SG84688G - Medicinal compositions comprising as an active ingredient substituted 1,4-benzo-quinones - Google Patents

Medicinal compositions comprising as an active ingredient substituted 1,4-benzo-quinones

Info

Publication number
SG84688G
SG84688G SG846/88A SG84688A SG84688G SG 84688 G SG84688 G SG 84688G SG 846/88 A SG846/88 A SG 846/88A SG 84688 A SG84688 A SG 84688A SG 84688 G SG84688 G SG 84688G
Authority
SG
Singapore
Prior art keywords
quinones
benzo
active ingredient
medicinal compositions
substituted
Prior art date
Application number
SG846/88A
Other languages
English (en)
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of SG84688G publication Critical patent/SG84688G/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • C07C46/02Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • C07C46/02Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C07C46/08Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring with molecular oxygen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00Quinones
    • C07C50/26Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/28Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
SG846/88A 1979-12-30 1988-11-30 Medicinal compositions comprising as an active ingredient substituted 1,4-benzo-quinones SG84688G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17112579A JPS5697223A (en) 1979-12-30 1979-12-30 Tissue metabolism activator

Publications (1)

Publication Number Publication Date
SG84688G true SG84688G (en) 1989-04-14

Family

ID=15917438

Family Applications (1)

Application Number Title Priority Date Filing Date
SG846/88A SG84688G (en) 1979-12-30 1988-11-30 Medicinal compositions comprising as an active ingredient substituted 1,4-benzo-quinones

Country Status (9)

