SG11202101307PA - Aromatic molecules for use in the treatment of pathological conditions - Google Patents
Aromatic molecules for use in the treatment of pathological conditionsInfo
- Publication number
- SG11202101307PA SG11202101307PA SG11202101307PA SG11202101307PA SG11202101307PA SG 11202101307P A SG11202101307P A SG 11202101307PA SG 11202101307P A SG11202101307P A SG 11202101307PA SG 11202101307P A SG11202101307P A SG 11202101307PA SG 11202101307P A SG11202101307P A SG 11202101307PA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- pathological conditions
- aromatic molecules
- molecules
- aromatic
- Prior art date
Links
- 125000003118 aryl group Chemical group 0.000 title 1
- 230000001575 pathological effect Effects 0.000 title 1
Classifications
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- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/21—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing rings other than six-membered aromatic rings
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- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
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- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
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- C07C65/34—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic
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- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/44—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing eight carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
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- Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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EP18190756 | 2018-08-24 | ||
PCT/EP2019/072640 WO2020039092A2 (fr) | 2018-08-24 | 2019-08-23 | Nouvelles molécules aromatiques |
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SG11202101307PA true SG11202101307PA (en) | 2021-03-30 |
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SG11202101307PA SG11202101307PA (en) | 2018-08-24 | 2019-08-23 | Aromatic molecules for use in the treatment of pathological conditions |
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US (1) | US20240140895A1 (fr) |
EP (1) | EP3841095A2 (fr) |
JP (1) | JP2021534212A (fr) |
CN (1) | CN112955439A (fr) |
AU (1) | AU2019326767A1 (fr) |
CA (1) | CA3109421A1 (fr) |
IL (1) | IL280872A (fr) |
MA (1) | MA53431A (fr) |
SG (1) | SG11202101307PA (fr) |
WO (1) | WO2020039092A2 (fr) |
ZA (1) | ZA202100421B (fr) |
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EP3841091A1 (fr) * | 2018-08-24 | 2021-06-30 | Xeniopro GmbH | Éthers phénoxy(hétéro)aryle à activité antiproliférative |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
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US2754286A (en) * | 1951-10-15 | 1956-07-10 | Du Pont | Aldehydes and their acetals |
US3148220A (en) * | 1960-05-31 | 1964-09-08 | Du Pont | 1-aryl-3, 3, 4, 4-tetrafluoro-2, 2-dihalocyclo-butanols and the preparation thereof |
US3113849A (en) * | 1960-06-23 | 1963-12-10 | Dow Chemical Co | Solid gels of liquid hydrocarbons containing salts of alkylphenoxybenzoic acids |
DE2246109A1 (de) * | 1972-09-20 | 1974-03-28 | Bayer Ag | 1-(4-phenoxy-phenyl)-1,3,5-triazinderivate, ein verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
YU163075A (en) * | 1975-07-21 | 1982-05-31 | Science Union & Cie | Process for preparing new phenoxy derivatives |
CN1082023A (zh) * | 1992-05-29 | 1994-02-16 | 山之内制药株式会社 | 含苯甲酸衍生物的医药及新颖的苯甲酸衍生物 |
WO1993024442A1 (fr) * | 1992-05-29 | 1993-12-09 | Yamanouchi Pharmaceutical Co., Ltd. | Medicament renfermant un derive d'acide benzoique, et nouveau derive d'acide benzoique |
