SG11201811468UA - Fluid control - Google Patents

Fluid control

Info

Publication number
SG11201811468UA
SG11201811468UA SG11201811468UA SG11201811468UA SG11201811468UA SG 11201811468U A SG11201811468U A SG 11201811468UA SG 11201811468U A SG11201811468U A SG 11201811468UA SG 11201811468U A SG11201811468U A SG 11201811468UA SG 11201811468U A SG11201811468U A SG 11201811468UA
Authority
SG
Singapore
Prior art keywords
manor
international
lumiradx
loan
pct
Prior art date
Application number
SG11201811468UA
Inventor
Steven Alexander Keatch
Phil Lowe
Brian Mcguigan
Andrew Peter Phelan
Aman Khan
Original Assignee
Lumiradx Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lumiradx Uk Ltd filed Critical Lumiradx Uk Ltd
Publication of SG11201811468UA publication Critical patent/SG11201811468UA/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B13/00—Pumps specially modified to deliver fixed or variable measured quantities
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B35/00—Piston pumps specially adapted for elastic fluids and characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for
    • F04B35/01—Piston pumps specially adapted for elastic fluids and characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for the means being mechanical
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/04—Pumps having electric drive
    • F04B43/043—Micropumps
    • F04B43/046—Micropumps with piezoelectric drive
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B45/00—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
    • F04B45/06—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids having tubular flexible members
    • F04B45/067—Pumps having electric drive
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B45/00—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
    • F04B45/08—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids having peristaltic action
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04F—PUMPING OF FLUID BY DIRECT CONTACT OF ANOTHER FLUID OR BY USING INERTIA OF FLUID TO BE PUMPED; SIPHONS
    • F04F1/00—Pumps using positively or negatively pressurised fluid medium acting directly on the liquid to be pumped
    • F04F1/02—Pumps using positively or negatively pressurised fluid medium acting directly on the liquid to be pumped using both positively and negatively pressurised fluid medium, e.g. alternating
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04F—PUMPING OF FLUID BY DIRECT CONTACT OF ANOTHER FLUID OR BY USING INERTIA OF FLUID TO BE PUMPED; SIPHONS
    • F04F1/00—Pumps using positively or negatively pressurised fluid medium acting directly on the liquid to be pumped
    • F04F1/06—Pumps using positively or negatively pressurised fluid medium acting directly on the liquid to be pumped the fluid medium acting on the surface of the liquid to be pumped
    • F04F1/10—Pumps using positively or negatively pressurised fluid medium acting directly on the liquid to be pumped the fluid medium acting on the surface of the liquid to be pumped of multiple type, e.g. with two or more units in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1484—Electro-optical investigation, e.g. flow cytometers microstructural devices
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N—ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N30/00—Piezoelectric or electrostrictive devices
    • H10N30/20—Piezoelectric or electrostrictive devices with electrical input and mechanical output, e.g. functioning as actuators or vibrators
    • H10N30/204—Piezoelectric or electrostrictive devices with electrical input and mechanical output, e.g. functioning as actuators or vibrators using bending displacement, e.g. unimorph, bimorph or multimorph cantilever or membrane benders
    • H10N30/2041—Beam type
    • H10N30/2042—Cantilevers, i.e. having one fixed end
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0484—Cantilevers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0694—Valves, specific forms thereof vents used to stop and induce flow, backpressure valves

