SG11202108863WA - Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof - Google Patents

Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof

Info

Publication number
SG11202108863WA
SG11202108863WA SG11202108863WA SG11202108863WA SG11202108863WA SG 11202108863W A SG11202108863W A SG 11202108863WA SG 11202108863W A SG11202108863W A SG 11202108863WA SG 11202108863W A SG11202108863W A SG 11202108863WA SG 11202108863W A SG11202108863W A SG 11202108863WA
Authority
SG
Singapore
Prior art keywords
octanylmethanone
diazabicyclo
pyrimidinyl
crystalline
compound
Prior art date
Application number
SG11202108863WA
Other languages
English (en)
Inventor
Xiaojing Yang
Amanda Patrice Surajhie Samuel
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SG11202108863WA publication Critical patent/SG11202108863WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11202108863WA 2019-02-15 2020-02-12 Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof SG11202108863WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962806180P 2019-02-15 2019-02-15
PCT/IB2020/051128 WO2020165788A1 (en) 2019-02-15 2020-02-12 Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof

Publications (1)

Publication Number Publication Date
SG11202108863WA true SG11202108863WA (en) 2021-09-29

Family

ID=69726639

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202108863WA SG11202108863WA (en) 2019-02-15 2020-02-12 Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof

Country Status (13)

Country Link
US (1) US20220144846A1 (es)
EP (1) EP3924355A1 (es)
JP (1) JP2020138960A (es)
KR (1) KR20210114470A (es)
CN (1) CN113646310A (es)
AR (1) AR118099A1 (es)
AU (1) AU2020222083B2 (es)
BR (1) BR112021015951A2 (es)
CA (1) CA3130034C (es)
MX (1) MX2021009761A (es)
SG (1) SG11202108863WA (es)
TW (1) TWI820301B (es)
WO (1) WO2020165788A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021249367A1 (zh) * 2020-06-09 2021-12-16 苏州晶云药物科技股份有限公司 二氮杂双环类化合物的对甲苯磺酸盐新晶型及其制备方法
CN114835717A (zh) * 2021-02-01 2022-08-02 杭州领业医药科技有限公司 Brepocitinib甲苯磺酸盐的晶型及其制备方法和用途
CN113461687B (zh) * 2021-08-10 2022-04-19 四川大学华西医院 2,8-氮杂-[4,5]十螺环酮衍生物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
SI3290421T1 (sl) 2013-02-22 2019-03-29 Pfizer Inc. Kombinacija derivatov pirolo (2,3-D)pirimidina z enim ali več dodatnimi sredstvi za zaviranje z janusom povezane kinaze (JAK)
NO2721710T3 (es) * 2014-08-21 2018-03-31

Also Published As

Publication number Publication date
CN113646310A (zh) 2021-11-12
EP3924355A1 (en) 2021-12-22
TWI820301B (zh) 2023-11-01
WO2020165788A1 (en) 2020-08-20
CA3130034A1 (en) 2020-08-20
KR20210114470A (ko) 2021-09-23
JP2020138960A (ja) 2020-09-03
AU2020222083B2 (en) 2022-11-17
AR118099A1 (es) 2021-09-15
TW202045511A (zh) 2020-12-16
US20220144846A1 (en) 2022-05-12
CA3130034C (en) 2023-12-19
BR112021015951A2 (pt) 2021-10-05
AU2020222083A1 (en) 2021-09-02
MX2021009761A (es) 2021-12-15

Similar Documents

Publication Publication Date Title
IL288816A (en) Aminobenzazepine compounds, immunoconjugates and uses thereof
IL276802A (en) Transduced 2,1-dihydro-3h-pyrazolo[4,3-d]pyrimidin-3-ones
EP3972967A4 (en) HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USES
EP4077311A4 (en) HETEROCYCLIC COMPOUNDS, THEIR PREPARATION PROCESSES AND THEIR USES
IL291033A (en) rip1 inhibitory compounds and methods for their preparation and use
HUE054690T2 (hu) 8-Oxetán-3-il-3,8-diazabiciklo[3.2.1]oktán-3-il-csoporttal szubsztituált vegyületek HIV inhibitorokként
IL285302A (en) Compounds, preparations and methods
EP3774027A4 (en) ELECTRIC CATALYSTS, THEIR PRODUCTION AND USE FOR AMMONIA SYNTHESIS
EP3782998A4 (en) SUBSTITUTED PYRROLOTRIAZINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND THEIR USES
SG11202108863WA (en) Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof
EP3345900A4 (en) 2,4-DI (NITROGENIC GROUP) SUBSTITUTED PYRIMIDINE COMPOUND AND METHOD OF PREPARATION AND USE THEREOF
IL290781A (en) rip1 inhibitory compounds and methods for their preparation and use
EP3743060A4 (en) ANTIBACTERIAL COMPOUNDS, RELATED COMPOSITIONS AND THEIR METHODS OF USE
IL284765A (en) 8,1-naphthyridinone compounds and their uses
EP3846791A4 (en) ILLUDIN ANALOGUES, THEIR USES AND PROCEDURES FOR THEIR SYNTHESIS
IL287120A (en) Compounds, preparations and methods
EP3845538A4 (en) DIHYDROIMIDAZOPYRAZINONE COMPOUND, COMPOSITIONS THEREOF, AND USES THEREOF
EP3793550A4 (en) SUBSTITUTED 2,2' BIPYRIMIDINYL COMPOUNDS, ANALOGS THEREOF AND METHODS THEREOF
ZA202107832B (en) Pyrrole amidopyridone compound, preparation method therefor and use thereof
EP3872065A4 (en) SULFOBIPHENYL COMPOUND, METHOD OF PRODUCTION THEREOF AND USES THEREOF
SG11202008531RA (en) Oxazino-quinazoline and Oxazino-quinoline Type Compound, Preparation Method and Uses Thereof
PL3750893T3 (pl) Związek dioksazoliny, sposób jego wytwarzania oraz jego zastosowania
IL282999A (en) 4,3,1-oxadiazolone compound and drug
EP4007578A4 (en) SUBSTITUTED CYCLOPROPYL-2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGS THEREOF AND METHODS THEREOF
EP3932909A4 (en) BENZOINDAZOLON COMPOUND AND INTERMEDIATE THEREOF