SG182229A1 - Therapeutic compositions and the use thereof - Google Patents
Therapeutic compositions and the use thereof Download PDFInfo
- Publication number
- SG182229A1 SG182229A1 SG2012046934A SG2012046934A SG182229A1 SG 182229 A1 SG182229 A1 SG 182229A1 SG 2012046934 A SG2012046934 A SG 2012046934A SG 2012046934 A SG2012046934 A SG 2012046934A SG 182229 A1 SG182229 A1 SG 182229A1
- Authority
- SG
- Singapore
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound
- ugt
- inhibits
- Prior art date
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Applications Claiming Priority (2)
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| SG170795A1 (en) * | 2005-12-30 | 2011-05-30 | Gilead Sciences Inc | Methods for improving the pharmacokinetics of hiv integrase inhibitors |
| AP2985A (en) | 2006-07-07 | 2014-09-30 | Gilead Sciences Inc | Modulators of pharmacokinetic properties of therapeutics |
| CA2661943C (en) | 2006-09-12 | 2015-11-03 | Gilead Sciences, Inc. | Process and intermediates for preparing integrase inhibitors |
| LT2487163T (lt) * | 2007-02-23 | 2016-10-25 | Gilead Sciences, Inc. | Terapinių agentų farmakokinetinių savybių moduliatoriai |
| EP2167088A1 (en) * | 2007-06-29 | 2010-03-31 | Gilead Sciences, Inc. | Therapeutic compositions and the use thereof |
| JP5547067B2 (ja) * | 2007-06-29 | 2014-07-09 | ギリアード サイエンシーズ， インコーポレイテッド | 治療組成物およびその使用 |
| AR068403A1 (es) * | 2007-09-11 | 2009-11-18 | Gilead Sciences Inc | Proceso e intermediarios para la preparacion de inhibidores de integrasa |
| BRPI0911871A8 (pt) | 2008-05-02 | 2018-03-06 | Gilead Sciences Inc | uso de partículas veículo sólidas para melhorar a processabilidade de um agente farmacêutico |
| WO2011127244A2 (en) * | 2010-04-09 | 2011-10-13 | Bristol-Myers Squibb Company | ATAZANAVIR SULFATE FORMULATIONS WITH IMPROVED pH EFFECT |
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| CA2856722C (en) | 2011-11-30 | 2022-11-22 | Emory University | Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections |
| EA026089B1 (ru) | 2012-08-03 | 2017-02-28 | Джилид Сайэнс, Инк. | Способ и промежуточные соединения для получения ингибиторов интегразы |
| AU2013361401C1 (en) | 2012-12-21 | 2018-08-09 | Gilead Sciences, Inc. | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use |
| NO2865735T3 (OSRAM) | 2013-07-12 | 2018-07-21 | ||
| PL3019503T3 (pl) | 2013-07-12 | 2018-01-31 | Gilead Sciences Inc | Policykliczne związki karbamoilopirydonowe i ich zastosowanie do leczenia infekcji hiv |
| US9463194B2 (en) | 2014-02-05 | 2016-10-11 | Gilead Sciences, Inc. | Methods of treating patients co-infected with HIV and tuberculosis |
| TWI677489B (zh) | 2014-06-20 | 2019-11-21 | 美商基利科學股份有限公司 | 多環型胺甲醯基吡啶酮化合物之合成 |
| TW201613936A (en) | 2014-06-20 | 2016-04-16 | Gilead Sciences Inc | Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide |
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| TWI738321B (zh) | 2014-12-23 | 2021-09-01 | 美商基利科學股份有限公司 | 多環胺甲醯基吡啶酮化合物及其醫藥用途 |
| CN118286245A (zh) | 2014-12-26 | 2024-07-05 | 埃莫里大学 | N4-羟基胞苷和衍生物及与其相关的抗病毒用途 |
| CN110790773A (zh) | 2015-04-02 | 2020-02-14 | 吉利德科学公司 | 多环氨甲酰基吡啶酮化合物及其药物用途 |
| US11331331B2 (en) | 2017-12-07 | 2022-05-17 | Emory University | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
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| US5539122A (en) * | 1989-05-23 | 1996-07-23 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| GB8927913D0 (en) * | 1989-12-11 | 1990-02-14 | Hoffmann La Roche | Amino acid derivatives |
| US5413999A (en) * | 1991-11-08 | 1995-05-09 | Merck & Co., Inc. | HIV protease inhibitors useful for the treatment of AIDS |
| US5484926A (en) * | 1993-10-07 | 1996-01-16 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors |
