-04-29 | Use of biotin for the treatment of multiple sclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2729143T1 true SI2729143T1 (sl) | 2015-05-29 |
Family
ID=47294963
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201330023T SI2729143T1 (sl) | 2012-07-26 | 2013-04-29 | Uporaba biotina za zdravljenje multiple skleroze |
| SI201331768T SI2857019T1 (sl) | 2012-07-26 | 2013-04-29 | Postopek zdravljenja multiple skleroze |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201331768T SI2857019T1 (sl) | 2012-07-26 | 2013-04-29 | Postopek zdravljenja multiple skleroze |
Country Status (25)
| Country | Link |
|---|---|
| US (5) | US8835487B2 (enExample) |
| EP (2) | EP2729143B1 (enExample) |
| JP (1) | JP6208235B2 (enExample) |
| KR (1) | KR101967502B1 (enExample) |
| CN (2) | CN104602689A (enExample) |
| AU (1) | AU2013295370B2 (enExample) |
| BR (1) | BR112015001562A2 (enExample) |
| CA (1) | CA2879434C (enExample) |
| CY (1) | CY1116304T1 (enExample) |
| DK (2) | DK2729143T3 (enExample) |
| EA (1) | EA030478B1 (enExample) |
| ES (3) | ES2811074T3 (enExample) |
| FR (1) | FR2993780B1 (enExample) |
| HK (1) | HK1207583A1 (enExample) |
| HR (1) | HRP20150260T1 (enExample) |
| HU (1) | HUE024558T2 (enExample) |
| IL (1) | IL236790A (enExample) |
| LT (1) | LT2857019T (enExample) |
| ME (1) | ME02060B (enExample) |
| PL (1) | PL2729143T3 (enExample) |
| PT (2) | PT2729143E (enExample) |
| RS (1) | RS53893B1 (enExample) |
| SI (2) | SI2729143T1 (enExample) |
| SM (1) | SMT201500057B (enExample) |
| WO (1) | WO2014016003A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2958166B1 (fr) * | 2010-04-06 | 2012-07-13 | Assist Publ Hopitaux De Paris | Compositions pharmaceutiques fortement dosees en biotine |
| FR2993780B1 (fr) | 2012-07-26 | 2015-02-13 | Assist Publ Hopitaux De Paris | Methode de traitement de la sclerose en plaque |
| US9789092B2 (en) | 2013-04-29 | 2017-10-17 | Assistance Publique—Hopitaux de Paris | Biotin for use in treating X-linked adrenoleukodystrophy |
| EP3257881B1 (en) * | 2015-02-13 | 2020-09-02 | Unimatec Co., Ltd. | Fluorinated copolymer, and surface modifier containing same as active ingredient |
| EP3072513A1 (en) * | 2015-03-26 | 2016-09-28 | Medday | Biotin for treating Amyotrophic lateral sclerosis |
| US20170135969A1 (en) | 2015-11-12 | 2017-05-18 | Jds Therapeutics, Llc | Topical arginine-silicate-inositol for wound healing |
| WO2017086835A1 (ru) * | 2015-11-17 | 2017-05-26 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция, обладающая терапевтическим эффектом в отношении демиелинизирующих заболеваний (варианты) |
| RU2638803C2 (ru) * | 2016-06-09 | 2017-12-15 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Таблетки биотина с замедленным высвобождением и способ их получения |
| RU2611415C1 (ru) * | 2015-11-17 | 2017-02-21 | Общество С Ограниченной Ответственностью "Валента - Интеллект" | ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ ТЕРАПЕВТИЧЕСКИМ ЭФФЕКТОМ В ОТНОШЕНИИ ДЕМИЕЛИНИЗИРУЮЩИХ ЗАБОЛЕВАНИЙ (Варианты) |
| EP3275439A1 (en) | 2016-07-29 | 2018-01-31 | Medday Pharmaceuticals | Method for treating hepatic encephalopathy |
| CA3035584A1 (en) | 2016-09-01 | 2018-03-08 | Jds Therapeutics, Llc | Magnesium biotinate compositions and methods of use |
| RU2639488C1 (ru) * | 2017-04-06 | 2017-12-21 | Общество С Ограниченной Ответственностью "Валента - Интеллект" | Фармацевтическая композиция, содержащая биотин, и способ ее получения |
| WO2020102203A1 (en) * | 2018-11-13 | 2020-05-22 | Jds Therapeutics, Llc | Treatment of autoimmune disorders, such as relapsing remitting multiple sclerosis and clinically isolated syndrome with biotin compositions |
| CN112076310A (zh) * | 2019-06-14 | 2020-12-15 | 苏州融析生物科技有限公司 | 一种治疗多发性硬化的药物组合物及其制备 |
| EP4076413A1 (en) | 2019-12-16 | 2022-10-26 | Nutrition 21, LLC | Methods of production of arginine-silicate complexes |
| PH12022551124A1 (en) | 2020-01-01 | 2023-08-23 | Celagenex Res India Pvt Ltd | Synergistic nutritional compositions for enhancing atp efficiency |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3609165A (en) | 1968-07-19 | 1971-09-28 | Research Corp | 1,3-diazabicyclo {8 3.1.0{9 {0 hex-3-enes |
| JPH0995448A (ja) | 1995-09-29 | 1997-04-08 | Calpis Food Ind Co Ltd:The | 血中ビオチン濃度の増加方法およびビオチン含有飲食品 |
