SG189234A1 - Formulations and methods for attenuating respiratory depression induced by opioid overdose - Google Patents
Formulations and methods for attenuating respiratory depression induced by opioid overdose Download PDFInfo
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- SG189234A1 SG189234A1 SG2013024583A SG2013024583A SG189234A1 SG 189234 A1 SG189234 A1 SG 189234A1 SG 2013024583 A SG2013024583 A SG 2013024583A SG 2013024583 A SG2013024583 A SG 2013024583A SG 189234 A1 SG189234 A1 SG 189234A1
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- Singapore
- Prior art keywords
- naltrexone
- opioid
- formulation
- respiratory depression
- dose
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US40675210P | 2010-10-26 | 2010-10-26 | |
| PCT/IB2011/054767 WO2012056402A2 (en) | 2010-10-26 | 2011-10-25 | Formulations and methods for attenuating respiratory depression induced by opioid overdose |
Publications (1)
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| SG189234A1 true SG189234A1 (en) | 2013-05-31 |
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| SG2013024583A SG189234A1 (en) | 2010-10-26 | 2011-10-25 | Formulations and methods for attenuating respiratory depression induced by opioid overdose |
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| JP (1) | JP2013540807A (enExample) |
| KR (3) | KR20170102571A (enExample) |
| CN (1) | CN103189055A (enExample) |
| AU (1) | AU2011322147A1 (enExample) |
| BR (1) | BR112013009267A2 (enExample) |
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| RU (1) | RU2541159C2 (enExample) |
| SG (1) | SG189234A1 (enExample) |
| WO (1) | WO2012056402A2 (enExample) |
| ZA (1) | ZA201302363B (enExample) |
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| AU776666B2 (en) | 2000-02-08 | 2004-09-16 | Euro-Celtique S.A. | Tamper-resistant oral opioid agonist formulations |
| US20110104214A1 (en) | 2004-04-15 | 2011-05-05 | Purdue Pharma L.P. | Once-a-day oxycodone formulations |
| CN103189055A (zh) * | 2010-10-26 | 2013-07-03 | 雅来制药有限责任公司 | 用于缓解阿片类物质用药过量引起的呼吸抑制的制剂和方法 |
| KR20130124551A (ko) * | 2011-02-02 | 2013-11-14 | 알파마 파머슈티컬스 엘엘씨 | 오피오이드 효능제 및 격리된 길항제를 포함하는 제약 조성물 |
| WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| US9549909B2 (en) | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
| US9943513B1 (en) | 2015-10-07 | 2018-04-17 | Banner Life Sciences Llc | Opioid abuse deterrent dosage forms |
| EP3800177B1 (en) | 2015-12-22 | 2025-01-29 | Zogenix International Limited | Fenfluramine compositions and methods of preparing the same |
| JP2019507111A (ja) | 2015-12-22 | 2019-03-14 | ゾゲニクス インターナショナル リミテッド | 代謝抵抗性フェンフルラミン類縁体およびその使用法 |
| WO2017180659A1 (en) * | 2016-04-11 | 2017-10-19 | Arizona Board Of Regents On Behalf Of University Of Arizona | Opioid receptor modulators |
| US10335405B1 (en) | 2016-05-04 | 2019-07-02 | Patheon Softgels, Inc. | Non-burst releasing pharmaceutical composition |
| RU2021106383A (ru) | 2016-08-24 | 2021-04-05 | Зодженикс Интернэшнл Лимитед | Состав для ингибирования образования агонистов 5-ht2b и способы его применения |
| US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
| US10682317B2 (en) | 2017-09-26 | 2020-06-16 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
| KR102810926B1 (ko) | 2017-12-20 | 2025-05-22 | 퍼듀 퍼머 엘피 | 남용 억제 황산모르핀 제형 |
| WO2019216919A1 (en) | 2018-05-11 | 2019-11-14 | Zogenix International Limited | Compositions and methods for treating seizure-induced sudden death |
| EP3806835A1 (en) * | 2018-06-14 | 2021-04-21 | Zogenix International Limited | Compositions and methods for treating respiratory depression with fenfluramine |
| EA202191079A1 (ru) | 2018-11-19 | 2021-09-20 | Зодженикс Интернэшнл Лимитед | Способы лечения синдрома ретта с применением фенфлурамина |
| WO2021072055A1 (en) * | 2019-10-11 | 2021-04-15 | Board Of Regents, The University Of Texas System | Compositions and methods for preventing, reducing and reversing opioid-induced respiratory depression |
