SI2349211T1 - Farmacevtski pripravki, ki vsebujejo ezetimib - Google Patents
Farmacevtski pripravki, ki vsebujejo ezetimibInfo
- Publication number
- SI2349211T1 SI2349211T1 SI200932050T SI200932050T SI2349211T1 SI 2349211 T1 SI2349211 T1 SI 2349211T1 SI 200932050 T SI200932050 T SI 200932050T SI 200932050 T SI200932050 T SI 200932050T SI 2349211 T1 SI2349211 T1 SI 2349211T1
- Authority
- SI
- Slovenia
- Prior art keywords
- ezetimibe
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08165462A EP2168573A1 (en) | 2008-09-30 | 2008-09-30 | Formulations comprising ezetimibe |
| EP09783518.5A EP2349211B1 (en) | 2008-09-30 | 2009-09-29 | Formulations comprising ezetimibe |
| PCT/EP2009/062575 WO2010037728A2 (en) | 2008-09-30 | 2009-09-29 | Novel ezetimibe formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2349211T1 true SI2349211T1 (sl) | 2020-11-30 |
Family
ID=40351955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200932050T SI2349211T1 (sl) | 2008-09-30 | 2009-09-29 | Farmacevtski pripravki, ki vsebujejo ezetimib |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110262497A1 (sl) |
| EP (2) | EP2168573A1 (sl) |
| JP (1) | JP2012504155A (sl) |
| CN (1) | CN102227212B (sl) |
| AU (1) | AU2009299855B2 (sl) |
| CA (1) | CA2738449C (sl) |
| SI (1) | SI2349211T1 (sl) |
| WO (1) | WO2010037728A2 (sl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2216016A1 (en) * | 2009-02-06 | 2010-08-11 | LEK Pharmaceuticals d.d. | Process for the preparation of a pharmaceutical composition comprising ezetimibe |
| WO2013066279A1 (en) * | 2011-10-13 | 2013-05-10 | Mahmut Bilgic | Solid dosage forms comprising ezetimibe |
| US10376470B2 (en) | 2012-05-01 | 2019-08-13 | Althera Life Sciences, Llc | Oral tablet formulation consisting of fixed combination of rosuvastatin and ezetimibe for treatment of hyperlipidemia and cardiovascular diseases |
| EP2844233B1 (en) * | 2012-05-01 | 2020-05-06 | Althera Life Sciences, LLC | Oral tablet formulation consisting of fixed combination of rosuvastatin and ezetimibe for treatment of hyperlipidemia and cardiovascular diseases |
| WO2013166114A1 (en) * | 2012-05-01 | 2013-11-07 | Althera Life Sciences, Llc | Oral tablet formulation consisting of fixed combination of atorvastatin and ezetimibe |
| US11058642B2 (en) | 2013-04-22 | 2021-07-13 | Tower Laboratories Ltd | Tablets with improved friability |
| CN103263394B (zh) * | 2013-05-27 | 2016-01-06 | 深圳国源国药有限公司 | 一种盐酸西替利嗪片及其有关物质质量控制方法 |
| CN103877051B (zh) * | 2014-04-19 | 2015-09-30 | 青岛科技大学 | 一种依折麦布片的制备方法 |
| JP6940411B2 (ja) | 2015-03-13 | 2021-09-29 | エスペリオン・セラピューティクス・インコーポレイテッドＥｓｐｅｒｉｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ｅｔｃ１００２及びエゼチミブを含む固定用量組合せ物及び製剤並びに心血管疾患を処置するか又は心血管疾患のリスクを低減させる方法 |
| MA41793A (fr) | 2015-03-16 | 2018-01-23 | Esperion Therapeutics Inc | Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire |
| JP6816972B2 (ja) * | 2016-05-13 | 2021-01-20 | エルメッド株式会社 | エゼチミブ含有医薬組成物及びその製造方法、エゼチミブ含有医薬組成物の硬度低下抑制剤及び硬度低下抑制方法、並びにエゼチミブ含有医薬組成物の吸湿抑制剤及び吸湿抑制方法 |
| JP2017210455A (ja) * | 2016-05-27 | 2017-11-30 | ニプロ株式会社 | エゼチミブ含有医薬組成物 |
| CZ2016539A3 (cs) | 2016-09-05 | 2018-03-14 | Zentiva, K.S. | Farmaceutická kompozice obsahující dvě rozdílné účinné látky a způsob její přípravy |
| CN106420646A (zh) * | 2016-11-29 | 2017-02-22 | 无锡福祈制药有限公司 | 一种依折麦布片的制备方法 |
