SG11202111693YA - Strains and methods for production of heme-containing proteins - Google Patents
Strains and methods for production of heme-containing proteinsInfo
- Publication number
- SG11202111693YA SG11202111693YA SG11202111693YA SG11202111693YA SG11202111693YA SG 11202111693Y A SG11202111693Y A SG 11202111693YA SG 11202111693Y A SG11202111693Y A SG 11202111693YA SG 11202111693Y A SG11202111693Y A SG 11202111693YA SG 11202111693Y A SG11202111693Y A SG 11202111693YA
- Authority
- SG
- Singapore
- Prior art keywords
- heme
- strains
- production
- methods
- containing proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01037—5-Aminolevulinate synthase (2.3.1.37)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962838770P | 2019-04-25 | 2019-04-25 | |
PCT/US2020/029946 WO2020219972A1 (fr) | 2019-04-25 | 2020-04-24 | Compositions et procédés pour la production de protéines contenant de l'hème |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202111693YA true SG11202111693YA (en) | 2021-11-29 |
Family
ID=70740761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202111693YA SG11202111693YA (en) | 2019-04-25 | 2020-04-24 | Strains and methods for production of heme-containing proteins |
Country Status (12)
Country | Link |
---|---|
US (1) | US11965167B2 (fr) |
EP (1) | EP3959311A1 (fr) |
JP (1) | JP2022531140A (fr) |
KR (1) | KR20220004090A (fr) |
CN (1) | CN114341351A (fr) |
AU (1) | AU2020263580A1 (fr) |
BR (1) | BR112021021154A2 (fr) |
CA (1) | CA3137581A1 (fr) |
IL (1) | IL287418A (fr) |
MX (1) | MX2021012851A (fr) |
SG (1) | SG11202111693YA (fr) |
WO (1) | WO2020219972A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2908463T3 (es) | 2015-05-11 | 2022-04-29 | Impossible Foods Inc | Constructos de expresión y métodos de modificación por ingeniería genética de levaduras metilotróficas |
US10947552B1 (en) | 2020-09-30 | 2021-03-16 | Alpine Roads, Inc. | Recombinant fusion proteins for producing milk proteins in plants |
CA3191387A1 (fr) | 2020-09-30 | 2022-04-07 | Nobell Foods, Inc. | Proteines de lait recombinantes et compositions les comprenant |
CA3231125A1 (fr) | 2021-10-19 | 2023-04-27 | Joshua MARCH | Substitut de viande hybride a base de plante/cellule animale |
US20230193338A1 (en) * | 2021-12-16 | 2023-06-22 | Impossible Foods Inc. | Genetic factor to increase expression of recombinant proteins |
WO2024075085A1 (fr) * | 2022-10-06 | 2024-04-11 | Microo Food Ingredients, S.L. | Compositions dérivées de polymorphes d'ogataea et applications |
CN116790395A (zh) * | 2023-06-28 | 2023-09-22 | 江南大学 | 一种合成高活性血红素类蛋白毕赤酵母底盘菌株的构建及应用 |
Family Cites Families (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3013863A (en) | 1959-01-29 | 1961-12-19 | American Potash & Chem Corp | Method for the preparation of diborane |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
DK162399C (da) | 1986-01-28 | 1992-03-23 | Danisco | Fremgangsmaade til ekspression af gener i baelgplanteceller, dna-fragment, rekombineret dna-fragment samt plasmid til brug ved udoevelsen af fremgangsmaaden |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
