SI2432884T1 - Plazmid brez antibiotika - Google Patents

Plazmid brez antibiotika

Info

Publication number
SI2432884T1
SI2432884T1 SI201031305A SI201031305A SI2432884T1 SI 2432884 T1 SI2432884 T1 SI 2432884T1 SI 201031305 A SI201031305 A SI 201031305A SI 201031305 A SI201031305 A SI 201031305A SI 2432884 T1 SI2432884 T1 SI 2432884T1
Authority
SI
Slovenia
Prior art keywords
antibiotic
free plasmid
plasmid
free
Prior art date
Application number
SI201031305A
Other languages
English (en)
Inventor
Jean-Christophe Audonnet
Edmond Jolivet
Original Assignee
Merial, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial, Inc. filed Critical Merial, Inc.
Publication of SI2432884T1 publication Critical patent/SI2432884T1/sl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/73Expression systems using phage (lambda) regulatory sequences
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/106Plasmid DNA for vertebrates
    • C12N2800/107Plasmid DNA for vertebrates for mammalian
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/24Vectors characterised by the absence of particular element, e.g. selectable marker, viral origin of replication

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI201031305A 2009-05-22 2010-05-24 Plazmid brez antibiotika SI2432884T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18075509P 2009-05-22 2009-05-22
PCT/US2010/035979 WO2010135742A1 (en) 2009-05-22 2010-05-24 Antibiotic-free plasmid
EP10720510.6A EP2432884B1 (en) 2009-05-22 2010-05-24 Antibiotic-free plasmid

Publications (1)

Publication Number Publication Date
SI2432884T1 true SI2432884T1 (sl) 2016-11-30

Family

ID=42342694

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201031305A SI2432884T1 (sl) 2009-05-22 2010-05-24 Plazmid brez antibiotika

Country Status (19)