| US20230063876A1 (en) * | 2020-03-02 | 2023-03-02 | Unm Rainforest Innovations | Virus-Like Particle Vaccines for Opioid Drugs |
| US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
| CN118488840A (zh) | 2021-11-02 | 2024-08-13 | 依那拉治疗股份有限公司 | 治疗由非阿片样药剂调节的呼吸抑制的方法 |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
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| WO2003013525A1 (en) * | 2001-08-06 | 2003-02-20 | Euro-Celtique S.A. | Opioid agonist formulations with releasable and sequestered antagonist |
| NZ547851A (en) * | 2003-12-05 | 2010-03-26 | Carefusion 303 Inc | Patient-controlled analgesia with patient monitoring system |
| EP1931593A4 (en) | 2005-10-07 | 2009-04-22 | Univ Florida | MULTIPLE COMPONENT NANOPARTICLES FOR MULTIPLEX SIGNALING AND OPTICAL CODING |
| CA2665726C (en) * | 2006-10-11 | 2016-04-19 | Alpharma, Inc. | Pharmaceutical compositions |
| EP2197427A2 (en) * | 2007-09-04 | 2010-06-23 | Alpharma, Inc. | A multilayer pharmaceutical composition comprising an antagonist in a first layer and an agonist in a second layer |
| US20090196890A1 (en) * | 2007-12-17 | 2009-08-06 | Alpharma Pharmaceuticals, Llc | Pharmaceutical compositions |
| US8623418B2 (en) * | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
| IT1391530B1 (it) | 2008-07-31 | 2012-01-11 | Cyanagen S R L | Particelle attive per applicazioni bio-analitiche e metodi per la loro preparazione |
| US8771642B2 (en) | 2008-07-31 | 2014-07-08 | Alma Mater Studiorum—Universita' di Bologna | Active particles for bio-analytical applications and methods for their preparation |
| CN103189055A (zh) * | 2010-10-26 | 2013-07-03 | 雅来制药有限责任公司 | 用于缓解阿片类物质用药过量引起的呼吸抑制的制剂和方法 |
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2011
- 2011-10-25 CN CN201180051633XA patent/CN103189055A/zh active Pending
- 2011-10-25 KR KR1020177024247A patent/KR20170102571A/ko not_active Ceased
- 2011-10-25 US US13/881,758 patent/US20140030343A1/en not_active Abandoned
- 2011-10-25 JP JP2013535564A patent/JP2013540807A/ja active Pending
- 2011-10-25 BR BR112013009267A patent/BR112013009267A2/pt not_active IP Right Cessation
- 2011-10-25 RU RU2013117274/15A patent/RU2541159C2/ru not_active IP Right Cessation
- 2011-10-25 MX MX2013003832A patent/MX2013003832A/es not_active Application Discontinuation
- 2011-10-25 EP EP11807744.5A patent/EP2632442A2/en not_active Withdrawn
- 2011-10-25 KR KR1020137010558A patent/KR20130097211A/ko not_active Ceased
- 2011-10-25 KR KR1020167003000A patent/KR20160017668A/ko not_active Ceased
- 2011-10-25 WO PCT/IB2011/054767 patent/WO2012056402A2/en not_active Ceased
- 2011-10-25 SG SG2013024583A patent/SG189234A1/en unknown
- 2011-10-25 CA CA2814230A patent/CA2814230A1/en not_active Abandoned
- 2011-10-25 AU AU2011322147A patent/AU2011322147A1/en not_active Abandoned
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2013
- 2013-04-02 ZA ZA2013/02363A patent/ZA201302363B/en unknown
- 2013-04-25 IL IL225966A patent/IL225966A0/en unknown
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2015
- 2015-10-26 US US14/922,474 patent/US20160045449A1/en not_active Abandoned
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2017
- 2017-04-27 US US15/498,617 patent/US20170367987A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20170102571A (ko) | 2017-09-11 |
| RU2541159C2 (ru) | 2015-02-10 |
| CA2814230A1 (en) | 2012-05-03 |
| RU2013117274A (ru) | 2014-12-10 |
| KR20160017668A (ko) | 2016-02-16 |
| ZA201302363B (en) | 2014-06-25 |
| US20140030343A1 (en) | 2014-01-30 |
| MX2013003832A (es) | 2013-10-01 |
| EP2632442A2 (en) | 2013-09-04 |
| KR20130097211A (ko) | 2013-09-02 |
| AU2011322147A1 (en) | 2013-04-18 |
| CN103189055A (zh) | 2013-07-03 |
| WO2012056402A2 (en) | 2012-05-03 |
| IL225966A0 (en) | 2013-06-27 |
| US20170367987A1 (en) | 2017-12-28 |
| WO2012056402A3 (en) | 2012-10-04 |
| JP2013540807A (ja) | 2013-11-07 |
| BR112013009267A2 (pt) | 2016-07-26 |
| US20160045449A1 (en) | 2016-02-18 |
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