US6946587B1 (en) | 1990-01-22 | 2005-09-20 | Dekalb Genetics Corporation | Method for preparing fertile transgenic corn plants |
US5484956A (en) | 1990-01-22 | 1996-01-16 | Dekalb Genetics Corporation | Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin |
US5204253A (en) | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
US5753465A (en) | 1994-08-30 | 1998-05-19 | Carnegie Mellon University | Unmodified recombinant human adult hemoglobin production |
FR2736930B1 (fr) | 1995-07-17 | 1997-09-19 | Biocem | Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines |
US5824511A (en) * | 1995-08-01 | 1998-10-20 | University Technology Corporation | Method for enhancing the production of hemoproteins |
CN1267556C (zh) | 1996-06-10 | 2006-08-02 | 诺沃奇梅兹有限公司 | 提高丝状真菌中血红素蛋白产量的方法 |
JP3794760B2 (ja) | 1996-07-30 | 2006-07-12 | 三井化学株式会社 | フィターゼ生産酵母 |
US5959187A (en) | 1996-09-26 | 1999-09-28 | Bailey; James E. | Expression of oxygen-binding proteins in plants |
JPH10117776A (ja) | 1996-10-22 | 1998-05-12 | Japan Tobacco Inc | インディカイネの形質転換方法 |
US6784340B1 (en) | 1998-01-28 | 2004-08-31 | The Rockefeller University | Chemical inducible promoter used to obtain transgenic plants with a silent marker |
US7803765B2 (en) | 1999-05-05 | 2010-09-28 | Phylogica Limited | Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom |
US7304208B2 (en) | 2000-05-02 | 2007-12-04 | Ventria Bioscience | Expression of human serum albumin (HSA) in monocot seeds |
WO2001098480A2 (fr) | 2000-06-23 | 2001-12-27 | Syngenta Participations Ag | Promoteurs utiles pour reguler l'expression genique des plantes |
US7495148B2 (en) | 2000-07-14 | 2009-02-24 | Unicrop Ltd | Double recoverable block of function |
AU2001292749A1 (en) | 2000-09-18 | 2002-03-26 | Genencor International, Inc. | Twin-arginine translocation in bacillus |
EP1404850B1 (fr) | 2001-07-06 | 2011-10-26 | Monsanto Technology LLC | Compositions et procedes destines a augmenter la segregation de transgenes dans les plantes |
US8021695B2 (en) | 2002-02-15 | 2011-09-20 | Arch Personal Care Products, L.P. | Personal care composition containing leghemoglobin |
AU2002253458A1 (en) | 2002-04-09 | 2003-10-20 | Universitat Basel | Enhancer sequence of the 5-aminolevulinic synthase gene |
US7683238B2 (en) | 2002-11-12 | 2010-03-23 | iBio, Inc. and Fraunhofer USA, Inc. | Production of pharmaceutically active proteins in sprouted seedlings |
US7807870B2 (en) | 2002-12-23 | 2010-10-05 | Max-Planck-Gesellschaft | Method for altering the content of reserve substances in plants |
JP2006522585A (ja) | 2003-04-11 | 2006-10-05 | ベントリア バイオサイエンス | 単子葉植物種子の中で発現させたヒト血中蛋白質 |
US20060041961A1 (en) | 2004-03-25 | 2006-02-23 | Abad Mark S | Genes and uses for pant improvement |
US9068197B2 (en) | 2005-08-24 | 2015-06-30 | The Scripps Research Institute | Translation enhancer-element dependent vector systems |
US20100064384A1 (en) | 2006-04-13 | 2010-03-11 | Max Planck Institut fur molekulare | Method for modifying the atp/adp ratio in cells |
EP2038419A1 (fr) | 2006-07-07 | 2009-03-25 | Bayer BioScience N.V. | Plantes transplastomiques exprimant une protéine ciblée sur le lumen |
JP2008017733A (ja) | 2006-07-11 | 2008-01-31 | Tokyo Univ Of Agriculture | 異種タンパク質の発現方法及び異種タンパク質の発現方法により得られたタンパク質 |