| EP3437636A1 (en) * | 2017-08-02 | 2019-02-06 | Adamed sp. z o.o. | Pharmaceutical composition comprising ezetimibe |
| CN108938588B (zh) * | 2018-08-16 | 2021-06-22 | 广州维奥康药业科技有限公司 | 一种依折麦布片 |
| WO2024042061A1 (en) | 2022-08-22 | 2024-02-29 | Newamsterdam Pharma B.V. | Obicetrapib and ezetimibe combination treatment and fixed dose pharmaceutical compositions |
| WO2024041746A1 (en) | 2022-08-22 | 2024-02-29 | Newamsterdam Pharma B.V. | Fixed dose combination composition of obicetrapib and ezetimibe |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2642486B2 (ja) * | 1989-08-04 | 1997-08-20 | 田辺製薬株式会社 | 難溶性薬物の超微粒子化法 |
| IS1796B (is) * | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
| CN100509058C (zh) * | 2001-01-26 | 2009-07-08 | 先灵公司 | 过氧化物酶体增殖物激活受体(ppar)活化剂和甾醇吸收抑制剂的组合药以及对于血管适应症的治疗 |
| AR040588A1 (es) * | 2002-07-26 | 2005-04-13 | Schering Corp | Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa |
| SI1587514T1 (sl) * | 2003-01-31 | 2006-10-31 | Orexo Ab | Hitro ucinkujoc farmacevtski sestavek |
| JP4521654B2 (ja) * | 2003-04-24 | 2010-08-11 | 株式会社ダルトン | 造粒物および造粒方法 |
| WO2005004836A2 (en) * | 2003-07-11 | 2005-01-20 | F.Hoffmann-La Roche Ag | Saquinavir mesylate oral dosage form |
| JP4754211B2 (ja) * | 2004-12-28 | 2011-08-24 | ライオン株式会社 | 粒状医薬組成物及びその製造方法 |
| WO2006134604A1 (en) * | 2005-06-15 | 2006-12-21 | Hetero Drugs Limited | Combination composition of cholesterol absorption inhibitor and 3-hydroxy-3-methylglutaryl-coenzyme a (hmg-coa) reductase inhibitor |
| WO2007054975A1 (en) * | 2005-11-08 | 2007-05-18 | Panacea Biotec Ltd | Pharmaceutical compositions for the treatment of cardiovascular and other associated disorders |
| MX2008011418A (es) * | 2006-03-06 | 2008-09-22 | Teva Pharma | Composiciones de ezetimibe. |
| JP2007314529A (ja) * | 2006-04-28 | 2007-12-06 | Lion Corp | 造粒粒子、錠剤、及び造粒粒子の製造方法 |
| US20070275052A1 (en) * | 2006-05-24 | 2007-11-29 | Glenmark Pharmaceuticals Limited | Pharmaceutical compositions containing sterol inhibitors |
| US7998505B2 (en) * | 2006-10-27 | 2011-08-16 | Fmc Corporation | Dry granulation binders, products, and use thereof |
-
2008
- 2008-09-30 EP EP08165462A patent/EP2168573A1/en not_active Ceased
-
2009
- 2009-09-29 WO PCT/EP2009/062575 patent/WO2010037728A2/en active Application Filing
- 2009-09-29 EP EP09783518.5A patent/EP2349211B1/en active Active
- 2009-09-29 JP JP2011529529A patent/JP2012504155A/ja active Pending
- 2009-09-29 SI SI200932050T patent/SI2349211T1/sl unknown
- 2009-09-29 AU AU2009299855A patent/AU2009299855B2/en not_active Ceased
- 2009-09-29 US US13/121,612 patent/US20110262497A1/en not_active Abandoned
- 2009-09-29 CA CA2738449A patent/CA2738449C/en not_active Expired - Fee Related
- 2009-09-29 CN CN200980147518.5A patent/CN102227212B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009299855B2 (en) | 2016-05-19 |
| CA2738449C (en) | 2020-07-14 |
| EP2349211A2 (en) | 2011-08-03 |
| CN102227212B (zh) | 2015-10-21 |
| AU2009299855A1 (en) | 2010-04-08 |
| JP2012504155A (ja) | 2012-02-16 |
| EP2168573A1 (en) | 2010-03-31 |
| WO2010037728A3 (en) | 2010-06-10 |
| CA2738449A1 (en) | 2010-04-08 |
| EP2349211B1 (en) | 2019-12-18 |
| US20110262497A1 (en) | 2011-10-27 |
| WO2010037728A2 (en) | 2010-04-08 |
| CN102227212A (zh) | 2011-10-26 |
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