SI0787726T1 - Novel compound, process for producing the same, and antitumor agent - Google Patents

Novel compound, process for producing the same, and antitumor agent

Info

Publication number
SI0787726T1
SI0787726T1 SI9530567T SI9530567T SI0787726T1 SI 0787726 T1 SI0787726 T1 SI 0787726T1 SI 9530567 T SI9530567 T SI 9530567T SI 9530567 T SI9530567 T SI 9530567T SI 0787726 T1 SI0787726 T1 SI 0787726T1
Authority
SI
Slovenia
Prior art keywords
hydrogen atom
producing
same
group
lower alkyl
Prior art date
Application number
SI9530567T
Other languages
English (en)
Slovenian (sl)
Inventor
Kyoji Tomita
Katsumi Chiba
Shigeki Kashimoto
Koh-Ichiro Shibamori
Yasunori Tsuzuki
Original Assignee
Dainippon Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co., Ltd. filed Critical Dainippon Pharmaceutical Co., Ltd.
Publication of SI0787726T1 publication Critical patent/SI0787726T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9530567T 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent SI0787726T1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP15657894 1994-06-14
JP19792194 1994-07-28
JP30691494 1994-11-15
JP33995694 1994-12-28
JP8170595 1995-03-13
PCT/JP1995/001110 WO1995034559A1 (fr) 1994-06-14 1995-06-06 Nouveau compose, son procede de production et agent antitumoral
EP95920265A EP0787726B1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent

Publications (1)

Publication Number Publication Date
SI0787726T1 true SI0787726T1 (en) 2002-04-30

Family

ID=27524935

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9530567T SI0787726T1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent

Country Status (27)

Country Link
US (1) US5817669A (el)
EP (1) EP0787726B1 (el)
JP (1) JP3391796B2 (el)
KR (1) KR100350921B1 (el)
CN (1) CN1053668C (el)
AT (1) ATE209645T1 (el)
AU (1) AU679859B2 (el)
BR (1) BR9508037A (el)
CA (1) CA2192824C (el)
CZ (1) CZ292631B6 (el)
DE (1) DE69524251T2 (el)
DK (1) DK0787726T3 (el)
ES (1) ES2163512T3 (el)
FI (1) FI112485B (el)
HK (1) HK1000495A1 (el)
HU (1) HU220072B (el)
MX (1) MX9606331A (el)
NO (1) NO307255B1 (el)
NZ (1) NZ287139A (el)
PL (1) PL181867B1 (el)
PT (1) PT787726E (el)
RO (1) RO117793B1 (el)
RU (1) RU2151770C1 (el)
SI (1) SI0787726T1 (el)
SK (1) SK281341B6 (el)
TW (1) TW319769B (el)
WO (1) WO1995034559A1 (el)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005504807A (ja) 2001-09-26 2005-02-17 バイエル・フアーマシユーチカルズ・コーポレーシヨン 抗糖尿病薬としての１，８−ナフチリジン誘導体
US6802423B2 (en) * 2002-02-20 2004-10-12 Trans Global Foods, Inc. Disposable food delivery apparatus
US7163948B2 (en) * 2003-04-07 2007-01-16 Cylene Pharmaceuticals, Inc. Heterocyclic substituted 1,4-dihydri-4ox9-1,8-naphthyridine analogs
BRPI0413964B8 (pt) * 2003-09-10 2021-05-25 Kyorin Seiyaku Kk ácido derivado do ácido carboxílico quinolona, sua composição e agente antibacterial
DE10352979A1 (de) * 2003-11-13 2005-06-09 Merck Patent Gmbh Pyridopyrimidinone
CA2954578A1 (en) * 2004-03-15 2005-09-29 Sunesis Pharmaceuticals, Inc. Methods of using sns-595 in treating cancer
AU2013201203C1 (en) * 2004-03-15 2015-04-23 Sumitomo Dainippon Pharma Co., Ltd. Sns-595 and methods of using the same
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
CA2619663A1 (en) * 2005-08-19 2007-02-22 Cylene Pharmaceuticals, Inc. Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof
KR20080041298A (ko) * 2005-09-02 2008-05-09 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한(＋)-1,4-디히드로-7-[(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
AU2013219242C1 (en) * 2005-09-02 2016-09-22 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
CN104873502A (zh) * 2005-09-02 2015-09-02 逊尼希思制药公司 使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
CA2845095A1 (en) * 2005-09-02 2007-03-08 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
TW200800983A (en) 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
CN101300258A (zh) * 2005-09-14 2008-11-05 詹森药业有限公司 作为c-fms激酶抑制剂的5-氧代-5,8-二氢-吡啶并-嘧啶类
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
EP2354138A1 (en) * 2006-06-12 2011-08-10 Sunesis Pharmaceuticals, Inc. Compounds and compositions for treatment of cancer
WO2008016678A2 (en) * 2006-08-01 2008-02-07 Sunesis Pharmaceuticals, Inc. Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
US20080063642A1 (en) * 2006-08-02 2008-03-13 Adelman Daniel C Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of certain hematologic disorders
WO2009054935A1 (en) * 2007-10-22 2009-04-30 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid in combination therapy
AU2008335772B2 (en) * 2007-12-10 2014-11-27 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3- methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1- (2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
BRPI0923780A2 (pt) * 2008-12-31 2015-07-21 Sunesis Pharmaceuticals Inc Processo para preparar composto, processo para decomposição do composto, composto, composição, método para tratar câncer, e, pelo menos um quilograma de composto
WO2010099526A1 (en) 2009-02-27 2010-09-02 Sunesis Pharmaceuticals, Inc. Methods of using sns-595 for treatment of cancer subjects with reduced brca2 activity
UA110465C2 (en) * 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
US8470817B2 (en) * 2009-10-26 2013-06-25 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer
HUE030791T2 (en) * 2011-05-13 2017-06-28 Array Biopharma Inc Pyrrolidinylurea, Pyrrolidinylthiocarbamind and Pyrrolidinylguanidine Compounds as Trkaquinase Inhibitors
CN103497186B (zh) * 2013-09-24 2015-02-25 浙江司太立制药股份有限公司 含有烷氧亚氨基取代的萘啶酮羧酸衍生物及其制备方法
AU2018238079B2 (en) * 2017-03-24 2022-03-03 Wakunaga Pharmaceutical Co., Ltd. Novel pyridone carboxylic acid derivative or salt thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
EP0154780B1 (en) * 1984-01-26 1990-04-11 Abbott Laboratories Quinoline antibacterial compounds
JPS61152682A (ja) * 1984-12-27 1986-07-11 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸誘導体、そのエステルおよびその塩
JPS61251667A (ja) * 1985-04-30 1986-11-08 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物
IL79110A0 (en) * 1985-06-13 1986-09-30 Schering Corp Polycyclic quinoline,naphthyridine and pyrazinopyridine derivatives
WO1986007357A2 (en) * 1985-06-14 1986-12-18 Upjohn Co Cyclopentapyrazole and tetrahydroindazole compounds
JPS6233176A (ja) * 1985-08-05 1987-02-13 Toyama Chem Co Ltd １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
JP2704428B2 (ja) * 1988-06-15 1998-01-26 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
JPH06233176A (ja) * 1993-01-29 1994-08-19 Sony Corp ビデオカメラ

