SG175032A1 - Therapeutic agents for the treatment of diseases associated with undesired cell proliferation - Google Patents

Therapeutic agents for the treatment of diseases associated with undesired cell proliferation Download PDF

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Publication number
SG175032A1
SG175032A1 SG2011071834A SG2011071834A SG175032A1 SG 175032 A1 SG175032 A1 SG 175032A1 SG 2011071834 A SG2011071834 A SG 2011071834A SG 2011071834 A SG2011071834 A SG 2011071834A SG 175032 A1 SG175032 A1 SG 175032A1
Authority
SG
Singapore
Prior art keywords
cancer
type cytokine
lif
cell proliferation
cytokine
Prior art date
Application number
SG2011071834A
Other languages
English (en)
Inventor
Suarez Joan Seoane
Prieto Silvia Penuelas
Torres Jose Baselga
Original Assignee
Fundacio Privada Institucio Catalana De Recerca I Estudis Avancats Icrea
Fundacio Privada Inst D Invesigacio Oncologica Vall D Hebron Vhio
Fundacio Privada Inst De Recerca Hospital Uni Vall Hebron Ir Huvh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacio Privada Institucio Catalana De Recerca I Estudis Avancats Icrea, Fundacio Privada Inst D Invesigacio Oncologica Vall D Hebron Vhio, Fundacio Privada Inst De Recerca Hospital Uni Vall Hebron Ir Huvh filed Critical Fundacio Privada Institucio Catalana De Recerca I Estudis Avancats Icrea
Publication of SG175032A1 publication Critical patent/SG175032A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2093Leukaemia inhibitory factor [LIF]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/248IL-6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7125Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
SG2011071834A 2009-04-03 2010-04-06 Therapeutic agents for the treatment of diseases associated with undesired cell proliferation SG175032A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200900928A ES2363358B1 (es) 2009-04-03 2009-04-03 Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable.
PCT/EP2010/054499 WO2010115868A2 (en) 2009-04-03 2010-04-06 Therapeutic agents for the treatment of diseases associated with undesired cell proliferation

Publications (1)

Publication Number Publication Date
SG175032A1 true SG175032A1 (en) 2011-11-28

Family

ID=42342718

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2011071834A SG175032A1 (en) 2009-04-03 2010-04-06 Therapeutic agents for the treatment of diseases associated with undesired cell proliferation
SG10202010568RA SG10202010568RA (en) 2009-04-03 2010-04-06 Therapeutic Agents For The Treatment Of Diseases Associated With Undesired Cell Proliferation

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10202010568RA SG10202010568RA (en) 2009-04-03 2010-04-06 Therapeutic Agents For The Treatment Of Diseases Associated With Undesired Cell Proliferation

Country Status (24)

Country Link
US (4) US10100112B2 (cg-RX-API-DMAC7.html)
EP (2) EP2414394A2 (cg-RX-API-DMAC7.html)
JP (5) JP6207836B2 (cg-RX-API-DMAC7.html)
KR (6) KR20190093691A (cg-RX-API-DMAC7.html)
CN (2) CN102574918A (cg-RX-API-DMAC7.html)
AU (1) AU2010233791B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI1015369A2 (cg-RX-API-DMAC7.html)
CA (1) CA2757680C (cg-RX-API-DMAC7.html)
CY (1) CY1124148T1 (cg-RX-API-DMAC7.html)
DK (1) DK3045474T3 (cg-RX-API-DMAC7.html)
EA (1) EA201101450A1 (cg-RX-API-DMAC7.html)
ES (2) ES2363358B1 (cg-RX-API-DMAC7.html)
HR (1) HRP20210352T1 (cg-RX-API-DMAC7.html)
HU (1) HUE054196T2 (cg-RX-API-DMAC7.html)
IL (1) IL215467A (cg-RX-API-DMAC7.html)
LT (1) LT3045474T (cg-RX-API-DMAC7.html)
MX (1) MX336903B (cg-RX-API-DMAC7.html)
PL (1) PL3045474T3 (cg-RX-API-DMAC7.html)
PT (1) PT3045474T (cg-RX-API-DMAC7.html)
SG (2) SG175032A1 (cg-RX-API-DMAC7.html)
SI (1) SI3045474T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202100153T1 (cg-RX-API-DMAC7.html)
WO (1) WO2010115868A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201107215B (cg-RX-API-DMAC7.html)

