SG11201802925YA - Integrated visual morphology and cell protein expression using resonance-light scattering - Google Patents

Integrated visual morphology and cell protein expression using resonance-light scattering

Info

Publication number
SG11201802925YA
SG11201802925YA SG11201802925YA SG11201802925YA SG11201802925YA SG 11201802925Y A SG11201802925Y A SG 11201802925YA SG 11201802925Y A SG11201802925Y A SG 11201802925YA SG 11201802925Y A SG11201802925Y A SG 11201802925YA SG 11201802925Y A SG11201802925Y A SG 11201802925YA
Authority
SG
Singapore
Prior art keywords
resonance
light scattering
protein expression
cell protein
integrated visual
Prior art date
Application number
SG11201802925YA
Other languages
English (en)
Inventor
Stephen Roman Fait
Eric Scott Mccampbell
Thomas H Adams
Michelle Brooke Mccampbell
Edward Jablonski
Robert Earl Klem
Original Assignee
Clearbridge Biophotonics Pte Ltd
Thomas H Adams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clearbridge Biophotonics Pte Ltd, Thomas H Adams filed Critical Clearbridge Biophotonics Pte Ltd
Publication of SG11201802925YA publication Critical patent/SG11201802925YA/en

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • G01N15/01—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
SG11201802925YA 2015-10-07 2016-10-06 Integrated visual morphology and cell protein expression using resonance-light scattering SG11201802925YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562238605P 2015-10-07 2015-10-07
PCT/US2016/055789 WO2017062646A1 (fr) 2015-10-07 2016-10-06 Analyse d'expression de protéine cellulaire et de morphologie visuelle intégrée faisant appel à la diffusion résonante de lumière

Publications (1)

Publication Number Publication Date
SG11201802925YA true SG11201802925YA (en) 2018-05-30

Family

ID=58488504

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201802925YA SG11201802925YA (en) 2015-10-07 2016-10-06 Integrated visual morphology and cell protein expression using resonance-light scattering

Country Status (4)

