SG11202005511VA - Complex comprising a psma-targeting compound linked to a lead or thorium radionuclide - Google Patents
Complex comprising a psma-targeting compound linked to a lead or thorium radionuclideInfo
- Publication number
- SG11202005511VA SG11202005511VA SG11202005511VA SG11202005511VA SG11202005511VA SG 11202005511V A SG11202005511V A SG 11202005511VA SG 11202005511V A SG11202005511V A SG 11202005511VA SG 11202005511V A SG11202005511V A SG 11202005511VA SG 11202005511V A SG11202005511V A SG 11202005511VA
- Authority
- SG
- Singapore
- Prior art keywords
- psma
- complex
- lead
- targeting compound
- compound linked
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
- C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic System without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/24—Lead compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/94—Bismuth compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17206887 | 2017-12-13 | ||
| PCT/EP2018/084738 WO2019115684A1 (fr) | 2017-12-13 | 2018-12-13 | Complexe comprenant un composé ciblant psma lié à un radionucléide tel que le plomb ou le thorium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202005511VA true SG11202005511VA (en) | 2020-07-29 |
Family
ID=60673489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202005511VA SG11202005511VA (en) | 2017-12-13 | 2018-12-13 | Complex comprising a psma-targeting compound linked to a lead or thorium radionuclide |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20200297877A1 (fr) |
| EP (2) | EP3723816A1 (fr) |
| JP (2) | JP7376481B2 (fr) |
| KR (1) | KR20200111169A (fr) |
| CN (2) | CN111491668B (fr) |
| AU (1) | AU2018382539A1 (fr) |
| BR (1) | BR112020011789A2 (fr) |
| CA (1) | CA3085205A1 (fr) |
| IL (2) | IL275317B (fr) |
| MX (1) | MX2020006112A (fr) |
| PH (1) | PH12020550898A1 (fr) |
| SG (1) | SG11202005511VA (fr) |
| UA (1) | UA127532C2 (fr) |
| WO (1) | WO2019115684A1 (fr) |
| ZA (1) | ZA202003877B (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY194484A (en) | 2013-10-18 | 2022-11-30 | Deutsches Krebsforsch | Labeled Inhibitors of Prostate Specific Membrane Antigen (PSMA), Their use as Imaging Agents and Pharmaceutical Agents for the Treatment of Prostate Cancer |
| EP3784294A4 (fr) * | 2018-04-27 | 2022-01-05 | University of Iowa Research Foundation | Compositions pour chélation de métaux à basses températures |
| WO2020061458A1 (fr) * | 2018-09-21 | 2020-03-26 | Endocyte, Inc. | Méthodes de traitement de cancer |
| CN112770785A (zh) * | 2018-09-28 | 2021-05-07 | 海德堡大学 | 前列腺特异性膜抗原(psma)的标记抑制剂，其作为显像剂和药剂用于治疗表达psma的癌症的用途 |
| CN115380117A (zh) * | 2020-02-18 | 2022-11-22 | 恩多塞特公司 | 治疗表达psma的癌症的方法 |
| US20230097381A1 (en) * | 2020-04-24 | 2023-03-30 | Radiomedix, Inc. | Composition, kit and method for diagnosis and treatment of prostate cancer |
| EP4171661A1 (fr) * | 2020-06-29 | 2023-05-03 | Memorial Sloan Kettering Cancer Center | Compositions de dota-haptène pour radioimmunothérapie préciblée à anticorps bispécifique anti-antigène tumoral/anti-dota |
| NL2028075B1 (en) * | 2021-04-26 | 2022-11-03 | Alphathera Ag | Targeting system for cancer comprising a radioisotope |
| CN115745903A (zh) * | 2021-09-03 | 2023-03-07 | 晶核生物医药科技(南京)有限公司 | 一种肽脲素衍生物、含其的药物组合物及其应用 |
| IT202100024335A1 (it) * | 2021-09-22 | 2023-03-22 | Scogif S R L | Complesso radiofarmaceutico per l’imaging e/o per la localizzazione di cellule positive al psma |
| CN114014843B (zh) * | 2021-11-17 | 2022-09-20 | 北京大学第一医院 | 一种psma靶向核素/荧光双模态配体和分子探针与应用 |
| WO2023139203A1 (fr) * | 2022-01-21 | 2023-07-27 | Sciencons AS | Complexes pour le traitement et l'imagerie du cancer |
| WO2023161840A1 (fr) * | 2022-02-24 | 2023-08-31 | Alpha Tau Medical Ltd. | Radiothérapie à diffusion alpha à diffusion améliorée par convection |
| WO2023240135A2 (fr) * | 2022-06-07 | 2023-12-14 | Actinium Pharmaceuticals, Inc. | Chélateurs et conjugués bifonctionnels |
