SG11201802925YA - Integrated visual morphology and cell protein expression using resonance-light scattering - Google Patents

Integrated visual morphology and cell protein expression using resonance-light scattering

Info

Publication number
SG11201802925YA
SG11201802925YA SG11201802925YA SG11201802925YA SG11201802925YA SG 11201802925Y A SG11201802925Y A SG 11201802925YA SG 11201802925Y A SG11201802925Y A SG 11201802925YA SG 11201802925Y A SG11201802925Y A SG 11201802925YA SG 11201802925Y A SG11201802925Y A SG 11201802925YA
Authority
SG
Singapore
Prior art keywords
resonance
light scattering
protein expression
cell protein
integrated visual
Prior art date
Application number
SG11201802925YA
Inventor
Stephen Roman Fait
Eric Scott Mccampbell
Thomas H Adams
Michelle Brooke Mccampbell
Edward Jablonski
Robert Earl Klem
Original Assignee
Clearbridge Biophotonics Pte Ltd
Thomas H Adams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clearbridge Biophotonics Pte Ltd, Thomas H Adams filed Critical Clearbridge Biophotonics Pte Ltd
Publication of SG11201802925YA publication Critical patent/SG11201802925YA/en

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG11201802925YA 2015-10-07 2016-10-06 Integrated visual morphology and cell protein expression using resonance-light scattering SG11201802925YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562238605P 2015-10-07 2015-10-07
PCT/US2016/055789 WO2017062646A1 (en) 2015-10-07 2016-10-06 Integrated visual morphology and cell protein expression using resonance-light scattering

Publications (1)

Publication Number Publication Date
SG11201802925YA true SG11201802925YA (en) 2018-05-30

Family

ID=58488504

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201802925YA SG11201802925YA (en) 2015-10-07 2016-10-06 Integrated visual morphology and cell protein expression using resonance-light scattering

Country Status (4)

Country Link
US (1) US20170234874A1 (en)
CN (1) CN108601525A (en)
SG (1) SG11201802925YA (en)
WO (1) WO2017062646A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10401346B2 (en) * 2016-09-16 2019-09-03 Rachel Olema Aitaru Mobile sickle cell diagnostic tool
KR102256570B1 (en) * 2017-01-31 2021-05-27 한양대학교 산학협력단 Methods for detecting endocrine disruptors using dual modes of colorimetric and fluorometric analysis
CN111033260A (en) * 2017-06-30 2020-04-17 韩国化学研究院 Diagnostic kit for sepsis and diagnostic method using the same
CN107475202A (en) * 2017-08-18 2017-12-15 河南省肿瘤医院 A kind of lung cancer circulating tumor cell capture and Activity determination, analysis method and its application
CA3062226A1 (en) * 2018-05-25 2019-11-25 Illumina, Inc. Circulating rna signatures specific to preeclampsia
WO2020043693A1 (en) * 2018-08-29 2020-03-05 Westfälische Wilhelms-Universität Münster Diagnosis of multiple sclerosis
WO2020068905A1 (en) * 2018-09-25 2020-04-02 Northwestern University Stabilization of colloidal crystals engineered with nucleic acid
CN110553888B (en) * 2019-09-16 2022-07-12 中国农业科学院特产研究所 Method for rapid tabletting of oocyte after immunofluorescence staining
JP2023501760A (en) 2019-11-22 2023-01-19 イルミナ インコーポレイテッド A circulating RNA signature specific to pre-eclampsia
IL296714A (en) * 2020-03-27 2022-11-01 Univ Indiana Trustees Immunotherapeutic targets in multiple myeloma and methods for their identification
CN111693445A (en) * 2020-06-05 2020-09-22 北京卓诚惠生生物科技股份有限公司 Method for detecting immune cells in sputum
CN111821283B (en) * 2020-07-23 2021-11-30 华侨大学 Zinc glutamate-coated Prussian blue nanoparticles loaded with triphenylphosphine-lonidamine and wrapped by cancer cell membrane and preparation method of zinc glutamate-coated Prussian blue nanoparticles
CN114076721B (en) * 2020-08-12 2023-09-12 宝山钢铁股份有限公司 Method for detecting service life of steel plate chromium plating solution
CN112345755B (en) * 2020-09-23 2023-06-16 杭州凯保罗生物科技有限公司 Biomarker for breast cancer and application thereof
US20240036045A1 (en) * 2020-12-22 2024-02-01 The Brigham And Women`S Hospital, Inc. Blood-based protein biomarker panel for early and accurate detection of cancer
CN115678984B (en) * 2022-10-14 2023-12-29 江西烈冰生物科技有限公司 Marker for lupus nephritis curative effect evaluation and application

