SG11202105267VA - Rna encoding a protein - Google Patents

Rna encoding a protein

Info

Publication number
SG11202105267VA
SG11202105267VA SG11202105267VA SG11202105267VA SG11202105267VA SG 11202105267V A SG11202105267V A SG 11202105267VA SG 11202105267V A SG11202105267V A SG 11202105267VA SG 11202105267V A SG11202105267V A SG 11202105267VA SG 11202105267V A SG11202105267V A SG 11202105267VA
Authority
SG
Singapore
Prior art keywords
protein
rna encoding
rna
encoding
Prior art date
Application number
SG11202105267VA
Other languages
English (en)
Inventor
Justin Selvaraj
Hervé Schaffhauser
Friedrich Metzger
Original Assignee
Versameb Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Versameb Ag filed Critical Versameb Ag
Publication of SG11202105267VA publication Critical patent/SG11202105267VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11202105267VA 2018-12-19 2019-12-18 Rna encoding a protein SG11202105267VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18214221 2018-12-19
EP19208066 2019-11-08
PCT/EP2019/086019 WO2020127532A2 (fr) 2018-12-19 2019-12-18 Arn codant pour une protéine

Publications (1)

Publication Number Publication Date
SG11202105267VA true SG11202105267VA (en) 2021-07-29

Family

ID=68848313

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202105267VA SG11202105267VA (en) 2018-12-19 2019-12-18 Rna encoding a protein

Country Status (18)

Country Link
US (1) US20220002364A1 (fr)
EP (1) EP3898982A2 (fr)
JP (1) JP2022514863A (fr)
KR (1) KR20210105382A (fr)
CN (1) CN113454227A (fr)
AU (1) AU2019407921A1 (fr)
BR (1) BR112021011771A2 (fr)
CA (1) CA3120638A1 (fr)
CL (1) CL2021001571A1 (fr)
CO (1) CO2021007916A2 (fr)
IL (1) IL284035A (fr)
MA (1) MA54503A (fr)
MX (1) MX2021007241A (fr)
PE (1) PE20211342A1 (fr)
PH (1) PH12021551135A1 (fr)
SG (1) SG11202105267VA (fr)
TW (1) TW202043477A (fr)
WO (1) WO2020127532A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021400488A1 (en) 2020-12-14 2023-06-22 Regeneron Pharmaceuticals, Inc. Methods of treating metabolic disorders and cardiovascular disease with inhibin subunit beta e (inhbe) inhibitors
JP2024504414A (ja) * 2021-01-26 2024-01-31 シギロン セラピューティクス, インコーポレイテッド 抗原特異的免疫寛容を誘導するための組成物、デバイス及び方法
WO2022187277A1 (fr) * 2021-03-01 2022-09-09 The Johns Hopkins University Indexation moléculaire de protéines par auto-assemblage (mipsa) pour des recherches protéomiques efficaces
WO2022216944A1 (fr) * 2021-04-07 2022-10-13 Mayo Foundation For Medical Education And Research Procédés et matériaux d'inversion de l'instabilité de la plaque d'athérome
JP2024515184A (ja) * 2021-04-19 2024-04-05 ヴェルサメブ アーゲー 下部尿路症状の治療方法
CN117813380A (zh) * 2021-06-23 2024-04-02 维萨梅布有限公司 用于调节诸基因表达的组合物和方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1604688B1 (fr) 2001-06-05 2010-02-03 CureVac GmbH ARNm stabilisé codant pour un antigène tumoral avec un contenu G/C augmenté
DE102005046490A1 (de) 2005-09-28 2007-03-29 Johannes-Gutenberg-Universität Mainz Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
US20090047259A1 (en) * 2005-12-22 2009-02-19 Enrique Lara Methods of Using the Calcineurin A Variant CnA-beta 1
US9567382B2 (en) * 2008-04-15 2017-02-14 Genzyme Corporation Methods to produce rod-derived cone viability factor (RdCVF)
EP2643468B1 (fr) * 2010-11-22 2018-07-04 Amicus Therapeutics, Inc. Nouvelles séquences signal pour améliorer les expressions de protéines et la sécrétion d'enzymes recombinées et d'autres protéines
DK2797613T3 (da) * 2011-10-27 2020-03-02 Wellstat Ophthalmics Corp Vektorer, der koder for rod-derived cone viability-faktor
WO2014005219A1 (fr) * 2012-07-02 2014-01-09 Iprogen Biotech Inc. Administration intracellulaire de protéines
US10435694B2 (en) * 2014-03-14 2019-10-08 Genentech, Inc. Methods and compositions for secretion of heterologous polypeptides
WO2015162930A1 (fr) * 2014-04-24 2015-10-29 一般社団法人 医療産業イノベーション機構 Procédé permettant d'améliorer l'expression des protéines, et composition pour l'expression des protéines
GB201705484D0 (en) * 2017-04-05 2017-05-17 Quethera Ltd Genetic construct

Also Published As

Publication number Publication date
BR112021011771A2 (pt) 2021-08-31
JP2022514863A (ja) 2022-02-16
AU2019407921A1 (en) 2021-06-10
PH12021551135A1 (en) 2022-02-28
CN113454227A (zh) 2021-09-28
MA54503A (fr) 2021-10-27
CA3120638A1 (fr) 2020-06-25
WO2020127532A3 (fr) 2020-09-17
KR20210105382A (ko) 2021-08-26
CL2021001571A1 (es) 2022-04-18
TW202043477A (zh) 2020-12-01
CO2021007916A2 (es) 2021-09-20
MX2021007241A (es) 2021-09-23
IL284035A (en) 2021-08-31
PE20211342A1 (es) 2021-07-26
US20220002364A1 (en) 2022-01-06
WO2020127532A2 (fr) 2020-06-25
EP3898982A2 (fr) 2021-10-27

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