SG11202101611TA - Controlled-release urethane-elastomers for use in implantable products - Google Patents

Controlled-release urethane-elastomers for use in implantable products

Info

Publication number
SG11202101611TA
SG11202101611TA SG11202101611TA SG11202101611TA SG11202101611TA SG 11202101611T A SG11202101611T A SG 11202101611TA SG 11202101611T A SG11202101611T A SG 11202101611TA SG 11202101611T A SG11202101611T A SG 11202101611TA SG 11202101611T A SG11202101611T A SG 11202101611TA
Authority
SG
Singapore
Prior art keywords
elastomers
controlled
release urethane
implantable products
implantable
Prior art date
Application number
SG11202101611TA
Other languages
English (en)
Inventor
Stephanie Reed
Carissa Smoot
Dennis Shull
Todd Crumbling
John D'ottavio
Peter D Gabriele
Jeremy J Harris
Charles Brendan Nicholson
Jared Ely
Original Assignee
Secant Group Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Secant Group Llc filed Critical Secant Group Llc
Publication of SG11202101611TA publication Critical patent/SG11202101611TA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
    • B29C67/24—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00 characterised by the choice of material
    • B29C67/246—Moulding high reactive monomers or prepolymers, e.g. by reaction injection moulding [RIM], liquid injection moulding [LIM]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
SG11202101611TA 2018-08-21 2019-08-21 Controlled-release urethane-elastomers for use in implantable products SG11202101611TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862720412P 2018-08-21 2018-08-21
US201962872793P 2019-07-11 2019-07-11
PCT/US2019/047533 WO2020041489A1 (fr) 2018-08-21 2019-08-21 Élastomères d'uréthane à libération contrôlée destinés à être utilisés dans des produits implantables

Publications (1)

Publication Number Publication Date
SG11202101611TA true SG11202101611TA (en) 2021-03-30

Family

ID=67902583

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202101611TA SG11202101611TA (en) 2018-08-21 2019-08-21 Controlled-release urethane-elastomers for use in implantable products

Country Status (6)

Country Link
US (3) US10918764B2 (fr)
EP (1) EP3840732A1 (fr)
CN (1) CN112584822A (fr)
CA (1) CA3110222A1 (fr)
SG (1) SG11202101611TA (fr)
WO (1) WO2020041489A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10918764B2 (en) * 2018-08-21 2021-02-16 The Secant Group, Llc Tunable, controlled-release, urethane-containing elastomers and processes of forming the same
JP2023536456A (ja) 2020-07-29 2023-08-25 ザ・セカント・グループ・エルエルシー 架橋ポリ（セバシン酸グリセロール）を含む構造を含む形状誘導型制御放出および保持
CN116670342A (zh) 2020-11-02 2023-08-29 赛康特集团有限责任公司 聚(癸二酸甘油酯)氨基甲酸酯纤维、由其形成的织物及纤维制造方法
US20220211904A1 (en) 2021-01-06 2022-07-07 The Secant Group, Llc Poly(glycerol sebacate) urethane elastomeric leaflet for heart valve replacement
US20230265249A1 (en) * 2022-02-24 2023-08-24 The Secant Group, Llc Urethane-crosslinked polymeric microparticles and processes of manufacturing the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002074406A1 (fr) 2001-03-14 2002-09-26 Penjet Corporation Systemes et procedes d'extraction de gaz dissous dans des liquides
US7722894B2 (en) 2001-10-22 2010-05-25 Massachusetts Institute Of Technology Biodegradable polymer
US20090208540A1 (en) 2003-08-11 2009-08-20 Indevus Pharmaceuticals, Inc. Implantable device for the delivery of naltrexone and methods of use thereof
WO2006029141A1 (fr) * 2004-09-03 2006-03-16 Dow Global Technologies Inc. Isocyanates bloques et utilisation dans des compositions de revetement
AU2007204617A1 (en) 2006-01-12 2007-07-19 Massachusetts Institute Of Technology Biodegradable elastomers
US7923486B2 (en) 2007-10-04 2011-04-12 Board Of Regents, The University Of Texas System Bio-polymer and scaffold-sheet method for tissue engineering
CN101597470B (zh) 2008-06-03 2012-05-23 北京高盟燕山科技有限公司 一种无溶剂型双组分聚氨酯胶粘剂及其制备方法
US10035871B2 (en) * 2011-08-26 2018-07-31 Massachusetts Institute Of Technology Urethane-crosslinked biodegradable elastomers
US9731051B2 (en) 2013-03-26 2017-08-15 Innovia Llc Pacemaker lead and other medical implant devices
CA2950132C (fr) 2014-05-30 2022-01-18 The Secant Group, Llc Preparations de materiaux polymeres a mediation par l'eau
JP6882312B2 (ja) 2016-02-25 2021-06-02 ザ・セカント・グループ・エルエルシー ポリ（グリセロールセバケート）フィラーを含む複合材料
CN106866929A (zh) * 2017-02-24 2017-06-20 中国林业科学研究院林产化学工业研究所 一种多官能度蓖麻油基光固化树脂及其制备方法和应用
US10918764B2 (en) * 2018-08-21 2021-02-16 The Secant Group, Llc Tunable, controlled-release, urethane-containing elastomers and processes of forming the same

Also Published As

Publication number Publication date
US11883557B2 (en) 2024-01-30
EP3840732A1 (fr) 2021-06-30
US20200061240A1 (en) 2020-02-27
US20210138109A1 (en) 2021-05-13
CA3110222A1 (fr) 2020-02-27
US10918764B2 (en) 2021-02-16
US11406732B2 (en) 2022-08-09
WO2020041489A1 (fr) 2020-02-27
US20220257828A1 (en) 2022-08-18
CN112584822A (zh) 2021-03-30

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