CN109908140A - 生物素治疗多发性硬化的用途 - Google Patents
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
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- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR12/57254 | 2012-07-26 | ||
| FR1257254A FR2993780B1 (fr) | 2012-07-26 | 2012-07-26 | Methode de traitement de la sclerose en plaque |
| US13/644,615 | 2012-10-04 | ||
| US13/644,615 US8835487B2 (en) | 2012-07-26 | 2012-10-04 | Method of treating multiple sclerosis |
| CN201380039687.3A CN104602689A (zh) | 2012-07-26 | 2013-04-29 | 生物素治疗多发性硬化的用途 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380039687.3A Division CN104602689A (zh) | 2012-07-26 | 2013-04-29 | 生物素治疗多发性硬化的用途 |
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| CN109908140A true CN109908140A (zh) | 2019-06-21 |
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Family Applications (2)
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| CN201910026016.2A Pending CN109908140A (zh) | 2012-07-26 | 2013-04-29 | 生物素治疗多发性硬化的用途 |
| CN201380039687.3A Pending CN104602689A (zh) | 2012-07-26 | 2013-04-29 | 生物素治疗多发性硬化的用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380039687.3A Pending CN104602689A (zh) | 2012-07-26 | 2013-04-29 | 生物素治疗多发性硬化的用途 |
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| Country | Link |
|---|---|
| US (5) | US8835487B2 (enExample) |
| EP (2) | EP2857019B1 (enExample) |
| JP (1) | JP6208235B2 (enExample) |
| KR (1) | KR101967502B1 (enExample) |
| CN (2) | CN109908140A (enExample) |
| AU (1) | AU2013295370B2 (enExample) |
| BR (1) | BR112015001562A2 (enExample) |
| CA (1) | CA2879434C (enExample) |
| CY (1) | CY1116304T1 (enExample) |
| DK (2) | DK2729143T3 (enExample) |
| EA (1) | EA030478B1 (enExample) |
| ES (3) | ES2532364T3 (enExample) |
| FR (1) | FR2993780B1 (enExample) |
| HK (1) | HK1207583A1 (enExample) |
| HR (1) | HRP20150260T1 (enExample) |
| HU (1) | HUE024558T2 (enExample) |
| IL (1) | IL236790A (enExample) |
| LT (1) | LT2857019T (enExample) |
| ME (1) | ME02060B (enExample) |
| PL (1) | PL2729143T3 (enExample) |
| PT (2) | PT2857019T (enExample) |
| RS (1) | RS53893B1 (enExample) |
| SI (2) | SI2857019T1 (enExample) |
| SM (1) | SMT201500057B (enExample) |
| WO (1) | WO2014016003A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2958166B1 (fr) * | 2010-04-06 | 2012-07-13 | Assist Publ Hopitaux De Paris | Compositions pharmaceutiques fortement dosees en biotine |
| FR2993780B1 (fr) | 2012-07-26 | 2015-02-13 | Assist Publ Hopitaux De Paris | Methode de traitement de la sclerose en plaque |
| WO2014177286A1 (en) | 2013-04-29 | 2014-11-06 | Assistance Publique - Hopitaux De Paris | Biotin for use in treating x-linked adrenoleukodystrophy |
| WO2016129362A1 (ja) * | 2015-02-13 | 2016-08-18 | ユニマテック株式会社 | 含フッ素共重合体およびこれを有効成分とする表面改質剤 |
| EP3072513A1 (en) | 2015-03-26 | 2016-09-28 | Medday | Biotin for treating Amyotrophic lateral sclerosis |
| US20170135969A1 (en) | 2015-11-12 | 2017-05-18 | Jds Therapeutics, Llc | Topical arginine-silicate-inositol for wound healing |
| WO2017086835A1 (ru) * | 2015-11-17 | 2017-05-26 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция, обладающая терапевтическим эффектом в отношении демиелинизирующих заболеваний (варианты) |
| RU2611415C1 (ru) * | 2015-11-17 | 2017-02-21 | Общество С Ограниченной Ответственностью "Валента - Интеллект" | ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ ТЕРАПЕВТИЧЕСКИМ ЭФФЕКТОМ В ОТНОШЕНИИ ДЕМИЕЛИНИЗИРУЮЩИХ ЗАБОЛЕВАНИЙ (Варианты) |
| RU2638803C2 (ru) * | 2016-06-09 | 2017-12-15 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Таблетки биотина с замедленным высвобождением и способ их получения |