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JP2015071566A (ja) * 2013-10-03 2015-04-16 住友ベークライト株式会社 Fgf4遺伝子増幅腫瘍の医薬組成物
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CN106659775B (zh) * 2014-06-30 2021-08-06 阿尔托生物科学有限公司 基于il-15的分子及其方法和用途
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WO2018115960A1 (en) 2016-12-19 2018-06-28 Mosaic Biomedicals, S.L. Antibodies against lif and uses thereof
KR102716931B1 (ko) 2016-12-19 2024-10-15 펀다시오 프리바다 인스티튜시오 카탈라나 드 르세르카 아이 에스투디스 아반카츠 Lif에 대한 항체 및 이의 용도
KR20210008514A (ko) * 2018-05-14 2021-01-22 메디뮨 리미티드 Lif에 대한 항체 및 이의 투여 형태
JP7379390B2 (ja) * 2018-06-18 2023-11-14 メドイミューン・リミテッド 癌の治療に使用するためのlif阻害剤と白金系抗悪性腫瘍剤の組み合わせ
AU2019291305B2 (en) * 2018-06-18 2024-03-21 Fundacio Privada Institucio Catalana de Recerca i Estudis Avancats Methods for improving response to anti-LIF antibody treatment in individuals with cancer
WO2020056349A2 (en) * 2018-09-13 2020-03-19 Evestra, Inc. Lif/lifr antagonist oncology and nonmalignant diseases
CA3135694A1 (en) * 2019-04-17 2020-10-22 Hiroshima University Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination
CN111020030A (zh) * 2019-12-03 2020-04-17 中山大学 一种骨肉瘤干细胞标志物及其应用、试剂盒
EP3988116A1 (en) * 2020-10-23 2022-04-27 Consejo Superior De Investigaciones Científicas (CSIC) Methods and compositions for the treatment of hematologic malignancies

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Also Published As

Publication number Publication date
EA201101450A1 (ru) 2012-04-30
US20200385455A1 (en) 2020-12-10
AU2010233791A1 (en) 2011-11-03
KR20200078668A (ko) 2020-07-01
US20120114671A1 (en) 2012-05-10
ES2363358B1 (es) 2012-06-21
CN102574918A (zh) 2012-07-11
WO2010115868A3 (en) 2011-02-03
CY1124148T1 (el) 2022-05-27
CN107964043A (zh) 2018-04-27
KR102373754B1 (ko) 2022-03-15
SG10202010568RA (en) 2020-11-27
KR20220035978A (ko) 2022-03-22
JP2019006784A (ja) 2019-01-17
EP3045474A3 (en) 2016-09-28
KR20120100703A (ko) 2012-09-12
HRP20210352T1 (hr) 2021-05-28
JP2016040255A (ja) 2016-03-24
MX336903B (es) 2016-02-04
US20240400667A1 (en) 2024-12-05
ES2864639T3 (es) 2021-10-14
US10100112B2 (en) 2018-10-16
PT3045474T (pt) 2021-03-22
EP3045474B1 (en) 2021-01-13
JP6207836B2 (ja) 2017-10-04
AU2010233791B2 (en) 2016-01-21
EP3045474A2 (en) 2016-07-20
MX2011010425A (es) 2012-03-06
US20190211095A1 (en) 2019-07-11
SMT202100153T1 (it) 2021-05-07
WO2010115868A2 (en) 2010-10-14
IL215467A (en) 2016-06-30
BRPI1015369A2 (pt) 2021-06-29
JP2012522756A (ja) 2012-09-27
LT3045474T (lt) 2021-05-10
KR20180079470A (ko) 2018-07-10
JP7197665B2 (ja) 2022-12-27
SI3045474T1 (sl) 2021-07-30
HUE054196T2 (hu) 2021-08-30
ES2363358A1 (es) 2011-08-01
JP2022031742A (ja) 2022-02-22
DK3045474T3 (da) 2021-03-22
ZA201107215B (en) 2012-12-27
KR20190093691A (ko) 2019-08-09
CA2757680C (en) 2021-11-02
KR20170121319A (ko) 2017-11-01
JP2020090522A (ja) 2020-06-11
CA2757680A1 (en) 2010-10-14
IL215467A0 (en) 2011-12-29
EP2414394A2 (en) 2012-02-08
US11999782B2 (en) 2024-06-04
PL3045474T3 (pl) 2021-08-09

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