Also Published As

Publication number Publication date
DE69524251D1 (de) 2002-01-10
EP0787726A4 (el) 1997-08-06
RU2151770C1 (ru) 2000-06-27
CZ364396A3 (en) 1997-06-11
NO965305D0 (no) 1996-12-11
WO1995034559A1 (fr) 1995-12-21
HK1000495A1 (en) 2002-07-19
CN1158614A (zh) 1997-09-03
EP0787726B1 (en) 2001-11-28
SK281341B6 (sk) 2001-02-12
NZ287139A (en) 1997-07-27
JP3391796B2 (ja) 2003-03-31
DK0787726T3 (da) 2002-02-11
CZ292631B6 (cs) 2003-11-12
KR100350921B1 (ko) 2002-11-18
PT787726E (pt) 2002-04-29
US5817669A (en) 1998-10-06
FI965020A0 (fi) 1996-12-13
ATE209645T1 (de) 2001-12-15
PL317726A1 (en) 1997-04-28
HU220072B (hu) 2001-10-28
HU9603455D0 (en) 1997-02-28
ES2163512T3 (es) 2002-02-01
SK157496A3 (en) 1997-08-06
NO307255B1 (no) 2000-03-06
NO965305L (no) 1997-02-04
BR9508037A (pt) 1997-09-16
CN1053668C (zh) 2000-06-21
PL181867B1 (pl) 2001-09-28
MX9606331A (es) 1997-03-29
FI965020A (fi) 1996-12-16
EP0787726A1 (en) 1997-08-06
CA2192824A1 (en) 1995-12-21
RO117793B1 (ro) 2002-07-30
DE69524251T2 (de) 2002-07-11
AU2576795A (en) 1996-01-05
HUT75777A (en) 1997-05-28
CA2192824C (en) 2006-11-07
FI112485B (fi) 2003-12-15
TW319769B (el) 1997-11-11
AU679859B2 (en) 1997-07-10

Similar Documents

Publication Publication Date Title
AU679859B2 (en) Novel compound, process for producing the same, and antitumor agent
EP0945452A4 (en) SUGAR COMPOSITIONS, GELLING AGENTS, GELLING AGENT COMPOSITIONS, METHODS OF PREPARING SAME, AND GEL COMPOSITIONS
ES8607287A1 (es) Un procedimiento para preparar derivados de 1,8-naftiridina
HUT54685A (en) Process for producing condensed heterocyclic compounds, salts and intermediates, and fungicide compositions containing them
ZA88309B (en) 3(2h)pyridazinone,process for its preparation and antagonistic agent against srs-a containing it
HUT59378A (en) Process for producing urea derivatives and pharmaceutical compositions comprising such compounds
UA41904C2 (uk) Спосіб одержання бензопіранових сполук, проміжні сполуки, спосіб одержання проміжних сполук
HUT47099A (en) Process for producing pyridine derivatives and pharmaceutical compositions comprising such compounds
AU7928791A (en) Bisphophonic acid derivatives, their production and use
NZ222185A (en) N-substituted methanesulphonamide derivatives, and anticancer compositions containing such
AU1589695A (en) Bicyclic amino group-substituted pyridonecarboxylic acid derivatives, esters thereof and salts thereof, and bicyclic amines useful as intermediates thereof
HUT59083A (en) Improved process for producing 4-methyl-sulfonyl-benzoic acid derivatives
EP0971899A4 (en) HEXAHYDROINDENOPYRIDINE COMPOUNDS WITH ANTISPERMATOGENIC ACTIVITY
EP0827961A4 (en) METHOD FOR PRODUCING BETA-LACTAM COMPOUNDS
ZA869742B (en) Novel pregnane derivatives,processes for their preparation and pharmaceutical compositions containing same
ZA803682B (en) Clavulanic acid derivatives, a process for their preparation and their use
HU906407D0 (en) Process for producing new inozine- and guanozine derivatives and pharmaceutical compositions containing them as active components