SI1622639T1 - Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke - Google Patents

Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke

Info

Publication number
SI1622639T1
SI1622639T1 SI200432000T SI200432000T SI1622639T1 SI 1622639 T1 SI1622639 T1 SI 1622639T1 SI 200432000 T SI200432000 T SI 200432000T SI 200432000 T SI200432000 T SI 200432000T SI 1622639 T1 SI1622639 T1 SI 1622639T1
Authority
SI
Slovenia
Prior art keywords
plasminogen
intravenous injection
treating cerebral
cerebral stroke
neurotoxic
Prior art date
Application number
SI200432000T
Other languages
Slovenian (sl)
Inventor
Mariola Sohngen
Wolfgang Sohngen
Wolf-Dieter Schleuning
Robert Medcalf
Original Assignee
Lundbeck, H., A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck, H., A/S filed Critical Lundbeck, H., A/S
Priority claimed from EP04730516A external-priority patent/EP1622639B1/en
Publication of SI1622639T1 publication Critical patent/SI1622639T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SI200432000T 2003-05-02 2004-04-30 Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke SI1622639T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EPPCT/EP03/04608 2003-05-02
PCT/EP2003/004729 WO2004096267A1 (en) 2003-05-02 2003-05-06 Intravenous injection of non-neurotoxic plasminogen activators for the treatment of stroke
EP04730516A EP1622639B1 (en) 2003-05-02 2004-04-30 Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke
PCT/EP2004/004626 WO2004096268A2 (en) 2003-05-02 2004-04-30 Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke

Publications (1)

Publication Number Publication Date
SI1622639T1 true SI1622639T1 (en) 2013-05-31

Family

ID=33395696

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200432000T SI1622639T1 (en) 2003-05-02 2004-04-30 Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke

Country Status (14)

Country Link
JP (1) JP2012077090A (en)
CN (1) CN1849133B (en)
AU (3) AU2003227721A1 (en)
CY (1) CY1114254T1 (en)
DK (1) DK1622639T3 (en)
EA (2) EA201000501A1 (en)
ES (1) ES2401782T3 (en)
HK (1) HK1092045A1 (en)
IL (1) IL171636A (en)
MY (1) MY151447A (en)
PT (1) PT1622639E (en)
SI (1) SI1622639T1 (en)
WO (1) WO2004096267A1 (en)
ZA (2) ZA200703704B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10153601A1 (en) 2001-11-02 2003-05-22 Paion Gmbh DSPA for the treatment of stroke
TWI445540B (en) 2007-04-20 2014-07-21 Ajinomoto Kk Anti-hypothermia composition
EP2014296A1 (en) * 2007-07-10 2009-01-14 PAION Deutschland GmbH Novel strategies for increasing the reperfusion in obstructed blood vessel
AR067345A1 (en) * 2007-07-10 2009-10-07 Paion Deutschland Gmbh USE OF THROMBOMODULIN FOR THE PREPARATION OF A THROMBOLITIC MEDICINAL PRODUCT

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK176140B1 (en) * 1988-07-20 2006-09-25 Schering Ag Patentabteilung Bat salivary plasminogen activators
NL8902454A (en) * 1989-10-03 1991-05-01 Stichting Centraal Lab MUTANTS OF THE HUMANE PLASMINOGENIC ACTIVATOR INHIBITOR 1 (PAI-1), THEIR PREPARATION AND USE, AND RECOMBINANT POLYNUCLEOTIDES INCLUDING GENETIC INFORMATION CODING FOR THESE MUTANTS.
RU2128705C1 (en) * 1991-09-05 1999-04-10 Шеринг Аг Protein inhibiting collagen-caused aggregation of mammalian platelets, recombinant protein inhibiting collagen-caused aggregation of platelets, dna fragment encoding recombinant protein, expression vector (variants), strain of cultured mammalian cells bhk - producer of recombinant protein (variants), method of preparing recombinant protein, pharmaceutical composition
DE10153601A1 (en) * 2001-11-02 2003-05-22 Paion Gmbh DSPA for the treatment of stroke

Also Published As

Publication number Publication date
AU2004233601A1 (en) 2004-11-11
ZA200509053B (en) 2007-11-28
AU2004233601B2 (en) 2009-11-26
AU2010200718A1 (en) 2010-03-18
ZA200703704B (en) 2008-08-27
DK1622639T3 (en) 2013-04-15
JP2012077090A (en) 2012-04-19
CN1849133B (en) 2011-03-30
IL171636A (en) 2013-07-31
PT1622639E (en) 2013-04-01
HK1092045A1 (en) 2007-02-02
CY1114254T1 (en) 2016-08-31
CN1849133A (en) 2006-10-18
WO2004096267A1 (en) 2004-11-11
EA201000501A1 (en) 2010-10-29
ES2401782T3 (en) 2013-04-24
EA200501733A1 (en) 2006-06-30
AU2003227721A1 (en) 2004-11-23
EA013837B1 (en) 2010-08-30
MY151447A (en) 2014-05-30

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