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD 1101111 0 DOI HIM 011101 0 01111111111111111111111111011111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2018/002668 Al 04 January 2018 (04.01.2018) W I PO I PCT (51) International Patent Classification: Gloucestershire GL52 ORJ (GB). KHAN, Aman; 56 Ash- BOIL 3/00 (2006.01) HOlL 41/09 (2006.01) mead Road, Bedford, Bedfordshire MK41 7GA (GB). F04B 43/04 (2006.01) (74) Agent: MARKS & CLERK LLP; CHAPMAN, Paul, (21) International Application Number: Atholl Exchange, 6 Canning Street, Edinburgh EH3 8EG PCT/GB2017/051946 (GB). (22) International Filing Date: (81) Designated States (unless otherwise indicated, for every 30 June 2017 (30.06.2017) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (25) Filing Language: English CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (26) Publication Language: English DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (30) Priority Data: HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, 1611442.3 30 June 2016 (30.06.2016) GB MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (71) Applicant: LUMIRADX UK LTD [GB/GB]; 3 More Lon- OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, don Riverside, London SE1 2AQ (GB). SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (72) Inventors: KLATCH, Steven Alexander; LumiraDx Technology Ltd, Unit 4 Block 3, Manor Farm Business (84) Designated States (unless otherwise indicated, for every Park, Manor Loan, Stirling FK9 5QD (GB). LOWE, Phil; kind of regional protection available): ARIPO (BW, GH, _ LumiraDx Technology Ltd, Unit 4 Block 3, Manor Farm GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, Business Park, Manor Loan, Stirling FK9 5QD (GB). UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, = MCGUIGAN, Brian; LumiraDx Technology Ltd, Unit 4 TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Block 3, Manor Farm Business Park, Manor Loan, Stir- EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, = ling FK9 5QD (GB). PHELAN, Andrew Peter; 12 Wood- MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, — mancote Vale, Woodmancote, Manor Loan, Cheltenham, = = = (54) Title: FLUID CONTROL (57) : The present invention relates to a microfluidic assay system and associated = = reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using a disposable system and associated = = = - = = = = 13 24 22 20 26 \ 4 10 \ 24 22 20 10 M 24 22 20 .. ' 4 10 \/ 26-V 10 S 24 22 20 ----32 ----A ------28 O - reading device, as well as kits for conducting assays. A - 11 GC ei © © 5 1 5 -.... Il Figure 1 0 ei C [Continued on next page] WO 2018/002668 Al MIDEDIM01101 DIDIIMEN0 V110EE11111111111101111111111111111111 TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))
SG11201811468UA 2016-06-30 2017-06-30 Fluid control SG11201811468UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1611442.3A GB201611442D0 (en) 2016-06-30 2016-06-30 Fluid control
PCT/GB2017/051946 WO2018002668A1 (en) 2016-06-30 2017-06-30 Fluid control

Publications (1)

Publication Number Publication Date
SG11201811468UA true SG11201811468UA (en) 2019-01-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201811468UA SG11201811468UA (en) 2016-06-30 2017-06-30 Fluid control

