SG181856A1 - Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (pgl) - Google Patents

Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (pgl) Download PDF

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Publication number
SG181856A1
SG181856A1 SG2012045902A SG2012045902A SG181856A1 SG 181856 A1 SG181856 A1 SG 181856A1 SG 2012045902 A SG2012045902 A SG 2012045902A SG 2012045902 A SG2012045902 A SG 2012045902A SG 181856 A1 SG181856 A1 SG 181856A1
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Singapore
Prior art keywords
polypeptide
aspects
coli
isoprene
pgl
Prior art date
Application number
SG2012045902A
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English (en)
Inventor
Zachary Q Beck
Marguerite A Cervin
Alex T Nielsen
Caroline M Peres
Original Assignee
Danisco Us Inc
Good Year Tire & Rubber Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc, Good Year Tire & Rubber Company filed Critical Danisco Us Inc
Publication of SG181856A1 publication Critical patent/SG181856A1/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Tires In General (AREA)
SG2012045902A 2009-12-23 2010-12-23 Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (pgl) SG181856A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28995909P 2009-12-23 2009-12-23
PCT/US2010/062099 WO2011079314A2 (en) 2009-12-23 2010-12-23 Compositions and methods of pgl for the increased production of isoprene

Publications (1)

Publication Number Publication Date
SG181856A1 true SG181856A1 (en) 2012-07-30

Family

ID=43971157

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2012045902A SG181856A1 (en) 2009-12-23 2010-12-23 Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (pgl)
SG2014000111A SG196782A1 (en) 2009-12-23 2010-12-23 Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (pgl)

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2014000111A SG196782A1 (en) 2009-12-23 2010-12-23 Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (pgl)

Country Status (10)

Country Link
US (3) US8455236B2 (zh)
EP (2) EP2857518A3 (zh)
JP (1) JP5706444B2 (zh)
CN (1) CN102906268A (zh)
AU (1) AU2010336342B2 (zh)
BR (1) BR112012017345A2 (zh)
CA (1) CA2785480A1 (zh)
HK (1) HK1178207A1 (zh)
SG (2) SG181856A1 (zh)
WO (1) WO2011079314A2 (zh)

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CA2748887A1 (en) 2008-12-30 2010-07-08 Danisco Us Inc. Methods of producing isoprene and a co-product
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CN103443271A (zh) 2010-10-27 2013-12-11 丹尼斯科美国公司 用于增加异戊二烯产量的异戊二烯合酶变体
ES2699747T3 (es) * 2011-04-29 2019-02-12 Danisco Us Inc Microorganismos recombinantes para la producción potenciada de mevalonato, isopreno e isoprenoides
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CN107254492A (zh) 2011-06-17 2017-10-17 英威达技术有限责任公司 产生1,3‑丁二烯的方法
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
AU2012289886A1 (en) * 2011-08-04 2014-02-20 Danisco Us Inc. Production of isoprene, isoprenoid precursors, and isoprenoids using acetoacetyl-CoA synthase
US8951764B2 (en) 2011-08-05 2015-02-10 Danisco Us Inc. Production of isoprenoids under neutral pH conditions
DK2764084T4 (da) 2011-10-07 2021-12-06 Danisco Us Inc Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer, og isopren
BR112014010053A8 (pt) 2011-10-27 2017-06-20 Danisco Us Inc variantes de isopreno sintase com solubilidade aprimorada para produção de isopreno
EP2794863A1 (en) 2011-12-23 2014-10-29 Danisco US Inc. Enhanced production of isoprene using host cells having decreased ispa activity
WO2013096863A1 (en) * 2011-12-23 2013-06-27 The Regents Of The University Of California Constructs and methods for improved isoprene biosynthesis
WO2013119340A1 (en) * 2012-02-08 2013-08-15 Glycos Biotechnologies, Inc. Microorganism and process for isoprene production
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene
US8895277B2 (en) 2012-05-02 2014-11-25 Danisco Us Inc. Legume isoprene synthase for production of isoprene
JP2015516173A (ja) * 2012-05-16 2015-06-11 グリコス バイオテクノロジーズ インコーポレイテッドGlycos Biotechnologies, Inc. イソプレン生産用微生物およびプロセス
CN104903455A (zh) 2012-11-28 2015-09-09 英威达技术有限责任公司 用于异丁烯生物合成的方法
EP2935364A2 (en) 2012-12-21 2015-10-28 Danisco US Inc. Production of isoprene, isoprenoid, and isoprenoid precursors using an alternative lower mevalonate pathway
WO2014156997A1 (ja) * 2013-03-29 2014-10-02 味の素株式会社 発酵ガス中のイソプレンの回収方法および精製イソプレンの製造方法
ES2735331T3 (es) 2013-04-10 2019-12-18 Goodyear Tire & Rubber Fosfocetolasas para mejorar la producción de metabolitos derivados de acetil-coenzima A, isopreno, precursores de isoprenoides e isoprenoides
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
WO2015021059A1 (en) 2013-08-05 2015-02-12 INVISTA North America S.á r.l. Methods for biosynthesis of isobutene
EP3030667A2 (en) 2013-08-05 2016-06-15 Invista Technologies S.a r.l. Methods for biosynthesis of isoprene
US10648004B2 (en) 2014-02-20 2020-05-12 Danisco Us Inc. Recombinant microorganisms for the enhanced production of mevalonate, isoprene, isoprenoid precursors, isoprenoids, and acetyl-CoA-derived products
US20170152531A1 (en) 2014-06-16 2017-06-01 North America S.A.R.L. Process for producing glutarate and glutaric acid methyl ester
CN107916274B (zh) * 2016-10-11 2020-09-18 华东理工大学 通过调节碳代谢途径基因提高s-腺苷甲硫氨酸产量的方法
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
CN109295087B (zh) * 2018-11-09 2021-08-24 沈阳农业大学 一种表达制备udp-葡萄糖-己糖-1-磷酸尿苷酰转移酶的方法
CN112175986B (zh) * 2020-09-15 2021-06-01 广东省农业科学院蔬菜研究所 黄瓜6-磷酸葡萄糖酸内酯酶CsPmR1在抗瓜类疫病中的应用
CN115747127B (zh) * 2022-11-24 2024-08-23 中国科学院青岛生物能源与过程研究所 一种高产西柏三烯一醇产量的工程菌及其构建方法与应用

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Also Published As

Publication number Publication date
JP5706444B2 (ja) 2015-04-22
HK1178207A1 (zh) 2013-09-06
US8889387B2 (en) 2014-11-18
WO2011079314A3 (en) 2011-08-18
US20150104853A1 (en) 2015-04-16
EP2516654A2 (en) 2012-10-31
AU2010336342B2 (en) 2015-02-26
JP2013515491A (ja) 2013-05-09
US20130295633A1 (en) 2013-11-07
AU2010336342A1 (en) 2012-07-05
WO2011079314A8 (en) 2012-07-05
CN102906268A (zh) 2013-01-30
US20110159557A1 (en) 2011-06-30
EP2857518A3 (en) 2015-04-22
EP2857518A2 (en) 2015-04-08
SG196782A1 (en) 2014-02-13
US8455236B2 (en) 2013-06-04
WO2011079314A2 (en) 2011-06-30
EP2516654B1 (en) 2015-01-21
BR112012017345A2 (pt) 2015-11-03
CA2785480A1 (en) 2011-06-30
US9353375B2 (en) 2016-05-31

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