SI1669359T1 - Postopek za pripravo olanzapina in intermediat zanj - Google Patents

Postopek za pripravo olanzapina in intermediat zanj

Info

Publication number
SI1669359T1
SI1669359T1 SI200330985T SI200330985T SI1669359T1 SI 1669359 T1 SI1669359 T1 SI 1669359T1 SI 200330985 T SI200330985 T SI 200330985T SI 200330985 T SI200330985 T SI 200330985T SI 1669359 T1 SI1669359 T1 SI 1669359T1
Authority
SI
Slovenia
Prior art keywords
preparation
olanzapine
intermediate therefor
therefor
benzodiazepine
Prior art date
Application number
SI200330985T
Other languages
English (en)
Inventor
Zbigniew Majka
Tomasz Stawinski
Justyna Rechnio
Maciej Wieczorek
Original Assignee
Adamed Sp Zoo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29997625&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1669359(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adamed Sp Zoo filed Critical Adamed Sp Zoo
Publication of SI1669359T1 publication Critical patent/SI1669359T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200330985T 2002-06-20 2003-06-10 Postopek za pripravo olanzapina in intermediat zanj SI1669359T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL354642A PL199016B1 (pl) 2002-06-20 2002-06-20 Sposób wytwarzania olanzapiny
EP06100356A EP1669359B1 (en) 2002-06-20 2003-06-10 A process for the preparation of olanzapine and an intermediate therefor

Publications (1)

Publication Number Publication Date
SI1669359T1 true SI1669359T1 (sl) 2007-12-31

Family

ID=29997625

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200330985T SI1669359T1 (sl) 2002-06-20 2003-06-10 Postopek za pripravo olanzapina in intermediat zanj
SI200330991T SI1513845T2 (sl) 2002-06-20 2003-06-10 Postopek za pripravo olanzapina in intermediat zanj

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200330991T SI1513845T2 (sl) 2002-06-20 2003-06-10 Postopek za pripravo olanzapina in intermediat zanj

Country Status (17)

Country Link
EP (2) EP1513845B2 (sl)
CN (1) CN100338069C (sl)
AT (2) ATE373664T1 (sl)
AU (1) AU2003240167A1 (sl)
BR (1) BR0305100A (sl)
DE (2) DE60316047T2 (sl)
ES (2) ES2291644T5 (sl)
HR (1) HRP20041075B1 (sl)
MX (1) MXPA04012200A (sl)
NO (1) NO328873B1 (sl)
PL (1) PL199016B1 (sl)
PT (2) PT1513845E (sl)
RU (1) RU2005101324A (sl)
SI (2) SI1669359T1 (sl)
TN (1) TNSN04226A1 (sl)
UA (1) UA76616C2 (sl)
WO (1) WO2004000847A1 (sl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1575962A1 (en) 2002-12-24 2005-09-21 Teva Pharmaceutical Industries Limited Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
EP1711503A1 (en) * 2004-01-27 2006-10-18 Synthon B.V. Synthesis of olanzapine and intermediates thereof
AR047459A1 (es) 2004-01-27 2006-01-18 Synthon Bv Sales estables de 2-metil-4-(4-metil-1-piperazinil)-10h-tieno[2,3-b][1,5]benzodiazepina (olanzapina)
AR048272A1 (es) * 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
US8044196B2 (en) 2004-07-14 2011-10-25 Jubilant Organosys Limited Process for producing pure form of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
PL198589B1 (pl) 2004-11-22 2008-06-30 Adamed Sp Z Oo Sposób wytwarzania N-demetyloolanzapiny
CN100383144C (zh) * 2006-09-11 2008-04-23 杭州盛美医药科技开发有限公司 一种奥氮平的中间体及其制备与应用
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine
CN102234285B (zh) * 2010-04-19 2013-06-12 江苏豪森药业股份有限公司 奥氮平的制备方法
CN102924470B (zh) * 2011-08-31 2014-12-03 江苏豪森药业股份有限公司 新颖的奥氮平的制备方法
CN102942573B (zh) * 2011-10-09 2015-03-25 连云港恒运医药科技有限公司 奥氮平的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7306069A (sl) † 1973-05-02 1974-11-05
US4115568A (en) † 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
SU629879A3 (ru) * 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Способ получени тиено(1,5) бензодиазепинов или их солей
US5239071A (en) † 1989-11-21 1993-08-24 The B. F. Goodrich Company Process for methylating a hindered nitrogen atom in an inert non-aqueous solvent
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
DK55192D0 (da) † 1992-04-28 1992-04-28 Lundbeck & Co As H 1-piperazino-1,2-dihydroindenderivater
US6348455B1 (en) 1998-11-23 2002-02-19 Sepracor Inc. Desmetylolanzapine compositions and methods

Also Published As

Publication number Publication date
EP1513845B2 (en) 2010-11-03
ATE371660T1 (de) 2007-09-15
CN100338069C (zh) 2007-09-19
CN1662543A (zh) 2005-08-31
DE60316439D1 (de) 2007-10-31
MXPA04012200A (es) 2005-08-26
NO20040658L (no) 2004-02-13
SI1513845T1 (sl) 2007-12-31
PT1513845E (pt) 2007-11-21
PT1669359E (pt) 2007-10-16
DE60316047D1 (de) 2007-10-11
BR0305100A (pt) 2004-09-28
EP1513845B1 (en) 2007-09-19
ES2289730T3 (es) 2008-02-01
PL354642A1 (en) 2003-12-29
UA76616C2 (en) 2006-08-15
AU2003240167A1 (en) 2004-01-06
WO2004000847A1 (en) 2003-12-31
HRP20041075B1 (en) 2008-05-31
DE60316047T2 (de) 2008-05-21
DE60316439T3 (de) 2011-05-05
ATE373664T1 (de) 2007-10-15
ES2291644T3 (es) 2008-03-01
ES2291644T5 (es) 2011-02-15
EP1669359B1 (en) 2007-08-29
EP1669359A1 (en) 2006-06-14
NO328873B1 (no) 2010-06-07
SI1513845T2 (sl) 2011-01-31
EP1513845A1 (en) 2005-03-16
DE60316439T2 (de) 2008-07-31
TNSN04226A1 (en) 2007-03-12
HRP20041075A2 (en) 2005-02-28
RU2005101324A (ru) 2005-08-10
PL199016B1 (pl) 2008-08-29

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