SG129278A1 - A solid oral dosage form of metformin and glyburide and the method of preparation thereof - Google Patents

A solid oral dosage form of metformin and glyburide and the method of preparation thereof

Info

Publication number
SG129278A1
SG129278A1 SG200401072A SG200401072A SG129278A1 SG 129278 A1 SG129278 A1 SG 129278A1 SG 200401072 A SG200401072 A SG 200401072A SG 200401072 A SG200401072 A SG 200401072A SG 129278 A1 SG129278 A1 SG 129278A1
Authority
SG
Singapore
Prior art keywords
glyburide
solid oral
metformin
oral dosage
preparation
Prior art date
Application number
SG200401072A
Other languages
English (en)
Inventor
Suresh Kumar Gidwani
Purushottam Sharshi Singnurkar
Original Assignee
Usv Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Ltd filed Critical Usv Ltd
Publication of SG129278A1 publication Critical patent/SG129278A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SG200401072A 2003-03-05 2004-03-04 A solid oral dosage form of metformin and glyburide and the method of preparation thereof SG129278A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45198903P 2003-03-05 2003-03-05

Publications (1)

Publication Number Publication Date
SG129278A1 true SG129278A1 (en) 2007-02-26

Family

ID=32094206

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200401072A SG129278A1 (en) 2003-03-05 2004-03-04 A solid oral dosage form of metformin and glyburide and the method of preparation thereof

Country Status (11)

Country Link
US (1) US20040175421A1 (de)
KR (1) KR20040079325A (de)
CN (1) CN1526383A (de)
DE (1) DE102004010921A1 (de)
FR (1) FR2853831A1 (de)
GB (1) GB2399015A (de)
IT (1) ITMI20040428A1 (de)
PL (1) PL365872A1 (de)
SG (1) SG129278A1 (de)
TW (1) TW200505427A (de)
ZA (1) ZA200401748B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ546337A (en) 2003-10-31 2009-03-31 Takeda Pharmaceutical Solid preparation comprising an insulin sensitizer such as pioglitazone hydrochloride, an insulin secretagogue such as glimepiride and a polyoxyethylene sorbitan fatty acid ester such as Polysorbate 80
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
EP2438911A1 (de) * 2010-10-08 2012-04-11 LEK Pharmaceuticals d.d. Pharmazeutische Zusammensetzungen mit Sulfonylharnstoff-Insulinsekretagogum und Polyethylenglykol-Castoröl
US20180008618A1 (en) * 2016-07-08 2018-01-11 Anthony I. Rozmanith Health care

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000040233A1 (de) * 1998-12-30 2000-07-13 Hexal Ag Pharmazeutische zusammensetzung enthaltend metformin, acarbose oder glimepirid und wahlweise poly(dimethyl)siloxan
WO2003026637A2 (en) * 2001-09-28 2003-04-03 Sun Pharmaceutical Industries Limited Dosage form for treatment of diabetes mellitus
WO2004045622A1 (en) * 2002-11-15 2004-06-03 Ranbaxy Laboratories Limited Pharmaceutical dosage forms of biguanide-sulfonylurea combinations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD275399B5 (de) * 1988-09-07 1994-03-31 Dresden Arzneimittel Arzneimitteltechnologisches verfahren zur herstellung einer glibenclamid-arzneiform
US5258185A (en) * 1989-08-23 1993-11-02 Bauer Kurt H Highly active, rapidly absorbable formulations of glibenclamide, processes for the production thereof and their use
IT1276130B1 (it) * 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
EP0974356B1 (de) * 1998-07-15 2003-09-24 Merck Sante Tabletten enthaltend eine Kombination von Glibenclamid und Metformin
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000040233A1 (de) * 1998-12-30 2000-07-13 Hexal Ag Pharmazeutische zusammensetzung enthaltend metformin, acarbose oder glimepirid und wahlweise poly(dimethyl)siloxan
WO2003026637A2 (en) * 2001-09-28 2003-04-03 Sun Pharmaceutical Industries Limited Dosage form for treatment of diabetes mellitus
WO2004045622A1 (en) * 2002-11-15 2004-06-03 Ranbaxy Laboratories Limited Pharmaceutical dosage forms of biguanide-sulfonylurea combinations

Also Published As

Publication number Publication date
US20040175421A1 (en) 2004-09-09
CN1526383A (zh) 2004-09-08
ZA200401748B (en) 2005-09-16
DE102004010921A1 (de) 2004-10-21
ITMI20040428A1 (it) 2004-06-05
KR20040079325A (ko) 2004-09-14
FR2853831A1 (fr) 2004-10-22
TW200505427A (en) 2005-02-16
PL365872A1 (en) 2004-09-06
GB2399015A (en) 2004-09-08
GB0404741D0 (en) 2004-04-07

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