JP2008017774A (ja) | 2006-07-13 | 2008-01-31 | Nipro Corp | ピキア酵母を用いた組換えヒトヘモグロビンの製造 |
CN1974758B (zh) | 2006-12-15 | 2012-03-21 | 湖南省植物保护研究所 | 一种高产5-氨基乙酰丙酸的工程菌的培养方法 |
EP2106447B1 (fr) | 2007-01-26 | 2013-04-17 | Novozymes A/S | Procédé pour l'induction indépendante du méthanol à partir de promoteurs inductibles par le méthanol dans pichia |
WO2009009142A2 (fr) | 2007-07-10 | 2009-01-15 | Monsanto Technology, Llc | Plantes transgéniques à caractéristiques agronomiques améliorées |
EP2058398A1 (fr) | 2007-11-09 | 2009-05-13 | Nipro Corporation | Production d'hémoglobine humaine recombinante à l'aide de levure Pichia |
CN102105589A (zh) | 2008-07-11 | 2011-06-22 | 诺维信公司 | 巴斯德毕赤酵母(Pichia pastoris) DAS启动子变体 |
RU2520748C2 (ru) | 2008-12-04 | 2014-06-27 | Санофи | Способы и применения, включающие гемсвязывающий белок 1 |
US9085766B2 (en) | 2010-05-21 | 2015-07-21 | Cornell University | Methods of producing recombinant heme-binding proteins and uses thereof |
WO2012083424A1 (fr) | 2010-12-21 | 2012-06-28 | The University Of Western Ontario | Nouvelles séquences d'acides aminés de liaison pour immobilisation de ligands |
JP6073138B2 (ja) | 2011-01-27 | 2017-02-01 | 株式会社カネカ | 形質転換用酵母およびタンパク質の製造方法 |
KR102024952B1 (ko) | 2011-07-12 | 2019-09-26 | 임파서블 푸즈 인크. | 소비재를 위한 방법 및 조성물 |
CN102757976B (zh) | 2012-07-12 | 2014-10-08 | 华东理工大学 | 消除甲醇诱导型启动子单一甲醇碳源依赖性的方法 |
CN109289045A (zh) | 2012-09-19 | 2019-02-01 | 国立大学法人大阪大学 | 含有肺炎球菌表面蛋白a的肺炎球菌疫苗 |
RU2769287C2 (ru) | 2013-01-11 | 2022-03-30 | Импоссибл Фудз Инк. | Способы и композиции пригодных к потреблению материалов |
US20160340411A1 (en) | 2013-01-11 | 2016-11-24 | Impossible Foods Inc. | Secretion of heme-containing polypeptides |
GB201309866D0 (en) | 2013-06-03 | 2013-07-17 | Vib Vzw | Means and methods for yield performance in plants |
SI3044320T1 (sl) | 2013-09-11 | 2020-07-31 | Impossible Foods Inc. | Sekrecija polipeptidov, ki vsebujejo hem |
JP6759103B2 (ja) | 2014-03-31 | 2020-09-23 | インポッシブル フーズ インコーポレイテッド | ひき肉レプリカ |
PL3201336T3 (pl) | 2014-10-01 | 2021-12-13 | Impossible Foods Inc. | Sposoby ekstrakcji i oczyszczania białek niezdenaturowanych |
ES2908463T3 (es) | 2015-05-11 | 2022-04-29 | Impossible Foods Inc | Constructos de expresión y métodos de modificación por ingeniería genética de levaduras metilotróficas |
CN105483146B (zh) | 2016-01-22 | 2019-03-26 | 吉林大学 | 一种与致病力相关的灰霉病菌基因BcAls1及其应用 |
US20190292217A1 (en) | 2016-12-02 | 2019-09-26 | Impossible Foods Inc. | Transgenic plants with upregulated heme biosynthesis |
WO2018102656A1 (fr) | 2016-12-02 | 2018-06-07 | City Of Hope | Production de produits recombinés dans des systèmes contenus |
CN108517327B (zh) | 2018-04-20 | 2020-10-30 | 中国科学院天津工业生物技术研究所 | 5-氨基乙酰丙酸高产菌株及其制备方法和应用 |
-
2020
- 2020-04-24 SG SG11202111693YA patent/SG11202111693YA/en unknown
- 2020-04-24 JP JP2021563177A patent/JP2022531140A/ja active Pending
- 2020-04-24 KR KR1020217037341A patent/KR20220004090A/ko unknown
- 2020-04-24 BR BR112021021154A patent/BR112021021154A2/pt unknown
- 2020-04-24 US US16/858,443 patent/US11965167B2/en active Active
- 2020-04-24 CA CA3137581A patent/CA3137581A1/fr active Pending
