SG11201710596RA - Pyrazole derivative or pharmaceutically acceptable salt thereof - Google Patents
Pyrazole derivative or pharmaceutically acceptable salt thereofInfo
- Publication number
- SG11201710596RA SG11201710596RA SG11201710596RA SG11201710596RA SG11201710596RA SG 11201710596R A SG11201710596R A SG 11201710596RA SG 11201710596R A SG11201710596R A SG 11201710596RA SG 11201710596R A SG11201710596R A SG 11201710596RA SG 11201710596R A SG11201710596R A SG 11201710596RA
- Authority
- SG
- Singapore
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- pyrazole derivative
- pyrazole
- derivative
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A61K31/4192—1,2,3-Triazoles
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- A—HUMAN NECESSITIES
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- A61K31/4196—1,2,4-Triazoles
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- A—HUMAN NECESSITIES
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- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015126046 | 2015-06-23 | ||
PCT/JP2016/068445 WO2016208602A1 (ja) | 2015-06-23 | 2016-06-22 | ピラゾール誘導体、またはその薬理学的に許容される塩 |
Publications (1)
Publication Number | Publication Date |
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SG11201710596RA true SG11201710596RA (en) | 2018-01-30 |
Family
ID=57586369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SG11201710596RA SG11201710596RA (en) | 2015-06-23 | 2016-06-22 | Pyrazole derivative or pharmaceutically acceptable salt thereof |
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US (1) | US10287251B2 (de) |
EP (2) | EP3315492B1 (de) |
JP (1) | JP6454418B2 (de) |
KR (1) | KR102655928B1 (de) |
CN (1) | CN107709301B (de) |
AU (1) | AU2016281346B2 (de) |
BR (1) | BR112017028125A2 (de) |
CA (1) | CA2988772A1 (de) |
ES (1) | ES2820839T3 (de) |
IL (1) | IL256339B (de) |
MX (1) | MX2017016876A (de) |
MY (1) | MY195177A (de) |
PH (1) | PH12017502254A1 (de) |
PL (1) | PL3315492T3 (de) |
RU (1) | RU2687245C1 (de) |
SG (1) | SG11201710596RA (de) |
TW (1) | TWI681956B (de) |
WO (1) | WO2016208602A1 (de) |
ZA (1) | ZA201708611B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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JPWO2018117166A1 (ja) * | 2016-12-21 | 2019-10-31 | キッセイ薬品工業株式会社 | チアゾール誘導体、またはその薬理学的に許容される塩 |
JP6986955B2 (ja) * | 2016-12-28 | 2021-12-22 | キッセイ薬品工業株式会社 | ピラゾール誘導体の製造方法 |
CN109748873B (zh) * | 2017-11-08 | 2021-02-02 | 北京嘉林药业股份有限公司 | 化合物及其治疗癌症的用途 |
US20240132487A1 (en) * | 2019-10-17 | 2024-04-25 | Givaudan Sa | Substituted azacyles as trmp8 modulators |
CN117813077A (zh) | 2021-08-16 | 2024-04-02 | 西姆莱斯股份公司 | 组合物 |
CN114394934B (zh) * | 2022-01-06 | 2023-06-13 | 苏州大学 | 吡唑苯甲酰胺类化合物及其制备方法和应用 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL39092A (en) * | 1971-04-22 | 1976-02-29 | Du Pont | Pyrazole derivatives and their use as plant growth regulants |
JP2000256358A (ja) | 1999-03-10 | 2000-09-19 | Yamanouchi Pharmaceut Co Ltd | ピラゾール誘導体 |
CA2381975A1 (en) | 1999-08-19 | 2001-02-22 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
PT1282418E (pt) * | 2000-05-19 | 2005-10-31 | Applied Research Systems | Utilizacao de derivados pirazolo para o tratamento da infertilidade |
AU2001273040A1 (en) | 2000-06-27 | 2002-01-08 | Du Pont Pharmaceuticals Company | Factor xa inhibitors |
AU2003262831A1 (en) | 2002-08-23 | 2004-03-11 | Rigel Pharmaceuticals, Inc. | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
US20040215284A1 (en) | 2003-01-30 | 2004-10-28 | Recordati S.A. | Treatment of neuromuscular dysfunction of the lower urinary tract with selective mGlu5 antagonists |
ITMI20030151A1 (it) * | 2003-01-30 | 2004-07-31 | Recordati Ind Chimica E Farma Ceutica S P A | Uso di antagonisti selettivi del recettore mglu5 per il trattamento di disfunzioni neuromuscolari del tratto urinario inferiore. |
WO2004099164A1 (en) * | 2003-05-02 | 2004-11-18 | Rigel Pharmaceuticals, Inc. | Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating hcv infection |