| EP0891719A1 (en) * | 1997-07-14 | 1999-01-20 | N.V. Nutricia | Nutritional composition containing methionine |
| US5789401A (en) | 1997-08-08 | 1998-08-04 | Nutrition 21 | High-dose chromium/biotin treatment of type II diabetes |
| US6664039B1 (en) | 1998-10-14 | 2003-12-16 | California Institute Of Technology | Methods and compositions for modulating neurodegeneration |
| UA73492C2 (en) * | 1999-01-19 | 2005-08-15 | Aromatic heterocyclic compounds as antiinflammatory agents | |
| DE19903241A1 (de) | 1999-01-28 | 2000-08-03 | Merck Patent Gmbh | Galenische Formulierung |
| EP1536698A1 (en) | 2002-08-23 | 2005-06-08 | DSM IP Assets B.V. | Novel nutraceutical compositions comprising biotin |
| JP4496078B2 (ja) | 2002-09-30 | 2010-07-07 | 第一三共株式会社 | パンテチン含有粒状物 |
| DE10341240A1 (de) * | 2003-09-08 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Substituierte Thienoimidazole, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US20050142124A1 (en) * | 2003-12-31 | 2005-06-30 | Kaiser Jon D. | Nutrient compositions and methods for enhanced effectiveness of the immune system |
| IL162288A0 (en) * | 2004-06-01 | 2005-11-20 | Future Products Man S A | Compositions and methods for treating neurodegenerative disorders |
| BG66011B1 (bg) * | 2005-05-25 | 2010-10-29 | Райна Щонова | Състав от растителен произход |
| US20130004545A1 (en) | 2009-12-23 | 2013-01-03 | Lupin Limited | Slow release pharmaceutical compositions of iloperidone |
| FR2958166B1 (fr) * | 2010-04-06 | 2012-07-13 | Assist Publ Hopitaux De Paris | Compositions pharmaceutiques fortement dosees en biotine |
| FR2993780B1 (fr) | 2012-07-26 | 2015-02-13 | Assist Publ Hopitaux De Paris | Methode de traitement de la sclerose en plaque |
-
2012
- 2012-07-26 FR FR1257254A patent/FR2993780B1/fr not_active Expired - Fee Related
- 2012-10-04 US US13/644,615 patent/US8835487B2/en active Active
-
2013
- 2013-04-29 ES ES14194213T patent/ES2811074T3/es active Active
- 2013-04-29 DK DK13719836.2T patent/DK2729143T3/en active
- 2013-04-29 HU HUE13719836A patent/HUE024558T2/hu unknown
- 2013-04-29 EP EP13719836.2A patent/EP2729143B1/en active Active
- 2013-04-29 RS RS20150168A patent/RS53893B1/sr unknown
- 2013-04-29 PT PT13719836T patent/PT2729143E/pt unknown
- 2013-04-29 SI SI201330023T patent/SI2729143T1/sl unknown
- 2013-04-29 WO PCT/EP2013/058936 patent/WO2014016003A1/en not_active Ceased
- 2013-04-29 EP EP14194213.6A patent/EP2857019B1/en active Active
- 2013-04-29 SI SI201331768T patent/SI2857019T1/sl unknown
- 2013-04-29 PL PL13719836T patent/PL2729143T3/pl unknown
- 2013-04-29 EA EA201590270A patent/EA030478B1/ru not_active IP Right Cessation
- 2013-04-29 HR HRP20150260TT patent/HRP20150260T1/hr unknown
- 2013-04-29 CN CN201380039687.3A patent/CN104602689A/zh active Pending
- 2013-04-29 HK HK15108330.5A patent/HK1207583A1/xx unknown
- 2013-04-29 ES ES13719836.2T patent/ES2532364T3/es active Active
- 2013-04-29 AU AU2013295370A patent/AU2013295370B2/en not_active Ceased
- 2013-04-29 BR BR112015001562A patent/BR112015001562A2/pt not_active Application Discontinuation
- 2013-04-29 KR KR1020157004516A patent/KR101967502B1/ko not_active Expired - Fee Related
- 2013-04-29 CA CA2879434A patent/CA2879434C/en not_active Expired - Fee Related
- 2013-04-29 ME MEP-2015-32A patent/ME02060B/me unknown
- 2013-04-29 DK DK14194213.6T patent/DK2857019T3/da active
- 2013-04-29 JP JP2015523453A patent/JP6208235B2/ja not_active Expired - Fee Related
- 2013-04-29 CN CN201910026016.2A patent/CN109908140A/zh active Pending
- 2013-04-29 PT PT141942136T patent/PT2857019T/pt unknown
- 2013-04-29 LT LTEP14194213.6T patent/LT2857019T/lt unknown
-
2014
- 2014-01-14 ES ES14700423.8T patent/ES2626079T3/es active Active
- 2014-08-13 US US14/458,625 patent/US9351961B2/en not_active Expired - Fee Related
-
2015
- 2015-01-19 IL IL236790A patent/IL236790A/en active IP Right Grant
- 2015-03-09 SM SM201500057T patent/SMT201500057B/xx unknown
- 2015-03-11 CY CY20151100243T patent/CY1116304T1/el unknown
-
2016
- 2016-04-12 US US15/096,957 patent/US10201528B2/en not_active Expired - Fee Related
-
2018
- 2018-12-21 US US16/231,073 patent/US20190117625A1/en not_active Abandoned
- 2018-12-21 US US16/231,111 patent/US20190117626A1/en not_active Abandoned
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