SG11202000565VA - Treatment of cancer by stimulation of il-12 production - Google Patents

Treatment of cancer by stimulation of il-12 production

Info

Publication number
SG11202000565VA
SG11202000565VA SG11202000565VA SG11202000565VA SG11202000565VA SG 11202000565V A SG11202000565V A SG 11202000565VA SG 11202000565V A SG11202000565V A SG 11202000565VA SG 11202000565V A SG11202000565V A SG 11202000565VA SG 11202000565V A SG11202000565V A SG 11202000565VA
Authority
SG
Singapore
Prior art keywords
stimulation
cancer
treatment
production
Prior art date
Application number
SG11202000565VA
Other languages
English (en)
Inventor
David Festus Charles Moffat
Martin John Perry
Stephen Mark Anderton
Clare Louise Doris
Original Assignee
Macrophage Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Macrophage Pharma Ltd filed Critical Macrophage Pharma Ltd
Publication of SG11202000565VA publication Critical patent/SG11202000565VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
SG11202000565VA 2017-08-31 2018-08-30 Treatment of cancer by stimulation of il-12 production SG11202000565VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1713975.9A GB201713975D0 (en) 2017-08-31 2017-08-31 Medical use
PCT/GB2018/052448 WO2019043389A1 (en) 2017-08-31 2018-08-30 TREATMENT OF CANCER BY STIMULATING IL-12 PRODUCTION

Publications (1)

Publication Number Publication Date
SG11202000565VA true SG11202000565VA (en) 2020-03-30

Family

ID=60050569

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000565VA SG11202000565VA (en) 2017-08-31 2018-08-30 Treatment of cancer by stimulation of il-12 production

Country Status (15)

Country Link
US (1) US11382902B2 (zh)
EP (1) EP3675851A1 (zh)
JP (1) JP2020536848A (zh)
KR (1) KR20200129086A (zh)
CN (1) CN111356457A (zh)
AU (1) AU2018326668A1 (zh)
BR (1) BR112020003033A2 (zh)
CA (1) CA3071550A1 (zh)
GB (1) GB201713975D0 (zh)
IL (1) IL272769A (zh)
MA (1) MA50030A (zh)
MX (1) MX2020001197A (zh)
RU (1) RU2020111355A (zh)
SG (1) SG11202000565VA (zh)
WO (1) WO2019043389A1 (zh)

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WO2003068746A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Aryl ureas as kinase inhibitors
ATE485275T1 (de) 2002-02-12 2010-11-15 Glaxosmithkline Llc Nicotinamide und deren verwendung als p38 inhibitoren
BR0308429A (pt) 2002-03-14 2005-01-11 Bayer Healthcare Ag Aroilpiridinonas monocìclicas como agentes antiinflamatórios
US20060079461A1 (en) * 2003-12-24 2006-04-13 Scios, Inc. Treatment of multiple myeloma by inhibition of p38 MAP kinase
GB0509223D0 (en) 2005-05-05 2005-06-15 Chroma Therapeutics Ltd Enzyme inhibitors
GB0509225D0 (en) 2005-05-05 2005-06-15 Chroma Therapeutics Ltd Inhibitors of enzymatic activity
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WO2006117567A2 (en) 2005-05-05 2006-11-09 Chroma Therapeutics Ltd Alpha aminoacid ester-drug conjugates hydrolysable by carboxylesterase
GB0510204D0 (en) 2005-05-19 2005-06-22 Chroma Therapeutics Ltd Enzyme inhibitors
GB0608837D0 (en) 2006-05-04 2006-06-14 Chroma Therapeutics Ltd Inhibitors of MAP kinase
GB0608823D0 (en) 2006-05-04 2006-06-14 Chroma Therapeutics Ltd Inhibitors of P13 kinase
GB0608821D0 (en) 2006-05-04 2006-06-14 Chroma Therapeutics Ltd DHFR enzyme inhibitors
CA2650970C (en) 2006-05-04 2014-09-16 Chroma Therapeutics Ltd. P38 map kinase inhibitors
GB0619753D0 (en) 2006-10-06 2006-11-15 Chroma Therapeutics Ltd Enzyme inhibitors
JP2010507639A (ja) 2006-10-25 2010-03-11 クロマ セラピューティクス リミテッド 癌の治療に有用なポロ様キナーゼ阻害剤としてのプテリジン誘導体
GB0621203D0 (en) 2006-10-25 2006-12-06 Chroma Therapeutics Ltd PLK inhibitors
BRPI0622100A2 (pt) 2006-10-30 2011-12-27 Chroma Therapeutics Ltd hidroxamatos como inibidores de desacetilase de histona
AU2007315943A1 (en) 2006-11-01 2008-05-08 Chroma Therapeutics Ltd. IKK-beta serine-threonine protein kinase inhibitors
WO2008053185A1 (en) 2006-11-01 2008-05-08 Chroma Therapeutics Ltd. INHIBITORS OF IKK-β SERINE-THREONINE PROTEIN KINASE
JO2985B1 (ar) 2006-12-20 2016-09-05 Takeda Pharmaceuticals Co مثبطات كينازmapk/erk
WO2009060160A1 (en) 2007-11-07 2009-05-14 Chroma Therapeutics Ltd. P38 map kinase inhibitors
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EA201001694A1 (ru) 2008-04-23 2011-06-30 Хрома Терапьютикс Лтд. Ингибиторы ikk-бета серин-треонин протеинкиназ
GB0807451D0 (en) 2008-04-24 2008-05-28 Chroma Therapeutics Ltd Inhibitors of PLK
BRPI0911480A2 (pt) 2008-04-26 2018-04-03 Chroma Therapeutics Ltd inibidores de proteínas serina-treonina quinase ikk-beta
GB0903480D0 (en) 2009-02-27 2009-04-08 Chroma Therapeutics Ltd Enzyme Inhibitors
GB0907120D0 (en) 2009-04-24 2009-06-03 Chroma Therapeutics Ltd Inhibitors of IKK-ß serine-threonine protein kinase
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GB201021467D0 (en) 2010-12-17 2011-02-02 Chroma Therapeutics Ltd Imaging agents
JP6005751B2 (ja) * 2011-10-21 2016-10-12 トランジェーヌ、ソシエテ、アノニムTransgene S.A. マクロファージの活性化の調節
GB201211310D0 (en) 2012-06-26 2012-08-08 Chroma Therapeutics Ltd CSF-1R kinase inhibitors
US9388136B2 (en) * 2012-10-17 2016-07-12 Chroma Therapeutics Ltd Tert-butyl N-[2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]-3,5-difluorophenyl}ethyl]-L-alaninate or a salt, hydrate or solvate thereof
GB201306901D0 (en) * 2013-04-16 2013-05-29 Chroma Therapeutics Ltd Combination

Also Published As

Publication number Publication date
RU2020111355A (ru) 2021-09-30
MX2020001197A (es) 2020-08-13
US20200360359A1 (en) 2020-11-19
EP3675851A1 (en) 2020-07-08
BR112020003033A2 (pt) 2020-08-04
AU2018326668A1 (en) 2020-02-20
WO2019043389A1 (en) 2019-03-07
JP2020536848A (ja) 2020-12-17
RU2020111355A3 (zh) 2021-12-16
CA3071550A1 (en) 2019-03-07
MA50030A (fr) 2020-07-08
IL272769A (en) 2020-04-30
KR20200129086A (ko) 2020-11-17
CN111356457A (zh) 2020-06-30
GB201713975D0 (en) 2017-10-18
US11382902B2 (en) 2022-07-12

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