SI1377574T1 - - Google Patents
Info
- Publication number
- SI1377574T1 SI1377574T1 SI200230083T SI200230083T SI1377574T1 SI 1377574 T1 SI1377574 T1 SI 1377574T1 SI 200230083 T SI200230083 T SI 200230083T SI 200230083 T SI200230083 T SI 200230083T SI 1377574 T1 SI1377574 T1 SI 1377574T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pde3
- inhibitors
- compounds
- formula
- description
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Luminescent Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Electroluminescent Light Sources (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01104086 | 2001-02-21 | ||
| EP02722110A EP1377574B1 (en) | 2001-02-21 | 2002-02-21 | 6-phenylbenzonaphthyridines |
| PCT/EP2002/001819 WO2002066476A1 (en) | 2001-02-21 | 2002-02-21 | 6-phenylbenzonaphthyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1377574T1 true SI1377574T1 (ru) | 2005-08-31 |
Family
ID=8176545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200230083T SI1377574T1 (ru) | 2001-02-21 | 2002-02-21 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6936622B2 (ru) |
| EP (1) | EP1377574B1 (ru) |
| JP (1) | JP4248245B2 (ru) |
| AT (1) | ATE287403T1 (ru) |
| AU (1) | AU2002253045B2 (ru) |
| CA (1) | CA2438717C (ru) |
| DE (1) | DE60202669T2 (ru) |
| DK (1) | DK1377574T3 (ru) |
| ES (1) | ES2236504T3 (ru) |
| PT (1) | PT1377574E (ru) |
| SI (1) | SI1377574T1 (ru) |
| WO (1) | WO2002066476A1 (ru) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004018465A2 (en) * | 2002-08-17 | 2004-03-04 | Altana Pharma Ag | Benzonaphthyridines with pde 3/4 inhibiting activity |
| WO2004018431A2 (en) * | 2002-08-17 | 2004-03-04 | Altana Pharma Ag | Novel phenanthridines |
| JP4587295B2 (ja) | 2002-08-29 | 2010-11-24 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｐｄｅ４インヒビターとしての３−ヒドロキシ−６−フェニルフェナントリジン |
| US7470704B2 (en) * | 2002-09-04 | 2008-12-30 | Nycomed Gmbh | Benzonaphthyridines |
| WO2004022557A1 (en) * | 2002-09-04 | 2004-03-18 | Altana Pharma Ag | Novel benzonaphthyridines |
| AU2005212857B2 (en) * | 2004-02-18 | 2011-04-28 | Takeda Gmbh | Novel guanidinyl-substituted hydroxy-6-phenylphenenthridines as effective phosphodiesterase (PDE) 4 inhibitors |
| AR049419A1 (es) * | 2004-03-03 | 2006-08-02 | Altana Pharma Ag | Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo |
| EA017282B1 (ru) * | 2004-03-03 | 2012-11-30 | Никомед Гмбх | Производное гидрокси-6-гетероарилфенантридина и его применение в качестве ингибитора pde4 |
| US20070185149A1 (en) * | 2004-03-10 | 2007-08-09 | Altana Pharma Ag | Novel amido-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibtors |
| AU2005223386A1 (en) | 2004-03-17 | 2005-09-29 | Nycomed Gmbh | Novel N- (alkoxyalkyl) carbamoyl - substituted 6-phenyl-benzonaphthyridine derivatives and their use as PDE3/4 inhibitors |
| ME01172B (me) | 2005-03-02 | 2013-03-20 | Takeda Gmbh | (2r,4ar,10br)-6-(2,6-dimetoksipiridin-3-il)-9-etoksi-8-metoksi-1,2,3,4,4a,10b-heksahidrofenantridin-2-ol, hci so |
| WO2018069210A1 (en) | 2016-10-10 | 2018-04-19 | Takeda Gmbh | Tetrahydrofuro[3,4-c]isoquinolines as inhibitors of pde4 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2195189T3 (es) * | 1996-11-11 | 2003-12-01 | Altana Pharma Ag | Benzonaftiridinas como agentes terapeuticos bronquiales. |
| US6143759A (en) | 1997-03-07 | 2000-11-07 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tetrazoles |
| AU8106598A (en) | 1997-06-03 | 1998-12-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Benzonaphthyridine |
| PT1075477E (pt) | 1998-05-05 | 2003-07-31 | Altana Pharma Ag | Novos n-oxidos de benzonaftiridina |
| CA2342245A1 (en) * | 1998-08-31 | 2000-03-09 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Benzonaphthyridine-n-oxides comprising a pde3 and pde4 inhibiting activity |
-
2002
- 2002-02-21 WO PCT/EP2002/001819 patent/WO2002066476A1/en active IP Right Grant
- 2002-02-21 US US10/467,568 patent/US6936622B2/en not_active Expired - Fee Related
- 2002-02-21 DE DE60202669T patent/DE60202669T2/de not_active Expired - Lifetime
- 2002-02-21 AT AT02722110T patent/ATE287403T1/de active
- 2002-02-21 PT PT02722110T patent/PT1377574E/pt unknown
- 2002-02-21 EP EP02722110A patent/EP1377574B1/en not_active Expired - Lifetime
- 2002-02-21 SI SI200230083T patent/SI1377574T1/xx unknown
- 2002-02-21 ES ES02722110T patent/ES2236504T3/es not_active Expired - Lifetime
- 2002-02-21 JP JP2002565990A patent/JP4248245B2/ja not_active Expired - Fee Related
- 2002-02-21 AU AU2002253045A patent/AU2002253045B2/en not_active Ceased
- 2002-02-21 DK DK02722110T patent/DK1377574T3/da active
- 2002-02-21 CA CA2438717A patent/CA2438717C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20040097537A1 (en) | 2004-05-20 |
| ES2236504T3 (es) | 2005-07-16 |
| DE60202669D1 (de) | 2005-02-24 |
| PT1377574E (pt) | 2005-05-31 |
| CA2438717C (en) | 2011-08-30 |
| JP2004526712A (ja) | 2004-09-02 |
| ATE287403T1 (de) | 2005-02-15 |
| US6936622B2 (en) | 2005-08-30 |
| WO2002066476A1 (en) | 2002-08-29 |
| JP4248245B2 (ja) | 2009-04-02 |
| DE60202669T2 (de) | 2005-09-15 |
| AU2002253045B2 (en) | 2007-07-12 |
| WO2002066476A9 (en) | 2003-10-30 |
| DK1377574T3 (da) | 2005-04-25 |
| EP1377574B1 (en) | 2005-01-19 |
| CA2438717A1 (en) | 2002-08-29 |
| EP1377574A1 (en) | 2004-01-07 |
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