JPH0776542A (ja) * | 1993-09-06 | 1995-03-20 | Canon Inc | 液晶性化合物、これを含む液晶組成物、それを有する液晶素子、それらを用いた表示方法および表示装置 |
WO1996010013A1 (fr) * | 1994-09-27 | 1996-04-04 | Ono Pharmaceutical Co., Ltd. | Composes heterocycliques a cinq elements |
AU741382B2 (en) * | 1997-03-26 | 2001-11-29 | Large Scale Biology Corporation | Di-aryl ethers and their derivatives as anti-cancer agents |
CA2425280A1 (fr) * | 2000-10-26 | 2002-05-02 | Pfizer Products Inc. | Inhibiteurs de la pyrimidine-2,4,6-trione metalloproteinase |
WO2003091252A1 (fr) * | 2002-04-25 | 2003-11-06 | Bristol-Myers Squibb Company | Derives d'acide spirobarbiturique utiles en tant qu'inhibiteurs de metalloproteases de matrice (mmp) |
PT2200985E (pt) * | 2007-09-14 | 2011-07-21 | Ortho Mcneil Janssen Pharm | 4-(aril-x-fenil)-1h-piridin-2-onas 1,3-dissubstituídas |
US8153634B2 (en) * | 2008-05-29 | 2012-04-10 | Kowa Company, Ltd. | Carbinol derivatives having cyclic linker |
CN102863345A (zh) * | 2011-07-06 | 2013-01-09 | 中国医学科学院药物研究所 | 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途 |
WO2013134415A1 (fr) * | 2012-03-07 | 2013-09-12 | Vertex Pharmaceuticals Incorporated | Dérivés de mannose pour le traitement d'infections bactériennes |
IN2015DN01035A (fr) * | 2012-07-30 | 2015-06-26 | Taisho Pharmaceutical Co Ltd | |
US20140343118A1 (en) * | 2013-03-14 | 2014-11-20 | Duke University | Methods of treatment using arylcyclopropylamine compounds |
US10919929B2 (en) * | 2013-12-11 | 2021-02-16 | Sloan-Kettering Institute For Cancer Research | Glucocorticoid inhibitors for treatment of prostate cancer |
KR101728443B1 (ko) * | 2013-12-27 | 2017-04-19 | 아구로카네쇼 가부시키가이샤 | 2-아미노니코틴산벤질에스테르 유도체의 제조 방법 |
US11414385B2 (en) * | 2015-12-21 | 2022-08-16 | The University Of Chicago | Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases |
US10772876B2 (en) * | 2016-03-17 | 2020-09-15 | Xeniopro GmbH | Enhancers of Notch signaling and the use thereof in the treatment of cancers and malignancies medicable by upregulation of Notch |
JP2017179158A (ja) * | 2016-03-30 | 2017-10-05 | 出光興産株式会社 | グリース |
WO2018154118A2 (fr) * | 2017-02-24 | 2018-08-30 | Reinmueller Viktoria | Nouveaux composés aromatiques |
CN109111451B (zh) * | 2017-06-26 | 2020-08-11 | 广东东阳光药业有限公司 | 二氢嘧啶类化合物及其在药物中的应用 |
ES2946274T3 (es) * | 2017-10-27 | 2023-07-14 | Boehringer Ingelheim Int | Inhibidores de TRPC6 |
CN108309959A (zh) * | 2018-02-06 | 2018-07-24 | 宁波新靶生物医药科技有限公司 | N或o或c-二芳基取代衍生物的合成及其药学应用 |
CN111868055B (zh) * | 2018-02-16 | 2024-03-08 | 勃林格殷格翰国际有限公司 | Trpc6的抑制剂 |
-
2019
- 2019-08-23 WO PCT/EP2019/072640 patent/WO2020039092A2/fr unknown
- 2019-08-23 CA CA3109421A patent/CA3109421A1/fr active Pending
- 2019-08-23 EP EP19759547.3A patent/EP3841095A2/fr active Pending
- 2019-08-23 SG SG11202101307PA patent/SG11202101307PA/en unknown
- 2019-08-23 CN CN201980069299.7A patent/CN112955439A/zh active Pending
- 2019-08-23 MA MA053431A patent/MA53431A/fr unknown
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2021
- 2021-01-20 ZA ZA2021/00421A patent/ZA202100421B/en unknown
- 2021-02-15 IL IL280872A patent/IL280872A/en unknown
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WO2020039092A2 (fr) | 2020-02-27 |
JP2021534212A (ja) | 2021-12-09 |
WO2020039092A3 (fr) | 2020-04-02 |
US20240140895A1 (en) | 2024-05-02 |
ZA202100421B (en) | 2022-03-30 |
AU2019326767A1 (en) | 2021-02-18 |
IL280872A (en) | 2021-04-29 |
MA53431A (fr) | 2021-06-30 |
CN112955439A (zh) | 2021-06-11 |
CA3109421A1 (fr) | 2020-02-27 |
EP3841095A2 (fr) | 2021-06-30 |
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