PL3391041T3 - Automatyczny kliniczny układ i sposób diagnostyczny - Google Patents

Automatyczny kliniczny układ i sposób diagnostyczny

Info

Publication number
PL3391041T3
PL3391041T3 PL16819054T PL16819054T PL3391041T3 PL 3391041 T3 PL3391041 T3 PL 3391041T3 PL 16819054 T PL16819054 T PL 16819054T PL 16819054 T PL16819054 T PL 16819054T PL 3391041 T3 PL3391041 T3 PL 3391041T3
Authority
PL
Poland
Prior art keywords
diagnostic system
clinical diagnostic
automated clinical
automated
diagnostic
Prior art date
Application number
PL16819054T
Other languages
English (en)
Inventor
Tobias Franz
Uwe Kobold
Peter Kupser
Roland THIELE
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3391041T3 publication Critical patent/PL3391041T3/pl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1885—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
    • G01N30/6039—Construction of the column joining multiple columns in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8804—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 automated systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
PL16819054T 2015-12-18 2016-12-16 Automatyczny kliniczny układ i sposób diagnostyczny PL3391041T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15201395 2015-12-18
PCT/EP2016/081538 WO2017103180A1 (en) 2015-12-18 2016-12-16 Automated clinical diagnostic system and method
EP16819054.4A EP3391041B1 (en) 2015-12-18 2016-12-16 Automated clinical diagnostic system and method

Publications (1)

Publication Number Publication Date
PL3391041T3 true PL3391041T3 (pl) 2020-03-31

Family

ID=55070729

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16819054T PL3391041T3 (pl) 2015-12-18 2016-12-16 Automatyczny kliniczny układ i sposób diagnostyczny

Country Status (8)

Country Link
US (1) US10775355B2 (pl)
EP (2) EP3391041B1 (pl)
JP (2) JP6694509B2 (pl)
KR (1) KR102658086B1 (pl)
CN (1) CN108291896B (pl)
ES (1) ES2761822T3 (pl)
PL (1) PL3391041T3 (pl)
WO (1) WO2017103180A1 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP1500616A2 (en) 2015-12-14 2017-07-28 Pecsi Tudomanyegyetem Data collecting and processing method and arrangement for soft-tomographic examinations
ES2894840T3 (es) 2017-07-04 2022-02-16 Hoffmann La Roche Sistema y procedimiento de diagnóstico clínico automatizado
KR102313468B1 (ko) * 2017-10-19 2021-10-14 티엘 제노믹스 인크. 세포 분류용 칩
EP3594681B1 (en) * 2018-07-10 2024-08-28 Alpha M.O.S. Device for characterising a fluid sample
EP3617701B1 (en) * 2018-08-27 2024-10-23 F. Hoffmann-La Roche AG Sample injector with sample loop and buffer loop
JP6964065B2 (ja) * 2018-12-10 2021-11-10 株式会社日立ハイテク 液体クロマトグラフ質量分析装置
BR112021014045A2 (pt) * 2019-01-17 2021-09-21 F. Hoffmann-La Roche Ag Método para determinar hemoglobina a glicada (hba1c) em uma amostra, kit, uso do kit, sistemas de diagnóstico para determinar hemoglobina a glicada (hba1c) em uma amostra e uso do sistema de diagnóstico
CN113330314A (zh) 2019-01-17 2021-08-31 豪夫迈·罗氏有限公司 用于关于完整蛋白质水平的基于LC-MS的HbA1c测量的自动化样品工作流程
WO2020167649A1 (en) * 2019-02-15 2020-08-20 California Institute Of Technology Tear flow measurement device
US12078620B2 (en) 2019-02-22 2024-09-03 Hitachi High-Tech Corporation Analysis apparatus
EP3748354B1 (en) 2019-06-04 2022-04-06 F. Hoffmann-La Roche AG Quick liquid exchange in liquid chromatography
CN110672864B (zh) * 2019-06-26 2023-05-02 北京华视诺维医疗科技有限公司 临床医疗体液检测质控方法、设备及系统
EP3760292B1 (en) 2019-07-01 2023-04-12 F. Hoffmann-La Roche AG Liquid chromatography systems
JP7402875B2 (ja) * 2019-07-04 2023-12-21 株式会社日立ハイテク 自動分析装置
EP3839499A1 (en) * 2019-12-19 2021-06-23 Roche Diagnostics GmbH Techniques for monitoring an analyzer including multiple liquid chromatography streams
EP3896443B1 (en) 2020-04-15 2024-05-01 F. Hoffmann-La Roche AG Analytical system and method including switching between liquid chromatography fluidic streams
US11994502B2 (en) 2020-06-05 2024-05-28 Snapdragon Chemistry, Inc. Automated online chromatographic sample dilution and preparation system
EP3992627A1 (en) * 2020-10-28 2022-05-04 Roche Diagnostics GmbH Liquid chromatography - stream equivalence by single stream calibration
JP2024500441A (ja) * 2020-12-22 2024-01-09 エフ． ホフマン－ラ ロシュ アーゲー 自動臨床診断システムおよび方法