Country Link
US (1) US20170234874A1 (fr)
CN (1) CN108601525A (fr)
SG (1) SG11201802925YA (fr)
WO (1) WO2017062646A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10401346B2 (en) * 2016-09-16 2019-09-03 Rachel Olema Aitaru Mobile sickle cell diagnostic tool
US10801960B2 (en) * 2017-01-31 2020-10-13 Industry-University Cooperation Foundation Hanyang University Methods for detecting endocrine disruptors using dual modes of colorimetric and fluorometric analysis
WO2019004804A2 (fr) * 2017-06-30 2019-01-03 한국화학연구원 Kit de diagnostic de septicémie et procédé de diagnostic l'utilisant
CN107475202A (zh) * 2017-08-18 2017-12-15 河南省肿瘤医院 一种肺癌循环肿瘤细胞捕获与活性检测、分析方法及其应用
CN110785499A (zh) * 2018-05-25 2020-02-11 伊鲁米那股份有限公司 对先兆子痫具有特异性的循环rna标识
WO2020043693A1 (fr) * 2018-08-29 2020-03-05 Westfälische Wilhelms-Universität Münster Diagnostic de la sclérose en plaques
WO2020068905A1 (fr) * 2018-09-25 2020-04-02 Northwestern University Stabilisation de cristaux colloïdaux conçus avec un acide nucléique
CN110553888B (zh) * 2019-09-16 2022-07-12 中国农业科学院特产研究所 一种卵母细胞免疫荧光染色后快速压片的方法
CN113677807A (zh) 2019-11-22 2021-11-19 因美纳有限公司 先兆子痫特异性的循环rna标记
EP4126243A1 (fr) * 2020-03-27 2023-02-08 The Trustees of Indiana University Cibles immunothérapeutiques dans le myélome multiple et procédés pour leur identification
CN111693445A (zh) * 2020-06-05 2020-09-22 北京卓诚惠生生物科技股份有限公司 检测痰液中免疫细胞的方法
CN111821283B (zh) * 2020-07-23 2021-11-30 华侨大学 一种癌细胞膜包裹负载三苯基膦-氯尼达明的谷氨酸锌包裹普鲁士蓝纳米粒及其制备方法
CN114076721B (zh) * 2020-08-12 2023-09-12 宝山钢铁股份有限公司 钢板镀铬溶液使用寿命的检测方法
CN112345755B (zh) * 2020-09-23 2023-06-16 杭州凯保罗生物科技有限公司 乳腺癌的生物标志物及其应用
WO2022140576A1 (fr) * 2020-12-22 2022-06-30 The Brigham And Women's Hospital, Inc. Panel de biomarqueurs protéiques sanguins pour la détection précoce et précise du cancer
CN115678984B (zh) * 2022-10-14 2023-12-29 江西烈冰生物科技有限公司 狼疮性肾炎疗效评估用标志物及应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582921B2 (en) * 1996-07-29 2003-06-24 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses thereof
US6319607B1 (en) * 1998-11-10 2001-11-20 Bio-Pixels Ltd. Purification of functionalized fluorescent nanocrystals
US20020137108A1 (en) * 2000-11-08 2002-09-26 Michael Mullan CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker in alzheimer's disease
US6790501B2 (en) * 2002-07-23 2004-09-14 General Electric Company Limited-play optical media with improved shelf-life and playability
CN1245625C (zh) * 2003-04-30 2006-03-15 陕西西大北美基因股份有限公司 一种核/壳型超顺磁性复合微粒及其制备方法与应用
US20050214803A1 (en) * 2003-11-06 2005-09-29 Sru Biosystems, Llc High-density amine-functionalized surface
US20070243137A1 (en) * 2006-04-18 2007-10-18 Nanoprobes, Inc. Cell and sub-cell methods for imaging and therapy
US20120164717A1 (en) * 2007-07-18 2012-06-28 Joseph Irudayaraj Identity profiling of cell surface markers
WO2009117168A2 (fr) * 2008-01-03 2009-09-24 University Of Central Florida Research Foundation, Inc. Détection d'analytes utilisant des sondes de nanoparticules métalliques et une diffusion dynamique de la lumière
US20110190157A1 (en) * 2008-08-15 2011-08-04 The Regents Of The University Of California Biomarkers for Diagnosis and Treatment of Chronic Lymphocytic Leukemia
EP2529238A4 (fr) * 2010-01-28 2014-10-08 The Regents Of The University Of Michigan Dispositifs, systèmes et/ou procédés pour cultures en gouttes suspendues
US10139613B2 (en) * 2010-08-20 2018-11-27 Sakura Finetek U.S.A., Inc. Digital microscope and method of sensing an image of a tissue sample
WO2012046157A1 (fr) * 2010-10-05 2012-04-12 Koninklijke Philips Electronics N.V. Appareil et procédé pour localiser des particules magnétiques
CA2820933A1 (fr) * 2010-12-09 2012-06-14 Andries J.C. Steyn Biomarqueurs pour la tuberculose et le vih/sida
US9605320B2 (en) * 2011-01-13 2017-03-28 The Board Of Trustees Of The Leland Stanford Junior University Method of predicting responsiveness of B cell lineage malignancies to active immunotherapy
CH705758B1 (fr) * 2011-11-15 2016-03-31 Metalor Technologies Int Nanoparticules cœur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules.
KR20130113575A (ko) * 2012-04-06 2013-10-16 서울대학교산학협력단 산화철 나노복합체와 이를 포함하는 자기공명영상 ｔ2 조영제 및 이들의 제조 방법
US20140087397A1 (en) * 2012-09-25 2014-03-27 Children's Hospital Medical Center Biomarkers for fanconi anemia
ES2639559T3 (es) * 2012-12-28 2017-10-27 Ventana Medical Systems, Inc. Análisis de imágenes para el pronóstico de cáncer de mama
US10350320B2 (en) * 2013-01-29 2019-07-16 Children's Medical Center Corporation Magnetic separation using nanoparticles
CN105209909B (zh) * 2013-05-14 2019-06-07 梅塔博隆股份有限公司 与肾功能相关的生物标记及其使用方法

Also Published As

Publication number Publication date
CN108601525A (zh) 2018-09-28
WO2017062646A1 (fr) 2017-04-13
US20170234874A1 (en) 2017-08-17

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