SG11202101611TA - Controlled-release urethane-elastomers for use in implantable products - Google Patents

Controlled-release urethane-elastomers for use in implantable products

Info

Publication number
SG11202101611TA
SG11202101611TA SG11202101611TA SG11202101611TA SG11202101611TA SG 11202101611T A SG11202101611T A SG 11202101611TA SG 11202101611T A SG11202101611T A SG 11202101611TA SG 11202101611T A SG11202101611T A SG 11202101611TA SG 11202101611T A SG11202101611T A SG 11202101611TA
Authority
SG
Singapore
Prior art keywords
elastomers
controlled
release urethane
implantable products
implantable
Prior art date
Application number
SG11202101611TA
Inventor
Stephanie Reed
Carissa Smoot
Dennis Shull
Todd Crumbling
John D'ottavio
Peter D Gabriele
Jeremy J Harris
Charles Brendan Nicholson
Jared Ely
Original Assignee
Secant Group Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Secant Group Llc filed Critical Secant Group Llc
Publication of SG11202101611TA publication Critical patent/SG11202101611TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C67/00Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
    • B29C67/24Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00 characterised by the choice of material
    • B29C67/246Moulding high reactive monomers or prepolymers, e.g. by reaction injection moulding [RIM], liquid injection moulding [LIM]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10Processes of additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00Processes of additive manufacturing
SG11202101611TA 2018-08-21 2019-08-21 Controlled-release urethane-elastomers for use in implantable products SG11202101611TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862720412P 2018-08-21 2018-08-21
US201962872793P 2019-07-11 2019-07-11
PCT/US2019/047533 WO2020041489A1 (en) 2018-08-21 2019-08-21 Controlled-release urethane-elastomers for use in implantable products

Publications (1)

Publication Number Publication Date
SG11202101611TA true SG11202101611TA (en) 2021-03-30

Family

ID=67902583

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202101611TA SG11202101611TA (en) 2018-08-21 2019-08-21 Controlled-release urethane-elastomers for use in implantable products

Country Status (6)

Country Link
US (3) US10918764B2 (en)
EP (1) EP3840732A1 (en)
CN (1) CN112584822A (en)
CA (1) CA3110222A1 (en)
SG (1) SG11202101611TA (en)
WO (1) WO2020041489A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202101611TA (en) * 2018-08-21 2021-03-30 Secant Group Llc Controlled-release urethane-elastomers for use in implantable products
EP4188323A1 (en) * 2020-07-29 2023-06-07 The Secant Group, LLC Shape-guided controlled release and retention with structures including crosslinked poly(glycerol sebacate)
WO2022094261A1 (en) 2020-11-02 2022-05-05 The Secant Group, Llc Poly(glycerol sebacate) urethane fibers, fabrics formed therefrom, and methods of fiber manufacture
US20220211904A1 (en) 2021-01-06 2022-07-07 The Secant Group, Llc Poly(glycerol sebacate) urethane elastomeric leaflet for heart valve replacement
WO2023164052A1 (en) * 2022-02-24 2023-08-31 The Secant Group, Llc Urethane-crosslinked poly(glycerol sebacate) microparticles and processes of manufacturing the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6500239B2 (en) 2001-03-14 2002-12-31 Penjet Corporation System and method for removing dissolved gas from a solution
US7722894B2 (en) 2001-10-22 2010-05-25 Massachusetts Institute Of Technology Biodegradable polymer
US20090208540A1 (en) 2003-08-11 2009-08-20 Indevus Pharmaceuticals, Inc. Implantable device for the delivery of naltrexone and methods of use thereof
KR101250703B1 (en) * 2004-09-03 2013-04-03 다우 글로벌 테크놀로지스 엘엘씨 Blocked Isocyanates and Their Use in Coating Compositions
WO2007082305A2 (en) 2006-01-12 2007-07-19 Massachusetts Institute Of Technology Biodegradable elastomers
US7923486B2 (en) 2007-10-04 2011-04-12 Board Of Regents, The University Of Texas System Bio-polymer and scaffold-sheet method for tissue engineering
CN101597470B (en) 2008-06-03 2012-05-23 北京高盟燕山科技有限公司 Solvent free bi-component polyurethane adhesive and preparation method thereof
US10035871B2 (en) * 2011-08-26 2018-07-31 Massachusetts Institute Of Technology Urethane-crosslinked biodegradable elastomers
WO2014160744A1 (en) 2013-03-26 2014-10-02 Innovia Llc Pacemaker lead and other medical implant devices
WO2015184313A1 (en) 2014-05-30 2015-12-03 Secant Medical, Inc. Water-mediated preparations of polymeric materials
CA3015510A1 (en) 2016-02-25 2017-08-31 The Secant Group, Llc Composite containing poly(glycerol sebacate) filler
CN106866929A (en) * 2017-02-24 2017-06-20 中国林业科学研究院林产化学工业研究所 A kind of polyfunctionality castor oil-base light-cured resin and its preparation method and application
SG11202101611TA (en) * 2018-08-21 2021-03-30 Secant Group Llc Controlled-release urethane-elastomers for use in implantable products

Also Published As

Publication number Publication date
WO2020041489A1 (en) 2020-02-27
CA3110222A1 (en) 2020-02-27
US10918764B2 (en) 2021-02-16
EP3840732A1 (en) 2021-06-30
US11883557B2 (en) 2024-01-30
CN112584822A (en) 2021-03-30
US11406732B2 (en) 2022-08-09
US20200061240A1 (en) 2020-02-27
US20210138109A1 (en) 2021-05-13
US20220257828A1 (en) 2022-08-18

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