| EP3275439A1 (en) | 2016-07-29 | 2018-01-31 | Medday Pharmaceuticals | Method for treating hepatic encephalopathy |
| CA3035584A1 (en) * | 2016-09-01 | 2018-03-08 | Jds Therapeutics, Llc | Magnesium biotinate compositions and methods of use |
| RU2639488C1 (ru) * | 2017-04-06 | 2017-12-21 | Общество С Ограниченной Ответственностью "Валента - Интеллект" | Фармацевтическая композиция, содержащая биотин, и способ ее получения |
| WO2020102203A1 (en) * | 2018-11-13 | 2020-05-22 | Jds Therapeutics, Llc | Treatment of autoimmune disorders, such as relapsing remitting multiple sclerosis and clinically isolated syndrome with biotin compositions |
| CN112076310A (zh) * | 2019-06-14 | 2020-12-15 | 苏州融析生物科技有限公司 | 一种治疗多发性硬化的药物组合物及其制备 |
| EP4076413A1 (en) | 2019-12-16 | 2022-10-26 | Nutrition 21, LLC | Methods of production of arginine-silicate complexes |
| CA3157712C (en) | 2020-01-01 | 2024-01-23 | Jotiram PALKAR | Synergistic nutritional compositions for enhancing atp efficiency |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BG109164A (bg) * | 2005-05-25 | 2006-11-30 | Райна Щонова | Състав от растителен произход |
| WO2011124571A1 (fr) * | 2010-04-06 | 2011-10-13 | Assistance Publique - Hopitaux De Paris | Compositions pharmaceutiques fortement dosees en biotine |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3609165A (en) | 1968-07-19 | 1971-09-28 | Research Corp | 1,3-diazabicyclo {8 3.1.0{9 {0 hex-3-enes |
| JPH0995448A (ja) | 1995-09-29 | 1997-04-08 | Calpis Food Ind Co Ltd:The | 血中ビオチン濃度の増加方法およびビオチン含有飲食品 |
| EP0891719A1 (en) * | 1997-07-14 | 1999-01-20 | N.V. Nutricia | Nutritional composition containing methionine |
| US5789401A (en) | 1997-08-08 | 1998-08-04 | Nutrition 21 | High-dose chromium/biotin treatment of type II diabetes |
| US6664039B1 (en) | 1998-10-14 | 2003-12-16 | California Institute Of Technology | Methods and compositions for modulating neurodegeneration |
| UA73492C2 (en) * | 1999-01-19 | 2005-08-15 | Aromatic heterocyclic compounds as antiinflammatory agents | |
| DE19903241A1 (de) | 1999-01-28 | 2000-08-03 | Merck Patent Gmbh | Galenische Formulierung |
| CN1313030C (zh) | 2002-08-23 | 2007-05-02 | 帝斯曼知识产权资产管理有限公司 | 包含生物素的新颖的营养药物性组合物 |
| CA2501021C (en) | 2002-09-30 | 2011-02-22 | Daiichi Pharmaceutical Co., Ltd. | Pantethine-containing particulate |
| DE10341240A1 (de) * | 2003-09-08 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Substituierte Thienoimidazole, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US20050142124A1 (en) * | 2003-12-31 | 2005-06-30 | Kaiser Jon D. | Nutrient compositions and methods for enhanced effectiveness of the immune system |
| IL162288A0 (en) * | 2004-06-01 | 2005-11-20 | Future Products Man S A | Compositions and methods for treating neurodegenerative disorders |
| BR112012015084A2 (pt) | 2009-12-23 | 2017-03-07 | Lupin Ltd | composição farmacêutica de liberação lenta de iloperidone |
| FR2993780B1 (fr) | 2012-07-26 | 2015-02-13 | Assist Publ Hopitaux De Paris | Methode de traitement de la sclerose en plaque |
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- 2013-04-29 SI SI201331768T patent/SI2857019T1/sl unknown
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BG109164A (bg) * | 2005-05-25 | 2006-11-30 | Райна Щонова | Състав от растителен произход |
| WO2011124571A1 (fr) * | 2010-04-06 | 2011-10-13 | Assistance Publique - Hopitaux De Paris | Compositions pharmaceutiques fortement dosees en biotine |
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| M.ANAGNOSTOULI等: "1-31-03 Biotin in CSF and serum in patients with multiple sclerosis", 《JOURNAL OF THE NEUROLOGICAL SCIENCES》 * |
| 刘焯霖等: "《神经遗传病学》", 30 April 2002, 人民卫生出版社 * |
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