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364263A (en) * 1980-09-15 1982-12-21 Burroughs Wellcome Co. High pressure liquid chromatographic system
US4835707A (en) * 1986-07-23 1989-05-30 Takeda Chemical Industries, Ltd. Automatic analysis method and apparatus for enzyme reaction
US5800784A (en) * 1996-07-09 1998-09-01 Horn; Marcus J. Chemical sample treatment system and cassette, and methods for effecting multistep treatment process
US6296771B1 (en) * 1999-04-02 2001-10-02 Symyx Technologies, Inc. Parallel high-performance liquid chromatography with serial injection
US6436292B1 (en) * 1999-04-02 2002-08-20 Symyx Technologies, Inc. Parallel high-performance liquid chromatography with post-separation treatment
EP1194200B1 (en) * 1999-04-23 2009-01-07 Advion BioSystems, Inc. High-throughput parallel liquid chromatography system
US20030044846A1 (en) * 2001-04-03 2003-03-06 Gary Eldridge Screening of chemical compounds purified from biological sources
US6881540B2 (en) * 2000-02-23 2005-04-19 Rensselaer Polytechnic Institute High throughtput screening of potential displacer molecules
US6635173B2 (en) 2000-12-28 2003-10-21 Cohesive Technologies, Inc. Multi column chromatography system
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
US7244961B2 (en) * 2002-08-02 2007-07-17 Silicon Valley Scientific Integrated system with modular microfluidic components
WO2004015411A1 (en) * 2002-08-08 2004-02-19 Nanostream, Inc. Systems and methods for high-throughput microfluidic sample analysis
US7132650B1 (en) * 2003-09-26 2006-11-07 Nanostream, Inc. High throughput multi-dimensional sample analysis
US6936167B2 (en) * 2002-10-31 2005-08-30 Nanostream, Inc. System and method for performing multiple parallel chromatographic separations
AU2003287449A1 (en) * 2002-10-31 2004-05-25 Nanostream, Inc. Parallel detection chromatography systems
US6987263B2 (en) * 2002-12-13 2006-01-17 Nanostream, Inc. High throughput systems and methods for parallel sample analysis
US7074327B2 (en) * 2003-05-08 2006-07-11 Nanostream, Inc. Sample preparation for parallel chromatography
US6962658B2 (en) * 2003-05-20 2005-11-08 Eksigent Technologies, Llc Variable flow rate injector
JP4571938B2 (ja) * 2003-06-06 2010-10-27 ウオーターズ・テクノロジーズ・コーポレイシヨン 並列プロセスを実行する装置および方法
CN1773288A (zh) * 2004-11-09 2006-05-17 盛进生物工程(深圳)有限公司 侧流分析系统和方法
US8574432B2 (en) * 2005-04-14 2013-11-05 California Institute Of Technology Integrated chromatography devices and systems for monitoring analytes in real time and methods for manufacturing the same
ES2690319T3 (es) * 2006-06-06 2018-11-20 F. Hoffmann-La Roche Ag Hemólisis diferencial de una muestra de sangre completa
US20080020469A1 (en) * 2006-07-20 2008-01-24 Lawrence Barnes Method for scheduling samples in a combinational clinical analyzer
TW200813430A (en) * 2006-08-01 2008-03-16 Brooks Rand Llc Automated system for detection of chemical compounds
US7815803B2 (en) 2007-06-14 2010-10-19 Roche Diagnostics Operations, Inc. Preparation of samples for LC-MS/MS using magnetic particles
US8133451B2 (en) * 2008-08-28 2012-03-13 Microfluidic Systems, Inc. Sample preparation apparatus
JP5591742B2 (ja) * 2010-06-30 2014-09-17 シスメックス株式会社 検体検査装置の処理能力情報生成装置、検体検査装置、検体検査装置の処理能力情報生成方法、及びコンピュータプログラム
DE202011111053U1 (de) * 2010-10-29 2018-11-21 Thermo Fisher Scientific Oy Automatisiertes System zur Probenaufbereitung und -analyse
EP3570036A1 (en) * 2010-10-29 2019-11-20 Cohesive Technologies Inc. Lc-ms configuration for purification and detection of analytes having a broad range of hydrophobicities
CN203577372U (zh) * 2010-10-29 2014-05-07 赛默菲尼根有限责任公司 模块式多柱色谱盒
US10054569B2 (en) * 2010-10-29 2018-08-21 Thermo Finnigan Llc Method and system for liquid chromatography fluidic monitoring
EP2652513A2 (en) * 2010-12-17 2013-10-23 F.Hoffmann-La Roche Ag Automatically controlling a plurality of devices of a separation and detection process for quantitative sample analysis
EP2834647B1 (en) 2012-04-02 2021-03-03 Siemens Healthcare Diagnostics Inc. Virtual sample queues
CN103308611B (zh) * 2012-09-07 2017-02-22 五行通医疗科技（武汉）有限公司 一种多通道进样的泌尿系结石病因诊断系统及应用方法
US9404900B2 (en) * 2012-12-21 2016-08-02 Thermo Finnigan Llc System for analysis of phase-I and phase-II metabolites and parent compounds without hydrolysis
CN104111341B (zh) * 2013-04-16 2017-10-17 深圳迈瑞生物医疗电子股份有限公司 自动分析装置及其分析方法和分析系统
ES2854880T3 (es) * 2014-06-11 2021-09-23 Hoffmann La Roche Procedimiento y sistema para el análisis de diagnóstico in vitro
US9857339B2 (en) * 2015-01-06 2018-01-02 Waters Technologies Corporation Automated sampling and reaction system for high pressure liquid chromatography and other types of detection

