SG11201808650QA - Methods of treating ocular conditions - Google Patents

Methods of treating ocular conditions

Info

Publication number
SG11201808650QA
SG11201808650QA SG11201808650QA SG11201808650QA SG11201808650QA SG 11201808650Q A SG11201808650Q A SG 11201808650QA SG 11201808650Q A SG11201808650Q A SG 11201808650QA SG 11201808650Q A SG11201808650Q A SG 11201808650QA SG 11201808650Q A SG11201808650Q A SG 11201808650QA
Authority
SG
Singapore
Prior art keywords
international
day
rat
pct
methods
Prior art date
Application number
SG11201808650QA
Other languages
English (en)
Inventor
Douglas Michael Ackermann
James Loudin
Kenneth J Mandell
Original Assignee
Oyster Point Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oyster Point Pharma Inc filed Critical Oyster Point Pharma Inc
Publication of SG11201808650QA publication Critical patent/SG11201808650QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SG11201808650QA 2016-04-07 2017-04-06 Methods of treating ocular conditions SG11201808650QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662319648P 2016-04-07 2016-04-07
PCT/US2017/026385 WO2017177024A1 (en) 2016-04-07 2017-04-06 Methods of treating ocular conditions

Publications (1)

Publication Number Publication Date
SG11201808650QA true SG11201808650QA (en) 2018-10-30

Family

ID=58549326

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201808650QA SG11201808650QA (en) 2016-04-07 2017-04-06 Methods of treating ocular conditions

Country Status (20)

Country Link
US (3) US10709707B2 (enrdf_load_stackoverflow)
EP (2) EP3970724A1 (enrdf_load_stackoverflow)
JP (3) JP7090551B2 (enrdf_load_stackoverflow)
KR (2) KR102485299B1 (enrdf_load_stackoverflow)
CN (3) CN114533737B (enrdf_load_stackoverflow)
AU (1) AU2017248276B2 (enrdf_load_stackoverflow)
CA (1) CA3020170A1 (enrdf_load_stackoverflow)
DK (1) DK3439661T3 (enrdf_load_stackoverflow)
EA (1) EA201892265A1 (enrdf_load_stackoverflow)
ES (1) ES2893126T3 (enrdf_load_stackoverflow)
IL (3) IL299204A (enrdf_load_stackoverflow)
MX (2) MX385698B (enrdf_load_stackoverflow)
MY (1) MY199237A (enrdf_load_stackoverflow)
NZ (1) NZ746468A (enrdf_load_stackoverflow)
PH (1) PH12018502154A1 (enrdf_load_stackoverflow)
PT (1) PT3439661T (enrdf_load_stackoverflow)
SG (1) SG11201808650QA (enrdf_load_stackoverflow)
TW (2) TWI790997B (enrdf_load_stackoverflow)
WO (1) WO2017177024A1 (enrdf_load_stackoverflow)
ZA (1) ZA201807438B (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9145396B2 (en) 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
AU2015336216B2 (en) 2014-10-20 2020-05-21 Oyster Point Pharma, Inc. Methods of treating ocular conditions
CA3020170A1 (en) 2016-04-07 2017-10-12 Oyster Point Pharma, Inc. Methods of treating ocular conditions
WO2020014232A1 (en) 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions
WO2020014217A1 (en) 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Methods of treating ocular conditions
WO2021222230A1 (en) 2020-04-28 2021-11-04 Oyster Point Pharma, Inc. Local administration of nicotinic acetylcholine receptor agonists for the inhibition of coronavirus infections
MX2023013137A (es) * 2021-05-07 2024-02-23 Oyster Point Pharma Inc Coterapia con vector y agonista nicotínico.

