SI2086332T1 - From the bone marrow, mesenchymal stem cells are obtained as a source of neural precursors - Google Patents

From the bone marrow, mesenchymal stem cells are obtained as a source of neural precursors Download PDF

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Publication number
SI2086332T1
SI2086332T1 SI200732020T SI200732020T SI2086332T1 SI 2086332 T1 SI2086332 T1 SI 2086332T1 SI 200732020 T SI200732020 T SI 200732020T SI 200732020 T SI200732020 T SI 200732020T SI 2086332 T1 SI2086332 T1 SI 2086332T1
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Prior art keywords
stem cells
mesenchymal stem
neural
bone marrow
neural precursors
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SI200732020T
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English (en)
Slovenian (sl)
Inventor
Saud A. Sadiq
Violane K. HARRIS
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Multiple Sclerosis Research Center Of New York
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Publication of SI2086332T1 publication Critical patent/SI2086332T1/en

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
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    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2502/00—Coculture with; Conditioned medium produced by
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1353—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from bone marrow mesenchymal stem cells (BM-MSC)

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  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SI200732020T 2006-11-03 2007-11-02 From the bone marrow, mesenchymal stem cells are obtained as a source of neural precursors SI2086332T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85651506P 2006-11-03 2006-11-03
EP07867349.8A EP2086332B1 (fr) 2006-11-03 2007-11-02 Cellules souches mésenchymateuses dérivées de moelle osseuse en tant que source de progéniteurs neuraux
PCT/US2007/023184 WO2008057443A2 (fr) 2006-11-03 2007-11-02 Cellules souches mésenchymateuses dérivées de moelle osseuse en tant que source de progéniteurs neuraux

Publications (1)

Publication Number Publication Date
SI2086332T1 true SI2086332T1 (en) 2018-06-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SI200732020T SI2086332T1 (en) 2006-11-03 2007-11-02 From the bone marrow, mesenchymal stem cells are obtained as a source of neural precursors

Country Status (15)

Country Link
US (5) US8642331B2 (fr)
EP (2) EP3031326A3 (fr)
CA (1) CA2668200C (fr)
CY (1) CY1120115T1 (fr)
DK (1) DK2086332T3 (fr)
ES (1) ES2663875T3 (fr)
HR (1) HRP20180533T1 (fr)
HU (1) HUE036745T2 (fr)
LT (1) LT2086332T (fr)
MX (1) MX2009004776A (fr)
PL (1) PL2086332T3 (fr)
PT (1) PT2086332T (fr)
RS (1) RS57083B1 (fr)
SI (1) SI2086332T1 (fr)
WO (1) WO2008057443A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009004776A (es) 2006-11-03 2009-07-14 Multiple Sclerosis Res Ct Of N Celulas madre mesenquimaticas derivadas de medula osea como una fuente de progenitores neurales.
US9301975B2 (en) 2009-05-01 2016-04-05 Biocardia, Inc. Method of preparing autologous cells and method of use for therapy
US20120020931A1 (en) 2010-06-02 2012-01-26 Rutgers, The State University Of New Jersey Therapeutic encapsulated embryonic stem cells and mesenchymal stromal cells
EP3530274A1 (fr) 2010-08-18 2019-08-28 Theresa Deisher Dexamethasone pour reduire l'accumulation de cellues souches dans la rate
US20120087933A1 (en) 2010-10-08 2012-04-12 Samson Tom Enhanced msc preparations
WO2012070964A1 (fr) * 2010-11-22 2012-05-31 Farber Boris Slavinovich Oligopeptides modifiés à propriétés anticancereuses et procédé de fabrication
US10336985B2 (en) 2013-10-14 2019-07-02 Hadasit Medical Research Services & Development Limited Method of obtaining terminally differentiated neuronal lineages and uses thereof
US20170065691A1 (en) * 2014-03-20 2017-03-09 University Of Southern California Brain cancer immunotherapy
WO2016168993A1 (fr) 2015-04-22 2016-10-27 Innolife Co., Ltd. Procédés de réparation et de régénération de tissu
WO2016205371A1 (fr) * 2015-06-15 2016-12-22 Mayo Foundation For Medical Education And Research Utilisation de cellules souches mésenchymateuses autologues pour traiter l'atrophie multisystémique
WO2017062971A1 (fr) 2015-10-08 2017-04-13 Neurona Therapeutics Inc. Populations de cellules précurseurs neurales et leurs utilisations
AU2017414803A1 (en) 2017-05-15 2019-12-05 Mapi Pharma Ltd. Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells
CA3062123A1 (fr) 2017-05-15 2018-11-22 Stem Cell Medicine Ltd. Traitement de la sclerose en plaques avec des cellules souches derivees du tissu adipeux
WO2021020666A1 (fr) * 2019-07-26 2021-02-04 Brexogen Inc. Cellules précurseurs de cellules souches mésenchymateuses dérivées de cellules souches pluripotentes induites et leur procédé de préparation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037719B1 (en) * 1999-02-12 2006-05-02 Stemcells California, Inc. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
US8017112B2 (en) * 1999-05-14 2011-09-13 Henry Ford Health System Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases
US20040208858A1 (en) * 2000-04-12 2004-10-21 Gihan Tennekoon Therapeutic uses for mesenchymal stromal cells
US20040259254A1 (en) * 2001-10-30 2004-12-23 Osamu Honmou Method for inducing differentiation mesodermal stem cells, es cells or immortalized cells into nervous system cells
DK1893747T3 (en) * 2005-06-16 2014-12-01 Univ Ramot ISOLATED CELLS AND POPULATIONS INCLUDING SUCH CELLS FOR TREATING CNS DISEASES
MX2009004776A (es) 2006-11-03 2009-07-14 Multiple Sclerosis Res Ct Of N Celulas madre mesenquimaticas derivadas de medula osea como una fuente de progenitores neurales.

Also Published As

Publication number Publication date
US20150064145A1 (en) 2015-03-05
US9657268B2 (en) 2017-05-23
PT2086332T (pt) 2018-04-04
US20140308745A1 (en) 2014-10-16
PL2086332T3 (pl) 2018-07-31
WO2008057443A3 (fr) 2008-11-20
LT2086332T (lt) 2018-04-25
EP3031326A3 (fr) 2016-09-14
US8642331B2 (en) 2014-02-04
US9328329B2 (en) 2016-05-03
WO2008057443A9 (fr) 2008-07-17
EP3031326A2 (fr) 2016-06-15
HRP20180533T1 (hr) 2018-05-18
CA2668200A1 (fr) 2008-05-15
DK2086332T3 (en) 2018-04-16
CY1120115T1 (el) 2018-12-12
HUE036745T2 (hu) 2018-07-30
US20150118198A1 (en) 2015-04-30
US20100166712A1 (en) 2010-07-01
EP2086332A4 (fr) 2010-08-11
RS57083B1 (sr) 2018-06-29
CA2668200C (fr) 2017-04-18
US20110236357A1 (en) 2011-09-29
MX2009004776A (es) 2009-07-14
EP2086332B1 (fr) 2018-01-10
WO2008057443A2 (fr) 2008-05-15
ES2663875T3 (es) 2018-04-17
EP2086332A2 (fr) 2009-08-12

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