SG11202004765XA - Preparation for magnetic resonance diagnostics for oncological diseases, comprising deuterated 2-amino-2-methylpropionic acid and/or 2-(n-methylamino)-2-methylpropionic acid, and diagnostic method using said preparation - Google Patents
Preparation for magnetic resonance diagnostics for oncological diseases, comprising deuterated 2-amino-2-methylpropionic acid and/or 2-(n-methylamino)-2-methylpropionic acid, and diagnostic method using said preparationInfo
- Publication number
- SG11202004765XA SG11202004765XA SG11202004765XA SG11202004765XA SG11202004765XA SG 11202004765X A SG11202004765X A SG 11202004765XA SG 11202004765X A SG11202004765X A SG 11202004765XA SG 11202004765X A SG11202004765X A SG 11202004765XA SG 11202004765X A SG11202004765X A SG 11202004765XA
- Authority
- SG
- Singapore
- Prior art keywords
- preparation
- methylpropionic acid
- deuterated
- methylamino
- amino
- Prior art date
Links
- FUOOLUPWFVMBKG-UHFFFAOYSA-N 2-Aminoisobutyric acid Chemical class CC(C)(N)C(O)=O FUOOLUPWFVMBKG-UHFFFAOYSA-N 0.000 title 1
- DLAMVQGYEVKIRE-UHFFFAOYSA-N alpha-(methylamino)isobutyric acid Chemical compound CNC(C)(C)C(O)=O DLAMVQGYEVKIRE-UHFFFAOYSA-N 0.000 title 1
- 238000002405 diagnostic procedure Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000000771 oncological effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- High Energy & Nuclear Physics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Signal Processing (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/RU2017/000870 WO2019103636A1 (ru) | 2017-11-21 | 2017-11-21 | Препарат для магнитно-резонансной диагностики онкологических заболеваний, содержащий дейтерированную 2-амино-2-метилпропионовую кислоту и/или 2-(n-метиламино)-2-метилпропионовую кислоту, и способ диагностики с использованием этого препарата |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202004765XA true SG11202004765XA (en) | 2020-06-29 |
Family
ID=66630775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202004765XA SG11202004765XA (en) | 2017-11-21 | 2017-11-21 | Preparation for magnetic resonance diagnostics for oncological diseases, comprising deuterated 2-amino-2-methylpropionic acid and/or 2-(n-methylamino)-2-methylpropionic acid, and diagnostic method using said preparation |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12082918B2 (zh) |
| EP (1) | EP3714783B1 (zh) |
| JP (1) | JP7252653B2 (zh) |
| KR (2) | KR102441674B1 (zh) |
| CN (1) | CN111655145B (zh) |
| AU (1) | AU2017440592B2 (zh) |
| CA (1) | CA3083111C (zh) |
| EA (1) | EA202091298A1 (zh) |
| IL (1) | IL274787B1 (zh) |
| SG (1) | SG11202004765XA (zh) |
| WO (1) | WO2019103636A1 (zh) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4371611A (en) * | 1978-08-07 | 1983-02-01 | W. R. Grace & Co. | Enzymatic diagnostic composition |
| US5042488A (en) | 1987-09-29 | 1991-08-27 | The Washington University | Methods employing deuterium for obtaining direct, observable deuterium magnetic resonance images in vivo and in situ |
| US6574496B1 (en) | 1999-05-19 | 2003-06-03 | Amersham Health As | Magnetic resonance imaging |
| EP1499584B1 (en) * | 2002-04-30 | 2010-08-18 | Emory University | Tumor imaging compounds |
| US20030211036A1 (en) | 2002-05-07 | 2003-11-13 | Hadassa Degani | Method and apparatus for monitoring and quantitatively evaluating tumor perfusion |
| WO2006011810A2 (en) * | 2004-07-30 | 2006-02-02 | Ge Healthcare As | Mr imaging method for the discrimination between healthy and tumour tissue |
| US20070104648A1 (en) * | 2005-11-09 | 2007-05-10 | Glyconix Corporation | Compositions, methods of preparing amino acids, and nuclear magnetic resonance spectroscopy |
| CA2722344A1 (en) * | 2008-04-14 | 2009-10-22 | Emory University | Imaging agents |
| WO2010033511A1 (en) * | 2008-09-16 | 2010-03-25 | Concert Pharmaceuticals, Inc. | Deuterated 2-amino-3-hydroxypropanoic acid derivatives |
| US10646594B2 (en) | 2009-06-19 | 2020-05-12 | Case Western Reserve University | Deuterated metabolic water precursor for detecting and treating diseased tissue |
-
2017
- 2017-11-21 JP JP2020546269A patent/JP7252653B2/ja active Active
