SG11202001497PA - Continuous diafiltration by means of tank cycling - Google Patents
Continuous diafiltration by means of tank cyclingInfo
- Publication number
- SG11202001497PA SG11202001497PA SG11202001497PA SG11202001497PA SG11202001497PA SG 11202001497P A SG11202001497P A SG 11202001497PA SG 11202001497P A SG11202001497P A SG 11202001497PA SG 11202001497P A SG11202001497P A SG 11202001497PA SG 11202001497P A SG11202001497P A SG 11202001497PA
- Authority
- SG
- Singapore
- Prior art keywords
- continuous diafiltration
- cycling
- tank
- tank cycling
- diafiltration
- Prior art date
Links
- 238000011035 continuous diafiltration Methods 0.000 title 1
- 230000001351 cycling effect Effects 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/22—Controlling or regulating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/149—Multistep processes comprising different kinds of membrane processes selected from ultrafiltration or microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
- B01D65/02—Membrane cleaning or sterilisation ; Membrane regeneration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/04—Specific process operations in the feed stream; Feed pretreatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/08—Specific process operations in the concentrate stream
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/12—Addition of chemical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/25—Recirculation, recycling or bypass, e.g. recirculation of concentrate into the feed
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/25—Recirculation, recycling or bypass, e.g. recirculation of concentrate into the feed
- B01D2311/252—Recirculation of concentrate
- B01D2311/2523—Recirculation of concentrate to feed side
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/18—Specific valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/24—Specific pressurizing or depressurizing means
- B01D2313/243—Pumps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/48—Mechanisms for switching between regular separation operations and washing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/50—Specific extra tanks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/50—Specific extra tanks
- B01D2313/502—Concentrate storage tanks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/60—Specific sensors or sensor arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
- B01D2315/10—Cross-flow filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
- B01D2315/14—Batch-systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
- B01D2315/16—Diafiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2317/00—Membrane module arrangements within a plant or an apparatus
- B01D2317/02—Elements in series
- B01D2317/022—Reject series
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2317/00—Membrane module arrangements within a plant or an apparatus
- B01D2317/04—Elements in parallel
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/04—Backflushing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/16—Use of chemical agents
- B01D2321/168—Use of other chemical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/40—Automatic control of cleaning processes
Landscapes
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762585132P | 2017-11-13 | 2017-11-13 | |
| PCT/US2018/058660 WO2019094249A1 (en) | 2017-11-13 | 2018-11-01 | Continuous diafiltration by means of tank cycling |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202001497PA true SG11202001497PA (en) | 2020-03-30 |
Family
ID=64362696
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202001497PA SG11202001497PA (en) | 2017-11-13 | 2018-11-01 | Continuous diafiltration by means of tank cycling |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11691107B2 (https=) |
| EP (1) | EP3710141B1 (https=) |
| JP (1) | JP7177154B2 (https=) |
| KR (2) | KR20220050232A (https=) |
| CN (1) | CN111246930B (https=) |
| CA (1) | CA3080724C (https=) |
| ES (1) | ES2995480T3 (https=) |
| SG (1) | SG11202001497PA (https=) |
| TW (2) | TWI753216B (https=) |
| WO (1) | WO2019094249A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111246930B (zh) | 2017-11-13 | 2022-12-02 | Emd密理博公司 | 通过罐循环的连续透滤 |
| ES3064507T3 (en) * | 2018-08-07 | 2026-04-27 | Merz Pharma Gmbh & Co Kgaa | Method for dynamic filtration of a cross-linked hydrogel |
| US11241656B2 (en) * | 2018-11-29 | 2022-02-08 | Watersep Bioseparations Llc | Single pass cross flow diafiltration module and method |
| EP3939691B1 (en) * | 2020-07-13 | 2023-11-22 | Sartorius Stedim Biotech GmbH | Device assembly for producing bioconjugates |
| EP4182427A1 (en) * | 2020-07-15 | 2023-05-24 | Global Life Sciences Solutions USA LLC | Bioprocessing perfusion system having a plurality of filters and method of operating the same |