US8329703B2 (en) | 2005-02-15 | 2012-12-11 | Xtl Biopharmaceuticals Ltd. | Pyrazole compounds |
WO2007017093A1 (en) * | 2005-08-04 | 2007-02-15 | Bayer Healthcare Ag | Substituted 2-benzyloxy-benzoic acid amide derivatives |
WO2007061923A2 (en) | 2005-11-18 | 2007-05-31 | Takeda San Diego, Inc. | Glucokinase activators |
MX2010000690A (es) * | 2007-07-18 | 2010-06-25 | Janssen Pharmaceutica Nv | Sulfonamidas como moduladores de trpm8. |
DE102007040243A1 (de) * | 2007-08-25 | 2009-02-26 | Universität des Saarlandes | 17Beta-Hydroxysteriod-Dehydrogenase Typ1 Inhibitoren zur Behandlung hormonabhängiger Erkrankungen |
US8680275B2 (en) | 2009-10-23 | 2014-03-25 | Janssen Pharmaceutica Nv | Fused heterocyclic compounds as orexin receptor modulators |
US8680098B2 (en) * | 2010-03-05 | 2014-03-25 | Janssen Pharmaceutica, Nv | Substituted aza-bicyclic imidazole derivatives useful as TRPM8 receptor modulators |
BR112013011188B1 (pt) * | 2010-11-05 | 2022-01-04 | Senomyx, Inc | Método não-médico para modular canal potencial de receptor transiente de melastina 8 (trpm8), método não-médico para modular a sensação de resfriamento de uma composição, método não-médico para induzir uma sensação de resfriamento em um humano ou animal e composto |
US9365588B2 (en) | 2011-11-04 | 2016-06-14 | Vertex Pharmaceuticals Incorporated | Benzoxazines as modulators of ion channels |
MX362192B (es) * | 2013-05-08 | 2019-01-08 | Kissei Pharmaceutical | Derivado de glicinamida alfa-sustituida. |
-
2016
- 2016-06-22 TW TW105119545A patent/TWI681956B/zh not_active IP Right Cessation
- 2016-06-22 RU RU2017145176A patent/RU2687245C1/ru active
- 2016-06-22 SG SG11201710596RA patent/SG11201710596RA/en unknown
- 2016-06-22 US US15/736,016 patent/US10287251B2/en active Active
- 2016-06-22 EP EP16814372.5A patent/EP3315492B1/de active Active
- 2016-06-22 CA CA2988772A patent/CA2988772A1/en not_active Abandoned
- 2016-06-22 JP JP2017524933A patent/JP6454418B2/ja active Active
- 2016-06-22 EP EP20161313.0A patent/EP3686188B1/de active Active
- 2016-06-22 BR BR112017028125-2A patent/BR112017028125A2/pt not_active IP Right Cessation
- 2016-06-22 CN CN201680037397.9A patent/CN107709301B/zh active Active
- 2016-06-22 ES ES16814372T patent/ES2820839T3/es active Active
- 2016-06-22 WO PCT/JP2016/068445 patent/WO2016208602A1/ja active Application Filing
- 2016-06-22 KR KR1020187002023A patent/KR102655928B1/ko active IP Right Grant
- 2016-06-22 MX MX2017016876A patent/MX2017016876A/es unknown
- 2016-06-22 AU AU2016281346A patent/AU2016281346B2/en not_active Ceased
- 2016-06-22 MY MYPI2017704878A patent/MY195177A/en unknown
- 2016-06-22 PL PL16814372T patent/PL3315492T3/pl unknown
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2017
- 2017-12-11 PH PH12017502254A patent/PH12017502254A1/en unknown
- 2017-12-14 IL IL256339A patent/IL256339B/en active IP Right Grant
- 2017-12-18 ZA ZA2017/08611A patent/ZA201708611B/en unknown
Also Published As
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EP3686188B1 (de) | 2022-04-06 |
US20180170879A1 (en) | 2018-06-21 |
IL256339B (en) | 2020-03-31 |
KR102655928B1 (ko) | 2024-04-09 |
AU2016281346B2 (en) | 2020-01-02 |
IL256339A (en) | 2018-02-28 |
CN107709301B (zh) | 2021-06-22 |
WO2016208602A1 (ja) | 2016-12-29 |
JPWO2016208602A1 (ja) | 2018-04-12 |
BR112017028125A2 (pt) | 2018-08-28 |
EP3315492A4 (de) | 2018-12-19 |
MX2017016876A (es) | 2018-04-10 |
CA2988772A1 (en) | 2016-12-29 |
KR20180015262A (ko) | 2018-02-12 |
EP3315492A1 (de) | 2018-05-02 |
PH12017502254B1 (en) | 2018-06-11 |
ZA201708611B (en) | 2019-05-29 |
PL3315492T3 (pl) | 2021-04-06 |
AU2016281346A1 (en) | 2018-01-18 |
PH12017502254A1 (en) | 2018-06-11 |
MY195177A (en) | 2023-01-11 |
EP3315492B1 (de) | 2020-09-16 |
CN107709301A (zh) | 2018-02-16 |
EP3686188A1 (de) | 2020-07-29 |
JP6454418B2 (ja) | 2019-01-16 |
ES2820839T3 (es) | 2021-04-22 |
TW201712004A (zh) | 2017-04-01 |
TWI681956B (zh) | 2020-01-11 |
RU2687245C1 (ru) | 2019-05-08 |
US10287251B2 (en) | 2019-05-14 |
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