SI1664050T1 - Nevroprotektične biciklične spojine in farmacevtski sestavki, vsebujoči le-te - Google Patents
Nevroprotektične biciklične spojine in farmacevtski sestavki, vsebujoči le-teInfo
- Publication number
- SI1664050T1 SI1664050T1 SI200432303T SI200432303T SI1664050T1 SI 1664050 T1 SI1664050 T1 SI 1664050T1 SI 200432303 T SI200432303 T SI 200432303T SI 200432303 T SI200432303 T SI 200432303T SI 1664050 T1 SI1664050 T1 SI 1664050T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- bicyclic compounds
- neuroprotective
- neuroprotective bicyclic
- Prior art date
Links
- 125000002619 bicyclic group Chemical group 0.000 title 1
- 230000000324 neuroprotective effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49995603P | 2003-09-03 | 2003-09-03 | |
| EP04782733.2A EP1664050B1 (en) | 2003-09-03 | 2004-08-31 | Neuroprotective bicyclic compounds and pharmaceutical compositions containing them |
| PCT/US2004/028308 WO2005023815A2 (en) | 2003-09-03 | 2004-08-31 | Neuroprotective bicyclic compounds and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1664050T1 true SI1664050T1 (sl) | 2016-04-29 |
Family
ID=34272894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200432303T SI1664050T1 (sl) | 2003-09-03 | 2004-08-31 | Nevroprotektične biciklične spojine in farmacevtski sestavki, vsebujoči le-te |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8067425B2 (OSRAM) |
| EP (1) | EP1664050B1 (OSRAM) |
| JP (1) | JP4842817B2 (OSRAM) |
| DK (1) | DK1664050T3 (OSRAM) |
| ES (1) | ES2564803T3 (OSRAM) |
| HU (1) | HUE028528T2 (OSRAM) |
| PL (1) | PL1664050T3 (OSRAM) |
| SI (1) | SI1664050T1 (OSRAM) |
| WO (1) | WO2005023815A2 (OSRAM) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101632669B (zh) * | 2000-08-04 | 2011-05-18 | Dmi生物科学公司 | 二酮基哌嗪和包含它们的组合物的使用方法 |
| US7485630B2 (en) * | 2003-03-20 | 2009-02-03 | Neuren Pharmaceuticals Limited | Neuroprotective macrocyclic compounds and methods for their use |
| KR20150080004A (ko) | 2003-05-15 | 2015-07-08 | 앰피오 파마슈티컬스 인코퍼레이티드 | Ｔ-세포 매개성 질환의 치료 방법 |
| WO2008063311A2 (en) * | 2006-10-11 | 2008-05-29 | Neuren Pharmaceuticals Limited | Cyclic glycyl-2-allyl proline improves cognitive performance in impaired animals |
| US8791117B2 (en) | 2003-09-03 | 2014-07-29 | Neuren Pharmaceuticals Limited | Cyclic glycyl-2-allyl proline improves cognitive performance in impaired animals |
| WO2009146320A1 (en) | 2008-05-27 | 2009-12-03 | Dmi Life Sciences, Inc. | Therapeutic methods and compounds |
| US9891219B2 (en) * | 2008-10-10 | 2018-02-13 | Mayo Foundation For Medical Education And Research | Methods for treating neuromyelitis optica (NMO) by administration of eculizumab to an individual that is aquaporin-4 (AQP4)-IgG autoantibody positive |
| US7928233B2 (en) * | 2009-02-10 | 2011-04-19 | Hoffmann-La Roche Inc. | Spiroindolinone pyridine derivatives |
| WO2011037644A1 (en) * | 2009-09-25 | 2011-03-31 | Neuren Pharmaceuticals Limited | Cyclic glycyl-2-allyl proline and its use in treatment of peripheral neuropathy |
| JP2013537195A (ja) | 2010-09-07 | 2013-09-30 | ディエムアイ アクイジション コーポレイション | 疾患の治療 |
| BR112014007657A2 (pt) | 2011-10-10 | 2017-04-11 | Ampio Pharmaceuticals Inc | dispositivos médicos implantáveis com tolerância imune aperfeiçoada e métodos para produção e implantação |
| AU2012323305B2 (en) | 2011-10-10 | 2017-07-27 | Ampio Pharmaceuticals, Inc. | Treatment of degenerative joint disease |
| MX355446B (es) | 2011-10-28 | 2018-04-18 | Ampio Pharmaceuticals Inc | Tratamiento de rinitis. |
| JP6465803B2 (ja) * | 2012-10-22 | 2019-02-06 | シティ・オブ・ホープＣｉｔｙ ｏｆ Ｈｏｐｅ | Ｅｔｐ誘導体 |