- 2020-04-24 AU AU2020263580A patent/AU2020263580A1/en active Pending
- 2020-04-24 EP EP20726602.4A patent/EP3959311A1/fr active Pending
- 2020-04-24 WO PCT/US2020/029946 patent/WO2020219972A1/fr unknown
- 2020-04-24 CN CN202080040385.8A patent/CN114341351A/zh active Pending
- 2020-04-24 MX MX2021012851A patent/MX2021012851A/es unknown
-
2021
- 2021-10-20 IL IL287418A patent/IL287418A/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20220004090A (ko) | 2022-01-11 |
US11965167B2 (en) | 2024-04-23 |
CA3137581A1 (fr) | 2020-10-29 |
JP2022531140A (ja) | 2022-07-06 |
IL287418A (en) | 2021-12-01 |
WO2020219972A1 (fr) | 2020-10-29 |
CN114341351A (zh) | 2022-04-12 |
BR112021021154A2 (pt) | 2021-12-14 |
AU2020263580A1 (en) | 2021-11-18 |
US20200340000A1 (en) | 2020-10-29 |
EP3959311A1 (fr) | 2022-03-02 |
MX2021012851A (es) | 2022-02-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL287418A (en) | Varieties and methods of producing proteins containing them | |
EP3517607A4 (fr) | Nouveau mutant d'aspartokinase et procédé de production d'acide l-aminé l'utilisant | |
EP3094718A4 (fr) | Micro-organismes pour la production améliorée d'amino-acides et procédés associés | |
IL287318A (en) | Materials and methods for the production of proteins | |
ZA202203922B (en) | Strains and processes for single cell protein or biomass production | |
EP3663319A4 (fr) | Procédé de préparation d'une nouvelle protéine de fusion et utilisation de protéine de fusion pour améliorer la synthèse de protéines | |
EP4015669A4 (fr) | Acier de canalisation résistant aux hic et résistant aux déformations importantes et son procédé de préparation | |
EP3957646A4 (fr) | Variant de protéine d'exportation de l-thréonine et procédé de production de l-thréonine l'utilisant | |
EP3891175A4 (fr) | Protéines modifiées et méthodes de traitement associées | |
EP3407729A4 (fr) | Biomasse de matière contenant des protéines et procédés de production | |
EP3917943A4 (fr) | Procédés de purification de protéines | |
IL291378A (en) | Methods for filtering condensed matter related to specificity and their uses | |
IL290820A (en) | Methods and constructs for lentiviral vector production | |
EP3585388A4 (fr) | Procédé amélioré de préparation et de purification de bromhydrate de vortioxétine | |
IL290185A (en) | Crystalline forms of risdiplam and their preparation process | |
IL290817A (en) | Methods for producing recombinant human arginase 1 and uses thereof | |
EP3950700A4 (fr) | Complexe peptidique et son procédé de production, et utilisation dudit complexe peptidique | |
EP3998851A4 (fr) | Nouvelles souches de stenotrophomonas et procédés associés | |
EP3980534A4 (fr) | Production de molécules 2-hydroxyacyl-coa et leurs dérivés | |
EP3999547A4 (fr) | Anticorps anti-grp78 et procédé d'utilisation de celui-ci | |
EP3845630A4 (fr) | Variant de trichoderma reesei, et procédé de fabrication de protéine mettant en ?uvre celui-ci | |
GB201903955D0 (en) | Force sensor and method of manufacture | |
EP3631822A4 (fr) | Transformateur mince et son procédé de production | |
GB2585449B (en) | Improved pipe and method of production | |
AU2019904765A0 (en) | Method of producing follistatin and uses thereof |