SG11202008232QA - Lna-dicarboxylic acid derivatives and process for their preparation - Google Patents
Lna-dicarboxylic acid derivatives and process for their preparationInfo
- Publication number
- SG11202008232QA SG11202008232QA SG11202008232QA SG11202008232QA SG11202008232QA SG 11202008232Q A SG11202008232Q A SG 11202008232QA SG 11202008232Q A SG11202008232Q A SG 11202008232QA SG 11202008232Q A SG11202008232Q A SG 11202008232QA SG 11202008232Q A SG11202008232Q A SG 11202008232QA
- Authority
- SG
- Singapore
- Prior art keywords
- lna
- preparation
- dicarboxylic acid
- acid derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18161687 | 2018-03-14 | ||
| PCT/EP2019/056068 WO2019175126A1 (en) | 2018-03-14 | 2019-03-12 | Lna-dicarboxylic acid derivatives and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202008232QA true SG11202008232QA (en) | 2020-09-29 |
Family
ID=61655630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202008232QA SG11202008232QA (en) | 2018-03-14 | 2019-03-12 | Lna-dicarboxylic acid derivatives and process for their preparation |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20200407392A1 (zh) |
| EP (1) | EP3765473A1 (zh) |
| JP (1) | JP2021516673A (zh) |
| KR (1) | KR20200131232A (zh) |
| CN (1) | CN111836822A (zh) |
| AU (1) | AU2019235331A1 (zh) |
| BR (1) | BR112020014494A2 (zh) |
| CA (1) | CA3092235A1 (zh) |
| IL (1) | IL277066B2 (zh) |
| MX (1) | MX2020009004A (zh) |
| SG (1) | SG11202008232QA (zh) |
| WO (1) | WO2019175126A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018215049A1 (en) | 2017-05-23 | 2018-11-29 | F. Hoffmann-La Roche Ag | Process for galnac oligonucleotide conjugates |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9021625D0 (en) | 1990-10-04 | 1990-11-21 | Ici Plc | Synthesis of oligonucleotides |
| US20040033973A1 (en) * | 2002-08-16 | 2004-02-19 | Muthiah Manoharan | Compounds and oligomeric compounds comprising novel nucleobases |
| EP1692139B1 (en) | 2003-11-13 | 2013-02-13 | Isis Pharmaceuticals, Inc. | 5,6 -dihydroxy-isoindole derivatives as linkers for oligomer solid phase synthesis |
| CN101076546B (zh) * | 2004-09-02 | 2011-10-26 | Isis药物公司 | 用于低聚物合成的聚合珠 |
| US8541569B2 (en) * | 2008-09-06 | 2013-09-24 | Chemgenes Corporation | Phosphoramidites for synthetic RNA in the reverse direction, efficient RNA synthesis and convenient introduction of 3'-end ligands, chromophores and modifications of synthetic RNA |
| IN2014DN06768A (zh) * | 2012-02-17 | 2015-05-22 | Ajinomoto Kk | |
| EP4219516A3 (en) * | 2012-07-13 | 2024-01-10 | Wave Life Sciences Ltd. | Chiral control |
| JP6429264B2 (ja) * | 2013-11-12 | 2018-11-28 | 学校法人東京理科大学 | ボラノホスフェート化合物、及び核酸オリゴマー |
-
2019
- 2019-03-12 AU AU2019235331A patent/AU2019235331A1/en not_active Abandoned
- 2019-03-12 JP JP2020544011A patent/JP2021516673A/ja active Pending
- 2019-03-12 KR KR1020207025494A patent/KR20200131232A/ko not_active Application Discontinuation
- 2019-03-12 WO PCT/EP2019/056068 patent/WO2019175126A1/en unknown
- 2019-03-12 CA CA3092235A patent/CA3092235A1/en active Pending
- 2019-03-12 CN CN201980017513.4A patent/CN111836822A/zh active Pending
- 2019-03-12 SG SG11202008232QA patent/SG11202008232QA/en unknown
- 2019-03-12 MX MX2020009004A patent/MX2020009004A/es unknown
- 2019-03-12 BR BR112020014494-0A patent/BR112020014494A2/pt active Search and Examination
- 2019-03-12 EP EP19709946.8A patent/EP3765473A1/en active Pending
- 2019-03-12 IL IL277066A patent/IL277066B2/en unknown
-
2020
- 2020-09-10 US US17/016,592 patent/US20200407392A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL277066A (en) | 2020-10-29 |
| WO2019175126A1 (en) | 2019-09-19 |
| IL277066B2 (en) | 2023-09-01 |
| IL277066B1 (en) | 2023-05-01 |
| US20200407392A1 (en) | 2020-12-31 |
| KR20200131232A (ko) | 2020-11-23 |
| BR112020014494A2 (pt) | 2020-12-01 |
| MX2020009004A (es) | 2020-10-05 |
| JP2021516673A (ja) | 2021-07-08 |
| CA3092235A1 (en) | 2019-09-19 |
| AU2019235331A1 (en) | 2020-08-06 |
| EP3765473A1 (en) | 2021-01-20 |
| CN111836822A (zh) | 2020-10-27 |
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