Country Link
US (2) US9217153B2 (sl)
EP (2) EP3124613B1 (sl)
JP (2) JP5918125B2 (sl)
KR (1) KR101719833B1 (sl)
AU (1) AU2010249325B2 (sl)
BR (1) BRPI1011048B1 (sl)
CA (1) CA2761964C (sl)
DK (1) DK2432884T3 (sl)
ES (1) ES2600612T3 (sl)
HR (1) HRP20161397T1 (sl)
HU (1) HUE031597T2 (sl)
LT (1) LT2432884T (sl)
MX (1) MX2011012234A (sl)
NZ (1) NZ596453A (sl)
PL (1) PL2432884T3 (sl)
PT (1) PT2432884T (sl)
RU (1) RU2548809C2 (sl)
SI (1) SI2432884T1 (sl)
WO (1) WO2010135742A1 (sl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2642138T3 (es) 2011-12-21 2017-11-15 Bionet-Asia Co. Ltd Cepas de Bordetella pertussis modificadas
US10208093B2 (en) * 2013-12-16 2019-02-19 Agricultural Technology Research Institute Plasmid, method and kit thereof for producing heat labile enterotoxin B-subunit
BR112017001463A2 (pt) * 2014-07-25 2018-02-20 Delphi Genetics célula hospedeira melhorada para produzir proteínas
AU2017353323B2 (en) 2016-11-01 2024-02-29 Novo Nordisk A/S Tolerogenic DNA vaccine
RU2705252C1 (ru) * 2018-06-08 2019-11-06 Селл энд Джин Терапи Лтд Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген CFTR, или NOS1, или AQ1, или AQ3, или AQ5, для лечения заболеваний, связанных с необходимостью повышения уровня экспрессии этих целевых генов, способ его получения и использования, штамм Escherichia coli SCS110-AF/VTvaf17-CFTR, или Escherichia coli SCS110-AF/VTvaf17-NOS1, или Escherichia coli SCS110-AF/VTvaf17-AQ1, или Escherichia coli SCS110-AF/VTvaf17-AQ3, или Escherichia coli SCS110-AF/VTvaf17-AQ5, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора
RU2712838C1 (ru) * 2018-09-04 2020-01-31 Генетик Диагностик Энд Терапи 21 Лтд Генотерапевтический ДНК-вектор GDTT1.8NAS12, способ его получения, штамм Escherichia coli JM110-NAS, способ его получения, штамм Escherichia coli JM110-NAS/GDTT1.8NAS12, несущий генотерапевтический ДНК-вектор GDTT1.8NAS12, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора
RU2707537C1 (ru) * 2018-09-04 2019-11-27 Общество с ограниченной ответственностью "Аллель Центр Инновационных Биотехнологий" Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген, выбранный из группы генов COL1A1, COL1A2, BMP2, BMP7, для повышения уровня экспрессии этих целевых генов, способ его получения и применения, штамм Escherichia coli SCS110-AF/VTvaf17- COL1A1 или Escherichia coli SCS110-AF/VTvaf17- COL1A2 или Escherichia coli SCS110-AF/VTvaf17- BMP2 или Escherichia coli SCS110-AF/VTvaf17- BMP7, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора
RU2705256C1 (ru) * 2018-09-05 2019-11-06 Общество С Ограниченной Ответственностью "Прорывные Инновационные Технологии" Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген, выбранный из группы генов SKI, TGFB3, TIMP2, FMOD для повышения уровня экспрессии этих целевых генов, способ его получения и применения, штамм Escherichia coli SCS110-AF/VTvaf17-SKI или Escherichia coli SCS110-AF/VTvaf17-TGFB3 или Escherichia coli SCS110-AF/VTvaf17-TIMP2 или Escherichia coli SCS110-AF/VTvaf17-FMOD, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора
RU2730664C2 (ru) * 2018-12-27 2020-08-24 Селл энд Джин Терапи Лтд Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген, выбранный из группы генов ANG, ANGPT1, VEGFA, FGF1, HIF1α, HGF, SDF1, KLK4, PDGFC, PROK1, PROK2 для повышения уровня экспрессии этих целевых генов, способ его получения и применения, штамм Escherichia coli SCS110-AF/VTvaf17-ANG, или Escherichia coli SCS110-AF/VTvaf17-ANGPT1, или Escherichia coli SCS110-AF/VTvaf17-VEGFA, или Escherichia coli SCS110-AF/VTvaf17-FGF1, или Escherichia coli SCS110-AF/VTvaf17-HIF1α, или Escherichia coli SCS110-AF/VTvaf17-HGF, или Escherichia coli SCS110-AF/VTvaf17-SDF1, или Escherichia coli SCS110-AF/VTvaf17-KLK4, или Escherichia coli SCS110-AF/VTvaf17-PDGFC, или Escherichia coli SCS110-AF/VTvaf17-PROK1, или Escherichia coli SCS110-AF/VTvaf17-PROK2, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора
RU2715314C1 (ru) * 2019-01-25 2020-02-26 Селл энд Джин Терапи Лтд Генотерапевтический ДНК-вектор VTvaf17-Act1-Cas9 на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген Cas9, для гетерологичной экспрессии этого целевого гена в клетках растений при геномном редактировании растений, способ получения и применения генотерапевтического ДНК-вектора, штамм Escherichia coli SCS110-AF/VTvaf17-Act1-Cas9, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора
US11279745B2 (en) 2019-04-26 2022-03-22 Novo Nordisk A/S Tolerogenic DNA vaccine
US20230203536A1 (en) 2020-05-28 2023-06-29 Consejo Superior De Investigaciones Científicas (Csic) Coronavirus rna replicons and use thereof as vaccines
EP4019539A1 (en) * 2020-12-22 2022-06-29 Consejo Superior de Investigaciones Científicas (CSIC) Recombinant bacterium and uses thereof
WO2023094595A1 (en) 2021-11-26 2023-06-01 Consejo Superior De Investigaciones Científicas Coronavirus derived rna replicons and their use as vaccines
WO2024096123A1 (ja) * 2022-11-04 2024-05-10 株式会社バイオパレット 遺伝子が改変された微生物およびその生産方法

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Also Published As

Publication number Publication date
CA2761964C (en) 2018-11-27
LT2432884T (lt) 2016-11-10
EP2432884A1 (en) 2012-03-28
DK2432884T3 (en) 2016-08-22
AU2010249325A1 (en) 2011-12-08
CA2761964A1 (en) 2010-11-25
NZ596453A (en) 2013-09-27
ES2600612T3 (es) 2017-02-10
US20100298419A1 (en) 2010-11-25
PL2432884T3 (pl) 2017-01-31
BRPI1011048B1 (pt) 2019-01-29
JP2015221050A (ja) 2015-12-10
EP3124613A1 (en) 2017-02-01
HRP20161397T1 (hr) 2016-12-16
US20160312231A1 (en) 2016-10-27
EP3124613B1 (en) 2020-03-11
RU2011152377A (ru) 2013-06-27
US10487334B2 (en) 2019-11-26
EP2432884B1 (en) 2016-08-03
RU2548809C2 (ru) 2015-04-20
JP5918125B2 (ja) 2016-05-18
KR20120016661A (ko) 2012-02-24
CN102482679A (zh) 2012-05-30
JP2012527249A (ja) 2012-11-08
MX2011012234A (es) 2012-03-07
WO2010135742A1 (en) 2010-11-25
AU2010249325B2 (en) 2014-12-18
PT2432884T (pt) 2016-10-06
HUE031597T2 (en) 2017-07-28
BRPI1011048A2 (pt) 2016-08-02
US9217153B2 (en) 2015-12-22
KR101719833B1 (ko) 2017-03-24

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