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582921B2 (en) * 1996-07-29 2003-06-24 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses thereof
US6319607B1 (en) * 1998-11-10 2001-11-20 Bio-Pixels Ltd. Purification of functionalized fluorescent nanocrystals
US20020137108A1 (en) * 2000-11-08 2002-09-26 Michael Mullan CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker in alzheimer's disease
US6790501B2 (en) * 2002-07-23 2004-09-14 General Electric Company Limited-play optical media with improved shelf-life and playability
CN1245625C (en) * 2003-04-30 2006-03-15 陕西西大北美基因股份有限公司 Nuclear/shell type superparamagnetism composite particulate, preparation method and application thereof
AU2004290375A1 (en) * 2003-11-06 2005-05-26 Sru Biosystems, Inc. High-density amine-functionalized surface
US20070243137A1 (en) * 2006-04-18 2007-10-18 Nanoprobes, Inc. Cell and sub-cell methods for imaging and therapy
US20120164717A1 (en) * 2007-07-18 2012-06-28 Joseph Irudayaraj Identity profiling of cell surface markers
US8883094B2 (en) * 2008-01-03 2014-11-11 University Of Central Florida Research Foundation, Inc. Detection of analtyes using metal nanoparticle probes and dynamic light scattering
WO2010019921A2 (en) * 2008-08-15 2010-02-18 The Regents Of The University Of California Biomarkers for diagnosis and treatment of chronic lymphocytic leukemia
CA2788575C (en) * 2010-01-28 2015-04-21 Shuichi Takayama Hanging drop devices, systems and/or methods
US10139613B2 (en) * 2010-08-20 2018-11-27 Sakura Finetek U.S.A., Inc. Digital microscope and method of sensing an image of a tissue sample
WO2012046157A1 (en) * 2010-10-05 2012-04-12 Koninklijke Philips Electronics N.V. Apparatus and method for locating magnetic particles
JP2014500504A (en) * 2010-12-09 2014-01-09 アドリース ジェイ．シー スタイン， Biomarkers for tuberculosis and HIV / AIDS
US9605320B2 (en) * 2011-01-13 2017-03-28 The Board Of Trustees Of The Leland Stanford Junior University Method of predicting responsiveness of B cell lineage malignancies to active immunotherapy
CH705758B1 (en) * 2011-11-15 2016-03-31 Metalor Technologies Int Nanoparticles heart-shell silica-metal, manufacturing process and test device immunochromatography comprising such nanoparticles.
KR20130113575A (en) * 2012-04-06 2013-10-16 서울대학교산학협력단 Iron oxide nanocomposite, mri t2 contrast agent comprising the same and process for preparing the sames
US20140087397A1 (en) * 2012-09-25 2014-03-27 Children's Hospital Medical Center Biomarkers for fanconi anemia
ES2639559T3 (en) * 2012-12-28 2017-10-27 Ventana Medical Systems, Inc. Image analysis for breast cancer prognosis
WO2014120794A1 (en) * 2013-01-29 2014-08-07 Massachusetts Institute Of Technology Magnetic separation using nanoparticles
WO2014186311A1 (en) * 2013-05-14 2014-11-20 Metabolon, Inc. Biomarkers related to kidney function and methods using the same

Also Published As

Publication number Publication date
WO2017062646A1 (en) 2017-04-13
CN108601525A (en) 2018-09-28
US20170234874A1 (en) 2017-08-17

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