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277855B1 (en) 2000-04-21 2001-08-21 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with nicotinic acetylcholine receptor agonists
US20030008892A1 (en) 2001-07-09 2003-01-09 Pfizer Inc. Pharmaceutical composition and method of modulating cholinergic function in a mammal
CA2468705A1 (en) 2001-11-29 2003-06-05 Pfizer Products Inc. Succinic acid salts of 5,8,14-triazatetracyclo'10.3.1.0<2,11>.0<4,9>-hexadeca-2(11),3,5,7,9-pentaene and pharmaceutical compositions thereof
WO2004039366A1 (en) * 2002-11-01 2004-05-13 Pharmacia & Upjohn Company Llc Nicotinic acetylcholine agonists in the treatment of glaucoma and retinal neuropathy
US7098331B2 (en) 2003-03-05 2006-08-29 Targacept, Inc. Arylvinylazacycloalkane compounds and methods of preparation and use thereof
US20060270592A1 (en) 2004-03-19 2006-11-30 Ophthalmic Research Associates, Inc. Use of neurotransmitters and neuropeptides for the treatment of dry eye diseases and related conditions
JP2008516942A (ja) 2004-10-15 2008-05-22 ファイザー・プロダクツ・インク バレニクリンの鼻腔内、バッカル、舌下および肺送達のための組成物および方法
US20090023819A1 (en) 2005-03-22 2009-01-22 Anders Axelsson Use of an Artificial Sweetener to Enhance Absorption of Nicotine
US20110086086A1 (en) 2005-07-26 2011-04-14 Pfizer Inc Transdermal system for varenicline
TWI404532B (zh) 2006-11-02 2013-08-11 Targacept Inc 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺
MX2009008284A (es) 2007-02-02 2009-08-12 Pfizer Prod Inc Compuestos triciclicos y su uso como moduladores de receptor de glucocorticoides.
WO2008157365A2 (en) * 2007-06-15 2008-12-24 Targacept, Inc. Vinylazacycloalkanes for treating neuropathic pain
US20090093446A1 (en) 2007-10-05 2009-04-09 Winston Laboratories, Inc. Method for alleviating keratoconjunctivitis sicca
CL2008003507A1 (es) 2007-11-26 2009-11-27 Neuroderm Ltd Composicion farmaceutica que comprende nicotina y un inhibidor de la desensibilizacion del receptor de acetilcolina nicotinico (nachr) opipramol; kit farmaceutico; dispositivo medico; y uso para tratar una enfermedad o trastorno del sistema nervioso central o periferico.
CN101959888A (zh) 2008-03-05 2011-01-26 塔加西普特公司 二氮杂双环烷烃的烟碱乙酰胆碱受体亚型的选择性酰胺
WO2010028011A1 (en) 2008-09-05 2010-03-11 Targacept, Inc. Amides of diazabicyclononanes and uses thereof
EP2344496A1 (en) 2008-09-05 2011-07-20 Targacept Inc. Amides of diazabicyclooctanes and uses thereof
MX2011003306A (es) * 2008-10-14 2011-09-01 Psychogenics Inc Ligandos nicotinicos de receptor de acetilcolina y los usos de los mismos.
US9145396B2 (en) * 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
TW201024283A (en) 2008-12-01 2010-07-01 Targacept Inc Synthesis and novel salt forms of (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine
BRPI0922759A2 (pt) * 2008-12-01 2016-01-05 Targacept Inc síntese e novas formas de sal de (r)-5((e)-2-(pirrolidin-3-ilvinil)pirimidina
CA2763551A1 (en) * 2009-06-17 2010-12-23 Targacept, Inc. Reversal of l-dopa-induced dyskinesia by neuronal nicotinic receptor ligands
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US8821457B2 (en) 2010-09-08 2014-09-02 Johnson & Johnson Vision Care, Inc. Punctal plug containing drug formulation
JO3766B1 (ar) 2011-10-20 2021-01-31 Novartis Ag منشط مستقبل أسيتيل كولين الفا - 7 النيكوتيني
EP3029463A1 (en) 2011-11-30 2016-06-08 DiagnosTear Ltd Dry eye diagnostic
AU2015336216B2 (en) 2014-10-20 2020-05-21 Oyster Point Pharma, Inc. Methods of treating ocular conditions
CA3020170A1 (en) 2016-04-07 2017-10-12 Oyster Point Pharma, Inc. Methods of treating ocular conditions

Also Published As

Publication number Publication date
IL290069A (en) 2022-03-01
WO2017177024A1 (en) 2017-10-12
US20250000861A1 (en) 2025-01-02
JP2022120125A (ja) 2022-08-17
PT3439661T (pt) 2021-09-30
IL262102B (en) 2022-03-01
ES2893126T8 (es) 2022-05-23
KR20230010813A (ko) 2023-01-19
EP3439661B1 (en) 2021-08-04
AU2017248276A1 (en) 2018-11-22
US20200345734A1 (en) 2020-11-05
IL290069B1 (en) 2023-01-01
CN114432313A (zh) 2022-05-06
CN109310692A (zh) 2019-02-05
KR20190005859A (ko) 2019-01-16
AU2017248276B2 (en) 2023-07-13
JP7090551B2 (ja) 2022-06-24
KR102512777B1 (ko) 2023-03-23
TWI790997B (zh) 2023-02-01
MX2021010399A (es) 2022-01-18
CN109310692B (zh) 2022-01-25
PH12018502154A1 (en) 2019-07-08
US10709707B2 (en) 2020-07-14
MX385698B (es) 2025-03-18
TWI876258B (zh) 2025-03-11
WO2017177024A8 (en) 2018-11-08
CN114533737B (zh) 2024-05-31
MY199237A (en) 2023-10-22
JP2024103594A (ja) 2024-08-01
EP3439661A1 (en) 2019-02-13
BR112018070497A2 (pt) 2019-01-29
TW201737917A (zh) 2017-11-01
MX2018012230A (es) 2019-03-28
ZA201807438B (en) 2024-09-25
IL299204A (en) 2023-02-01
IL290069B2 (en) 2023-05-01
TW202320785A (zh) 2023-06-01
NZ785093A (en) 2024-07-05
ES2893126T3 (es) 2022-02-08
CA3020170A1 (en) 2017-10-12
NZ746468A (en) 2023-06-30
DK3439661T3 (da) 2021-10-18
JP2019513759A (ja) 2019-05-30
US20190201397A1 (en) 2019-07-04
IL262102A (en) 2018-11-29
KR102485299B1 (ko) 2023-01-06
EA201892265A1 (ru) 2019-04-30
CN114533737A (zh) 2022-05-27
EP3970724A1 (en) 2022-03-23

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