SG11201800148VA - Simplified and scalable method for synthesis of 2,6-bis(methionyl)-1,4-diketopiperazine - Google Patents

Simplified and scalable method for synthesis of 2,6-bis(methionyl)-1,4-diketopiperazine

Info

Publication number
SG11201800148VA
SG11201800148VA SG11201800148VA SG11201800148VA SG11201800148VA SG 11201800148V A SG11201800148V A SG 11201800148VA SG 11201800148V A SG11201800148V A SG 11201800148VA SG 11201800148V A SG11201800148V A SG 11201800148VA SG 11201800148V A SG11201800148V A SG 11201800148VA
Authority
SG
Singapore
Prior art keywords
diketopiperazine
methionyl
bis
synthesis
simplified
Prior art date
Application number
SG11201800148VA
Other languages
English (en)
Inventor
Sascha Braune
Daniel Rost
Juergen Bilz
Thomas Haeussner
Hans Joachim Hasselbach
Christoph Kobler
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of SG11201800148VA publication Critical patent/SG11201800148VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SG11201800148VA 2015-07-09 2016-06-28 Simplified and scalable method for synthesis of 2,6-bis(methionyl)-1,4-diketopiperazine SG11201800148VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15176058 2015-07-09
PCT/EP2016/064982 WO2017005547A1 (de) 2015-07-09 2016-06-28 Vereinfachtes und skalierfähiges verfahren zur synthese von 2,6-bis(methionyl)-1,4-diketopiperazin

Publications (1)

Publication Number Publication Date
SG11201800148VA true SG11201800148VA (en) 2018-02-27

Family

ID=53773212

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201800148VA SG11201800148VA (en) 2015-07-09 2016-06-28 Simplified and scalable method for synthesis of 2,6-bis(methionyl)-1,4-diketopiperazine

Country Status (7)

Country Link
US (1) US20180194804A1 (ru)
EP (1) EP3319946A1 (ru)
JP (1) JP2018521065A (ru)
CN (1) CN107922355B (ru)
RU (1) RU2018104882A (ru)
SG (1) SG11201800148VA (ru)
WO (1) WO2017005547A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4151643A1 (en) 2021-09-16 2023-03-22 Evonik Operations GmbH Improved process for production of phosphoesters of glufosinate precursors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2261926C3 (de) * 1972-12-18 1978-11-30 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Verfahren zur Herstellung von DL-Methionyl-DL-methionin
GB2096149B (en) * 1981-02-26 1984-07-18 Ajinomoto Kk Stabilized halogen-containing resin compositions
MXPA06005638A (es) * 2003-11-19 2006-08-17 Pharmacia & Upjohn Co Llc Sintesis de 2-cloro-3, 6-dialquilpirazinas.
JP4968848B2 (ja) * 2008-01-30 2012-07-04 株式会社Ａｄｅｋａ ポリオレフィン樹脂組成物
DE102008042932A1 (de) * 2008-10-17 2010-04-22 Evonik Degussa Gmbh Herstellung und Verwendung von Methionylmethionin als Futtermitteladditiv für Fische und Krustentiere
DE102009002044A1 (de) * 2009-03-31 2010-10-07 Evonik Degussa Gmbh Dipeptide als Futtermitteladditive
DE102010029399A1 (de) * 2010-05-27 2011-12-01 Evonik Degussa Gmbh Cyclische Dipeptide als Futtermitteladditive

Also Published As

Publication number Publication date
US20180194804A1 (en) 2018-07-12
CN107922355B (zh) 2020-12-15
RU2018104882A (ru) 2019-08-09
JP2018521065A (ja) 2018-08-02
EP3319946A1 (de) 2018-05-16
WO2017005547A1 (de) 2017-01-12
CN107922355A (zh) 2018-04-17

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