Country Link
US (1) US4436753A (it)
EP (1) EP0031727B1 (it)
JP (1) JPS5697223A (it)
AT (1) ATE21031T1 (it)
DE (2) DE3049039A1 (it)
HK (1) HK64089A (it)
IT (1) IT1144075B (it)
MY (1) MY8700652A (it)
SG (1) SG84688G (it)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0021841B1 (en) * 1979-06-28 1984-10-24 Takeda Chemical Industries, Ltd. 2,3-dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives
JPS58174313A (ja) * 1982-04-06 1983-10-13 Takeda Chem Ind Ltd 動物組織の線維化抑制剤
JPS58177934A (ja) * 1982-04-13 1983-10-18 Takeda Chem Ind Ltd ベンゾキノン誘導体
US4808339A (en) * 1982-04-13 1989-02-28 Takeda Chemical Industries, Ltd. Benzoquinone derivatives
JPS59204167A (ja) * 1983-05-02 1984-11-19 Takeda Chem Ind Ltd ヒドロキノン誘導体およびその製法
JPS60130515A (ja) * 1983-12-15 1985-07-12 Shiratori Seiyaku Kk 血中2,3−ジホスホグリセリン酸上昇剤
JPS60255749A (ja) * 1984-05-31 1985-12-17 Univ Nagoya キノン誘導体
MX9203040A (es) * 1984-08-01 1992-07-31 Takeda Chemical Industries Ltd Derivados de quinona y composicion farmaceutica que los contiene.
EP0201196B1 (en) * 1985-04-08 1991-07-03 Takeda Chemical Industries, Ltd. Benzoquinone derivatives, their production and use
JP2503571B2 (ja) * 1988-02-26 1996-06-05 武田薬品工業株式会社 脳循環代謝改善剤
JPH08768B2 (ja) * 1989-08-24 1996-01-10 武田薬品工業株式会社 神経成長因子分泌誘導剤
RU1822549C (ru) * 1989-12-06 1996-08-20 Тихоокеанский институт биоорганической химии ДВО АН СССР Полигидрокси-1,4-нафтохиноны, обладающие свойством протектора миокарда при его ишемии и реперфузии
EP0560568A3 (en) * 1992-03-13 1994-06-29 Takeda Chemical Industries Ltd Hydroquinone derivatives and intermediates for production thereof
EP0643775B1 (en) * 1992-05-28 2004-07-21 Centre For Molecular Biology And Medicine, Quinone derivatives for enhancing cellular bioenergy
EP0788793A1 (en) 1996-02-01 1997-08-13 Takeda Chemical Industries, Ltd. Idebenone for the treatment of dementia
WO1999007355A1 (fr) * 1997-08-12 1999-02-18 Takeda Chemical Industries, Ltd. Preparation contenant de l'idebenone pour administration par voie percutanee
DE19932197A1 (de) 1999-07-09 2001-01-18 Neudecker Birgit Topisch anzuwendendes Mittel mit schützender und regenerativer Wirkung
US20050152857A1 (en) * 2004-01-08 2005-07-14 Pcr Technology Holdings, Lc Method and preparation for reducing sunburn cell formation in skin
US20050175559A1 (en) * 2004-02-10 2005-08-11 Pcr Technology Holdings, Lc Method and preparation for reducing skin hyperpigmentation
EP1651199A4 (en) * 2004-02-13 2008-08-20 Pcr Technology Holdings Lc PROCESS AND PREPARATION REDUCING IRRITATION AND / OR INFLAMMATORY SKIN REACTIONS IN HUMANS
EP1829536B1 (en) * 2004-11-25 2011-03-30 Meiji Dairies Corporation Ameliorant for renal insufficiency
DK2564843T3 (en) * 2005-06-01 2019-03-11 Bioelectron Tech Corp Redox-active therapeutics for the treatment of mitochondrial diseases and other conditions as well as modulation of energy biomarkers
PL1933821T3 (pl) * 2005-09-15 2021-01-11 Ptc Therapeutics, Inc. Warianty łańcucha końcowego środków terapeutycznych o aktywności redoks do leczenia chorób mitochondrialnych i innych stanów oraz do modulacji biomarkerów energetycznych
AR053665A1 (es) * 2006-01-23 2007-05-16 Creactivar S A Uso de la mimosina o un derivado de la misma, en el tratamiento de las manifestaciones cutaneas de la psoriasis y de los desordenes cutaneos relacionados con esta y una composicion cosmetica o farmaceutica que la comprende
JP5374162B2 (ja) 2006-02-22 2013-12-25 エジソン ファーマシューティカルズ, インコーポレイテッド ミトコンドリア病および他の症状の処置のためのレドックス活性化治療の側鎖変異体およびエネルギーバイオマーカーの調節
US8314153B2 (en) 2008-09-10 2012-11-20 Edison Pharmaceuticals, Inc. Treatment of pervasive developmental disorders with redox-active therapeutics
US20100129431A1 (en) * 2008-11-24 2010-05-27 Alpharx Inc. Idebenone composition for the treatment of neurological disorders
US20110159121A1 (en) * 2009-12-24 2011-06-30 LifeSpan Extension, LLC Methods and compositions for identifying, producing and using plant-derived products for modulating cell function and aging
US10017445B2 (en) 2012-07-12 2018-07-10 Concert Pharmaceuticals, Inc. Deuterated idebenone
CN108712903A (zh) 2015-12-17 2018-10-26 生物电子技术有限公司 用于治疗氧化应急障碍的氟烷基、氟代烷氧基、苯氧基、杂芳氧基、烷氧基和胺1,4-苯醌衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5919930B2 (ja) * 1974-05-02 1984-05-09 武田薬品工業株式会社 キノン酸誘導体の製造法
JPS51128932A (en) * 1975-04-30 1976-11-10 Takeda Chem Ind Ltd Organic compounds
EP0021841B1 (en) * 1979-06-28 1984-10-24 Takeda Chemical Industries, Ltd. 2,3-dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives

Also Published As

Publication number Publication date
HK64089A (en) 1989-08-18
MY8700652A (en) 1987-12-31
ATE21031T1 (de) 1986-08-15
DE3049039A1 (de) 1981-09-10
DE3071684D1 (en) 1986-09-04
JPS5697223A (en) 1981-08-05
EP0031727A3 (en) 1981-07-22
JPH0112727B2 (it) 1989-03-02
IT1144075B (it) 1986-10-29
US4436753A (en) 1984-03-13
EP0031727B1 (en) 1986-07-30
IT8050468A0 (it) 1980-12-24
EP0031727A2 (en) 1981-07-08

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