SG11202001931WA - Combination therapies of hepatitis b virus (hbv)-infected individuals using parapoxvirus ovis (ppvo) and at least one further antiviral drug - Google Patents
Combination therapies of hepatitis b virus (hbv)-infected individuals using parapoxvirus ovis (ppvo) and at least one further antiviral drugInfo
- Publication number
- SG11202001931WA SG11202001931WA SG11202001931WA SG11202001931WA SG11202001931WA SG 11202001931W A SG11202001931W A SG 11202001931WA SG 11202001931W A SG11202001931W A SG 11202001931WA SG 11202001931W A SG11202001931W A SG 11202001931WA SG 11202001931W A SG11202001931W A SG 11202001931WA
- Authority
- SG
- Singapore
- Prior art keywords
- ppvo
- hbv
- hepatitis
- virus
- combination therapies
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24211—Parapoxvirus, e.g. Orf virus
- C12N2710/24232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24211—Parapoxvirus, e.g. Orf virus
- C12N2710/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17189890 | 2017-09-07 | ||
| EP17196684 | 2017-10-16 | ||
| PCT/EP2018/074202 WO2019048640A1 (en) | 2017-09-07 | 2018-09-07 | POLYTHERAPIES FOR INDIVIDUALS WITH HEPATITIS B (HBV) VIRUS INFECTION USING PARAPOXVIRUS OVIS (PPVO) AND AT LEAST ONE OTHER ANTIVIRAL MEDICINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202001931WA true SG11202001931WA (en) | 2020-04-29 |
Family
ID=63442656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202001931WA SG11202001931WA (en) | 2017-09-07 | 2018-09-07 | Combination therapies of hepatitis b virus (hbv)-infected individuals using parapoxvirus ovis (ppvo) and at least one further antiviral drug |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20200261520A1 (ko) |
| EP (1) | EP3678697A1 (ko) |
| JP (2) | JP2020533314A (ko) |
| KR (1) | KR20200051685A (ko) |
| CN (1) | CN111093697A (ko) |
| AU (1) | AU2018327688B2 (ko) |
| BR (1) | BR112020004539A2 (ko) |
| CA (1) | CA3075206A1 (ko) |
| CL (1) | CL2020000556A1 (ko) |
| CU (1) | CU20200016A7 (ko) |
| EC (1) | ECSP20016672A (ko) |
| GE (1) | GEP20237518B (ko) |
| IL (1) | IL273093A (ko) |
| MA (1) | MA50071A (ko) |
| MX (1) | MX2020002605A (ko) |
| PH (1) | PH12020500445A1 (ko) |
| SG (1) | SG11202001931WA (ko) |
| TW (1) | TW201919675A (ko) |
| UY (1) | UY37869A (ko) |
| WO (1) | WO2019048640A1 (ko) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3906929A1 (en) | 2020-05-08 | 2021-11-10 | AiCuris GmbH & Co. KG | Letermovir for use in the prevention and the treatment of coronavirus infections |
| PT3906970T (pt) * | 2020-05-08 | 2022-08-23 | Aicuris Gmbh & Co Kg | Parapoxvírus para condicionamento e tratamento de infeções por coronavírus |
| WO2021242850A1 (en) * | 2020-05-28 | 2021-12-02 | The Regents Of The University Of Michigan | Compositions and methods for preventing and treating sars-cov-2 infection |
| WO2023083950A1 (en) | 2021-11-10 | 2023-05-19 | Aicuris Gmbh & Co. Kg | Parapoxvirus for preparing for and treatment of respiratory virus infections in combination with immunomodulators |
| WO2023083943A1 (en) | 2021-11-10 | 2023-05-19 | Aicuris Gmbh & Co. Kg | Parapoxvirus for preparing for and treatment of respiratory virus infections in combination with antivirals |
| WO2023083951A1 (en) | 2021-11-10 | 2023-05-19 | Aicuris Gmbh & Co. Kg | Parapoxvirus for preparing for and treatment of respiratory syncytial virus infections |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ523535A (en) * | 2000-07-11 | 2004-12-24 | Bayer Ag | Use of strains of the Parapoxvirus ovis against organ fibroses |
| SI21122A (sl) * | 2000-07-11 | 2003-08-31 | Bayer Aktiengesellschaft | Uporaba sevov parapoksvirusa ovis za proizvodnjo antivirusnih zdravil in zdravil proti raku |
| JP4897677B2 (ja) * | 2004-07-13 | 2012-03-14 | アイキュリス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コムパニー・コマンディットゲゼルシャフト | Ｈｉｖ／ａｉｄｓの処置用の他の抗ウイルス剤と組み合わせたパラポックスウイルス |
| EP1962841A1 (en) * | 2005-12-15 | 2008-09-03 | Bayer HealthCare AG | Diaryl urea for treating virus infections |
| JP5699093B2 (ja) * | 2012-01-05 | 2015-04-08 | アイキュリス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コムパニー・コマンディットゲゼルシャフトＡｉＣｕｒｉｓ ＧｍｂＨ ＆ Ｃｏ． ＫＧ | パラポックスウイルス・オヴィスの組換えタンパク質およびそれ由来の医薬組成物 |
