SG156683A1 - STIMULATION OF PANCREATIC β CELL PROLIFERATION - Google Patents

STIMULATION OF PANCREATIC β CELL PROLIFERATION

Info

Publication number
SG156683A1
SG156683A1 SG200907103-6A SG2009071036A SG156683A1 SG 156683 A1 SG156683 A1 SG 156683A1 SG 2009071036 A SG2009071036 A SG 2009071036A SG 156683 A1 SG156683 A1 SG 156683A1
Authority
SG
Singapore
Prior art keywords
pancreatic
stimulation
cell proliferation
proliferation
cell
Prior art date
Application number
SG200907103-6A
Other languages
English (en)
Inventor
Markus Stoffel
Pinar Akpinar
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Publication of SG156683A1 publication Critical patent/SG156683A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
SG200907103-6A 2005-06-07 2006-06-07 STIMULATION OF PANCREATIC β CELL PROLIFERATION SG156683A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68785605P 2005-06-07 2005-06-07
US74189305P 2005-12-05 2005-12-05

Publications (1)

Publication Number Publication Date
SG156683A1 true SG156683A1 (en) 2009-11-26

Family

ID=37499109

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200907103-6A SG156683A1 (en) 2005-06-07 2006-06-07 STIMULATION OF PANCREATIC β CELL PROLIFERATION

Country Status (7)

Country Link
US (1) US20100119489A1 (ja)
EP (2) EP2605013A1 (ja)
JP (1) JP2009501002A (ja)
CN (1) CN103173402A (ja)
CA (1) CA2611002A1 (ja)
SG (1) SG156683A1 (ja)
WO (1) WO2006133333A2 (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110286977A1 (en) * 2008-09-30 2011-11-24 Novo Nordisk A/S G6PC2-Encoded Beta Cell Surface Tags
EP2373806A1 (en) * 2008-12-02 2011-10-12 F. Hoffmann-La Roche AG Screening assays for the identification of bace2 inhibitors
WO2010063718A1 (en) * 2008-12-02 2010-06-10 ETH Zürich Screening assay for metabolic disease therapeuticals
MX2012001018A (es) * 2009-08-04 2012-02-21 Hoffmann La Roche Anticuerpo marcador de celula beta.
WO2012113718A1 (en) * 2011-02-21 2012-08-30 Roche Diagnostics Gmbh A diagnostic method for type ii diabetes
SG2014011654A (en) 2011-08-30 2014-08-28 Chdi Foundation Inc Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
AU2012302144B2 (en) 2011-08-30 2017-06-15 Chdi Foundation, Inc. Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
EP2780029A4 (en) * 2011-11-18 2015-06-24 Univ Montreal ORAL LEPTIN FORMULATIONS AND USES THEREOF
CA2955379C (en) 2014-07-17 2022-12-13 Chdi Foundation, Inc. Methods and compositions for treating hiv-related disorders
WO2016099947A1 (en) * 2014-12-19 2016-06-23 Halo Life Science, Llc Use of ellagic acid dihydrate in food products and nutraceuticals
EP3233188A4 (en) * 2014-12-19 2018-11-07 Halo Life Science, LLC Use of ellagic acid dihydrate in pharmaceutical formulations to regulate blood glucose levels
CN110029130A (zh) * 2019-04-24 2019-07-19 皖南医学院第一附属医院(皖南医学院弋矶山医院) 基于CRISPR/Cas9系统在Beta-TC-6细胞株中剔除Sidt2基因方法
US12077758B2 (en) * 2020-05-28 2024-09-03 University Of Massachusetts Oligonucleotides for SARS-CoV-2 modulation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5614492A (en) 1986-05-05 1997-03-25 The General Hospital Corporation Insulinotropic hormone GLP-1 (7-36) and uses thereof
DE69031305T2 (de) 1989-11-03 1998-03-26 Univ Vanderbilt Verfahren zur in vivo-verabreichung von funktionsfähigen fremden genen
US5545618A (en) 1990-01-24 1996-08-13 Buckley; Douglas I. GLP-1 analogs useful for diabetes treatment
US5279833A (en) 1990-04-04 1994-01-18 Yale University Liposomal transfection of nucleic acids into animal cells
DK39892D0 (da) 1992-03-25 1992-03-25 Bernard Thorens Peptid
EP0646178A1 (en) 1992-06-04 1995-04-05 The Regents Of The University Of California expression cassette with regularoty regions functional in the mammmlian host
US5424286A (en) 1993-05-24 1995-06-13 Eng; John Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
US5705483A (en) 1993-12-09 1998-01-06 Eli Lilly And Company Glucagon-like insulinotropic peptides, compositions and methods
US6071890A (en) 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
JP2002510193A (ja) 1997-03-31 2002-04-02 イーライ・リリー・アンド・カンパニー グルカゴン様ペプチド−1類似体
AU2001286171B2 (en) * 2001-05-25 2008-01-10 Serono Genetics Institute S.A. Human CDNAs and proteins and uses thereof
AU2002241277A1 (en) * 2002-03-22 2003-10-08 Incorporated Administrative Agency National Agriculture Organization And Bio-Oriented Research Functional plant, promoter to be used for producing the functional plant and method of using the same
JP2004135546A (ja) * 2002-10-16 2004-05-13 Sumitomo Pharmaceut Co Ltd クローン病の疾患マーカー及びその利用

