SG50625A1 - Thioxanthenone antitumor agents - Google Patents
Thioxanthenone antitumor agentsInfo
- Publication number
- SG50625A1 SG50625A1 SG1996007125A SG1996007125A SG50625A1 SG 50625 A1 SG50625 A1 SG 50625A1 SG 1996007125 A SG1996007125 A SG 1996007125A SG 1996007125 A SG1996007125 A SG 1996007125A SG 50625 A1 SG50625 A1 SG 50625A1
- Authority
- SG
- Singapore
- Prior art keywords
- alkyl
- hydrogen
- ch2n
- antitumor agents
- thioxanthenones
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- YRHRIQCWCFGUEQ-UHFFFAOYSA-N thioxanthen-9-one Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3SC2=C1 YRHRIQCWCFGUEQ-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004005 formimidoyl group Chemical group [H]\N=C(/[H])* 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical group [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655363—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
- C07F9/655372—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C07D335/14—Thioxanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D335/16—Oxygen atoms, e.g. thioxanthones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71317391A | 1991-06-10 | 1991-06-10 | |
| US83515992A | 1992-02-13 | 1992-02-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG50625A1 true SG50625A1 (en) | 1998-07-20 |
Family
ID=27108950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG1996007125A SG50625A1 (en) | 1991-06-10 | 1992-06-03 | Thioxanthenone antitumor agents |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0518414B1 (no) |
| JP (1) | JP3045354B2 (no) |
| KR (1) | KR100209826B1 (no) |
| AT (1) | ATE106882T1 (no) |
| AU (1) | AU642596B2 (no) |
| CA (1) | CA2070120C (no) |
| DE (1) | DE69200179T2 (no) |
| DK (1) | DK0518414T3 (no) |
| ES (1) | ES2055635T3 (no) |
| FI (1) | FI114024B (no) |
| HU (1) | HU218655B (no) |
| IE (1) | IE66828B1 (no) |
| IL (1) | IL102139A (no) |
| MX (1) | MX9202753A (no) |
| NO (1) | NO302364B1 (no) |
| NZ (1) | NZ242862A (no) |
| PH (1) | PH30883A (no) |
| RU (1) | RU2075477C1 (no) |
| SG (1) | SG50625A1 (no) |
| TW (1) | TW218015B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5091410A (en) * | 1991-06-10 | 1992-02-25 | Sterling Winthrop Inc. | Thioxanthenone antitumor agents |
| US5346917A (en) * | 1991-06-10 | 1994-09-13 | Sterling Winthrop Inc. | Thioxanthenone antitumor agents |
| US5665760A (en) * | 1995-09-18 | 1997-09-09 | Sanofi Winthrop, Inc. | Lyophilized thioxanthenone antitumor agents |
| EP2175854A4 (en) | 2007-07-31 | 2012-02-29 | Univ North Dakota Res Foundation | IMPROVED METHOD FOR THE SYNTHESIS OF SUBSTITUTED FORMYLAMINES AND SUBSTITUTED AMINES |
| FR2979823B1 (fr) * | 2011-09-13 | 2013-09-27 | Pf Medicament | Utilisation du 3-(r)-[3-(2-methoxyphenylthio)-2-(s)-methyl-propyl]amino-3,4-dihydro-2h-1,5-benzoxathiepine pour le traitement du cancer et en particulier pour la prevention et/ou le traitement des metastases cancereuses |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3745172A (en) * | 1970-10-05 | 1973-07-10 | Sterling Drug Inc | 1-(di-(lower-alkyl)aminoalkylamino)-9-oxothioxanthenes |
| US4539412A (en) * | 1982-07-08 | 1985-09-03 | Rensselaer Polytechnic Institute | 7-Hydroxylucanthone, 7-hydroxhycanthone and their analogs |
| US5091410A (en) * | 1991-06-10 | 1992-02-25 | Sterling Winthrop Inc. | Thioxanthenone antitumor agents |
-
1992
- 1992-05-21 AU AU17046/92A patent/AU642596B2/en not_active Ceased
- 1992-05-22 NZ NZ242862A patent/NZ242862A/xx not_active IP Right Cessation
- 1992-06-01 CA CA002070120A patent/CA2070120C/en not_active Expired - Fee Related
- 1992-06-03 EP EP92201587A patent/EP0518414B1/en not_active Expired - Lifetime
- 1992-06-03 DK DK92201587.0T patent/DK0518414T3/da active
- 1992-06-03 SG SG1996007125A patent/SG50625A1/en unknown
- 1992-06-03 DE DE69200179T patent/DE69200179T2/de not_active Expired - Fee Related
- 1992-06-03 TW TW081104387A patent/TW218015B/zh active
- 1992-06-03 ES ES92201587T patent/ES2055635T3/es not_active Expired - Lifetime
- 1992-06-03 AT AT92201587T patent/ATE106882T1/de not_active IP Right Cessation
- 1992-06-08 JP JP4147101A patent/JP3045354B2/ja not_active Expired - Fee Related
- 1992-06-09 RU SU925052026A patent/RU2075477C1/ru not_active IP Right Cessation
- 1992-06-09 MX MX9202753A patent/MX9202753A/es not_active IP Right Cessation
- 1992-06-09 KR KR1019920009956A patent/KR100209826B1/ko not_active IP Right Cessation
- 1992-06-09 IL IL102139A patent/IL102139A/xx not_active IP Right Cessation
- 1992-06-10 FI FI922694A patent/FI114024B/fi not_active IP Right Cessation
- 1992-06-10 PH PH44488A patent/PH30883A/en unknown
- 1992-06-10 NO NO922273A patent/NO302364B1/no unknown
- 1992-06-10 HU HU9201926A patent/HU218655B/hu not_active IP Right Cessation
- 1992-07-01 IE IE921871A patent/IE66828B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TW218015B (no) | 1993-12-21 |
| ES2055635T3 (es) | 1994-08-16 |
| PH30883A (en) | 1997-12-23 |
| AU1704692A (en) | 1992-12-17 |
| DE69200179T2 (de) | 1995-01-19 |
| NZ242862A (en) | 1993-09-27 |
| NO922273L (no) | 1992-12-11 |
| FI114024B (fi) | 2004-07-30 |
| CA2070120C (en) | 2005-11-15 |
| EP0518414B1 (en) | 1994-06-08 |
| DE69200179D1 (de) | 1994-07-14 |
| JP3045354B2 (ja) | 2000-05-29 |
| FI922694A0 (fi) | 1992-06-10 |
| IE921871A1 (en) | 1992-12-16 |
| JPH05178853A (ja) | 1993-07-20 |
| IE66828B1 (en) | 1996-02-07 |
| KR100209826B1 (ko) | 1999-07-15 |
| ATE106882T1 (de) | 1994-06-15 |
| MX9202753A (es) | 1993-01-01 |
| HUT61992A (en) | 1993-03-29 |
| NO302364B1 (no) | 1998-02-23 |
| KR930000499A (ko) | 1993-01-15 |
| AU642596B2 (en) | 1993-10-21 |
| EP0518414A1 (en) | 1992-12-16 |
| IL102139A (en) | 1997-03-18 |
| IL102139A0 (en) | 1993-01-14 |
| RU2075477C1 (ru) | 1997-03-20 |
| CA2070120A1 (en) | 1992-12-11 |
| FI922694A (fi) | 1992-12-11 |
| HU9201926D0 (en) | 1992-08-28 |
| NO922273D0 (no) | 1992-06-10 |
| DK0518414T3 (da) | 1994-08-15 |
| HU218655B (hu) | 2000-10-28 |
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