Country Status (16)

Country Link
US (2) US11000847B2 (en)
EP (2) EP3478410B1 (en)
JP (2) JP2019520580A (en)
KR (1) KR102472562B1 (en)
CN (1) CN109475863B (en)
AU (1) AU2017289723B2 (en)
CA (1) CA3029385C (en)
ES (1) ES2906129T3 (en)
GB (1) GB201611442D0 (en)
IL (1) IL263698B (en)
MX (1) MX2018015704A (en)
MY (1) MY190947A (en)
RU (1) RU2734293C2 (en)
SG (1) SG11201811468UA (en)
WO (1) WO2018002668A1 (en)
ZA (1) ZA201900232B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201014805D0 (en) 2010-09-07 2010-10-20 Multi Sense Technologies Ltd Microfluidics based assay device
US9933445B1 (en) 2016-05-16 2018-04-03 Hound Labs, Inc. System and method for target substance identification
US11056223B1 (en) * 2017-12-27 2021-07-06 Invoy Holdings Inc. Health monitoring and coaching system
JP7441827B2 (en) 2018-09-19 2024-03-01 ルミラディーエックス ユーケイ リミテッド analysis
USD912843S1 (en) 2018-11-06 2021-03-09 Lumiradx Uk Ltd Test strip
GB201818412D0 (en) 2018-11-12 2018-12-26 Lumiradx Tech Ltd A magnetic assembly for use in a device for conducting assays
CN109709316A (en) * 2018-12-27 2019-05-03 天津昌和生物医药技术有限公司 A kind of more target item miniflow test cards and preparation method
US20200245899A1 (en) 2019-01-31 2020-08-06 Hound Labs, Inc. Mechanical Breath Collection Device
JP2020134150A (en) * 2019-02-13 2020-08-31 株式会社フコク Microchannel chip
CN110437978A (en) * 2019-08-12 2019-11-12 北京航空航天大学 The integrated detection micro-fluidic chip of bacteria total amount, bacterial spore amount
CN112403539A (en) * 2019-08-23 2021-02-26 无锡源清天木生物科技有限公司 Micro-fluidic chip
CN111289425B (en) * 2020-03-12 2021-03-30 中国计量科学研究院 Protein content measurement reference method based on fluorescence labeling flow type single molecule counting
GB202006306D0 (en) 2020-04-29 2020-06-10 Lumiradx Tech Ltd Antibody/antigen detection
US11933731B1 (en) 2020-05-13 2024-03-19 Hound Labs, Inc. Systems and methods using Surface-Enhanced Raman Spectroscopy for detecting tetrahydrocannabinol
CN111782292B (en) * 2020-06-24 2024-04-02 江西景旺精密电路有限公司 Automatic loading method and device for hole inspection information
EP4243984A1 (en) * 2020-11-10 2023-09-20 Lumiradx Uk Ltd System for detection of a target in a liquid sample
WO2022147348A1 (en) * 2020-12-31 2022-07-07 Fluxergy Inc. Multimodal test cards
US11806711B1 (en) 2021-01-12 2023-11-07 Hound Labs, Inc. Systems, devices, and methods for fluidic processing of biological or chemical samples using flexible fluidic circuits
CN112508464B (en) * 2021-02-08 2021-06-01 常州微亿智造科技有限公司 Product detection method and device based on injection molding
FR3120126A1 (en) * 2021-02-23 2022-08-26 Magia Diagnostics Analysis cartridge and device for analyzing a liquid
CN113009167B (en) * 2021-02-23 2022-06-24 山东美毅生物技术有限公司 Micro-operation device capable of realizing accurate control of liquid suction and discharge
EP4326441A1 (en) * 2021-04-20 2024-02-28 miDiagnostics NV Microfluidic system
US20230191405A1 (en) * 2021-12-22 2023-06-22 Illumina, Inc. Instruments, systems, and methods for measuring liquid flow through channels
WO2023141199A2 (en) * 2022-01-21 2023-07-27 Trustees Of Dartmouth College Microtransfer patterning of magnetic materials for microfluidic applications