- 2017-11-21 KR KR1020207017677A patent/KR102441674B1/ko active IP Right Grant
- 2017-11-21 KR KR1020227012522A patent/KR102522843B1/ko active IP Right Grant
- 2017-11-21 EA EA202091298A patent/EA202091298A1/ru unknown
- 2017-11-21 IL IL274787A patent/IL274787B1/en unknown
- 2017-11-21 AU AU2017440592A patent/AU2017440592B2/en active Active
- 2017-11-21 CA CA3083111A patent/CA3083111C/en active Active
- 2017-11-21 US US16/765,943 patent/US12082918B2/en active Active
- 2017-11-21 SG SG11202004765XA patent/SG11202004765XA/en unknown
- 2017-11-21 WO PCT/RU2017/000870 patent/WO2019103636A1/ru unknown
- 2017-11-21 EP EP17932795.2A patent/EP3714783B1/en active Active
- 2017-11-21 CN CN201780098212.XA patent/CN111655145B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP7252653B2 (ja) | 2023-04-05 |
| KR20200100079A (ko) | 2020-08-25 |
| IL274787A (en) | 2020-07-30 |
| WO2019103636A1 (ru) | 2019-05-31 |
| IL274787B1 (en) | 2024-09-01 |
| EP3714783B1 (en) | 2024-08-14 |
| CA3083111A1 (en) | 2019-05-31 |
| AU2017440592B2 (en) | 2022-06-30 |
| EP3714783A1 (en) | 2020-09-30 |
| EA202091298A1 (ru) | 2020-10-05 |
| KR20220054445A (ko) | 2022-05-02 |
| CN111655145B (zh) | 2023-12-26 |
| US20200352472A1 (en) | 2020-11-12 |
| AU2017440592A1 (en) | 2020-07-02 |
| CA3083111C (en) | 2022-09-20 |
| KR102522843B1 (ko) | 2023-04-18 |
| EP3714783A4 (en) | 2021-05-19 |
| KR102441674B1 (ko) | 2022-09-08 |
| JP2021504472A (ja) | 2021-02-15 |
| CN111655145A (zh) | 2020-09-11 |
| US12082918B2 (en) | 2024-09-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2555890B (en) | System and method for magnetic resonance imaging | |
| EP3216392A4 (en) | Brain disease diagnosis assistance system, brain disease diagnosis assistance method, and program | |
| PL3391041T3 (pl) | Automatyczny kliniczny układ i sposób diagnostyczny | |
| EP3405896A4 (en) | SYSTEMS AND METHODS FOR ENHANCING DIAGNOSIS OF DISEASE | |
| EP3110327A4 (en) | Methods for assessing health conditions using single coil magnetic induction tomography imaging | |
| EP3471608A4 (en) | MAGNETIC RESONANCE SPECTROSCOPY SYSTEM AND METHOD FOR DIAGNOSIS OF PAIN OR INFECTIONS RELATED TO PROPIONIC ACID | |
| PT3527552T (pt) | Derivado fundido tricíclico de -aminoácido, seu método de preparação, e sua utilização médica | |
| EP3324844A4 (en) | System and method for magnetic resonance imaging | |
| EP3295200A4 (en) | Systems and methods for diffusion-weighted multi-spectral magnetic resonance imaging | |
| EP3192886A4 (en) | Device for fixing biological soft tissue, and method for producing same | |
| EP3302262A4 (en) | Head coil and magnetic resonance imaging apparatus employing the same | |
| EP3212080A4 (en) | Magnetic resonance imaging patient temperature monitoring system and related methods | |
| EP3366210A4 (en) | Medical imaging device and magnetic resonance imaging device, and control method therefor | |
| EP3607340A4 (en) | SYSTEM AND METHOD FOR IMPROVED SPINE ECHO-BASED MAGNETIC RESONANCE IMAGING | |
| EP3363466A4 (en) | METHOD FOR PRODUCING CONTRASTING AGENTS FOR MAGNETIC RESONANCE IMAGING | |
| GB2543961B (en) | Magnetic resonance imaging matrix shim coil system and method | |
| EP3402399A4 (en) | MAGNETIC RESONANCE IMAGING APPARATUS AND METHOD THEREFOR | |
| EP3119277A4 (en) | Identifying different types of pain using magnetic resonance spectroscopy | |
| EP3215008A4 (en) | Magnetic resonance imaging apparatus and method | |
| EP3139833A4 (en) | Cardiac phase-resolved non-breath-hold 3-dimensional magnetic resonance angiography | |
| EP3262590A4 (en) | System and method for developing individual and team washroom compliance practices | |
| EP3398511A4 (en) | METHOD, DEVICE AND DEVICE FOR CHEMICAL SHIFT-CODED MAGNETIC RESONANCE IMAGING | |
| EP3679388A4 (en) | PROCESS FOR PERFORMING DIFFUSION-WEIGHTED MAGNETIC RESONANCE MEASUREMENTS | |
| IL255432A0 (en) | A Method for Optimizing the Predetermination of a Time Profile of Contrast Agent Concentration in Diagnostic Imaging Using a Magnetic Resonance System | |
| EP3327733A4 (en) | SUPERCONDUCTING WIRE, SUPER-CHARGE COIL, MRI AND NMR |