SI2115029T1 - Poli-(laktid/glikolid) z zmanjšanim takojšnjim učinkom sproščanja in metode za izdelavo polimerov - Google Patents

Poli-(laktid/glikolid) z zmanjšanim takojšnjim učinkom sproščanja in metode za izdelavo polimerov

Info

Publication number
SI2115029T1
SI2115029T1 SI200831512T SI200831512T SI2115029T1 SI 2115029 T1 SI2115029 T1 SI 2115029T1 SI 200831512 T SI200831512 T SI 200831512T SI 200831512 T SI200831512 T SI 200831512T SI 2115029 T1 SI2115029 T1 SI 2115029T1
Authority
SI
Slovenia
Prior art keywords
glycolide
lactide
poly
methods
produce polymers
Prior art date
Application number
SI200831512T
Other languages
English (en)
Inventor
Eric Dadey
John Middleton
Richard L. Norton
Original Assignee
Tolmar Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tolmar Therapeutics, Inc. filed Critical Tolmar Therapeutics, Inc.
Publication of SI2115029T1 publication Critical patent/SI2115029T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08Lactones or lactides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88Post-polymerisation treatment
    • C08G63/90Purification; Drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
SI200831512T 2007-02-15 2008-02-13 Poli-(laktid/glikolid) z zmanjšanim takojšnjim učinkom sproščanja in metode za izdelavo polimerov SI2115029T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90143507P 2007-02-15 2007-02-15
EP08725511.3A EP2115029B1 (en) 2007-02-15 2008-02-13 Low burst poly-(lactide/glycolide) and methods to produce polymers
PCT/US2008/001887 WO2008100532A1 (en) 2007-02-15 2008-02-13 Low burst poly-(lactide/glycolide) and methods to produce polymers

Publications (1)

Publication Number Publication Date
SI2115029T1 true SI2115029T1 (sl) 2016-01-29

Family

ID=39504385

Family Applications (3)

Application Number Title Priority Date Filing Date
SI200832213T SI3660073T1 (sl) 2007-02-15 2008-02-13 Poli (laktid-co-glikolid) z nizkim izpadom
SI200831512T SI2115029T1 (sl) 2007-02-15 2008-02-13 Poli-(laktid/glikolid) z zmanjšanim takojšnjim učinkom sproščanja in metode za izdelavo polimerov
SI200832098T SI3202814T1 (sl) 2007-02-15 2008-02-13 Poli-(laktid/glikolid) z nizkim razpokom in postopki za proizvodnjo polimerov

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200832213T SI3660073T1 (sl) 2007-02-15 2008-02-13 Poli (laktid-co-glikolid) z nizkim izpadom

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200832098T SI3202814T1 (sl) 2007-02-15 2008-02-13 Poli-(laktid/glikolid) z nizkim razpokom in postopki za proizvodnjo polimerov

Country Status (16)

Country Link
US (7) US9187593B2 (sl)
EP (3) EP2115029B1 (sl)
JP (3) JP5342459B2 (sl)
CA (1) CA2678350C (sl)
CY (2) CY1116785T1 (sl)
DK (3) DK2115029T3 (sl)
ES (3) ES2956244T3 (sl)
FI (1) FI3660073T3 (sl)
HK (1) HK1138303A1 (sl)
HR (3) HRP20231117T3 (sl)
HU (3) HUE047775T2 (sl)
LT (2) LT3202814T (sl)
PL (3) PL2115029T3 (sl)
PT (3) PT3202814T (sl)
SI (3) SI3660073T1 (sl)
WO (1) WO2008100532A1 (sl)

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KR20220151622A (ko) 2020-02-06 2022-11-15 오큘라 테라퓨틱스, 인코포레이티드 안질환 치료를 위한 조성물 및 방법
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Also Published As

Publication number Publication date
FI3660073T3 (fi) 2023-09-11
CY1116785T1 (el) 2017-03-15
US9187593B2 (en) 2015-11-17
PL2115029T3 (pl) 2016-01-29
ES2956244T3 (es) 2023-12-15
US20190209643A1 (en) 2019-07-11
HK1138303A1 (en) 2010-08-20
PT3660073T (pt) 2023-08-31
HUE047775T2 (hu) 2020-05-28
PT3202814T (pt) 2019-11-26
CA2678350A1 (en) 2008-08-21
US9561282B2 (en) 2017-02-07
US20170216395A1 (en) 2017-08-03
US20220202941A1 (en) 2022-06-30
LT3202814T (lt) 2019-12-10
WO2008100532A1 (en) 2008-08-21
HRP20192055T1 (hr) 2020-02-21
CY1122304T1 (el) 2021-01-27
HUE063170T2 (hu) 2024-01-28
DK2115029T3 (en) 2015-10-05
ES2550014T3 (es) 2015-11-03
HRP20150997T1 (hr) 2015-12-18
JP2010519218A (ja) 2010-06-03
US11717572B2 (en) 2023-08-08
DK3660073T3 (da) 2023-09-18
US11147880B2 (en) 2021-10-19
EP3202814A1 (en) 2017-08-09
PL3202814T3 (pl) 2020-01-31
SI3202814T1 (sl) 2019-12-31
EP2115029A1 (en) 2009-11-11
EP3660073B1 (en) 2023-07-12
LT3660073T (lt) 2023-10-10
US9974824B2 (en) 2018-05-22
DK3202814T3 (da) 2019-11-25
JP5342459B2 (ja) 2013-11-13
ES2755374T3 (es) 2020-04-22
PL3660073T3 (pl) 2023-12-27
EP2115029B1 (en) 2015-09-16
SI3660073T1 (sl) 2023-10-30
JP6195587B2 (ja) 2017-09-13
HRP20231117T3 (hr) 2023-12-22
JP2013224339A (ja) 2013-10-31
US10206970B2 (en) 2019-02-19
EP3202814B1 (en) 2019-10-16
HUE025842T2 (en) 2016-04-28
US20170095560A1 (en) 2017-04-06
JP5848290B2 (ja) 2016-01-27
JP2015127351A (ja) 2015-07-09
CA2678350C (en) 2015-11-17
US20180311305A1 (en) 2018-11-01
US20160106847A1 (en) 2016-04-21
PT2115029E (pt) 2015-10-26
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US20100292195A1 (en) 2010-11-18
EP3660073A1 (en) 2020-06-03

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