Family Cites Families (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4806313A (en) 1985-04-12 1989-02-21 E. I. Du Pont De Nemours And Company Rapid assay processor
US4772550A (en) 1986-02-10 1988-09-20 Miles Inc. Heterogeneous specific binding assay employing an aggregatable binding reagent
US5145784A (en) 1988-05-04 1992-09-08 Cambridge Biotech Corporation Double capture assay method employing a capillary flow device
US5096669A (en) 1988-09-15 1992-03-17 I-Stat Corporation Disposable sensing device for real time fluid analysis
US5698448A (en) 1988-12-02 1997-12-16 Soldin; Steven J. Immunosuppressive drug binding proteins and use
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
GB9122180D0 (en) 1991-10-18 1991-11-27 Marconi Gec Ltd Separation and analysis
US5637469A (en) 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
ATE185197T1 (en) 1993-04-29 1999-10-15 Danfoss As DEVICE FOR ANALYZING A LIQUID
US5821399A (en) 1993-07-16 1998-10-13 I-Stat Corporation Automatic test parameters compensation of a real time fluid analysis sensing device
US5674681A (en) 1994-12-06 1997-10-07 Rothenberg; Barry E. Methods to identify hemochromatosis
AU6541596A (en) 1995-06-16 1997-01-15 University Of Washington Microfabricated differential extraction device and method
JP3213566B2 (en) * 1996-04-26 2001-10-02 アークレイ株式会社 Sample analysis tool, sample analysis method and sample analyzer using the same
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6982146B1 (en) 1999-08-30 2006-01-03 The United States Of America As Represented By The Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
AU2002241595A1 (en) 2000-12-01 2002-07-24 Protasis Corporation Microfluidic device with multiple microcoil nmr detectors
US20030040129A1 (en) 2001-08-20 2003-02-27 Shah Haresh P. Binding assays using magnetically immobilized arrays
GB0129816D0 (en) 2001-12-13 2002-01-30 The Technology Partnership Plc Testing device for chemical or biochemical analysis
US20050170490A1 (en) * 2002-01-31 2005-08-04 Chen Yihfar Processes for manufacturing optical analysis discs with molded microfluidic structures and discs made according thereto
US7419821B2 (en) 2002-03-05 2008-09-02 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
US6843263B2 (en) * 2002-06-24 2005-01-18 Industrial Technology Research Institute Partially closed microfluidic system and microfluidic driving method
JP4057967B2 (en) 2002-07-31 2008-03-05 株式会社東芝 Automatic nucleotide sequence analyzer
KR100480338B1 (en) 2002-08-08 2005-03-30 한국전자통신연구원 Microfluidic devices for the controlled movements of solution
US7932098B2 (en) 2002-10-31 2011-04-26 Hewlett-Packard Development Company, L.P. Microfluidic system utilizing thin-film layers to route fluid
CN102620959B (en) 2002-12-26 2015-12-16 梅索磅秤技术有限公司 Assay cartridges and using method thereof
US7338637B2 (en) 2003-01-31 2008-03-04 Hewlett-Packard Development Company, L.P. Microfluidic device with thin-film electronic devices
JP4111505B2 (en) 2003-03-31 2008-07-02 キヤノン株式会社 Biochemical treatment apparatus and biochemical treatment method
US7341841B2 (en) 2003-07-12 2008-03-11 Accelr8 Technology Corporation Rapid microbial detection and antimicrobial susceptibility testing
EP2402089A1 (en) * 2003-07-31 2012-01-04 Handylab, Inc. Processing particle-containing samples
US7347617B2 (en) 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
US7682833B2 (en) 2003-09-10 2010-03-23 Abbott Point Of Care Inc. Immunoassay device with improved sample closure
WO2005030033A2 (en) 2003-09-22 2005-04-07 Battelle Memorial Institute Fluid sample test device
EP1690085B1 (en) 2003-11-05 2018-06-06 Separation Technology, Inc. Disposable fluid sample collection device
US8057740B2 (en) 2004-06-23 2011-11-15 Tesa Se Medical biosensor by means of which biological liquids are analyzed
DE102004046366A1 (en) 2004-07-15 2006-02-09 Levin, Felix, Dr. Rapid chemical analysis system for urine or other biological fluids has pipette with rubber balloon and chemical reagent on inside surface of balloon or in filter plug
KR100705361B1 (en) * 2004-08-21 2007-04-10 주식회사 엘지생명과학 A Capillary Flow Control Module and Lab-on-a-chip Equipped with the Same
EP1807208B1 (en) 2004-10-15 2013-03-20 Siemens Aktiengesellschaft Arrangement for integrated and automated dna or protein analysis in a single-use cartridge, method for producing such a cartridge and operating method for dna or protein analysis using such a cartridge
GB0506183D0 (en) 2005-03-24 2005-05-04 Univ Edinburgh Antigen detection
US20060257958A1 (en) 2005-05-13 2006-11-16 Pronucleotein Biotechnologies, Llc Magnetically-assisted test strip cartridge and method for using same
WO2006125767A1 (en) 2005-05-25 2006-11-30 Siemens Aktiengesellschaft System for the integrated and automated analysis of dna or protein and method for operating said type of system