| CN117045828A (zh) * | 2023-10-12 | 2023-11-14 | 北京先通国际医药科技股份有限公司 | 212Pb标记的放射性化合物在制备治疗前列腺癌药物中的用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2007435B1 (fr) | 2006-03-31 | 2019-12-18 | Massachusetts Institute Of Technology | Système pour l'administration ciblée d'agents thérapeutiques |
| US20160095939A1 (en) | 2014-10-07 | 2016-04-07 | Immunomedics, Inc. | Neoadjuvant use of antibody-drug conjugates |
| GB201002508D0 (en) | 2010-02-12 | 2010-03-31 | Algeta As | Product |
| AU2012294639B2 (en) | 2011-08-05 | 2017-10-26 | Molecular Insight Pharmaceuticals, Inc. | Radiolabeled prostate specific membrane antigen inhibitors |
| MY194484A (en) * | 2013-10-18 | 2022-11-30 | Deutsches Krebsforsch | Labeled Inhibitors of Prostate Specific Membrane Antigen (PSMA), Their use as Imaging Agents and Pharmaceutical Agents for the Treatment of Prostate Cancer |
| CN111285918A (zh) * | 2014-05-06 | 2020-06-16 | 约翰霍普金斯大学 | 用于psma靶向的成像和放射疗法的金属/放射性金属标记的psma抑制物 |
| WO2016040179A1 (fr) | 2014-09-08 | 2016-03-17 | Molecular Insight Pharmaceuticals, Inc. | Protection d'organes dans une thérapie radionucléaire ciblant le psma du cancer de la prostate |
| US9433690B1 (en) * | 2015-02-26 | 2016-09-06 | Sciencons AS | Radiopharmaceutical solutions with advantageous properties |
| IL237525A (en) * | 2015-03-03 | 2017-05-29 | Shalom Eli | Method for labeling a prostate-specific membrane antigen with a radioactive isotope |
| PL3433238T3 (pl) * | 2016-03-22 | 2021-12-13 | The Johns Hopkins University | Środki o wysokim powinowactwie ukierunkowane na antygen błonowy specyficzny dla gruczołu krokowego do endoradioterapii raka gruczołu krokowego |
-
2018
- 2018-12-13 BR BR112020011789-7A patent/BR112020011789A2/pt unknown
- 2018-12-13 EP EP18814961.1A patent/EP3723816A1/fr active Pending
- 2018-12-13 IL IL275317A patent/IL275317B/en unknown
- 2018-12-13 MX MX2020006112A patent/MX2020006112A/es unknown
- 2018-12-13 US US16/771,596 patent/US20200297877A1/en not_active Abandoned
- 2018-12-13 EP EP18212268.9A patent/EP3498308A1/fr active Pending
- 2018-12-13 JP JP2020532545A patent/JP7376481B2/ja active Active
- 2018-12-13 CN CN201880081084.2A patent/CN111491668B/zh active Active
- 2018-12-13 CA CA3085205A patent/CA3085205A1/fr active Pending
- 2018-12-13 WO PCT/EP2018/084738 patent/WO2019115684A1/fr unknown
- 2018-12-13 SG SG11202005511VA patent/SG11202005511VA/en unknown
- 2018-12-13 IL IL295190A patent/IL295190A/en unknown
- 2018-12-13 UA UAA202003818A patent/UA127532C2/uk unknown
- 2018-12-13 US US16/219,072 patent/US10377778B2/en active Active
- 2018-12-13 KR KR1020207018503A patent/KR20200111169A/ko not_active Application Discontinuation
- 2018-12-13 CN CN202310010740.2A patent/CN116023429A/zh active Pending
- 2018-12-13 AU AU2018382539A patent/AU2018382539A1/en active Pending
-
2020
- 2020-06-11 PH PH12020550898A patent/PH12020550898A1/en unknown
- 2020-06-25 ZA ZA2020/03877A patent/ZA202003877B/en unknown
-
2023
- 2023-10-26 JP JP2023184091A patent/JP2023178476A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3498308A1 (fr) | 2019-06-19 |
| CA3085205A1 (fr) | 2019-06-20 |
| RU2020120946A (ru) | 2022-01-13 |
| BR112020011789A2 (pt) | 2020-11-24 |
| EP3723816A1 (fr) | 2020-10-21 |
| KR20200111169A (ko) | 2020-09-28 |
| PH12020550898A1 (en) | 2021-03-22 |
| US20190177345A1 (en) | 2019-06-13 |
| MX2020006112A (es) | 2020-08-24 |
| UA127532C2 (uk) | 2023-09-27 |
| IL295190A (en) | 2022-09-01 |
| JP2021506784A (ja) | 2021-02-22 |
| CN116023429A (zh) | 2023-04-28 |
| AU2018382539A1 (en) | 2020-07-02 |
| ZA202003877B (en) | 2021-07-28 |
| CN111491668B (zh) | 2023-01-24 |
| WO2019115684A1 (fr) | 2019-06-20 |
| IL275317A (en) | 2020-07-30 |
| CN111491668A (zh) | 2020-08-04 |
| JP2023178476A (ja) | 2023-12-14 |
| IL275317B (en) | 2022-09-01 |
| JP7376481B2 (ja) | 2023-11-08 |
| US10377778B2 (en) | 2019-08-13 |
| US20200297877A1 (en) | 2020-09-24 |
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