| US5914332A (en) * | 1995-12-13 | 1999-06-22 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| US5849911A (en) * | 1996-04-22 | 1998-12-15 | Novartis Finance Corporation | Antivirally active heterocyclic azahexane derivatives |
| US6087383A (en) * | 1998-01-20 | 2000-07-11 | Bristol-Myers Squibb Company | Bisulfate salt of HIV protease inhibitor |
| US6544540B2 (en) * | 1998-07-29 | 2003-04-08 | Syngenta Limited | Base-triggered release microcapsules |
| SI1564210T1 (sl) * | 2002-11-20 | 2010-01-29 | Japan Tobacco Inc | 4-oksokinolinske spojine in njihova uporaba kot inhibitorji HIV integraze |
| MY134672A (en) * | 2004-05-20 | 2007-12-31 | Japan Tobacco Inc | Stable crystal of 4-oxoquinoline compound |
| EP2332538A1 (en) * | 2004-05-21 | 2011-06-15 | Japan Tobacco, Inc. | Combinations comprising a 4-isoquinolone derivative and anti-HIV agents |
| US20060058286A1 (en) * | 2004-09-16 | 2006-03-16 | Mark Krystal | Methods of treating HIV infection |
| SG170795A1 (en) * | 2005-12-30 | 2011-05-30 | Gilead Sciences Inc | Methods for improving the pharmacokinetics of hiv integrase inhibitors |
| US20090233964A1 (en) * | 2005-12-30 | 2009-09-17 | Gilead Sciences, Inc. | Methods for improving the pharmacokinetics of hiv integrase inhibitors |
| AP2985A (en) * | 2006-07-07 | 2014-09-30 | Gilead Sciences Inc | Modulators of pharmacokinetic properties of therapeutics |
| CA2661943C (en) * | 2006-09-12 | 2015-11-03 | Gilead Sciences, Inc. | Process and intermediates for preparing integrase inhibitors |
| JP5547067B2 (ja) * | 2007-06-29 | 2014-07-09 | ギリアード サイエンシーズ， インコーポレイテッド | 治療組成物およびその使用 |
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| BRPI0911871A8 (pt) * | 2008-05-02 | 2018-03-06 | Gilead Sciences Inc | uso de partículas veículo sólidas para melhorar a processabilidade de um agente farmacêutico |
| US20110000941A1 (en) * | 2009-07-06 | 2011-01-06 | Volk J Patrick | Apparatus and System for Carrying a Digital Media Player |
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- 2008-06-26 NZ NZ582086A patent/NZ582086A/en not_active IP Right Cessation
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- 2008-06-26 KR KR1020107001981A patent/KR20100040892A/ko not_active Ceased
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- 2008-06-26 SG SG2012046934A patent/SG182229A1/en unknown
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- 2008-06-26 AU AU2008270630A patent/AU2008270630B2/en not_active Ceased
- 2008-06-26 WO PCT/US2008/068339 patent/WO2009006199A1/en not_active Ceased
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|---|---|
| BRPI0813000A2 (pt) | 2014-12-23 |
| CN101686972A (zh) | 2010-03-31 |
| NZ582086A (en) | 2012-07-27 |
| EP2167088A1 (en) | 2010-03-31 |
| EA200971093A1 (ru) | 2010-08-30 |
| AU2008270630B2 (en) | 2014-01-16 |
| AP2009005074A0 (en) | 2009-12-31 |
| JP5547066B2 (ja) | 2014-07-09 |
| CN103480000A (zh) | 2014-01-01 |
| CO6251237A2 (es) | 2011-02-21 |
| IL202744A0 (en) | 2010-06-30 |
| US20090093467A1 (en) | 2009-04-09 |
| TW200914011A (en) | 2009-04-01 |
| US20100331331A1 (en) | 2010-12-30 |
| MX2009013829A (es) | 2010-03-10 |
| KR20100040892A (ko) | 2010-04-21 |
| WO2009006199A1 (en) | 2009-01-08 |
| CA2692101A1 (en) | 2009-01-08 |
| AR067183A1 (es) | 2009-09-30 |
| AU2008270630A1 (en) | 2009-01-08 |
| JP2010532372A (ja) | 2010-10-07 |
| JP5769763B2 (ja) | 2015-08-26 |
| AP2965A (en) | 2014-09-30 |
| JP2015143278A (ja) | 2015-08-06 |
| JP2013199495A (ja) | 2013-10-03 |
| CN101686972B (zh) | 2013-08-14 |
| US20170136001A1 (en) | 2017-05-18 |
| US20140343063A1 (en) | 2014-11-20 |
| ECSP109897A (es) | 2010-03-31 |
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