US20070031283A1 (en) 2005-06-23 2007-02-08 Davis Charles Q Assay cartridges and methods for point of care instruments
US20090130771A1 (en) 2005-07-20 2009-05-21 Inverness Medical Switzerland Gmbh Assay device and method
CA2637837A1 (en) 2006-01-26 2007-08-09 Hx Diagnostics, Inc. Monoclonal antibodies binding to avian influenza virus subtype h5 haemagglutinin and uses thereof
JP5415253B2 (en) * 2006-03-24 2014-02-12 ハンディラブ・インコーポレーテッド Integrated system for processing microfluidic samples and methods of use thereof
GB2436616A (en) 2006-03-29 2007-10-03 Inverness Medical Switzerland Assay device and method
CN101467045A (en) 2006-06-15 2009-06-24 皇家飞利浦电子股份有限公司 Increased specificity of analyte detection by measurement of bound and unbound labels
JP2007333706A (en) 2006-06-19 2007-12-27 Sekisui Chem Co Ltd Cartridge type detection device
ATE517345T1 (en) 2006-07-19 2011-08-15 Koninkl Philips Electronics Nv METHOD FOR ANALYZING SAMPLES USING A GAS EVOLUTION AGENT
GB0618966D0 (en) 2006-09-26 2006-11-08 Iti Scotland Ltd Cartridge system
GB2443694B (en) 2006-11-10 2011-09-14 Platform Diagnostics Ltd Analyte saturation assay, methods and kits and devices
WO2009108260A2 (en) 2008-01-22 2009-09-03 Microchip Biotechnologies, Inc. Universal sample preparation system and use in an integrated analysis system
GB0805296D0 (en) 2008-03-20 2008-04-30 Iti Scotland Ltd Uses of reagents in sample collection and cartridge systems
KR101605575B1 (en) 2008-03-31 2016-03-22 키아겐 라케 콘스탄스 게엠베하 Sample holder and method of using the same
KR101102532B1 (en) 2008-07-10 2012-01-03 삼성전자주식회사 Cartridge containing reagent therein, microfluidic device having the cartridge, manufacturing method of the microfluidic device, biochemistry analysis method using microfluidic device
WO2010012281A1 (en) 2008-07-29 2010-02-04 Jacques Jonsmann A microfluidic device
JP2010117308A (en) 2008-11-14 2010-05-27 Fujifilm Corp Detection method of fluorescence quenching material in gaseous phase
GB0919159D0 (en) 2009-11-02 2009-12-16 Sec Dep For Environment Food A Device and apparatus
WO2013142847A1 (en) 2012-03-22 2013-09-26 Cyvek, Inc Pdms membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them
SG174649A1 (en) 2010-03-30 2011-10-28 Clearbridge Bioloc Pte Ltd Assay
US9233370B2 (en) 2010-08-05 2016-01-12 Abbott Point Of Care Inc. Magnetic immunosensor and method of use
WO2012019104A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Immunoassay method and device with magnetically susceptible bead capture
GB201014805D0 (en) 2010-09-07 2010-10-20 Multi Sense Technologies Ltd Microfluidics based assay device
WO2012037369A1 (en) * 2010-09-15 2012-03-22 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
GB201102037D0 (en) 2011-02-07 2011-03-23 Multi Sense Technologies Ltd Microfluidics based assay device
CN106552682B (en) 2011-03-22 2020-06-19 西维克公司 Microfluidic device and methods of manufacture and use
JP2014224679A (en) * 2011-09-06 2014-12-04 コニカミノルタ株式会社 Micro-flow path device and micro-flow path analyzer
US8435738B2 (en) 2011-09-25 2013-05-07 Theranos, Inc. Systems and methods for multi-analysis
US9140693B2 (en) 2011-12-23 2015-09-22 Abbott Point Of Care Inc. Integrated test device for optical detection of microarrays
WO2013096801A1 (en) 2011-12-23 2013-06-27 Abbott Point Of Care Inc Reader devices for optical and electrochemical test devices
KR101338175B1 (en) 2012-01-13 2013-12-09 주식회사 아이센스 Cartridge for sensing elements in a sample
WO2013135713A1 (en) 2012-03-12 2013-09-19 Biosurfit S.A. Liquid sample imaging device and method
CN104204800A (en) 2012-04-11 2014-12-10 美艾利尔圣地亚哥公司 Microfluidic device, system and method
US20130299003A1 (en) * 2012-05-09 2013-11-14 David J. Beebe Method And Device For Actuating Fluid Flow In A Microchannel
FR2991055B1 (en) 2012-05-22 2014-06-13 C2 Diagnostics FLUIDIC CONNECTION DEVICE FOR BIOLOGICAL ANALYSIS APPARATUS, FLUIDIC COMPONENT ADAPTED AND BIOLOGICAL ANALYSIS APPARATUS THUS EQUIPPED THEREFOR;
DE102012018029B4 (en) 2012-09-13 2019-03-07 Thomas Magnete Gmbh Device for tempering with a piezoelectrically driven compressor unit and method for control
CA2889415C (en) * 2012-10-24 2020-06-02 Genmark Diagnostics, Inc. Integrated multiplex target analysis
GB2516675A (en) 2013-07-29 2015-02-04 Atlas Genetics Ltd A valve which depressurises, and a valve system
GB2516672B (en) * 2013-07-29 2015-05-20 Atlas Genetics Ltd A system and method for expelling liquid from a fluidic cartridge
CN105939779A (en) * 2013-09-18 2016-09-14 加州理工学院 System and method for movement and timing control
CN107076770B (en) 2014-07-28 2019-07-12 道格拉斯科学有限责任公司 For analyzing the instrument of biological sample and reagent

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