SG155165A1 - Crystalline and amorphous forms of smilagenin - Google Patents
Crystalline and amorphous forms of smilageninInfo
- Publication number
- SG155165A1 SG155165A1 SG200905023-8A SG2009050238A SG155165A1 SG 155165 A1 SG155165 A1 SG 155165A1 SG 2009050238 A SG2009050238 A SG 2009050238A SG 155165 A1 SG155165 A1 SG 155165A1
- Authority
- SG
- Singapore
- Prior art keywords
- smilagenin
- crystalline
- amorphous forms
- hydrated
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0409567.5A GB0409567D0 (en) | 2004-04-28 | 2004-04-28 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SG155165A1 true SG155165A1 (en) | 2009-09-30 |
Family
ID=32408243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG200905023-8A SG155165A1 (en) | 2004-04-28 | 2005-04-28 | Crystalline and amorphous forms of smilagenin |
Country Status (17)
Country | Link |
---|---|
US (2) | US20080004249A1 (ja) |
EP (2) | EP1742960A2 (ja) |
JP (1) | JP2007534736A (ja) |
KR (1) | KR20070028387A (ja) |
CN (2) | CN102516352A (ja) |
AU (1) | AU2005238274A1 (ja) |
BR (1) | BRPI0510458A (ja) |
CA (1) | CA2564368A1 (ja) |
GB (1) | GB0409567D0 (ja) |
IL (1) | IL178870A0 (ja) |
MX (1) | MXPA06012641A (ja) |
NO (1) | NO20065485L (ja) |
RU (1) | RU2006141389A (ja) |
SG (1) | SG155165A1 (ja) |
TW (1) | TW200538145A (ja) |
WO (1) | WO2005105825A2 (ja) |
ZA (1) | ZA200609596B (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20110115589A (ko) | 2009-01-24 | 2011-10-21 | 파이토팜 피엘씨 | 신경영양인자가 매개된 장애의 치료 |
KR20130043197A (ko) | 2010-07-20 | 2013-04-29 | 파이토팜 피엘씨 | 엘-도파, 도파민 효능제 및/또는 도파민 증강제 유도된 장애의 치료 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE632276A (ja) * | 1962-05-15 | |||
US3169959A (en) * | 1963-07-23 | 1965-02-16 | Intermediates Inc | Method of obtaining smilagenin |
CA985172A (en) | 1972-10-06 | 1976-03-09 | Dushan M. Dvornik | Compositions and methods for reducing blood cholesterol |
US4602003A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia |
US4680289A (en) * | 1985-06-05 | 1987-07-14 | Progenics, Inc. | Treatment of obesity and diabetes using sapogenins |
US5017562A (en) | 1987-02-11 | 1991-05-21 | Regents Of The University Of Minnesota | Crystalline saponin-containing complex |
GB9923076D0 (en) | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
EP1719512B1 (en) * | 1998-03-26 | 2011-05-04 | Phytopharm Plc | Sarsasapogenin and smilagenin for treating cognitive dysfunctions |
GB9905275D0 (en) | 1999-03-08 | 1999-04-28 | Phytopharm Ltd | Treatment of conditions associated with membrane-bound receptors and their function |
GB9923078D0 (en) | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
GB9923077D0 (en) | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
GB0000228D0 (en) | 2000-01-06 | 2000-03-01 | Phytopharm Plc | Fluoro substituted sapogenins and their use |
AT409100B (de) | 2000-07-24 | 2002-05-27 | Evg Entwicklung Verwert Ges | Vorrichtung zum schweissen einer drahtgittermatte |
GB0107822D0 (en) | 2001-03-28 | 2001-05-23 | Phytopharm Plc | Sapogenin derivatives their synthesis and use methods based upon their use |
WO2003082893A2 (en) | 2002-03-27 | 2003-10-09 | Phytopharm Plc | Theraputic methods and uses of sapogenins and their derivatives |
BR0315746A (pt) * | 2002-10-28 | 2005-09-06 | Phytopharm Plc | Redução estereospecìfica de sapogen-3-onas |
-
2004
- 2004-04-28 GB GBGB0409567.5A patent/GB0409567D0/en not_active Ceased
-
2005
- 2005-04-28 US US11/587,738 patent/US20080004249A1/en not_active Abandoned
- 2005-04-28 JP JP2007510116A patent/JP2007534736A/ja active Pending
- 2005-04-28 MX MXPA06012641A patent/MXPA06012641A/es unknown
- 2005-04-28 KR KR1020067024949A patent/KR20070028387A/ko not_active Application Discontinuation
- 2005-04-28 EP EP05738225A patent/EP1742960A2/en not_active Withdrawn
- 2005-04-28 RU RU2006141389/04A patent/RU2006141389A/ru not_active Application Discontinuation
- 2005-04-28 TW TW094113668A patent/TW200538145A/zh unknown
- 2005-04-28 SG SG200905023-8A patent/SG155165A1/en unknown
- 2005-04-28 EP EP11155898A patent/EP2402362A2/en not_active Withdrawn
- 2005-04-28 AU AU2005238274A patent/AU2005238274A1/en not_active Abandoned
- 2005-04-28 CN CN2011103029008A patent/CN102516352A/zh active Pending
- 2005-04-28 CA CA002564368A patent/CA2564368A1/en not_active Abandoned
- 2005-04-28 BR BRPI0510458-0A patent/BRPI0510458A/pt not_active IP Right Cessation
- 2005-04-28 WO PCT/GB2005/001635 patent/WO2005105825A2/en active Application Filing
- 2005-04-28 CN CNA2005800133676A patent/CN101076539A/zh active Pending
-
2006
- 2006-10-26 IL IL178870A patent/IL178870A0/en unknown
- 2006-11-17 ZA ZA200609596A patent/ZA200609596B/en unknown
- 2006-11-28 NO NO20065485A patent/NO20065485L/no not_active Application Discontinuation
-
2011
- 2011-02-22 US US13/032,548 patent/US20110144323A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20070028387A (ko) | 2007-03-12 |
NO20065485L (no) | 2007-01-29 |
RU2006141389A (ru) | 2008-06-10 |
MXPA06012641A (es) | 2006-12-15 |
EP2402362A2 (en) | 2012-01-04 |
ZA200609596B (en) | 2008-01-30 |
WO2005105825A3 (en) | 2006-02-23 |
AU2005238274A1 (en) | 2005-11-10 |
US20080004249A1 (en) | 2008-01-03 |
EP1742960A2 (en) | 2007-01-17 |
CN102516352A (zh) | 2012-06-27 |
CN101076539A (zh) | 2007-11-21 |
CA2564368A1 (en) | 2005-11-10 |
JP2007534736A (ja) | 2007-11-29 |
WO2005105825A2 (en) | 2005-11-10 |
US20110144323A1 (en) | 2011-06-16 |
IL178870A0 (en) | 2007-03-08 |
TW200538145A (en) | 2005-12-01 |
GB0409567D0 (en) | 2004-06-02 |
BRPI0510458A (pt) | 2007-10-30 |
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