Also Published As

Publication number Publication date
US20100119489A1 (en) 2010-05-13
CA2611002A1 (en) 2006-12-14
WO2006133333A2 (en) 2006-12-14
EP1896605A4 (en) 2010-09-01
JP2009501002A (ja) 2009-01-15
CN103173402A (zh) 2013-06-26
EP1896605A2 (en) 2008-03-12
EP2605013A1 (en) 2013-06-19
WO2006133333A3 (en) 2009-04-23

Similar Documents

Publication Publication Date Title
SG156683A1 (en) STIMULATION OF PANCREATIC β CELL PROLIFERATION
HUS2100051I1 (hu) Kompozíciók és eljárások sejtproliferációs rendellenességek kezelésére
IN2014CN03629A (ja)
MX2007008137A (es) Triazoloftalazinas como inhibidores de pde2.
HK1115590A1 (en) Triazolophthalazines
SG148142A1 (en) Aryloazol-2-yl cyanoethylamino compunds, method of making and method of using thereof
SG149855A1 (en) N-channel transistor
SG149891A1 (en) Indazole derivatives as inhibitors of hormone-sensitive lipases
TW200640924A (en) VEGF-R2 inhibitors and methods
PT1827441E (pt) Combinações para o tratamento de doenças que envolvem proliferação celular
ME02012B (me) INHIBITORI El AKTIVIRAJUĆIH ENZIMA
SG152239A1 (en) Compounds for proteasome enzyme inhibition
PL1761520T3 (pl) Inhibitory kinazy
TW200700433A (en) Acylated glp-1 compounds
EP1911325A4 (en) IMPLANTABLE MICROPHONE WITH SHAPED CHAMBER
IL176942A0 (en) Imidazolo-5-yl-2-anilinopyrimidines as agents for the inhibition of cell proliferation
SG149831A1 (en) Benzimidazole derivatives
GB2450007A (en) Dynamic update adaptive idle timer
SG145667A1 (en) Chronograph watch
SG142306A1 (en) Methods for neuroprotection
IL189413A0 (en) Inhibitors of cancer cell, t-cell and keratinocyte proliferation
SG149892A1 (en) Identification of novel ige epitopes
SG158857A1 (en) Preparation of ketone amides
HK1130076A1 (en) Method of proliferating lak cell lak
WO2007095256A3 (en) Methods of promoting cardiac cell proliferation