| CN116406369A (zh) * | 2020-10-05 | 2023-07-07 | 百时美施贵宝公司 | 用于浓缩蛋白质的方法 |
| WO2022251261A1 (en) * | 2021-05-25 | 2022-12-01 | Boehringer Ingelheim International Gmbh | A method and system for integrated and continuous viral filtration, concentration and buffer exchange |
| WO2023183269A1 (en) * | 2022-03-21 | 2023-09-28 | Repligen Corporation | Variable pathlength uv spectroscopy based automated tff system |
| WO2023230492A1 (en) * | 2022-05-26 | 2023-11-30 | Eli Lilly And Company | Continuous tangential flow filtration system |
| WO2024138152A1 (en) * | 2022-12-23 | 2024-06-27 | Asahi Kasei Bioprocess America, Inc. | System for performing cleavage, deprotection, ultrafiltration, and diafiltration operations |
| IT202300017964A1 (it) * | 2023-08-31 | 2025-03-03 | Antoni Bellussi | Impianto di filtrazione di sostanze semisolide e liquide di vario genere e metodo di funzonamento di tale impianto |
| WO2025087829A1 (en) * | 2023-10-24 | 2025-05-01 | Merck Patent Gmbh | Continuous filtration by means of feed cycling |
| SE547261C2 (en) * | 2024-02-20 | 2025-06-17 | Helios Innovations AB | Method and system for managing process fluid |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5871652A (en) | 1995-08-04 | 1999-02-16 | Pipetronics, Inc. | Method for high volume pipeline water filtration |
| JP2000126767A (ja) * | 1998-10-21 | 2000-05-09 | Toray Ind Inc | 精製水の製造方法および装置 |
| US7384549B2 (en) * | 2005-12-29 | 2008-06-10 | Spf Innovations, Llc | Method and apparatus for the filtration of biological solutions |
| JP4805201B2 (ja) * | 2007-03-22 | 2011-11-02 | 月島環境エンジニアリング株式会社 | 膜分離を用いた目的物質の分離方法と装置 |
| US8147692B2 (en) * | 2008-01-04 | 2012-04-03 | Fluid Equipment Development Company, Llc | Batch-operated reverse osmosis system with multiple membranes in a pressure vessel |
| WO2010090864A2 (en) * | 2009-01-21 | 2010-08-12 | Smartflow Technologies, Inc. | Optimization of separation for viscous suspensions |
| EP2644259A1 (en) | 2012-03-29 | 2013-10-02 | Roche Diagniostics GmbH | Micro flow filtration system and flow filtration method |
| EP2682168A1 (en) * | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
| CN104583386A (zh) * | 2012-08-20 | 2015-04-29 | 泰尔茂比司特公司 | 浓缩穿过细胞生长腔室循环的流体的组分 |
| US9770804B2 (en) * | 2013-03-18 | 2017-09-26 | Versum Materials Us, Llc | Slurry supply and/or chemical blend supply apparatuses, processes, methods of use and methods of manufacture |
| US9821274B1 (en) * | 2014-02-09 | 2017-11-21 | Spf Innovations Llc | Hybrid diafiltration system and methods |
| EP3113865A4 (en) * | 2014-03-07 | 2017-11-01 | Agency For Science, Technology And Research | Apparatus and methods for fractionation of biological products |
| SG11201508664VA (en) | 2014-08-29 | 2016-03-30 | Emd Millipore Corp | Single Pass Tangential Flow Filtration Systems and Tangential Flow Filtration Systems withRecirculation of Retentate |
| CN111246930B (zh) | 2017-11-13 | 2022-12-02 | Emd密理博公司 | 通过罐循环的连续透滤 |
-
2018
- 2018-11-01 CN CN201880068067.5A patent/CN111246930B/zh active Active
- 2018-11-01 US US16/762,688 patent/US11691107B2/en active Active
- 2018-11-01 KR KR1020227011789A patent/KR20220050232A/ko not_active Ceased
- 2018-11-01 KR KR1020207013242A patent/KR102386215B1/ko active Active
- 2018-11-01 ES ES18804820T patent/ES2995480T3/es active Active
- 2018-11-01 WO PCT/US2018/058660 patent/WO2019094249A1/en not_active Ceased
- 2018-11-01 SG SG11202001497PA patent/SG11202001497PA/en unknown
- 2018-11-01 CA CA3080724A patent/CA3080724C/en active Active
- 2018-11-01 JP JP2020522302A patent/JP7177154B2/ja active Active
- 2018-11-01 EP EP18804820.1A patent/EP3710141B1/en active Active
- 2018-11-05 TW TW107139122A patent/TWI753216B/zh active
- 2018-11-05 TW TW111103761A patent/TWI788212B/zh active
-
2023
- 2023-03-14 US US18/183,609 patent/US12128359B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP7177154B2 (ja) | 2022-11-22 |
| CA3080724A1 (en) | 2019-05-16 |
| TW202220708A (zh) | 2022-06-01 |
| KR20220050232A (ko) | 2022-04-22 |
| US12128359B2 (en) | 2024-10-29 |
| ES2995480T3 (en) | 2025-02-10 |
| US20230211291A1 (en) | 2023-07-06 |
| KR20200060765A (ko) | 2020-06-01 |
| EP3710141B1 (en) | 2024-07-03 |
| WO2019094249A1 (en) | 2019-05-16 |
| CN111246930B (zh) | 2022-12-02 |
| CN111246930A (zh) | 2020-06-05 |
| EP3710141A1 (en) | 2020-09-23 |
| TWI753216B (zh) | 2022-01-21 |
| JP2021502232A (ja) | 2021-01-28 |
| KR102386215B1 (ko) | 2022-04-15 |
| CA3080724C (en) | 2023-04-25 |
| TWI788212B (zh) | 2022-12-21 |
| US20210170336A1 (en) | 2021-06-10 |
| US11691107B2 (en) | 2023-07-04 |
| TW201922305A (zh) | 2019-06-16 |
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