SI1628956T1 - Postopek za pripravo spojin z ACE inhibitornim delovanjem - Google Patents

Postopek za pripravo spojin z ACE inhibitornim delovanjem

Info

Publication number
SI1628956T1
SI1628956T1 SI200431600T SI200431600T SI1628956T1 SI 1628956 T1 SI1628956 T1 SI 1628956T1 SI 200431600 T SI200431600 T SI 200431600T SI 200431600 T SI200431600 T SI 200431600T SI 1628956 T1 SI1628956 T1 SI 1628956T1
Authority
SI
Slovenia
Prior art keywords
compounds
preparation
inhibitory action
ace inhibitory
amino acid
Prior art date
Application number
SI200431600T
Other languages
English (en)
Inventor
Branko Jenko
Original Assignee
Lek Pharmaceuticals D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals D.D. filed Critical Lek Pharmaceuticals D.D.
Publication of SI1628956T1 publication Critical patent/SI1628956T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200431600T 2003-05-16 2004-05-07 Postopek za pripravo spojin z ACE inhibitornim delovanjem SI1628956T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI200300123A SI21507A (sl) 2003-05-16 2003-05-16 Postopek za pripravo spojin z ace inhibitornim delovanjem
PCT/SI2004/000021 WO2004101515A1 (en) 2003-05-16 2004-05-07 A process for the preparation of compounds having an ace inhibitory action
EP04731808A EP1628956B1 (en) 2003-05-16 2004-05-07 A process for the preparation of compounds having an ace inhibitory action

Publications (1)

Publication Number Publication Date
SI1628956T1 true SI1628956T1 (sl) 2011-03-31

Family

ID=33448812

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200300123A SI21507A (sl) 2003-05-16 2003-05-16 Postopek za pripravo spojin z ace inhibitornim delovanjem
SI200431600T SI1628956T1 (sl) 2003-05-16 2004-05-07 Postopek za pripravo spojin z ACE inhibitornim delovanjem

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200300123A SI21507A (sl) 2003-05-16 2003-05-16 Postopek za pripravo spojin z ace inhibitornim delovanjem

Country Status (7)

Country Link
US (1) US7671215B2 (sl)
EP (1) EP1628956B1 (sl)
AT (1) ATE488498T1 (sl)
DE (1) DE602004030112D1 (sl)
RU (1) RU2377236C2 (sl)
SI (2) SI21507A (sl)
WO (1) WO2004101515A1 (sl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080188545A1 (en) * 2006-12-21 2008-08-07 Alimardanov Asaf R Synthesis of pyrrolidine compounds
US20090076126A1 (en) * 2007-09-17 2009-03-19 Protia, Llc Deuterium-enriched enalapril
RU2012103753A (ru) 2009-07-16 2013-08-27 Эбботт Лабораториз Способ синтеза (2s, 3ar, 7as)-октагидро-1н-индол-карбоновой кислоты в качестве промежуточного соединения для получения трандолаприла
ES2670854T3 (es) * 2012-10-10 2018-06-01 Piramal Enterprises Limited Un proceso mejorado para la preparación de perindoprilo intermedio

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL4915C (sl) 1913-08-18
FR2620709B1 (fr) * 1987-09-17 1990-09-07 Adir Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese
US5864040A (en) 1996-01-11 1999-01-26 American Home Products Corporation Benzimidazole phosphono-amino acids
GB9710612D0 (en) 1997-05-23 1997-07-16 Glaxo Group Ltd Synthesis of acridine derivatives
UA73553C2 (en) 2000-03-31 2005-08-15 Pfizer Prod Inc Piperazine derivatives
GB2375762B (en) * 2001-05-21 2003-10-01 Fermenta Biotech Ltd Stereospecific synthesis of 2-hydroxy-4-phenyl-butyric acid esters
WO2002094857A1 (en) 2001-05-23 2002-11-28 The Curators Of The University Of Missouri Inverse solid phase synthesis of peptides
AR036187A1 (es) * 2001-07-24 2004-08-18 Adir Un proceso para la preparacion de perindopril, compuestos analogos y sus sales, compuesto intermediario 2,5-dioxo-oxazolidina y proceso para preparar un intermediario
GB0119795D0 (en) 2001-08-14 2001-10-03 Smithkline Beecham Plc Novel process

Also Published As

Publication number Publication date
RU2005139158A (ru) 2007-06-27
WO2004101515A1 (en) 2004-11-25
ATE488498T1 (de) 2010-12-15
SI21507A (sl) 2004-12-31
DE602004030112D1 (de) 2010-12-30
RU2377236C2 (ru) 2009-12-27
EP1628956B1 (en) 2010-11-17
US20070072919A1 (en) 2007-03-29
US7671215B2 (en) 2010-03-02
EP1628956A1 (en) 2006-03-01

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