| BR112015020469A2 (pt) | 2013-03-15 | 2020-01-28 | Ampio Pharmaceuticals Inc | Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo |
| JP6574769B2 (ja) | 2013-07-25 | 2019-09-11 | ニューレン ファーマシューティカルズ リミテッド | 二環式化合物ならびに自閉症スペクトラム障害および神経発達障害の治療におけるそれらの使用方法 |
| CA2958080A1 (en) | 2014-08-18 | 2016-02-25 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| HK1246669A1 (zh) | 2015-06-22 | 2018-09-14 | Ampio Pharmaceuticals, Inc. | 人血清白蛋白低分子量组分在疾病治疗中的应用 |
| JP7381000B2 (ja) * | 2016-05-26 | 2023-11-15 | 株式会社アミノアップ | 睡眠改善剤 |
| EP3512520B1 (en) | 2016-09-15 | 2023-06-21 | City of Hope | Dithio derivatives of epidithiodiketopiperazine (etp) |
| CN119112885A (zh) | 2018-03-16 | 2024-12-13 | 脑科学香料株式会社 | 缺氧障碍、缺血再灌注障碍或炎症的预防或治疗剂，移植用细胞保护剂，及生物体防腐剂 |
| AU2019271189A1 (en) | 2018-05-15 | 2021-01-07 | Lloyd Hung Loi TRAN | Therapeutic agent composition and method of use, for treatment of mild cognitive impairment, depression, and psychological disorders |
| BR112022007636A2 (pt) | 2019-10-22 | 2022-07-12 | Neuren Pharmaceuticals Ltd | Compostos bicíclicos e métodos para seus usos no tratamento da síndrome de pitt-hopkins |
| TW202245773A (zh) * | 2021-02-12 | 2022-12-01 | 紐西蘭商紐藍製藥公司 | 普威二氏症候群之治療 |
| WO2025088052A1 (en) * | 2023-10-26 | 2025-05-01 | Rousselot Bv | Cyclic analogue of glycine-proline for use in the prevention and/or treatment of medical implant-related fibrosis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH469006A (de) * | 1965-07-07 | 1969-02-28 | Sandoz Ag | Verfahren zur Herstellung neuer synthetischer Alkaloide |
| FI941826L (fi) * | 1993-04-21 | 1994-10-22 | Takeda Chemical Industries Ltd | Menetelmät ja koostumukset elimen hypofunktion ennaltaehkäisemiseksi ja/tai terapeuttiseksi hoitamiseksi |
| US7202279B1 (en) | 1998-02-11 | 2007-04-10 | Georgetown University | Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders |
| WO2003039487A2 (en) * | 2001-11-09 | 2003-05-15 | Neuronz Limited | Cyclo(prolyl-glycine) and methods of use to treat neural disorders |
| US7232798B2 (en) * | 2001-11-13 | 2007-06-19 | Tran Loi H | Neuroprotection and neuroegenisis by administering cyclic prolyl glycine |
| AU2002363800A1 (en) | 2001-11-13 | 2003-05-26 | Loi Tran | Therapeutic agent composition and method of use |
| US7485630B2 (en) * | 2003-03-20 | 2009-02-03 | Neuren Pharmaceuticals Limited | Neuroprotective macrocyclic compounds and methods for their use |
-
2004
- 2004-08-31 JP JP2006525396A patent/JP4842817B2/ja not_active Expired - Lifetime
- 2004-08-31 ES ES04782733.2T patent/ES2564803T3/es not_active Expired - Lifetime
- 2004-08-31 WO PCT/US2004/028308 patent/WO2005023815A2/en not_active Ceased
- 2004-08-31 EP EP04782733.2A patent/EP1664050B1/en not_active Expired - Lifetime
- 2004-08-31 HU HUE04782733A patent/HUE028528T2/en unknown
- 2004-08-31 US US10/570,395 patent/US8067425B2/en not_active Expired - Lifetime
- 2004-08-31 PL PL04782733T patent/PL1664050T3/pl unknown
- 2004-08-31 SI SI200432303T patent/SI1664050T1/sl unknown
- 2004-08-31 DK DK04782733.2T patent/DK1664050T3/en active
-
2006
- 2006-04-07 US US11/399,974 patent/US7776876B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP4842817B2 (ja) | 2011-12-21 |
| US7776876B2 (en) | 2010-08-17 |
| EP1664050A2 (en) | 2006-06-07 |
| WO2005023815A3 (en) | 2005-07-21 |
| WO2005023815A2 (en) | 2005-03-17 |
| US20070197511A1 (en) | 2007-08-23 |
| US8067425B2 (en) | 2011-11-29 |
| HUE028528T2 (en) | 2016-12-28 |
| JP2007504235A (ja) | 2007-03-01 |
| US20060258663A1 (en) | 2006-11-16 |
| DK1664050T3 (en) | 2016-03-07 |
| ES2564803T3 (es) | 2016-03-29 |
| EP1664050B1 (en) | 2015-12-09 |
| PL1664050T3 (pl) | 2016-08-31 |
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