SG11202000269PA - Method for incubating liquids and inactivating viruses - Google Patents

Method for incubating liquids and inactivating viruses

Info

Publication number
SG11202000269PA
SG11202000269PA SG11202000269PA SG11202000269PA SG11202000269PA SG 11202000269P A SG11202000269P A SG 11202000269PA SG 11202000269P A SG11202000269P A SG 11202000269PA SG 11202000269P A SG11202000269P A SG 11202000269PA SG 11202000269P A SG11202000269P A SG 11202000269PA
Authority
SG
Singapore
Prior art keywords
international
vienna
incubating
pct
liquids
Prior art date
Application number
SG11202000269PA
Other languages
English (en)
Inventor
Nikolaus Hammerschmidt
Jure Sencar
Alois Jungbauer
Duarte Lima Martins
Original Assignee
Baxalta Inc
Baxalta GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta Inc, Baxalta GmbH filed Critical Baxalta Inc
Publication of SG11202000269PA publication Critical patent/SG11202000269PA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/45Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4524Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through foam-like inserts or through a bed of loose bodies, e.g. balls
    • B01F25/45241Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through foam-like inserts or through a bed of loose bodies, e.g. balls through a bed of balls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30Micromixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • C12N7/06Inactivation or attenuation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/00061Methods of inactivation or attenuation
    • C12N2760/00063Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202000269PA 2017-07-10 2018-07-10 Method for incubating liquids and inactivating viruses SG11202000269PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17180477 2017-07-10
EP18154196 2018-01-30
PCT/EP2018/068628 WO2019011900A1 (en) 2017-07-10 2018-07-10 METHOD FOR LIQUID INCUBATION AND VIRUS INACTIVATION

Publications (1)

Publication Number Publication Date
SG11202000269PA true SG11202000269PA (en) 2020-02-27

Family

ID=63209374

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000269PA SG11202000269PA (en) 2017-07-10 2018-07-10 Method for incubating liquids and inactivating viruses

Country Status (11)

Country Link
US (1) US20190022654A1 (zh)
EP (1) EP3651811A1 (zh)
JP (1) JP7218344B2 (zh)
KR (1) KR102623471B1 (zh)
CN (1) CN111050809B (zh)
AU (1) AU2018299920B2 (zh)
CA (1) CA3069593A1 (zh)
CO (1) CO2020001426A2 (zh)
MX (1) MX2020000353A (zh)
SG (1) SG11202000269PA (zh)
WO (1) WO2019011900A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3072885B1 (fr) * 2017-10-27 2019-11-15 IFP Energies Nouvelles Nouveau systeme de distribution par panneaux meridiens pour un procede de separation en lit mobile simule utilisant n-colonnes en serie
DE102018009597A1 (de) * 2018-12-07 2020-06-10 Sartorius Stedim Biotech Gmbh Vorrichtung und Verfahren zur mehrfachen Änderung der Zusammensetzung eines Fluids
WO2021222735A1 (en) * 2020-04-30 2021-11-04 Massachusetts Institute Of Technology Model-based control for column-based continuous viral inactivation of biopharmaceuticals
US20220146485A1 (en) * 2020-11-12 2022-05-12 Essen Instruments, Inc. D/B/A Essen Bioscience, Inc. Viral clearance evaluation for biological medical product preparation processes

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
AU2001227653A1 (en) * 2000-03-09 2001-09-17 Transgenomic, Inc. Method and system for rna analysis by matched ion polynucleotide chromatography
IL136552A (en) 2000-06-05 2005-05-17 Omrix Biopharmaceuticals Ltd Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration
CN1725998A (zh) * 2002-12-12 2006-01-25 旭化成株式会社 病毒除去袋及使用该病毒除去袋除去病毒的方法
EP1615959B1 (en) 2003-04-10 2013-06-05 Evonik Corporation A method for the production of emulsion-based micro particles
AU2005229674B2 (en) * 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
BR112013013884A2 (pt) * 2010-12-06 2016-09-13 Pall Corp métodos de processamento contínuo para produtos biológicos
KR101854310B1 (ko) * 2010-12-15 2018-05-04 박스알타 인코퍼레이티드 개선된 용매-세제법을 이용한 바이러스 불활성화
US9028678B2 (en) * 2011-06-28 2015-05-12 Phillips 66 Company Scrubbing hydrogen sulfide from hydrotreated product
EP2578286A1 (en) * 2011-10-04 2013-04-10 Merck Patent GmbH Method and apparatus for chromatographic purification
KR102065355B1 (ko) 2012-05-31 2020-01-13 에이전시 포 사이언스, 테크놀로지 앤드 리서치 단백질 제조물 내의 응집체 양 감소를 위한 혼합 다관능 표면들의 사용 방법
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
ES2900425T3 (es) * 2013-09-25 2022-03-16 Bioverativ Therapeutics Inc Métodos de inactivación vírica en columna
EP2918294A1 (de) 2014-03-11 2015-09-16 Bayer Technology Services GmbH Vorrichtung und Verfahren zur kontinuierlichen Virusinaktivierung
EP3131589B1 (en) 2014-04-15 2023-05-17 Boehringer Ingelheim International GmbH Method and use for continuously inactivating a virus during manufacture of a biological product
EP3088006A1 (de) 2015-04-28 2016-11-02 Bayer Technology Services GmbH Verfahren zur kontinuierlichen virusinaktivierung in einem mikroreaktor
EP3141611A3 (en) * 2016-10-21 2017-05-10 Bayer Healthcare LLC Validation of continuous viral clearance

Also Published As

Publication number Publication date
CA3069593A1 (en) 2019-01-17
EP3651811A1 (en) 2020-05-20
KR102623471B1 (ko) 2024-01-09
WO2019011900A1 (en) 2019-01-17
MX2020000353A (es) 2020-08-17
RU2020105866A3 (zh) 2022-02-25
CN111050809A (zh) 2020-04-21
JP7218344B2 (ja) 2023-02-06
AU2018299920A1 (en) 2020-02-06
US20190022654A1 (en) 2019-01-24
AU2018299920B2 (en) 2024-04-11
CN111050809B (zh) 2021-12-24
JP2020526210A (ja) 2020-08-31
CO2020001426A2 (es) 2020-02-28
RU2020105866A (ru) 2021-08-10
KR20200026955A (ko) 2020-03-11
BR112020000524A2 (pt) 2020-07-21

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