ZA201107215B - Therapeutic agents for the treatment of diseases associated with undersired cell proliferation - Google Patents

Therapeutic agents for the treatment of diseases associated with undersired cell proliferation

Info

Publication number
ZA201107215B
ZA201107215B ZA2011/07215A ZA201107215A ZA201107215B ZA 201107215 B ZA201107215 B ZA 201107215B ZA 2011/07215 A ZA2011/07215 A ZA 2011/07215A ZA 201107215 A ZA201107215 A ZA 201107215A ZA 201107215 B ZA201107215 B ZA 201107215B
Authority
ZA
South Africa
Prior art keywords
undersired
treatment
therapeutic agents
cell proliferation
diseases associated
Prior art date
Application number
ZA2011/07215A
Other languages
English (en)
Inventor
Suarez Joan Seoane
Prieto Silvia Penuelas
Torres Jose Baselga
Original Assignee
Fund Privada Inst Catalana De Recerca I Estudis Avancats (Icrea)
Fund Privada Inst De Recerca Hospital Univ Vall Hebron
Fund Privada Inst D'investigacio Onocologica Vall D'hebron
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fund Privada Inst Catalana De Recerca I Estudis Avancats (Icrea), Fund Privada Inst De Recerca Hospital Univ Vall Hebron, Fund Privada Inst D'investigacio Onocologica Vall D'hebron filed Critical Fund Privada Inst Catalana De Recerca I Estudis Avancats (Icrea)
Publication of ZA201107215B publication Critical patent/ZA201107215B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2093—Leukaemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
ZA2011/07215A 2009-04-03 2011-10-03 Therapeutic agents for the treatment of diseases associated with undersired cell proliferation ZA201107215B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200900928A ES2363358B1 (es) 2009-04-03 2009-04-03 Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable.
PCT/EP2010/054499 WO2010115868A2 (en) 2009-04-03 2010-04-06 Therapeutic agents for the treatment of diseases associated with undesired cell proliferation

Publications (1)

Publication Number Publication Date
ZA201107215B true ZA201107215B (en) 2012-12-27

Family

ID=42342718

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2011/07215A ZA201107215B (en) 2009-04-03 2011-10-03 Therapeutic agents for the treatment of diseases associated with undersired cell proliferation

Country Status (24)

Country Link
US (4) US10100112B2 (cg-RX-API-DMAC7.html)
EP (2) EP2414394A2 (cg-RX-API-DMAC7.html)
JP (5) JP6207836B2 (cg-RX-API-DMAC7.html)
KR (6) KR102373754B1 (cg-RX-API-DMAC7.html)
CN (2) CN107964043A (cg-RX-API-DMAC7.html)
AU (1) AU2010233791B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI1015369A2 (cg-RX-API-DMAC7.html)
CA (1) CA2757680C (cg-RX-API-DMAC7.html)
CY (1) CY1124148T1 (cg-RX-API-DMAC7.html)
DK (1) DK3045474T3 (cg-RX-API-DMAC7.html)
EA (1) EA201101450A1 (cg-RX-API-DMAC7.html)
ES (2) ES2363358B1 (cg-RX-API-DMAC7.html)
HR (1) HRP20210352T1 (cg-RX-API-DMAC7.html)
HU (1) HUE054196T2 (cg-RX-API-DMAC7.html)
IL (1) IL215467A (cg-RX-API-DMAC7.html)
LT (1) LT3045474T (cg-RX-API-DMAC7.html)
MX (1) MX336903B (cg-RX-API-DMAC7.html)
PL (1) PL3045474T3 (cg-RX-API-DMAC7.html)
PT (1) PT3045474T (cg-RX-API-DMAC7.html)
SG (2) SG10202010568RA (cg-RX-API-DMAC7.html)
SI (1) SI3045474T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202100153T1 (cg-RX-API-DMAC7.html)
WO (1) WO2010115868A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201107215B (cg-RX-API-DMAC7.html)

