SG11202002528SA - Radioactive drug - Google Patents

Radioactive drug

Info

Publication number
SG11202002528SA
SG11202002528SA SG11202002528SA SG11202002528SA SG11202002528SA SG 11202002528S A SG11202002528S A SG 11202002528SA SG 11202002528S A SG11202002528S A SG 11202002528SA SG 11202002528S A SG11202002528S A SG 11202002528SA SG 11202002528S A SG11202002528S A SG 11202002528SA
Authority
SG
Singapore
Prior art keywords
radioactive drug
radioactive
drug
Prior art date
Application number
SG11202002528SA
Other languages
English (en)
Inventor
Yasushi Arano
Tomoya Uehara
Hiroyuki Suzuki
Original Assignee
Univ Chiba Nat Univ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Chiba Nat Univ Corp filed Critical Univ Chiba Nat Univ Corp
Publication of SG11202002528SA publication Critical patent/SG11202002528SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
SG11202002528SA 2017-09-26 2018-09-26 Radioactive drug SG11202002528SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017185484 2017-09-26
PCT/JP2018/035786 WO2019065774A1 (ja) 2017-09-26 2018-09-26 放射性薬剤

Publications (1)

Publication Number Publication Date
SG11202002528SA true SG11202002528SA (en) 2020-04-29

Family

ID=65903027

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002528SA SG11202002528SA (en) 2017-09-26 2018-09-26 Radioactive drug

Country Status (8)

Country Link
US (1) US11167050B2 (ja)
EP (1) EP3689892B1 (ja)
JP (1) JP7207740B2 (ja)
KR (1) KR20200056979A (ja)
CN (1) CN111065646B (ja)
CA (1) CA3086454A1 (ja)
SG (1) SG11202002528SA (ja)
WO (1) WO2019065774A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3043816A1 (en) 2016-11-18 2018-05-24 Astellas Pharma Inc. Novel anti-human muc1 antibody fab fragment
TWI795415B (zh) 2017-07-07 2023-03-11 日商安斯泰來製藥股份有限公司 新穎的抗人類CEACAM5抗體Fab片段
CA3097101A1 (en) * 2018-04-16 2019-10-24 Nihon Medi-Physics Co., Ltd. Modified antibody and radioactive metal-labelled antibody
TWI835880B (zh) 2018-10-10 2024-03-21 日商安斯泰來製藥股份有限公司 含有標識部-抗人類抗體Fab片段複合體之醫藥組成物
US11919972B2 (en) 2018-11-02 2024-03-05 Regeneron Pharmaceuticals, Inc. Peptide libraries with non-canonical amino acids
JPWO2020145228A1 (ja) 2019-01-07 2021-11-11 アステラス製薬株式会社 配位子及びCEACAM5抗体Fabフラグメントからなる複合体
AU2021230210A1 (en) 2020-03-04 2022-09-22 Kyoto University Compound and radioactive labeling compound
WO2022098745A1 (en) * 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, delivery systems, and methods useful in tumor therapy
US20240174622A1 (en) 2021-03-04 2024-05-30 Nihon Medi-Physics Co., Ltd. Compound and radioactive labeling compound
CN118382464A (zh) 2021-11-30 2024-07-23 日本医事物理股份有限公司 稳定化放射性药物组合物
CN114685389B (zh) * 2022-03-04 2023-10-27 复旦大学附属中山医院 一种基于迈克尔加成的pet显像剂、制备方法与用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005047821A (ja) * 2003-07-30 2005-02-24 Nihon Medi Physics Co Ltd シクロペンタジエニルカルボニル基を含む放射性化合物を用いた診断及び治療用薬剤
WO2013081091A1 (ja) 2011-12-01 2013-06-06 国立大学法人 千葉大学 非特異的腎集積が低減された放射性標識ポリペプチド作製用薬剤
JP6410339B2 (ja) * 2013-03-25 2018-10-24 国立大学法人千葉大学 放射性核種標識オクトレオチド誘導体
CN108699108B (zh) 2016-03-01 2022-04-08 国立大学法人千叶大学 放射性标记药物

Also Published As

Publication number Publication date
US20200268913A1 (en) 2020-08-27
JP7207740B2 (ja) 2023-01-18
CN111065646A (zh) 2020-04-24
WO2019065774A1 (ja) 2019-04-04
JPWO2019065774A1 (ja) 2021-01-28
CA3086454A1 (en) 2019-04-04
CN111065646B (zh) 2023-05-30
US11167050B2 (en) 2021-11-09
EP3689892A1 (en) 2020-08-05
EP3689892B1 (en) 2024-07-17
EP3689892A4 (en) 2021-05-12
KR20200056979A (ko) 2020-05-25

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