| WO2017015451A1 (en) * | 2015-07-22 | 2017-01-26 | Enanta Pharmaceuticals, Inc. | Hepatitis b antiviral agents |
-
2018
- 2018-09-06 TW TW107131294A patent/TW201919675A/zh unknown
- 2018-09-07 GE GEAP201815308A patent/GEP20237518B/en unknown
- 2018-09-07 JP JP2020513816A patent/JP2020533314A/ja active Pending
- 2018-09-07 KR KR1020207009442A patent/KR20200051685A/ko not_active Application Discontinuation
- 2018-09-07 EP EP18762338.4A patent/EP3678697A1/en not_active Withdrawn
- 2018-09-07 CN CN201880058406.1A patent/CN111093697A/zh active Pending
- 2018-09-07 MX MX2020002605A patent/MX2020002605A/es unknown
- 2018-09-07 US US16/645,020 patent/US20200261520A1/en not_active Abandoned
- 2018-09-07 CA CA3075206A patent/CA3075206A1/en active Pending
- 2018-09-07 CU CU2020000016A patent/CU20200016A7/es unknown
- 2018-09-07 SG SG11202001931WA patent/SG11202001931WA/en unknown
- 2018-09-07 UY UY0001037869A patent/UY37869A/es not_active Application Discontinuation
- 2018-09-07 BR BR112020004539-0A patent/BR112020004539A2/pt active Search and Examination
- 2018-09-07 WO PCT/EP2018/074202 patent/WO2019048640A1/en unknown
- 2018-09-07 MA MA050071A patent/MA50071A/fr unknown
- 2018-09-07 AU AU2018327688A patent/AU2018327688B2/en active Active
-
2020
- 2020-03-05 IL IL273093A patent/IL273093A/en unknown
- 2020-03-05 PH PH12020500445A patent/PH12020500445A1/en unknown
- 2020-03-05 CL CL2020000556A patent/CL2020000556A1/es unknown
- 2020-03-06 EC ECSENADI202016672A patent/ECSP20016672A/es unknown
-
2022
- 2022-08-02 JP JP2022123132A patent/JP2022167901A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3075206A1 (en) | 2019-03-14 |
| PH12020500445A1 (en) | 2020-11-09 |
| MX2020002605A (es) | 2020-07-20 |
| EP3678697A1 (en) | 2020-07-15 |
| CL2020000556A1 (es) | 2020-09-04 |
| CN111093697A (zh) | 2020-05-01 |
| JP2020533314A (ja) | 2020-11-19 |
| CU20200016A7 (es) | 2020-11-30 |
| JP2022167901A (ja) | 2022-11-04 |
| ECSP20016672A (es) | 2020-06-30 |
| IL273093A (en) | 2020-04-30 |
| AU2018327688A1 (en) | 2020-03-19 |
| MA50071A (fr) | 2020-07-15 |
| UY37869A (es) | 2019-04-30 |
| AU2018327688B2 (en) | 2022-12-01 |
| WO2019048640A1 (en) | 2019-03-14 |
| TW201919675A (zh) | 2019-06-01 |
| US20200261520A1 (en) | 2020-08-20 |
| BR112020004539A2 (pt) | 2020-09-08 |
| GEP20237518B (en) | 2023-07-10 |
| KR20200051685A (ko) | 2020-05-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL273093A (en) | Combination of drugs for the treatment of hepatitis B virus type HBV patients using Parafoxvirus Obis (PPVO) and at least one other antiviral agent | |
| ZA201806651B (en) | Elimination of hepatitis b virus with antiviral agents | |
| HK1251220A1 (zh) | 用於治療和預防乙型肝炎病毒感染的新的四環4-氧代-吡啶-3-甲酸衍生物 | |
| HK1255463A1 (zh) | Hbv衣殼組裝抑制劑和干擾素的組合療法 | |
| HK1214509A1 (zh) | 穏定的人類免疫缺陷病毒 包膜蛋白基因 三聚體疫苗及其使用方法 | |
| IL275427A (en) | Hepatitis virus vaccines HBV) B) and their uses | |
| IL249660A0 (en) | Methods for treating hepatitis b virus and hepatitis d virus infections | |
| HK1251010A1 (zh) | 用於治療乙型肝炎病毒(hbv)感染的試劑及用途 | |
| LT3416675T (lt) | Hepatito delta viruso infekcijos gydymas interferonu lambda | |
| IL275429A (en) | Methods and device for administering hepatitis virus HBV vaccines) B) | |
| HK1249914A1 (zh) | 能夠在人脂肪衍生的幹細胞和肝細胞中抑制丙肝病毒複製的肽及其衍生物 | |
| EP3359577A4 (en) | HEPATITIS C VIRUS E1 / E2 HETERODIMERS AND METHODS OF PRODUCING THE SAME | |
| EP3463469C0 (en) | COMBINATION OF LEDIPASVIR AND SOFOSBUVIR FOR USE IN THE TREATMENT OF HEPATITIS B IN HUMAN | |
| HK1259329A1 (zh) | 包含乙型肝炎病毒的表面抗原和核衣殼抗原的藥用組合物 | |
| EP3452595A4 (en) | REAGENTS FOR THE TREATMENT OF HEPATITIS B VIRUS (HBV) INFECTION AND USE THEREOF | |
| ZA202104076B (en) | Hepatitis b virus vaccine and uses thereof | |
| IL286484B (en) | Reagents for treatment of hepatitis b virus (hbv) infection and use thereof | |
| EA202090597A1 (ru) | Комбинированная терапия пациентов, инфицированных вирусом гепатита в (hbv), с использованием parapoxvirus ovis (ppvo) и по меньшей мере одного дополнительного противовирусного средства | |
| AU2015901617A0 (en) | Reagents for treatment of hepatitis B virus (HBV) infection and use thereof |