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JP2015071566A (ja) * 2013-10-03 2015-04-16 住友ベークライト株式会社 Ｆｇｆ４遺伝子増幅腫瘍の医薬組成物
IN2014MU00815A (cg-RX-API-DMAC7.html) * 2014-03-11 2015-09-25 Godavari Biorefineries Ltd
CN112494646A (zh) * 2014-06-30 2021-03-16 阿尔托生物科学有限公司 基于il-15的分子及其方法和用途
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EP3067422B1 (en) * 2015-03-13 2024-07-31 Sabanci Üniversitesi Ct-1 inhibitors
AU2016235298B2 (en) 2015-03-23 2021-03-11 Evestra, Inc. Novel cytotoxic agents that preferentially target leukemia inhibitory factor (LIF) for the treatment of malignancies and as new contraceptive agents
EP3173483A1 (en) 2015-11-27 2017-05-31 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Agents for the treatment of diseases associated with undesired cell proliferation
US10583191B2 (en) 2016-12-19 2020-03-10 Mosaic Biomedicals Slu Antibodies against LIF and uses thereof
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AU2019269131B2 (en) * 2018-05-14 2024-02-22 Fundació Privada Institució Catalana De Recerca I Estudis Avançats Antibodies against LIF and dosage forms thereof
EP3807315A2 (en) * 2018-06-18 2021-04-21 MedImmune Limited Methods for improving response to anti-lif antibody treatment in individuals with cancer
CA3103369A1 (en) * 2018-06-18 2019-12-26 Medimmune Limited Combination of lif inhibitors and platinum-based antineoplastic agents for use in treating cancer
WO2020056349A2 (en) * 2018-09-13 2020-03-19 Evestra, Inc. Lif/lifr antagonist oncology and nonmalignant diseases
JP7501876B2 (ja) * 2019-04-17 2024-06-18 国立大学法人広島大学 Ｉｌ－６阻害剤及びｃｃｒ２阻害剤を組み合わせて投与することを特徴とする泌尿器がんの治療剤
CN111020030A (zh) * 2019-12-03 2020-04-17 中山大学 一种骨肉瘤干细胞标志物及其应用、试剂盒
EP3988116A1 (en) * 2020-10-23 2022-04-27 Consejo Superior De Investigaciones Científicas (CSIC) Methods and compositions for the treatment of hematologic malignancies

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Also Published As

Publication number Publication date
KR20220035978A (ko) 2022-03-22
IL215467A0 (en) 2011-12-29
JP2019006784A (ja) 2019-01-17
AU2010233791B2 (en) 2016-01-21
SG10202010568RA (en) 2020-11-27
JP2020090522A (ja) 2020-06-11
KR102373754B1 (ko) 2022-03-15
KR20170121319A (ko) 2017-11-01
JP7197665B2 (ja) 2022-12-27
EP2414394A2 (en) 2012-02-08
CA2757680C (en) 2021-11-02
BRPI1015369A2 (pt) 2021-06-29
EP3045474A3 (en) 2016-09-28
CN102574918A (zh) 2012-07-11
WO2010115868A2 (en) 2010-10-14
KR20200078668A (ko) 2020-07-01
MX336903B (es) 2016-02-04
JP2022031742A (ja) 2022-02-22
US20120114671A1 (en) 2012-05-10
WO2010115868A3 (en) 2011-02-03
SI3045474T1 (sl) 2021-07-30
CY1124148T1 (el) 2022-05-27
US20200385455A1 (en) 2020-12-10
JP2012522756A (ja) 2012-09-27
US11999782B2 (en) 2024-06-04
EP3045474A2 (en) 2016-07-20
JP2016040255A (ja) 2016-03-24
ES2864639T3 (es) 2021-10-14
AU2010233791A1 (en) 2011-11-03
ES2363358B1 (es) 2012-06-21
LT3045474T (lt) 2021-05-10
US20190211095A1 (en) 2019-07-11
PT3045474T (pt) 2021-03-22
CA2757680A1 (en) 2010-10-14
KR20120100703A (ko) 2012-09-12
KR20190093691A (ko) 2019-08-09
JP6207836B2 (ja) 2017-10-04
MX2011010425A (es) 2012-03-06
SG175032A1 (en) 2011-11-28
SMT202100153T1 (it) 2021-05-07
EA201101450A1 (ru) 2012-04-30
HUE054196T2 (hu) 2021-08-30
IL215467A (en) 2016-06-30
US10100112B2 (en) 2018-10-16
US20240400667A1 (en) 2024-12-05
KR20180079470A (ko) 2018-07-10
PL3045474T3 (pl) 2021-08-09
ES2363358A1 (es) 2011-08-01
CN107964043A (zh) 2018-04-27
DK3045474T3 (da) 2021-03-22
HRP20210352T1 (hr) 2021-05-28
EP3045474B1 (en) 2021-01-13

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