Also Published As

Publication number Publication date
WO2017103180A1 (en) 2017-06-22
EP3391041A1 (en) 2018-10-24
JP2020128990A (ja) 2020-08-27
KR102658086B1 (ko) 2024-04-16
CN108291896B (zh) 2020-11-20
JP6900542B2 (ja) 2021-07-07
ES2761822T3 (es) 2020-05-21
EP3391041B1 (en) 2019-10-16
EP3614138A1 (en) 2020-02-26
US20180292368A1 (en) 2018-10-11
KR20180093944A (ko) 2018-08-22
JP6694509B2 (ja) 2020-05-13
EP3614138B1 (en) 2021-04-21
JP2019505773A (ja) 2019-02-28
US10775355B2 (en) 2020-09-15
CN108291896A (zh) 2018-07-17

Similar Documents

Publication Publication Date Title
PL3391041T3 (pl) Automatyczny kliniczny układ i sposób diagnostyczny
HK1250547A1 (zh) 用於醫療程序規劃的系統和方法
IL259984A (en) System and methods for neurological monitoring and diagnostic assistance
EP3333660A4 (en) ANOMALIE PREDICT TORTIAGNOSIS SYSTEM AND ANOMALY PREDICT DIAGNOSIS PROCEDURE
EP3488248A4 (en) AUTOMATED CLINICAL ANALYSIS SYSTEM AND METHOD
EP3365800A4 (en) AUTOMATIC PATIENT DIAGRAM CHECK SYSTEM AND METHOD
IL260678B (en) Systems and methods to improve diagnosis of diseases
IL250855A0 (en) A system and method for analyzing a motor task
IL253567A0 (en) Method and system for automatic vision testing
EP3317428A4 (en) Method and system for diagnostic testing
EP3001196B8 (en) Blood testing system and method
IL247540A0 (en) System and method for endoscopic measurement
SG11201706341RA (en) Systems and methods for biological analysis
EP3333661A4 (en) ANOMALIE PREDICT TORTIAGNOSIS SYSTEM AND ANOMALY PREDICT DIAGNOSIS PROCEDURE
EP3299918A4 (en) Abnormality diagnosis system and abnormality diagnosis method
EP3229093A4 (en) Abnormality diagnosis method and abnormality diagnosis system
HK1252032A1 (zh) 測試系統和測試方法
ZA201800288B (en) System and method for tokenization
TWI559897B (en) System and method for measuring physiological parameters
EP3383473A4 (en) SYSTEM AND METHOD FOR BLOOD TESTING
EP3259600C0 (en) DIAGNOSTIC ASSAY AND TREATMENT OF PREECLAMPSIA
IL251134B (en) A system and method for monitoring and managing laboratory procedures
HK1214649A1 (zh) 體外診斷分析方法和系統
EP3282938C0 (en) SYSTEMS AND METHODS FOR PERFORMING AN ELECTROCARDIOGRAM
SG11201700087UA (en) On-site diagnostic system and the method thereof